Clinical Trials on Asplenia

Total 269 results

International Extranodal Lymphoma Study Group (IELSG)

Not yet recruiting

Comparison Between Rituximab Plus Zanubrutinib Versus Rituximab Monotherapy in Untreated SMZL Patients (RITZ)

Splenic Marginal Zone Lymphoma

Norway, Denmark, Sweden, Italy, Switzerland
Koneti Rao

Completed

Valproic Acid (Depakote[Registered Trademark]) to Treat Autoimmune Lymphoproliferative Syndrome (ALPS)

Lymphadenopathy | Hypersplenism | ALPS

United States
University College Absalon
University of Southern Denmark; Danish Council for Independent Research; Sundhed...

Completed

Physical Function of Older Citizens During Municipality-based Rehabilitation

Fractures, Bone | Musculoskeletal Diseases | Musculoskeletal Pain | Muscle Weakness | Frailty | Sarcopenia | Aging | Rehabilitation | Musculoskeletal Injury | Weakness, Muscle

Denmark
International Extranodal Lymphoma Study Group (IELSG)

Completed

Integrated Molecular and Clinical Profiling to Optimize Outcome Prediction in Splenic Marginal Zone Lymphoma

Splenic Marginal Zone Lymphoma

Switzerland
University of Chile

Completed

Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock

Septic Shock | Muscle Weakness | Polyneuropathies
Qilu Hospital of Shandong University

Enrolling by invitation

A Randomized Controlled Study on the Treatment of Cirrhosis Combined With Hypersplenism

Liver Cirrhosis | Esophageal and Gastric Varices | Hypersplenism

China
Narendranath Epperla

Withdrawn

Acalabrutinib and Duvelisib for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Recurrent Marginal Zone Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Refractory Nodal Marginal Zone Lymphoma | Recurrent Nodal Marginal Zone Lymphoma | Recurrent Splenic Marginal Zone Lymphoma | Refractory Splenic Marginal Zone Lymphoma and other conditions
Materia Medica Holding

Completed

Сlinical Trial of Efficacy and Safety of Prospekta in the Treatment of Post-COVID-19 Asthenia.

Post-acute COVID-19 Syndrome

Russian Federation
Hospital Felix Bulnes

Completed

Efficacy of the "Start to Move" Protocol on Functionality, Delirium and Acquired Weakness in ICU (STM)

Mechanical Ventilation Complication | Intensive Care Unit Syndrome | Intensive Care Unit Acquired Weakness | Intensive Care Unit Delirium | Intensive Care Neuropathy

Chile
Children's Healthcare of Atlanta

Terminated

Racial Distribution of Heterotaxy Syndrome

Congenital Disorders

United States
Koç University

Recruiting

Telerehabilitation in Proximal Muscle Weakness

Muscular Dystrophies | Telemedicine | Proximal Myopathy

Turkey
Swiss Federal Institute of Technology

Completed

Evaluation of a Textile Scapula Orthosis (ScapOrthosis)

Muscle Weakness | Muscular Dystrophies | Muscular Dystrophy | Muscular Dystrophy, Facioscapulohumeral | Scapular Dyskinesis | Muscular Weakness

Germany, Switzerland
Technical University of Munich
Charite University, Berlin, Germany; Helmholtz Zentrum München

Recruiting

Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness (MIRACLE I)

Critical Illness | Muscle Weakness | Critical Illness Myopathy | Critical Care | Critical Illness Polyneuropathy | Metabolomics | Intensive Care (ICU) Myopathy

Germany
University of Oregon
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

Syndrome | Pain | Muscle Weakness | Tendinopathy | Shoulder Pain | Acute Pain | Impairment | Goals | Pathology | Injury | Infiltration | Atrophic

United States
Orthocare Innovations, LLC
National Institute on Disability, Independent Living, and Rehabilitation...

