Clinical Trials on Blood Component Transfusion

Total 94163 results

Shire

Terminated

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Beta-Thalassemia | Transfusional Iron Overload

United States, Lebanon, Canada, Italy, Turkey
Shire

Completed

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, United Kingdom, Italy, Thailand, Turkey
FerroKin BioSciences, Inc.

Completed

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, Australia, Thailand
Novartis Pharmaceuticals

Completed

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload in β-thalassemia

United States, Greece, Argentina, Germany, Belgium, Italy, United Kingdom, France, Tunisia, Canada, Turkey, Brazil
Novartis Pharmaceuticals

Completed

Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload | β-thalassemia

Italy
Bloodworks
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prospective Study of HIV Infection in Hemophiliacs

HIV Infections | Acquired Immunodeficiency Syndrome | Hemophilia A | Hepatitis, Viral, Human | Blood Disease | Cytomegalovirus Infections | Blood Transfusion
Children's Hospital of Philadelphia
Ann & Robert H Lurie Children's Hospital of Chicago; The Cooley's Anemia Foundation...

Completed

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Thalassemia Major With Severe Transfusional Iron Overload

United States
Medical College of Wisconsin
National Heart, Lung, and Blood Institute (NHLBI); University of Wisconsin,... and other collaborators

Recruiting

Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Sudden Infant Death | Congenital Heart Disease | Pregnancy Loss | Gastroschisis | Fetal Death | Brugada Syndrome | High Risk Pregnancy | Stillbirth | Long QT Syndrome | Fetal Demise | Birth Defect | Twin Monochorionic Monoamniotic Placenta | Twin Twin Transfusion Syndrome | Fetal Hydrops | Fetal Arrhythmia | Intrauterine... and other conditions

United States
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer

Stage IA Breast Cancer | Stage IB Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-positive Breast Cancer | Invasive Ductal Breast Carcinoma | Medullary Ductal Breast Carcinoma With Lymphocytic Infiltrate | Mucinous Ductal Breast Carcinoma | Papillary Ductal Breast... and other conditions

United States
Novartis Pharmaceuticals

Completed

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Transfusional Iron Overload | β-thalassemia Major | Pediatric Rare Anemia

Italy, France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrovirus Epidemiology Donor Study-II (REDS-II)

HIV Infections | Acquired Immunodeficiency Syndrome | Retroviridae Infections | Hepatitis B | Hepatitis, Viral, Human | Blood Transfusion | HIV-1 | Blood Donors | Hepacivirus | HIV-2 | HTLV-I | HTLV-II | West Nile Virus
Novartis Pharmaceuticals

Completed

Observation of Patients With Transfusional Hemosiderosis Treatment With Deferasirox

Transfusional Hemosiderosis

Egypt, Spain, United Kingdom, Jordan
Novartis Pharmaceuticals

Completed

Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food

Transfusional Hemosiderosis

United States
Millennium Pharmaceuticals, Inc.

Completed

Study of Alisertib (MLN8237) in Adults With Aggressive Non-Hodgkin's Lymphoma

Mantle Cell Lymphoma | Diffuse Large B-cell Lymphoma | Burkitt's Lymphoma | T-cell Lymphoma, Excluding Primary Cutaneous T-cell Lymphoma | Transformed Follicular Lymphoma With ≥ 50% Diffuse Large Cell Component

United States
Talaris Therapeutics Inc.
Duke University

Withdrawn

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Anemia, Sickle Cell | Thalassemia | Beta-Thalassemia | Bone Marrow Failure Syndromes | Diamond-Blackfan Anemia | Alpha-Thalassemia | Complex and Transfusion-dependent Hemoglobinopathies

United States
Columbia University

Completed

High-Tc Susceptometer to Monitor Transfusional Iron Overload

Myelodysplastic Syndromes | Sickle Cell Disease | Aplastic Anemia | Transfusional Iron Overload | Thalassemia Major

United States
Novartis Pharmaceuticals

Completed

An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)

Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia

Australia
Masonic Cancer Center, University of Minnesota

Recruiting

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Sickle Cell Disease | Severe Congenital Neutropenia | Paroxysmal Nocturnal Hemoglobinuria | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Diamond Blackfan Anemia | Transfusion Dependent Alpha- or Beta- Thalassemia | Non-Malignant Hematologic Disorders

United States
Novartis

Completed

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

Myelodysplastic Syndromes | Hemoglobinopathies | Diamond-Blackfan Anemia | Transfusional Iron Overload | Other Inherited or Acquired Anaemia | MPD Syndrome | Other Rare Anaemias

Australia
University Hospital, Linkoeping

Completed

Volume Kinetics for Starch Solution and Acetated Ringers

Blood Coagulation | Blood Volume

Sweden
University of New Mexico
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Blood Donation--Immune Sequelae and Recruitment

Blood Disease | Blood Donors
SE Health
Centre for Aging and Brain Health Innovation

Completed

MediBeat - HeartBeat Observation Trial

Hypertension | Blood Pressure | Hypotension | High Blood Pressure | Low Blood Pressure

Canada
Azienda Ospedaliera San Giovanni Battista

Unknown

Efficacy of Biosimilar Filgrastim on the Mobilization of Hematopoietic Stem Cell CD34+ (Cluster of Differentiation 34) and on the Kinetic Engraftment

Blood Diseases

Italy
ROX Medical, Inc.

