Clinical Trials on Ascorbic Acid Deficiency

Total 9973 results

Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Management in Intensive Care Unit of Life-threatening Keto-Acidosis (MILKA)

Ketoacidosis

France
SciVision Biotech Inc.

Completed

The Evaluation of the Safety and Effectiveness of ANIMERS Chiara LA and JUVÉDERM VOLUMA® for Aging Mid-Face

Lidocaine | Hyaluronic Acid | Dermal Filler | Aging Mid-Face

Taiwan
University of Cologne

Completed

Short Term Induction of Ketosis in PKD (RESET-PKD)

ADPKD

Germany
Western University, Canada

Unknown

Exogenous Ketone Supplementation and Exercise Performance

Ketosis | Ketonemia

Canada
Université de Sherbrooke

Completed

PET Study of Cerebral Metabolism of 11C-acetoacetate and 18F-FDG in Patients Under Moderate Ketosis (TEP-KD)

Healthy
University Hospital Schleswig-Holstein

Completed

Effect of Propofol and Sevoflurane on Lactate During Anesthesia for Pediatric Heart Catheterisation (PRISCATHLAB)

Metabolic Acidosis

Germany
HemoShear Therapeutics
Prometrika, LLC; AllStripes Research Inc.; Genome Medical

Terminated

Natural History Study of Patients With Methylmalonic Acidemia and Propionic Acidemia (JUMP)

Propionic Acidemia | Methylmalonic Acidemia

United States, Canada, United Kingdom
HemoShear Therapeutics

Terminated

Study of HST5040 in Subjects With Propionic or Methylmalonic Acidemia (HERO)

Propionic Acidemia | Methylmalonic Acidemia

United States, Saudi Arabia, Australia
King Abdullah International Medical Research Center

Completed

Carglumic Acid in Methylmalonic Acidemia and Propionic Acidemia (CAMP)

Propionic Acidemia | Methylmalonic Acidemia

Saudi Arabia
Mendel Tuchman
University of Colorado, Denver; Children's Hospital of Philadelphia; University... and other collaborators

Terminated

Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia

Propionic Acidemia | Methylmalonic Acidemia

United States
University of Pennsylvania

Recruiting

Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging

Healthy

United States
Taipei Medical University Hospital

Recruiting

The Causal Connection Between Sng and Muscle Acidosis

Muscle Acidosis

Taiwan
University of Surrey
FrieslandCampina

Recruiting

The Role of the Microbiota-gut-brain Axis in Brain Development and Mental Health

Anxiety | Gamma-Aminobutyric Acid | Glutamate | Emotion Regulation Abilities

United Kingdom
Augusta University

Unknown

Ketone Supplementation in Individuals With PTSD

PTSD | Ketosis

United States
New York Institute of Technology

Completed

Whole Body Periodic Acceleration on Blood Lactate and Recovery

Acidosis, Lactic

United States
Ohio State University

Completed

Tranexamic Acid Use and Blood Loss in Total Hip Arthroplasty

Blood Loss | Tranexamic Acid Use

United States
Orphanetics Pharma Entwicklungs GmbH

Terminated

Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety

Phenylalanine Hydroxylase Deficiencies
Genzyme, a Sanofi Company

Completed

A Study of rhGAA in Patients With Late-Onset Pompe Disease

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

Netherlands
Genzyme, a Sanofi Company

Completed

Safety and Effectiveness Study of rhGAA in Patients With Advanced Late-Onset Pompe Disease Receiving Respiratory Support

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

France
University Hospital, Montpellier

Recruiting

Value of Fetal Scalp Lactate Sampling During Labour in Cases of Abnormal Fetal Heart Rate

Metabolic Acidosis

France
Taipei Medical University Hospital

Recruiting

Effect of Flow Rate and pH on Muscle Acidosis

Muscle Acidosis

Taiwan
McMaster University

Not yet recruiting

Topical Tranexamic Acid for Bilateral Breast Reduction Surgery

Hematoma Postoperative | Tranexamic Acid

Canada
SciVision Biotech Inc.

Completed

The Evaluation of the Safety and Effectiveness of a Novel Gel-type Sodium Hyaluronate for the Correction of Aging Mid-face

Lidocaine | Hyaluronic Acid | Dermal Filler | Aging Mid-Face

Taiwan
University of Edinburgh
NHS Lothian

Unknown

Intraoperative Cell Salvage and Postoperative Acidosis

Metabolic Acidosis

United Kingdom
Brock University

Completed

Chronic Versus Acute Dosing of Sodium Citrate for Swimming 200m

Alkalosis

Canada
University Hospital Schleswig-Holstein

Completed

Substitution of Propofol by Sevoflurane During Pediatric Cardiopulmonary Bypass (PRISKIKO)

Metabolic Acidosis

Germany
Royal Marsden NHS Foundation Trust

Unknown

Incidence of Postoperative Ketosis and Metabolic Acidosis (POKACID)