Recruiting

mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation

Stroke | Upper Limb Amputation | Upper Limb Weakness Due to Central Neurologic Injury | Upper Limb Weakness Due to Peripheral Neurologic Injury | Upper Limb Weakness Due to Nerve Reconstruction | Upper Limb Weakness Due to Tendon Transfer Surgery

United States
University of Alberta

Completed

Heterotaxy Syndrome and Intestinal Rotation Abnormalities - A Prospective Study

Heterotaxy Syndrome

Canada
Technical University of Munich
Helmholtz Zentrum München

Completed

Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma (MIRACLE II)

Critical Illness | Muscle Weakness | Critical Illness Myopathy | Critical Care | Critical Illness Polyneuropathy | Metabolomics | Intensive Care (ICU) Myopathy

Germany
Imperial College London
Medical Research Council; Royal Brompton & Harefield NHS Foundation Trust

Terminated

Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension

Muscle Weakness | Pulmonary Arterial Hypertension

United Kingdom
Boston Children's Hospital
Litron Laboratories

Completed

Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data

Heterotaxy Syndrome

United States
International Extranodal Lymphoma Study Group (IELSG)

Active, not recruiting

MALIBU Trial - Combination of Ibrutinib and Rituximab in Untreated Marginal Zone Lymphomas (MALIBU)

Splenic Marginal Zone Lymphoma | Marginal Zone Lymphoma | Nodal Marginal Zone Lymphoma

France, Switzerland, Italy, Belgium, Portugal
HaEmek Medical Center, Israel

Completed

Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease (B-RAF V600E)

Splenic Marginal Zone Lymphoma | Hairy Cell Leukemia
Indiana University

Recruiting

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Congenital Heart Defects | Heterotaxy Syndrome

United States
Xijing Hospital
Air Force Military Medical University, China; Health Science Center of Xi'an...

Unknown

Study of the Impact of Hypersplenism and Splenectomy on Hepatocarcinogenesis in Patients With Posthepatitic Cirrhosis

Liver Cirrhosis | Carcinoma, Hepatocellular | Laparotomy | Splenomegaly

China
Jennifer Moreno Clinic

Unknown

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

Knee Osteoarthritis | Muscle Weakness | Muscle Weakness Condition | Knee Arthritis | Knee Pain Chronic | Knee Pain Swelling | Knee Deformity | Power

United States
Narendranath Epperla

Not yet recruiting

Pemigatinib for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma or Marginal Zone Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory Mantle Cell Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid... and other conditions

United States
Rutgers, The State University of New Jersey

Recruiting

YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility (YOOMI)

Physical Disability | Muscle Atrophy or Weakness | Muscle Loss | Physical Inactivity | Delirium in Old Age | Hospital Acquired Condition | Weakness, Muscle

United States
Promomed, LLC

Completed

Efficacy of the Therapy With BRAINMAX® Using fMRI for the Treatment of Patients With Asthenia After COVID-19

COVID-19 | Asthenia | Cognitive Impairment | Functional MRI

Russian Federation
Riphah International University

Completed

Incentive Spirometry and Upper Abdominal Laparoscopic Surgery

Hiatal Hernia | Cholecystitis | Choledocholithiasis | Splenomegaly | Diaphragmatic Hernia | Perforated Duodenal Ulcer | Malignant Pancreatic Neoplasm | Benign Pancreas Tumor | Splenic Infarction

Pakistan
Biocad

Completed

Safety and Efficacy Study of BCD-020 in Therapy of Indolent Non-Hodgkin's Lymphoma

Splenic Marginal Zone Lymphoma | Nodal Marginal Zone Lymphoma | Follicular Non-Hodgkin's Lymphoma

India, Russian Federation, Colombia, South Africa, Ukraine
Sidney Kimmel Cancer Center at Thomas Jefferson...
Genentech, Inc.; Pharmacyclics LLC.