Completed

Registry to Evaluate the ROX COUPLER in Patients With Resistant or Uncontrolled Hypertension

Hypertension | Blood Pressure, High | Blood Pressure, Resistant | Blood Pressure, Uncontrolled

United Kingdom, Netherlands, Belgium
DongGuk University

Active, not recruiting

The Effect of Home Blood Pressure Measurement on the Management of Hypertension

Hypertension | Blood Pressure | Ambulatory Blood Pressure | Home Blood Pressure Measurement

Korea, Republic of
Inland Norway University of Applied Sciences
University of Oslo

Completed

Daily Physical Activity After Meals -Long Term Effects on Blood Glucose

Blood Glucose | Blood Glucose Related Variables

Norway
Globe Biotech Limited

Completed

A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002

Natural Blood and Blood Product Toxicity

Bangladesh
Wageningen University and Research

Completed

The Effect of Chewing Duration on Blood Glucose Levels

Glucose, Low Blood | Glucose, High Blood

Netherlands
Henry Ford Health System

Completed

Oral and Intravenous Tranexamic Acid in Lumbar Spine Surgery

Blood Loss, Surgical | Blood Loss Anemia

United States
Assiut University

Completed

Effects of Terlipressin on Blood Loss and Transfusion Requirements During Major Liver Resection.

Hepatectomy, Surgical Blood Loss, Terlipressin

Egypt
Ingredion Incorporated
KGK Science Inc.

Completed

Post-prandial Glycemic Response to Fiber in Healthy Adults

Glucose, Low Blood | Glucose, High Blood | Meals
The University of Texas Health Science Center at...

Recruiting

Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy

Myomectomy; Surgical Blood Loss

United States
Catharina Ziekenhuis Eindhoven

Completed

Platelet Function in Minimal Extracorporeal Circulation in CABG (ECCTEG)

Thrombocytopathy

Netherlands
SuxiaLuo

Recruiting

A Real-world Study of Herombopag in the Treatment of Thrombocytopenia Related Diseases in Henan Province

Carcinoma;Blood

China
Heinrich-Heine University, Duesseldorf

Completed

Red Blood Cells as a Reflection of Endothelial Function in Old Age

Endothelial Function | Red Blood Cells | Nitric Oxide Pool in Red Blood Cells and Blood Plasma

Germany
Dow University of Health Sciences

Completed

Health Effect of Energy Drink Consumption

Cognitive Change | Blood Pressure | Blood Glucose, High

Pakistan
Tanta University

Completed

Laparoscopic Splenectomy in Children (splenectomy)

Children | Laparoscopic Splenectomy | Benign Blood Diseases
Istituto Auxologico Italiano

Recruiting

Novel BP Monitoring Methods to Study the Association Between Sleep BP Patterns and BP Values in Daily Life (CABER-NET)

Arterial Hypertension | Ambulatory Blood Pressure Monitoring | Blood Pressure Determination | Home Blood Pressure Monitoring

Italy
Imperial College Healthcare NHS Trust

Completed

Pre-conception Interventions to Reduce Blood Pressure Before Pregnancy (CONCEIVE 2)

Blood Pressure

United Kingdom
Medstar Health Research Institute

Terminated

Renal Denervation in Patients With Uncontrolled Blood Pressure

Blood Pressure

United States
University of Helsinki
Fazer Group

Completed

The Effects of Dark Chocolate on Blood Pressure in Individuals With Mildly Elevated Blood Pressure (CHOKO)

Blood Pressure

Finland
Vidacare Corporation

Unknown

Infusion Flow Rates and Blood Sampling

Intraosseous Access | Infusion Rates | Intraosseous Blood | Venous Blood

United States
Duke University
American Heart Association

Completed

Mechanism of the Blood Pressure Lowering Effect of the DASH Dietary Pattern

Blood Pressure
The University of The West Indies

Completed

The Effect of Cocoa on Platelet Function Profiles in Patients (ECLAIR)

Platelet Dysfunction

Trinidad and Tobago
Fundación para la Formación e Investigación de...
Instituto de Salud Carlos III

Not yet recruiting

Automated Measurement of Blood Pressure in Waiting Room (AMBP-waiting) (AMBP-waiting)

Hypertension | Blood Pressure Measurement | Blood Pressure
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Collection of Peripheral Blood Mononuclear Cells From Healthy Subjects

Disease of the Blood
Assiut University

Not yet recruiting

Effect of Storage Condition on CD47 Expression Level in Platelet Concentrate

Platelet Storage Pool Deficiency
University Hospital, Brest

Completed

Comparison of Two D-Dimers Dosing Techniques (COMPADDI)

Blood Coagulation Disorder

France
Turku University Hospital
Helsinki University Central Hospital

Completed

NOAC Plasma Concentration and Blood Coagulation in Healthy Volunteers (EdoRot)

Blood Coagulation Disorder

Finland
Swanson Center

Completed

Sequential Compression Devices Effect on Fibrinolysis in Plastic Surgery Outpatients

Blood Coagulation Disorder

United States

Clinical Trials on Blood Component Transfusion

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