Clinical Trials on Bone Neoplasms in South Africa

Total 7646 results

Johns Hopkins University
National Institute of Mental Health (NIMH); University of Witwatersrand, South...

Completed

Home Link: Post Hospital Care to Reduce HIV Mortality in South Africa (HomeLink)

HIV/AIDS

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

Comparison of DTaP-IPV-Hep B-PRP~T Combined Vaccine to CombAct-HIB® Concomitantly Given With Engerix B® Paediatric and OPV

Hepatitis B | Pertussis | Diphtheria | Polio | Haemophilus Influenzae Type b

South Africa
Centre for the AIDS Programme of Research in South...
ViiV Healthcare

Withdrawn

Safety and Acceptability of Cabotegravir in HIV Uninfected Women in KwaZulu-Natal, South Africa (CAPRISA014)

Human Immunodeficiency Virus

South Africa
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
BioCryst Pharmaceuticals

Terminated

A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria | PNH

United Kingdom, Austria, South Africa
Centre for the AIDS Programme of Research in South...
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Active, not recruiting

INSTI's For The Management of HIV-associated TB (INSIGHT)

HIV/AIDS | Tuberculosis, Pulmonary

South Africa
University of Stellenbosch
Thrasher Research Fund

Unknown

The Effect of Bacille Calmette Guerin (BCG) Vaccination on Immune Responses in HIV-Exposed and Unexposed Infants

HIV Infections

South Africa
University of KwaZulu

Completed

Isolated Vascularized Gastric Tube Biliary Enteric Drainage: A Paediatric Case Series Experience.

Biliary Obstruction | Choledochal Cyst

South Africa
Boehringer Ingelheim

Completed

Trial to Evaluate Steady State Pharmacokinetic Parameters, Efficacy and Safety of Nevirapine in Antiretroviral Drug naïve Pediatric Patients

HIV Infections

South Africa
ApoPharma

Completed

Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects

Asymptomatic HIV Infection

South Africa
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - Dir. Gen. for Cooperation and Development

Completed

Study to Assess the Seroprevalence of Anti-Tat Antibodies in HIV-infected Patients (ISS OBS T-004)

HIV Infection

South Africa
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in First Line in Patients With Metastatic Colorectal Cancer (AVANiS)

Colorectal Cancer

South Africa
BioCryst Pharmaceuticals

Terminated

BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy (REDEEM-2)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Malaysia, South Africa, Korea, Republic of
Brown University
Rhode Island Hospital; University of Cape Town; Medical Research Council, South... and other collaborators

Active, not recruiting

Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

Depression | Sexually Transmitted Diseases | Human Immunodeficiency Virus

South Africa
University of Washington
Harvard Medical School (HMS and HSDM); National Institute of Mental Health... and other collaborators

Completed

The Prevention Options for Women Evaluation Research (POWER) Cohort

HIV/AIDS

Kenya, South Africa
Population Council
United States Agency for International Development (USAID); Bill and Melinda...

Completed

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

HIV Infections | Sexually Transmitted Diseases | AIDS | HIV Seroconversion

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
Takeda

Completed

Effect of Dexlansoprazole on Bone Homeostasis

Bone and Bones | Homeostasis

United States
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
GlaxoSmithKline

Completed

Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth

Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis

South Africa
University of Stellenbosch

Unknown

The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

Haemoptysis

South Africa
Boston University Charles River Campus
Massachusetts General Hospital; University of Witwatersrand, South Africa

Not yet recruiting

Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2

Cervical Cancer | Hiv

United States, South Africa
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults (HVTN 097)

HIV Infection

South Africa
FHI 360
United States Agency for International Development (USAID); Makerere University and other collaborators

Completed

Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs)

HIV Infections | HIV/AIDS

South Africa, Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084

HIV Infections

Zimbabwe, South Africa, Uganda
Massachusetts General Hospital
National Institute of Mental Health (NIMH); Match Research

Completed

Support for Perinatal Adherence and Depression (INSPireD)

Depression | Human Immunodeficiency Virus

United States, South Africa
Boehringer Ingelheim

Completed

A Study of Single Dose Nevirapine (NVP) Combined With Combivir® for the Prevention of Mother to Child Transmission (pMTCT) - Treatment Options Preservation Study (TOPS)

Acquired Immunodeficiency Syndrome

South Africa
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
Hoffmann-La Roche

Completed

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Malignant Melanoma

South Africa
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
University of Cape Town

Completed

Iron Deficiency Anaemia in Pregnant Patients Presenting for Antenatal Care

Iron Deficiency Anemia of Pregnancy

South Africa
Novartis Pharmaceuticals

Completed

1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids

Osteoporosis

Australia, Canada, Russian Federation, Hungary, South Africa, United Kingdom
International Partnership for Microbicides, Inc.

Completed

A Safety and Tolerability Study of Dapivirine (TMC120) Vaginal Microbicide Gel

HIV Infections

Rwanda, South Africa, Tanzania
McMaster University
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS); The Physicians' Services Incorporated Foundation and other collaborators

Completed

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) (PARITY)

Bone Neoplasms | Infection

United States, Canada, Netherlands, Australia, Spain, Singapore, Brazil, India, Argentina, Austria, South Africa, Egypt
GlaxoSmithKline
University of Cape Town; African Organization for Research and Training in...

Completed

Type Distribution of Human Papillomavirus in Adult African Women Diagnosed With Invasive Cervical Cancer

Cervical Cancer | Infections, Papillomavirus

Ghana, Nigeria, South Africa
Cynthia S Firnhaber
Merck Sharp & Dohme LLC

Completed

A Study to Examine the Human Papillomavirus Types Exposure in Women From Southern Africa and Brasil

HIV Infections | HIV

Botswana, Brazil, South Africa
University of California, San Francisco
Bill and Melinda Gates Foundation; Medical Research Council, South Africa; Ibis... and other collaborators

Withdrawn

Effectiveness of the Diaphragm for HIV Prevention

HIV Infection

South Africa, Zimbabwe
GlaxoSmithKline

Completed

Parkinson's Disease Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole

Parkinson Disease

Germany, South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants (HVTN139)

HIV Infections

South Africa
French National Agency for Research on AIDS and...
Gilead Sciences; European and Developing Countries Clinical Trials Partnership...

Completed

Tenofovir/Emtricitabine for PMTCT in Africa and Asia (ANRS 12109 TEmAA) (TEmAA)

HIV Infection | Pregnancy

Cambodia, South Africa, Côte D'Ivoire
Drugs for Neglected Diseases
University of Cape Town; Medecins Sans Frontieres, Netherlands; UBS Optimus Foundation and other collaborators

Completed

Pharmacokinetics of Lopinavir/Ritonavir Superboosting in Infants and Young Children Co-infected With HIV and TB

Acquired Immunodeficiency Syndrome | Tuberculosis

South Africa
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs

Tuberculosis | AIDS-related Complex

United States, South Africa
International AIDS Vaccine Initiative
Targeted Genetics Corporation

Completed

Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid (TGC14F)

HIV Infections | Human Immunodeficiency Virus Infections

Uganda, South Africa, Zambia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Teriparatide (Forsteo) Treatment in Postmenopausal Women: Mechanism of Action (Forsteo)

Osteoporosis

United Kingdom
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Faster Identification of TB and Evaluation of Drug Resistance in HIV-infected People (FASTER)

HIV Infections

Peru, Brazil, South Africa
International Agency for Research on Cancer
World Health Organization; Cheikh Anta Diop University, Senegal; Walter Sisulu... and other collaborators

Active, not recruiting

The Study for the "Cervical Cancer Screening and Treatment Algorithms Study Using HPV Testing in Africa" (CESTA)

HPV Infection

Senegal, South Africa
CONRAD
United States Agency for International Development (USAID); Bill and Melinda...

Terminated

Cellulose Sulfate and HIV Transmission Among Women

HIV Infection

India, South Africa, Benin, Uganda
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

HIV Prevention Preparedness Study

HIV Infections | HIV Seronegativity

South Africa, Zambia, Tanzania

Clinical Trials on Bone Neoplasms in South Africa

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