Recruiting

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Indolent Non-hodgkin Lymphoma | Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage II Nodal Marginal Zone Lymphoma | Ann Abor Stage III B-Cell Non-Hodgkin Lymphoma | Ann Arbor... and other conditions

United States
Baylor College of Medicine
Avazzia, Inc

Completed

Electrical Stimulation for Critically Ill Post-Covid-19 Patients (Phase II)

COVID-19 | Muscle Weakness | Muscle Atrophy

United States
Baylor College of Medicine
Avazzia, Inc

Completed

Electrical Stimulation for Critically Ill Covid-19 Patients (Phase I)

Covid19 | Muscle Weakness | Muscle Atrophy

United States
University of Pavia
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

Completed

Muscle Weakness in COVID-19 Patients (MIOCOVID)

Covid19 | Muscle Weakness | SARS-CoV Infection | Exercise Intolerance

Italy
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism | Malignant Neoplasm | Portal Vein Thrombosis | Metastatic Malignant Neoplasm | Cerebral Vein Thrombosis | Renal Vein Thrombosis | Gonadal Thrombosis | Hepatic Thrombosis | Mesenteric Thrombosis | Splenic Thrombosis

United States
University of Chile
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile

Recruiting

Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing

Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication | ICU Acquired Weakness

Chile
Celal Bayar University
Saglik Bilimleri Universitesi; Dokuz Eylul University

Not yet recruiting

The Effects of Pelvic Floor Muscle Training and Balance Exercises in Elderly People With Incontinence

Urinary Incontinence | Muscle Weakness | Pelvic Floor Muscle Weakness

Turkey
National Human Genome Research Institute (NHGRI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study on Moebius Syndrome and Congenital Facial Weakness Disorders

Birth Defects | Brain Disorders | Craniofacial Differences

United States
Noha Khaled Shoukry

Active, not recruiting

Ankle Spine Syndrome "RAFFET Syndrome II

Chronic Low-back Pain | Lumbar Disc Herniation | Chronic Ankle Injuries | Calf Muscle Weakness

Egypt
Hospital de Clinicas de Porto Alegre
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Completed

Effects of Inspiratory Muscle Training on Type 2 Diabetes Mellitus Patients With Inspiratory Muscle Weakness

Diabetes Complications | Inspiratory Muscle Weakness

Brazil
French Study Group on Chronic Lymphoid Leukemia
French Innovative Leukemia Organisation; Lymphoma Study Association; Département...

Completed

Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia

Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia | Lymphoplasmacytic Lymphoma

France
Lifetech Scientific (Shenzhen) Co., Ltd.

Not yet recruiting

Cera™ Vascular Plug System Post-Market Clinical Follow-Up

Aneurysm | Portal Hypertension | Arteriovenous Fistula | Endoleak | Pulmonary Arteriovenous Malformation | Splenic Laceration
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Refractory Mantle Cell Lymphoma | Central Nervous System Lymphoma | Gastric Mantle Cell Lymphoma | Splenic Mantle Cell Lymphoma

United States
Lokman Hekim Üniversitesi
Hacettepe University

Completed

Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy

Quality of Life | Lower Urinary Tract Symptoms | Muscle Weakness | Duchenne Muscular Dystrophy | Pelvic Floor Muscle Weakness | Posture Disorders in Children | Lumbar Lordosis

Turkey
Deepa Jagadeesh

Recruiting

A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)

Angioimmunoblastic T-cell Lymphoma | T-cell Lymphoma | Adult T-cell Leukemia/Lymphoma | Enteropathy Associated T-cell Lymphoma | Hepato-splenic T-cell Lymphoma | NK T-cell Lymphoma

United States
Yazeed Sawalha

Withdrawn

Lenalidomide, Umbralisib, and Ublituximab for the Treatment of Relapsed or Refractory Indolent Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular... and other conditions
National Institute of Allergy and Infectious Diseases...

Completed

Dyskinesia, Heterotaxy and Congenital Heart Disease

Congenital Heart Defects | Situs Inversus | Kartagener Syndrome | Ciliary Dyskinesia, Primary

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Indolent Non-hodgkin Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Nodal Marginal Zone Lymphoma

United States
National Cancer Institute (NCI)

Withdrawn

Obatoclax Mesylate, Rituximab, and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma

United States
Robert Lowsky
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Intratumoral Injection of SD-101

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic...

United States

Clinical Trials on Asplenia

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