Clinical Trials on Autonomic Nervous System Imbalance

Total 84354 results

Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

Non-Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Any Solid Tumor

United States, Japan, Taiwan, Australia, Korea, Republic of, Israel, Spain, Switzerland, Singapore, France, Canada, Italy, Germany, United Kingdom, Hong Kong, Denmark
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Hemoglobinopathies | Hemophagocytic Lymphohistiocytosis | Metabolic Disorders | Primary Immune Deficiency Disorders | Inherited Bone Marrow Failure Syndrome

United States
Sun Yat-sen University

Active, not recruiting

Guangzhou Nutrition and Health Study (GNHS) (GNHS)

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cancer | Chronic Kidney Diseases | Nutrition Disorders | Death | Metabolic Syndrome | Sarcopenia | Osteoporosis | Non-Alcoholic Fatty Liver Disease
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer

Cervical Cancer | Head and Neck Cancer | Esophageal Cancer | Vulvar Cancer | Anal Cancer | Penile Cancer

United States
Gaffree & Guinle Universitary Hospital
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Recruiting

Efficacy of Photobiomodulation in the Rehabilitation of Olfactory Dysfunctions Induced by Long COVID-19

COVID-19 | Rehabilitation | Anosmia | Laser Therapy | Ageusia

Brazil
Hacettepe University

Not yet recruiting

Muscle Architecture in Knee Osteoarthritis

Knee Osteoarthritis | Muscle Weakness | Foot Deformities | Kinesiophobia
San Francisco Veterans Affairs Medical Center

Recruiting

Neural and Cognitive Consequences of COVID-19 Survival

COVID-19 | Fatigue | COVID-19 Pandemic | Concentration Ability Impaired | Memory Deficits | Brain Fog | COVID Long-Haul

United States
RIVER Foundation

Recruiting

RIVER At Home Ketamine Protocols

Chronic Pain | Anxiety Disorders | Chronic Disease | Post Traumatic Stress Disorder | Major Depressive Disorder | Chronic Condition

United States
Marmara University

Not yet recruiting

Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial (IPES)

Sleep-Disordered Breathing | Chronic Thromboembolic Pulmonary Hypertension | Post Operative

Turkey
University Medical Center Groningen

Recruiting

Articulatory Adaptation Following Oral Cancer Treatment (SPOKE)

Speech Disorders | Oral Cavity Squamous Cell Carcinoma

Netherlands
Medical University of South Carolina
National Institutes of Health (NIH); National Institute on Deafness and Other...

Recruiting

Smell Training and Trigeminal Nerve Stimulation for COVID-related Smell Loss

Long COVID | Olfactory Disorder | Smell Dysfunction

United States
University of Stavanger
Stavanger Municipality, Norway

Recruiting

Health Determinants in Older Adults Living at Home

Frailty | Healthy Aging | Alcohol Use, Unspecified | Mental Health Issue | Social Functioning | Vision and Hearing Loss | Cognitive Function, Social 1

Norway
The Third Affiliated hospital of Zhejiang Chinese...

Not yet recruiting

TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer

Non Small Cell Lung Cancer | Bone Metastases | Acupuncture | Cancer Pain
University of Alberta

Recruiting

Nutritional Management of Post COVID-19 Cognitive Symptoms

Long COVID

Canada
Johns Hopkins University
National Institute on Aging (NIA); Labyrinth Devices, LLC

Recruiting

Vestibular Implantation in Older Adults

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity | Presbyvestibulopathy

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Recruiting

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity

United States
Peter Lindenauer, MD
Berkshire Medical Center

Recruiting

Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA

Chronic Obstructive Pulmonary Disease | Angina, Stable | Congestive Heart Failure

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Malignant Neoplasm in the Central Nervous System

United States
University of Copenhagen
Rigshospitalet, Denmark

Recruiting

Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms (PANACEA)

Neoplasms | Quality of Life | Insulin Resistance | Exercise | Body Composition | Sarcopenia | Cachexia | Physical Functional Performance | Muscle, Skeletal | Patient Reported Outcome Measures | Gastrointestinal Microbiome | Metabolism | Caregivers | Adipose Tissue | Proteomics | Mitochondria | Lipidomics | Epigenomics

Denmark
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids (PRESTO)

Pain | Chronic Pain | Sleep Disorder | Sleep | Obstructive Sleep Apnea | Sleep Apnea | Opioid Use | Sleep Disorder; Breathing-Related

United States
Solve ME/CFS Initiative

Recruiting

Solve Together: A Data Collection Platform for the Collection of Patient and Control Health Information to Support Future Research That Will Accelerate Understanding of the Causes of and Possible Treatments for ME/CFS and Other Chronic Diseases, Including Post-viral Illnesses

ME/CFS | Post-Acute COVID-19 Syndrome

United States
Centre Hospitalier National d'Ophtalmologie des...

Recruiting

Bimodal and Coaxial High Resolution Ophtalmic Imaging (AOSLO-OCT)

Stroke | Glaucoma | Hypertension | Diabetes | Retinal Degeneration | Macular Edema | Retinitis Pigmentosa | Retinal Detachment | Vascular Inflammation | Macular Dystrophy | Maculopathy, Age Related

France
Brigham and Women's Hospital
Bristol-Myers Squibb; University of Colorado, Denver; Beth Israel Deaconess Medical... and other collaborators

Recruiting

COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications (CORONA-VTE NET)

Myocardial Infarction | Stroke | Covid19 | Pulmonary Embolism | DVT | Thrombosis Embolism

United States
Peking University First Hospital
Shanghai 10th People's Hospital; Beijing Tsinghua Chang Gung Hospital; Guizhou... and other collaborators

Recruiting

Impact of Remimazolam on Prognosis After Bladder Cancer Surgery

Delirium | Surgery | Bladder Cancer | Benzodiazepines | Cancer Recurrence

China
University of South Florida
Medstar Health Research Institute

Recruiting

Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A

Urinary Bladder, Overactive | Nocturia | Urinary Urge Incontinence | Incontinence, Urinary | Incontinence, Urge | Urinary Frequency More Than Once at Night

United States
Yonsei University

Recruiting

Impact of IntraVascular UltraSound Guidance on the Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study): Retrospective and Prospective Follow-up Study

Myocardial Ischemia(Implanted Drug-eluting Stents Because of Ischemic Heart Disease(Stable Angina, Acute Coronary Syndrome))

Korea, Republic of
Nationwide Children's Hospital
Myonexus Therapeutics

Recruiting

Limb Girdle Muscular Dystrophy Type 2E Recruitment Study

Limb-Girdle Muscular Dystrophy, Type 2E

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

Hypertrophic Cardiomyopathy

United States
Northwestern University

Recruiting

Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Refractory Prostate Cancer | Castration-Resistant Prostatic Cancer

United States
Columbia University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) (NAMDC)

Mitochondrial Diseases | Mitochondrial Disorders | Mitochondrial Genetic Disorders | Disorder of Mitochondrial Respiratory Chain Complexes | Deletion and Duplication of Mitochondrial DNA

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).

Olfactory Neuroblastoma | Esthesioneuroblastoma | Neoplasm of the Nasal Cavity

United States
Guy's and St Thomas' NHS Foundation Trust

Completed

Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation (READ-NIV)

Sleep Disordered Breathing | COPD | Hypercapnic Respiratory Failure | Obesity Hypoventilation Syndrome (OHS)

United Kingdom
Australian Catholic University
Curtin University; Pendulum Therapeutics

Active, not recruiting

OsteoPreP: Food Supplements for Postmenopausal Bone Health (OsteoPreP)

Glucose Metabolism Disorders | Postmenopausal Osteopenia | Age-related Cognitive Decline | Age-Related Sarcopenia | Bone Loss, Age Related

Australia
Deciphera Pharmaceuticals LLC

Active, not recruiting

Study of Vimseltinib for Tenosynovial Giant Cell Tumor (MOTION)

Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse | Tenosynovial Giant Cell Tumor, Localized

Norway, United States, France, Spain, Hong Kong, Netherlands, Italy, Germany, Australia, United Kingdom, Canada, Poland, Switzerland
Auerbach Hematology Oncology Associates P C
AMAG Pharmaceuticals, Inc.

Completed

Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)

Restless Legs Syndrome | Iron Deficiency Anemia

United States
The Hospital for Sick Children

Completed

Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents

Obesity | Central Sleep Apnea | Obstructive Sleep Apnea (Moderate to Severe)

Canada
Rocket Pharmaceuticals Inc.

Completed

Natural History of Danon Disease

Danon Disease

Ireland, Czechia, France, Italy, Spain
Boston Urogynecology Associates

Completed

Minimizing Pain During Office Intradetrussor Botox Injection

Overactive Bladder | Overactive Detrusor | Urge Incontinence | Overactive Bladder Syndrome | Overactivity; Behavior

United States
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
University of Oxford
Mount Sinai Hospital, Canada

Completed

Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit (SAnDMAN)

Critical Illness | Covid19 | Analgesia | Sedation Complication | Intensive Care Unit Delirium

United Kingdom
University of Miami
The Gerber Foundation

Completed

Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants

Apnea of Prematurity | Periodic Breathing | Desaturation of Blood | Central Apnea | Obstructive Apnea of Newborn

United States
Assistance Publique - Hôpitaux de Paris

Completed

Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease (MARFANLOMB)

Marfan Syndrome

France
Hospices Civils de Lyon

Terminated

Sleep Apnea in Sickle Cell Disease (DREPAPNEE)

Sickle Cell Disease

France
Zhuan Zhang

Completed

Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis

Peripheral Facial Palsy

China
National Research Centre for the Working Environment...
TrygFonden, Denmark; Aalborg University; Team Arbejdsliv; Statistics Denmark

Active, not recruiting

SeniorWorkingLife (Danish Title: SeniorArbejdsLiv) (SAL2018)

Musculoskeletal Pain | Occupational Exposure | Occupation-related Stress Disorder | Work-Related Stress Disorder | Work Accident | Work Injury | Work Related Upper Limb Disorder

Denmark
University of Louisville

Withdrawn

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Pelvic Organ Prolapse | Surgery | Narcotic Use | Post Operative Pain Control | Urinary Incontinence , Stress

United States
University Hospital, Strasbourg, France

Terminated

Predictive Factors of Obesity-hypoventilation Syndrome (OHS) Among Obese Subjects- ETUDE COHYPOB -

Obesity-hypoventilation Syndrome | Nocturnal Alveolar Hypoventilation

France
Johns Hopkins University

Completed

Ketogenic Diet for Obesity Hypoventilation Syndrome (KETOHS)

Hypercapnic Respiratory Failure | Obesity Hypoventilation Syndrome | Ketogenic Dieting

United States

Clinical Trials on Autonomic Nervous System Imbalance

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