Clinical Trials on Bacteremia Sepsis in South Africa

Total 92 results

The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
National Institute of Allergy and Infectious Diseases...

Completed

DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia

Staphylococcal Bacteraemia

United States, Canada
Spectral Diagnostics (US) Inc.

Recruiting

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Septic Shock | Endotoxemia

United States
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
MicroPhage, Inc.

Terminated

Study of the Performance of the KeyPath MRSA/MSSA Blood Culture Test - BTA

Bacteremia

United States
University of Stellenbosch
Fogarty International Center of the National Institute of Health

Unknown

Neonatal Bacterial Colonization Study

Prematurity | Bloodstream Infection | Neonatal SEPSIS | Very Low Birth Weight Baby

South Africa
Murdoch Childrens Research Institute
University of Otago; Sydney Children's Hospitals Network; Royal Children's Hospital and other collaborators

Completed

Improving Dosing of Vancomycin in Young Infants With Infections (VANCAPP)

Sepsis | Bacteremia | Infection

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Royal Hospital For Women

Completed

RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates

Sepsis | Bacteremia | Infection

Australia
University of Melbourne
Radboud University Medical Center; Sunnybrook Health Sciences Centre; UMC Utrecht and other collaborators

Recruiting

Staphylococcus Aureus Network Adaptive Platform Trial (SNAP)

Staphylococcus Aureus Bacteremia

Australia, New Zealand, Canada, Singapore, Netherlands, Israel
University of KwaZulu
Bristol-Myers Squibb

Completed

Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women

Puerperal Sepsis

South Africa
Forest Laboratories

Completed

Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia | Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia

United States
Merit Medical Systems, Inc.
Integra Clinical Trial Solutions - statistical analysis; Ross, John, M.D.

Completed

HeRO Vascular Access Device Bacteremia Study

Hemodialysis

United States
Basilea Pharmaceutica
Department of Health and Human Services

Completed

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia

Israel, United States, Georgia, Russian Federation, Ukraine, Colombia, Argentina, Bulgaria, Germany, Greece, Italy, Mexico, Panama, Serbia, South Africa, Spain, Turkey
University of Athens

Recruiting

Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (CORVICTES-ΥΜ)

Septic Shock

Greece
University of Witwatersrand, South Africa

Terminated

Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum

Stasis Ulcer

South Africa
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
University of Athens
Naval Hospital, Athens; General Hospital of Nikaia "Saint Panteleimon"

Recruiting

Vitamin C, Hydrocortisone and Thiamine for Septic Shock (CORVICTES)

Shock, Septic

Greece
Duke University
National Institutes of Health (NIH)

Completed

Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection (Bacteremia)

Bacteremia

United States, Spain
The George Institute for Global Health, Australia

Completed

Days Alive and Out of Hospital for Patients With Sepsis

Sepsis | Septic Shock

Australia
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
The George Institute

Completed

Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS (FluDReSS)

Septic Shock | Critically Ill

Australia
The George Institute
National Health and Medical Research Council, Australia; Australian and New...

Completed

ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (ADRENAL)

Septic Shock

Australia, Denmark, Saudi Arabia, New Zealand, United Kingdom
Drugs for Neglected Diseases
Universiteit Antwerpen; PENTA Foundation; St George's, University of London

Completed

NeoAMR Observational Study in Neonatal Sepsis

Neonatal SEPSIS

Bangladesh, Uganda, Thailand, South Africa, Italy, Greece, India, Brazil, China, Kenya, Vietnam
Sunnybrook Health Sciences Centre

Completed

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE)

Sepsis | Mortality | Bacteremia | Critically Ill | Intensive Care | Antimicrobial

New Zealand, United States, Canada, Australia, Switzerland, Saudi Arabia, Israel
Pfizer

Terminated

Colombia Epidemiologic Surveillance Study (LEAP II)

Pneumonia | Sepsis | Bacteremia | Meningitis

Colombia, Brazil, Costa Rica
Australian and New Zealand Intensive Care Research...

Recruiting

Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis (ARISE FLUIDS)

Shock, Septic

Australia
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
Universitas Sriwijaya
Indonesia University

Completed

Resuscitation Failure, Oxidative Stress, and Necroptosis as Mortality Predictor in Septic Patient

Sepsis

Indonesia
PMD Solutions
Hospital of South West Jutland

Completed

Can Respiratory Rate Predict the Risk of Deterioration of Septic Patients

Sepsis

Denmark
Cardiff and Vale University Health Board
Cardiff University

Recruiting

nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis (nSeP)

Sepsis

United Kingdom
Massachusetts General Hospital

Completed

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS)

Septic Shock

United States
Scynexis, Inc.

Completed

Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) (CARES)

Candidemia | Candidiasis, Invasive

Pakistan, India, United States, South Africa
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
Astellas Pharma Inc

Completed

Study of Mycamine® in Children With Fungal Infections to Evaluate Safety and Blood Levels of the Drug

Candidemia | Invasive Candidiasis | Esophageal Candidiasis | Oropharyngeal Candidiasis

United States, South Africa
Belinda Howe
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian...

Unknown

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

Severe Sepsis

New Zealand, Australia, Finland, Ireland, Hong Kong
University of Virginia
National Institutes of Health (NIH); Medical Predictive Science Corporation

Completed

Impact of Heart Rate Characteristics Monitoring in Neonates (HeRO)

Sepsis

United States
Medical University of South Carolina
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Critical Care Excellence in Sepsis and Trauma (CREST)

Sepsis | Trauma

United States
Eisai Inc.

Completed

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Severe Sepsis

United States, France, Poland, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Switzerland, Argentina, Belgium, Israel, South Africa, Japan, Canada, Netherlands, Korea, Republic of, Australia, Chile, Brazil, Austria, Italy, Czechia, Portug...
The University of Queensland

Completed

Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response (MERINO II)

Bloodstream Infections

Singapore, Australia
Eli Lilly and Company

Completed

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Severe Sepsis

United States, Belgium, Spain, France, Finland, Germany, Canada, United Kingdom, Puerto Rico
South West Sydney Local Health District

Recruiting

Capnodynamic Monitoring of Cardiorespiratory Function in Critically Ill Patients (PROFICIENT)

Sepsis | Acute Respiratory Infection | Postoperative Respiratory Distress

Australia
Nationwide Children's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS (GRACE-2)

Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome

United States
University of Adelaide

Completed

The Long-term Impact of Invasive Meningococcal Disease in Australian Adolescents and Young Adults (AMEND)

Meningococcal Infections | Neisseria Infection | Neisseria Meningitis Sepsis

Australia
The University of Queensland

Recruiting

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients (BEAT-BK)

Kidney Transplant Infection | Kidney Transplant Failure and Rejection | BK Viremia

Australia

Clinical Trials on Bacteremia Sepsis in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations