Clinical Trials on Blood Donor

Total 94848 results

Alison Walker
Novartis; Millennium Pharmaceuticals, Inc.

Completed

Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid... and other conditions

United States
University of Aarhus

Completed

Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome

Marfan Syndrome | Bicuspid Aortic Valve | Turner Syndrome

Denmark
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Anaplastic Large Cell Lymphoma

United States
National Taiwan University Hospital
National Cheng-Kung University Hospital

Unknown

Mitochondrial nt3243 A>G Mutation in Taiwan

MELAS Syndrome | Noninsulin-dependent Diabetes Mellitus With Deafness

Taiwan
National Cancer Institute (NCI)

Completed

A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS)

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
University of Alabama at Birmingham

Terminated

Lenalidomide Therapy for Patients With Relapsed and/or Refractory, Peripheral T-Cell Lymphomas

Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Peripheral T-cell Lymphomas | Adult T-cell Leukemia | Adult T-cell Lymphoma | Peripheral T-cell Lymphoma Unspecified | T/Null Cell Systemic Type | Cutaneous t-Cell Lymphoma With Nodal/Visceral Disease

United States
Mayo Clinic

Completed

Predictive Genetic Risk Assessment Trial (PGT)

Myocardial Infarction | Obesity | Breast Cancer | Osteoarthritis | Atrial Fibrillation | Graves Disease | Lung Cancer | Celiac Disease | Prostate Cancer | Colon Cancer | Diabetes Type 2

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Testicular Germ Cell Tumor | Breast Cancer | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma

United States
Tel-Aviv Sourasky Medical Center

Unknown

11C-Acetate PET/CT Non-FDG-Avid Tumors

Carcinoma, Hepatocellular | Lung Cancer | Neuroendocrine Tumors | Thyroid Cancer | Carcinoma, Lobular | Teratoma | GIST | Soft Tissue Sarcomas | Indolent Lymphoma | Uterine Malignancies

Israel
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis

Stroke | Pain | Multiple Sclerosis | Chronic Pain | Traumatic Brain Injury | Neuropathic Pain | Pain, Chronic | Chronic Pain Syndrome | Paraplegia | Phantom Pain | Pain Syndrome | Central Neuropathic Pain | Phantom Limb Syndrome With Pain

Germany
Scripps Translational Science Institute

Recruiting

The Long COVID-19 Wearable Device Study

Chronic Fatigue Syndrome | Postural Orthostatic Tachycardia Syndrome | Dysautonomia | Long COVID | Long Covid19 | Myalgic Encephalomyelitis

United States
University Hospital Inselspital, Berne

Recruiting

Prognosis of Cerebral Small Vessel Disease - a Prospective Cohort Study (PRO-SVD)

Cerebral Amyloid Angiopathy | Cadasil | Small Vessel Cerebrovascular Disease | CAA - Cerebral Amyloid Angiopathy

Switzerland
H. Lee Moffitt Cancer Center and Research Institute
Precigen, Inc

Recruiting

Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies

Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B Cell Lymphoma | Triple Negative Breast Cancer Malignancies

United States
Eurasian Association of Therapists

Recruiting

Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease (AURA)

COVID-19 | Hypertension | Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Atrial Fibrillation | PreDiabetes | Ischemic Heart Disease | Chronic Heart Failure | Urolithiasis

Russian Federation
Totus Medicines

Recruiting

A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With Select Solid Tumors

Cervical Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Squamous Cell Carcinoma of Head and Neck | Endometrial Cancer | Non-small Cell Lung Cancer | Urothelial Carcinoma | HER2-negative Breast Cancer

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Lymphoma | Multicentric Castleman Disease | Plasmablastic Lymphoma | Kaposi Sarcoma | Recurrent Lymphoma | Anal Carcinoma | Recurrent Kaposi Sarcoma | Recurrent Plasmablastic Lymphoma | Transplant-Related Kaposi Sarcoma

United States
Monte Rosa Therapeutics, Inc

Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast Cancer

United States, Canada
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

HIV Infections | Cancer | HPV-Related Malignancy | Anal Cancer | HIV-Associated Malignant Neoplasm | AIDS Related Lymphoma | AIDS-related Kaposi Sarcoma | AIDS-Related Malignancy