Metabolic Acidosis

United Kingdom
Central Hospital, Nancy, France

Not yet recruiting

Hyperhomocysteinemia in Alzheimer's Disease (Hcy-MA)

Alzheimer Disease | Homocystinemia
Universidade Estadual de Londrina

Completed

Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events

Cardiovascular Disease | Hemodialysis | Chronic Renal Failure | Uremia | Hyperhomocysteinemia

Brazil
Recordati Rare Diseases

Recruiting

Understanding the Long-Term Management of Organic Acidemia Patients With CARBAGLU®: A Mixed Methods Approach (PROTECT)

Propionic Acidemia | Methylmalonic Acidemia

France, Spain, Italy, United Kingdom, Norway, Germany, Sweden
Enzyvant Therapeutics GmBH

Completed

Farber Disease Natural History Study

Farber Disease | Farber's Disease | Farber Lipogranulomatosis | Acid Ceramidase Deficiency | Ceramidase Deficiency | N-Laurylsphingosine Deacylase Deficiency | ASAH1 Mutation

United States, Egypt, Canada, Italy, Turkey, Argentina, Germany, India, Sweden
Genzyme, a Sanofi Company

Completed

A Placebo-Controlled Study of Safety and Effectiveness of Myozyme (Alglucosidase Alfa) in Patients With Late-Onset Pompe Disease

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

United States, France, Netherlands
Beijing Tongren Hospital

Completed

Application of High-flow Nasal Oxygen in Cesarean Section

Fetal Acidemia

China
Rajavithi Hospital

Withdrawn

Efficacy of Topical 95% TCA in the Treatment of CIN 1 or Less After Low-grade Abnormality of Screening Test

CIN1 | Trichloroacetic Acid

Thailand
University of Alabama at Birmingham

Completed

Acceptability and Tolerability of Ketone Supplements and Effects of BHB Concentrations in Young Adults

Exogenous Ketosis

United States
KU Leuven

Active, not recruiting

Role of Intermittent Exogenous Ketosis in the Physiological and Muscular Adaptive Response to Endurance Training

Exercise Adaptations

Belgium
Nick Emanuele

Withdrawn

The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery (TXA-OMFS)

Orthognathic Surgery | Tranexamic Acid

Canada
Amphia Hospital

Completed

The Effect on Blood Loss of Topical and Intravenous Tranexamic Acid in Cardiac Surgery Patients

Blood Loss | Cardiac Surgery | Tranexamic Acid

Netherlands
AstraZeneca

Completed

Survey Examining the Frequency and Severity of Acid Related Symptoms While Taking Nexium

Proton Pump Inhibitors | Gastric Acid Suppression

Albania
Children's Hospital Medical Center, Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up

Wolman Disease | Cholesterol Ester Storage Disease | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

United States
Shenzhen Geno-Immune Medical Institute

Unknown

Gene Transfer for ADA-SCID Using an Improved Lentiviral Vector (TYF-ADA)

Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)

China
Changi General Hospital

Completed

The Threshold of Serum Anion Gap as a Screening Tool for Organic Acidosis

Critical Illness | Metabolic Acidosis | Anion Gap Acidosis | Lactic Acidosis | Keto Acidosis | Acid Base Disorder

Singapore
Hospital Universitario Dr. Jose E. Gonzalez
Laboratorios Valdecasas S.A.

Completed

The Effect of Folic Acid Administration in the Progression of Microalbuminuria

Diabetic Nephropathies | Hyperhomocysteinemia

Mexico
Imperial College Healthcare NHS Trust

Completed

Obeticholic Acid in Bile Acid Diarrhoea (OBADIAH1)

Primary Bile Acid Malabsorption | Secondary Bile Acid Malabsorption | Chronic Diarrhoea

United Kingdom
National Human Genome Research Institute (NHGRI)

Recruiting

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Propionic Acidemia | Metabolic Disease | Organic Acidemia

United States
ModernaTX, Inc.

Completed

"The MaP Study": Mapping the Patient Journey in MMA and PA

Propionic Acidemia | Methylmalonic Acidemia

United States, United Kingdom, Spain, France
University of Oxford

Recruiting

Exogenous Ketosis in a Fed and a Fasted State

Ketosis | Exogenous Ketosis

United Kingdom
AdventHealth Translational Research Institute

Recruiting

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers (CASINO)

Ketones, Metabolism

United States
Instituto Nacional de Ciencias Medicas y Nutricion...
American Ketone LLC

Recruiting

Evaluation of the Safety and Tolerability of Exogenous Ketosis Induced by Free Beta-hydroxybutyrate.

Exogenous Ketosis

Mexico
Bezmialem Vakif University

Completed

Effectiveness Of Tranexamic Acıd Application Wıth Different Doses On Bleeding, Edema And Physician Comfort In Orthognathıc Surgery Patients

Edema | Bleeding | Orthognathic Surgery | Tranexamic Acid

Turkey

Clinical Trials on Ascorbic Acid Deficiency

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CROs in Netherlands

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Rare Diseases

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