Clinical Trials on Atherosclerosis, Cerebral

Total 6997 results

Capital Medical University

Enrolling by invitation

Remote Ischemic Conditioning in Acute Ischemic Cerebral Vascular Disease Patients With Coexistence of Cerebral and Coronary Atherosclerosis（RIC-CCCA）

Acute Ischemic Cerebral Vascular Disease

China
David Grant U.S. Air Force Medical Center

Terminated

Assessment of Coronary Artery Calcium in Active Duty Enlisted Military Members With 10 or More Years of Service

Atherosclerosis | Plaque, Atherosclerotic

United States
Merck Sharp & Dohme LLC

Completed

Evaluate the Utility of 18FDG-PET as a Tool to Quantify Atherosclerotic Plaque (MK-0000-081 AM3)(COMPLETED)

Atherosclerotic Vascular Disease
Xuanwu Hospital, Beijing

Recruiting

Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA)

Coexistence of Cerebral and Coronary Atherosclerosis | Acute Ischemic Cerebrovascular Disease

China
Westside Medical Associates of Los Angeles
Regeneron Pharmaceuticals; University of Washington

Unknown

Assessment of Atherosclerotic Plaque Characteristics Change by DCE-MRI With Alirocumab

Atherosclerosis | Hyperlipidemia

United States
Clinical Operations WCN B.V.
Sanofi

Enrolling by invitation

Comparison of Two Lipid Management Strategies in Very High Risk Patients (PENELOPECTRL)

Atherosclerotic Cardiovascular Disease | STEMI | Non STEMI

Netherlands
Creighton University

Completed

Utility of Clinical Examination in the Noninvasive Prediction of Aortic Atheroma - A Prospective Study

Atherosclerosis

United States
Takeda

Withdrawn

Proof of Mechanism Study of MLN1202 on Atherosclerotic Inflammation in Participants With Stable Atherosclerotic Cardiovascular Disease

Atherosclerotic Cardiovascular Disease
Asan Medical Center
Bayer

Recruiting

Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation (SPIRIT)

Coronary Artery Disease | Peripheral Arterial Disease | Carotid Stenosis | Atherosclerosis of Artery

Korea, Republic of
The University of Hong Kong

Recruiting

Translational Immunodiagnostics in Stroke (TrImS) (TrImS)

Atrial Fibrillation | Acute Ischemic Stroke | Transient Ischemic Attacks | Cardioembolic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis) | Haemorrhagic Stroke | Small Vessel Disease | Stroke of Other Determined Etiology | Stroke of Undetermined Etiology | Stroke of Anterior Cerebral Artery | Stroke... and other conditions

China
Stanford University

Not yet recruiting

Notification of Incidental Coronary Artery Calcium in Patients With Atherosclerotic Cardiovascular Disease (NOTIFY-ASCVD) (NOTIFY-ASCVD)

Coronary Artery Calcification | ASCVD
State Institution "Republican Scientific and Practical...

Recruiting

Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning

Carotid Artery Diseases | Carotid Atherosclerosis | Carotid Artery Stenosis | Cerebral Hyperperfusion Syndrome

Belarus
University of Helsinki
University of Eastern Finland

Completed

The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques

Atherosclerosis

Finland
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Istituti Clinici Scientifici Maugeri SpA
Società Italiana Cardiologia Ospedalità Accreditata (SICOA)

Recruiting

PAtients With Symptomatic Peripheral Artery Disease on Rivaroxaban-acetylsalicylic Acid Combination Therapy (PRO-PAS) (PRO-PAS)

Peripheral Atherosclerotic Disease

Italy
Novartis Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (V-INITIATE)

Atherosclerotic Cardiovascular Disease

United States
Montreal Heart Institute

Completed

Colchicine in Vascular Inflammation Assessed With PET Imaging (COLPET)

Atherosclerotic Vascular Disease

Canada
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Icahn School of Medicine at Mount Sinai
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (CIRT)

Atherosclerotic Cardiovascular Disease | Vascular Inflammation

United States, Canada
National Cerebral and Cardiovascular Center

Unknown

Atheroma Progression and Vulnerability Under Continuous Glucose Monitoring (OPTIMAL)

Coronary Atherosclerosis

Japan
Aristotle University Of Thessaloniki

Completed

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Stroke | Metabolic Syndrome | Type 2 Diabetes | Carotid Atherosclerosis

Greece
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Novo Nordisk A/S

Completed

A Research Study Looking at the Effect of Food Intake on How the Medicine NN0385-0434 Behaves in the Body of Healthy Participants

Healthy Volunteers | Elevated Cholesterol | Established Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD Risk

Germany
Brigham and Women's Hospital

Terminated

The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET Scan

Inflammation | Cardiovascular Disease | Atherosclerosis | Hyperphosphatemia | Dialysis

United States
Massachusetts General Hospital

Completed

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque (BRIGHT-CEA)

Atherosclerosis | Carotid Stenosis | Atherosclerotic Plaque

United States
Universidade do Porto
University of Oxford; University of Edinburgh

Not yet recruiting

Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography (SAFE-CT)

Coronary Artery Disease | Coronary Atheroscleroses

Portugal
Korea University Guro Hospital

Recruiting

Concurrent OCT and FFR-guided PCI in CAD (OPTICARE-CAD)

Coronary Artery Disease | Image | Atheroscleroses, Coronary

Korea, Republic of
Can Tho Stroke International Services Hospital

Completed

Rescue Intracranial Stenting in Acute Ischemic Stroke (RISIS)

Ischemic Stroke | Intracranial Hemorrhages | Stroke, Ischemic | Stent Stenosis | Acute Stroke | Cerebral Ischemia | Intracranial Atherosclerosis | Stent Occlusion | Thrombotic Stroke, Acute

Vietnam
NHS National Waiting Times Centre Board
British Heart Foundation; University of Glasgow; Chief Scientist Office of the...

Recruiting

Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) Trial (CorCMR)

Coronary Artery Disease | Angina, Stable | Angina Pectoris | Microvascular Angina | Non-Obstructive Coronary Atherosclerosis | Small Vessel Cerebrovascular Disease

United Kingdom
Jordan Collaborating Cardiology Group

Terminated

Tracking of Lipid Lowering Therapy in Jordan (JoLLA)

Dyslipidemias | Atherosclerotic Cardiovascular Disease

Jordan
Sheba Medical Center
Carmel Medical Center; University Hospital Goettingen; CVPath Institute Inc.

Unknown

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

Peripheral Vascular Diseases | Atherosclerosis | Aortic Aneurysm

Israel
Diagram B.V.
Isala; St. Jude Medical Nederland B.V.

Completed

Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients (COMBINE)

Coronary Artery Disease | Diabetes Mellitus | Coronary Atheroscleroses

Netherlands
Cedars-Sinai Medical Center
National Institutes of Health (NIH)

Completed

Surgical Indirect Revascularization For Symptomatic Intracranial Arterial Stenosis (ERSIAS)

Ischemic Stroke | Intracranial Atherosclerosis | Intracranial Arterial Stenosis | Cerebral Angiogenesis

United States
China National Center for Cardiovascular Diseases

Not yet recruiting

Natural History of Coronary Atherosclerosis (NASCENT)

Coronary Artery Disease Progression | Optical Coherence Tomography | Atherosclerotic Lesion | Radial Wall Strain
Novartis Pharmaceuticals

Completed

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease (SIRIUS)

Atherosclerotic Cardiovascular Disease

France
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Esperion Therapeutics, Inc.

Completed

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Korea University Guro Hospital

Recruiting

Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability

Inflammation | Atherosclerosis | Acute Coronary Syndrome | Emotional Stress | Atherosclerosis, Coronary | Hematopoiesis | Atherosclerosis Coronary Artery With Angina Pectoris | Atheroma; Heart

Korea, Republic of
Northwell Health

Active, not recruiting

The Young Heart Study

Coronary Artery Disease | Atherosclerotic Cardiovascular Disease

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Universidad de Especialidades Espiritu Santo

Recruiting

Cerebrovascular Correlates of Dementia in Rural Communities - The Three Villages Study

Atherosclerosis | Dementia | Cerebral Small Vessel Diseases | Cognitive Decline | Cardiovascular Risk Factor

Ecuador
Tabba Heart Institute
Getz Pharma

Recruiting

Pakistan Study of Premature Coronary Atherosclerosis in Young Adults (PAKSEHAT)

Stroke | Hypertension | Diabetes Mellitus, Type 2 | Atherosclerotic Plaque

Pakistan
Aristotle University Of Thessaloniki

Unknown

Coronary Artery Geometry and the Severity of Coronary Atherosclerosis (GEOMETRY-CTA)

Coronary Artery Disease | Atherosclerosis | Stable Angina | Atherosclerotic Plaque

Greece
Tongji Hospital

Recruiting

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Ischemic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

China
Ionis Pharmaceuticals, Inc.

Completed

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Hypertriglyceridemia | Atherosclerotic Cardiovascular Disease | Severe Hypertriglyceridemia

United States, Canada
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Canadian Atherosclerosis Imaging Network
Canadian Institutes of Health Research (CIHR)

Completed

Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes

Atherosclerosis

Canada

Clinical Trials on Atherosclerosis, Cerebral

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