United States
Centre Leon Berard
Novartis; Roche Pharma AG; Fondation Apicil; Malakoff-Humanis; Fédération Leucémie... and other collaborators

Recruiting

A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. (PASCA)

Acute Myeloid Leukemia | Hodgkin Disease | Osteosarcoma | Non Hodgkin Lymphoma | Late Effects | Ewing's Sarcoma | Testicular Germ Cell Tumor Mixed | Non-Metastatic Breast Carcinoma | Soft Tissue Sarcoma, Adult, Stage IIC

France
Hjalmar Bouma

Recruiting

Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine (Acutelines)

Pneumonia | Sepsis | Shock | Hemorrhage | Emergencies | Thrombosis | Frailty | Syncope | Urinary Tract Infections | Acute Kidney Injury | Acute Disease | Pulmonary Embolism | Dyspnea | Anaphylaxis | Polypharmacy | Complication of Treatment | Electrolyte Disturbance | Skin Infection | Intoxication by Drug

Netherlands
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic Syndrome | Refractory Mixed Phenotype Acute Leukemia | Refractory Acute Leukemia... and other conditions

United States
Medical College of Wisconsin

Recruiting

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Follicular Lymphoma | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Chronic Lymphocytic Leukemia (CLL) | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Central Nervous System Lymphoma | Mantle Cell Lymphoma (MCL) | Non Hodgkin Lymphoma (NHL)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

Sezary Syndrome | Recurrent Mycosis Fungoides | Refractory Mycosis Fungoides | Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma | Folliculotropic Mycosis Fungoides | Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified | Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma | Refractory Cutaneous...

United States
Leigh R. Hochberg, MD, PhD.
National Institute of Neurological Disorders and Stroke (NINDS); US Department... and other collaborators

Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2)

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injuries | Tetraplegia | Brain Stem Infarctions | Locked in Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | High Risk Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 | Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Acute Myeloid... and other conditions

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Evaluation of Patients With Immune Function Abnormalities

Chronic Granulomatous Disease (CGD) | X-Linked Severe Combined Immune Deficiency (XSCID) | Leukocyte Adhesion Deficiency 1 (LAD) | Graft Versus Host Disease (cGvHD)

United States
Ohio State University Comprehensive Cancer Center
MorphoSys AG

Active, not recruiting

Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL

Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Contiguous Stage II Small Lymphocytic... and other conditions

United States
Sanliurfa Mehmet Akif Inan Education and Research...

Completed

Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients

Depressive Disorder | Restless Legs Syndrome | Anemia of Chronic Kidney Disease | Hemodialysis-Associated Pruritus | Malnutrition-Inflammation-Cachexia Syndrome

Turkey
Hospices Civils de Lyon

Completed

Evaluation of Ultra-portable Ultrasound in General Practice (EPEMedG)

Pneumonia | Renal Colic | Phlebitis | Pleural Effusion | Hepatic Colic or Cholecystitis | Subcutaneous Abscess or Cyst | Fracture of Long Bones | Intra-uterine Pregnancy or Extra-uterine Pregnancy or Miscarriage

France
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Hemoglobinopathies | Hemophagocytic Lymphohistiocytosis | Metabolic Disorders | Primary Immune Deficiency Disorders | Inherited Bone Marrow Failure Syndrome

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma

HIV Infection | AIDS-Related Diffuse Large B-cell Lymphoma | AIDS-Related Primary Effusion Lymphoma | AIDS-Related Burkitt Lymphoma | AIDS-Related Plasmablastic Lymphoma | AIDS Related Non-Hodgkin Lymphoma

United States
Merck Sharp & Dohme LLC

Terminated

To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Anemia | Bladder Cancer | Cancer of Head and Neck | Uterine Cervical Cancer | Carcinoma, Small-Cell Lung
Ohio State University Comprehensive Cancer Center

Completed

Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Recurrent Lung Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Caregiver | Metastatic Thymic Carcinoma | Malignant Pleural... and other conditions

United States
University of Alabama at Birmingham
Lakeshore Foundation; YMCA of Greater Birmingham

Active, not recruiting

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study (M2M LEADERS)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Traumatic Brain Injury | Spinal Cord Injuries | Spina Bifida

United States
AVM Biotechnology Inc

Available

Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

Cancer | Breast Cancer | Glioblastoma | Gastric Cancer | Pancreatic Cancer | Hodgkin Lymphoma | Ovarian Cancer | Prostate Cancer | Acute Leukemia | Non-hodgkin Lymphoma | Squamous Cell Carcinoma | Tumor, Solid | Tumor, Brain | Spindle Cell Sarcoma
Casa Colina Hospital and Centers for Healthcare
UCLA Department of Psychology; Tiny Blue Dot INC.

Completed

The Use of LIFUP in Chronic Disorders of Consciousness

Traumatic Brain Injury | Disorder of Consciousness | CVA (Cerebrovascular Accident) | Minimally Conscious State | Vegetative State | Thalamic Infarction | Coma; Prolonged | Minimally Conscious State Plus | Minimally Conscious State Minus | Anoxia, Brain

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | B-cell Adult Acute Lymphoblastic Leukemia | Acute Leukemias of Ambiguous Lineage | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia

United States
Mandos LLC

Completed

VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, France, New Zealand, Singapore, Spain, Turkey
Elizabeth Glaser Pediatric AIDS Foundation
Bill and Melinda Gates Foundation

Active, not recruiting

Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi

AIDS-related Kaposi Sarcoma | Cryptococcal Infections | AIDS and Infections | Opportunistic Infections, HIV-Related | AIDS With Tuberculosis

Malawi
Sun Yat-sen University

Active, not recruiting

Guangzhou Nutrition and Health Study (GNHS) (GNHS)

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cancer | Chronic Kidney Diseases | Nutrition Disorders | Death | Metabolic Syndrome | Sarcopenia | Osteoporosis | Non-Alcoholic Fatty Liver Disease
East Kent Hospitals University NHS Foundation Trust
KU Leuven; University of Kent; Sussex Community NHS Foundation Trust; l'Institut...

Completed

An Assistive Powered Wheelchair: Stage 2 Trial (EDUCAT)

Stroke | Multiple Sclerosis | Craniocerebral Trauma | Cystic Fibrosis | Guillain-Barre Syndrome | Motor Neurone Disease

United Kingdom
NHS Blood and Transplant
Irish Blood Transfusion Service; Welsh Blood Service; Scottish National Blood...

Completed

Notification of Donors With Positive Microbiology Markers

Hepatitis B | Hepatitis C | Human Immunodeficiency Virus | Creutzfeldt-Jakob Syndrome | Human T-lymphotropic Virus I & II

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa
NMC Specialty Hospital

Completed

Practice Variation on Antithrombotics in COVID-19

Thrombosis | COVID-19 Pneumonia | Severe Acute Respiratory Syndrome (SARS) Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

India
LMC Diabetes & Endocrinology Ltd.

Completed

Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population (PEDAL)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Onychomycosis | Foot Deformities | Neuropathy, Diabetic | Foot Ulcer, Diabetic | Hyperkeratosis | Onychauxis

Canada
Massachusetts General Hospital
Genzyme, a Sanofi Company; Scott and White Hospital & Clinic

Terminated

Kidney Information Network for Disease Research and Education (KINDRED)

Kidney Diseases | Genetic Diseases, X-Linked | End Stage Renal Disease | ESRD | Fabry Disease | Rare Diseases

United States
Shandong Provincial Hospital

Unknown

CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL

Hepatosplenic T-cell Lymphoma | Peripheral T-Cell Lymphoma, Not Otherwise Specified | ALK-negative Anaplastic Large Cell Lymphoma | Angioimmunoblastic T Cell Lymphoma | Enteropathy Associated T Cell Lymphoma | Subcutaneous Panniculitis Like T Cell Lymphoma

China
Acrotech Biopharma Inc.
National Cancer Institute (NCI)

Completed

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Sarcoma | Lymphoma | Leukemia | Neuroblastoma | Brain Tumors | Wilms Tumor

United States
Robert Lowsky
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Intratumoral Injection of SD-101

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic...

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Intraocular Lymphoma | Central Nervous System Lymphoma | B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma | Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System and other conditions

United States

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