Clinical Trials on Cancer of Brain and Nervous System in Japan

Total 1412 results

H. Lundbeck A/S

Active, not recruiting

A Study of Lu AF82422 in Participants With Multiple System Atrophy (AMULET)

Multiple System Atrophy

United States, Japan
Kyorin University

Completed

Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy

Normal Tension Glaucoma | Macular Retinoschisis | Macular Detachment

Japan
Kyushu University
Novartis; Kurume University; Fukuoka University; University of Occupational and... and other collaborators

Unknown

Ranibizumab Treatment for Age-Related Macular Degeneretion (QUATRO)

Visual Disorder Due to Age-related Macula Degeneration

Japan
Nippon Shinyaku Co., Ltd.

Active, not recruiting

Extension Study of NS-089/NCNP-02 in DMD

Duchenne Muscular Dystrophy (DMD)

Japan
Hoffmann-La Roche

Active, not recruiting

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)

Melanoma | Renal Cell Carcinoma | Adult Solid Tumor | Breast Cancer | Head and Neck Neoplasms | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Tumors | Lymphoma, Large-Cell, Anaplastic | Cholangiocarcinoma | Papillary Thyroid Cancer | Sarcomas | Salivary Gland Cancers and other conditions

United States, China, Korea, Republic of, Australia, Taiwan, France, Spain, United Kingdom, Hong Kong, Belgium, Italy, Germany, Japan, Singapore, Netherlands, Poland
Eli Lilly and Company

Completed

A Study of Galcanezumab (LY2951742) in Adults With Treatment-Resistant Migraine (CONQUER)

Migraine

Korea, Republic of, United States, Spain, Germany, Canada, United Kingdom, Czechia, Netherlands, Puerto Rico, Belgium, Japan, France, Hungary
Chinese University of Hong Kong

Recruiting

AG & IM in CA Stomach Protocol

Gastric Cancer | Intestinal Metaplasia | Atrophic Gastritis

Hong Kong, Japan, Singapore, Thailand
UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
Novartis Pharmaceuticals

Completed

PCA062 in pCAD-positive Tumors.

Esophageal Cancer | Triple Negative Breast Cancer | Head & Neck Cancer

France, Singapore, Italy, Japan, United States, Spain
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Cervical Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Renal Pelvis Cancer | Urinary Bladder Neoplasm | Recurrent...

United States, Japan, Australia
Amicus Therapeutics

Active, not recruiting

A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With LOPD

Pompe Disease (Late-onset)

United States, Germany, Taiwan, Belgium, Australia, Slovenia, Spain, Netherlands, Hungary, Japan, Austria, United Kingdom, France, Argentina, Canada, Sweden, Denmark, New Zealand, Greece, Korea, Republic of, Bosnia and Herzegovina, Ita... and more
AbbVie

Enrolling by invitation

Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Episodic Migraine

Episodic Migraine

United States, Canada, Denmark, Hungary, Italy, Poland, Puerto Rico, Spain, United Kingdom, Israel, Japan, Sweden
Japan Liver Oncology Group

Unknown

Sonazoid Enhanced Liver Cancer Trial for Early Detection

Liver Cirrhosis | Hepatitis B | Hepatocellular Carcinoma | Hepatitis C

Japan
Suzuka Hospital
Nagoya University

Unknown

The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy

Cardiomyopathies | Duchenne Muscular Dystrophy

Japan
Hoffmann-La Roche

Recruiting

Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease

Alzheimers Disease

Korea, Republic of, United States, Poland, Canada, Spain, Australia, Japan, Chile, United Kingdom
Medical University of South Carolina

Recruiting

Stroke Thrombectomy and Aneurysm Registry (STAR)

Stroke | Thromboses, Intracranial | Aneurysm, Brain

United States, Spain, Korea, Republic of, Germany, Switzerland, Canada, Argentina, Japan, Portugal, Uruguay, Egypt
Kyoto University, Graduate School of Medicine

Completed

Effects of Antihypertensive Drugs in Patients With Hypertension and Obstructive Sleep Apnea (OSA)

Hypertension | Obstructive Sleep Apnea

Japan
UCB Biopharma SRL

Enrolling by invitation

A Study to Test the Safety/ Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization

Epilepsy | Partial Seizures With or Without Secondary Generalization

China, Japan
Genzyme, a Sanofi Company

Completed

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency (ASCEND)

Sphingomyelin Lipidosis

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Chile, France, Germany, Italy, Japan, Netherlands, Portugal, Spain, Tunisia, Turkey, United Kingdom
Pfizer

Completed

Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only)

Migraine

Japan
Osaka City University
Nihon University; Kurume University; Miyata Eye Hospital; Fukuoka Kinen Hospital; Kimura Eye and Internal Medicine Hospital

Completed

Retina Projection System Trials for Low Vision People

Vision, Low

Japan
Eli Lilly and Company

Recruiting

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine (REBUILD-1)

Episodic Migraine

United States, Spain, India, Mexico, Japan, Netherlands, Puerto Rico, Denmark, Italy, Germany
Translational Research Center for Medical Innovation...
Kagoshima University; Nippon Medical School

Completed

The Therapeutic Effects of Peroneal Nerve Functional Electrical Stimulation for Lower Extremity in Patients With Sub-acute Post-stroke Hemiplegia (RALLY)

Stroke

Japan
Boehringer Ingelheim

Terminated

Dose Escalation Study of BIBF 1120 in Combination With Carboplatin and PLD in Relapsed Ovarian Cancer (OC)

Ovarian Neoplasms

Japan
Celgene

Completed

A Study of Special Use Results Surveillance of Revlimid 5mg Capsules

Myelodysplastic Syndromes | Multiple Myeloma

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With α-glucosidase Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Amgen
Novartis

Recruiting

Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine (OASIS(EM))

Migraine

United States, Spain, Japan, Poland, Belgium, Canada, United Kingdom, Germany, Hungary, Italy, Colombia, Russian Federation, Portugal, Switzerland, Finland, Puerto Rico
National Institute on Deafness and Other Communication...

Completed

Genetic Linkage Studies of Stuttering

Stuttering

United States, Japan, Pakistan
Life Molecular Imaging SA

Completed

Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy Volunteers

Alzheimer Disease | Amyloid Beta-Protein

United States, Switzerland, Australia, Germany, Japan
Amicus Therapeutics

Completed

A Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Disease (PROPEL)

Pompe Disease (Late-onset)

United States, Australia, Korea, Republic of, Japan, Taiwan, Belgium, Slovenia, New Zealand, United Kingdom, France, Argentina, Canada, Spain, Bosnia and Herzegovina, Germany, Sweden, Hungary, Austria, Bulgaria, Denmark, Greece, I... and more
Genzyme, a Sanofi Company

Completed

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease (COMET)

Glycogen Storage Disease Type II;Pompe's Disease

Czechia, Taiwan, Belgium, Germany, Korea, Republic of, United States, Argentina, Australia, Austria, Brazil, Canada, Denmark, France, Hungary, Italy, Japan, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Switzerland, Turk... and more
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of 2 Dose Regimens of TEV-48125 Versus Placebo for the Preventive Treatment of Episodic Migraine

Migraine

United States, Canada, Czechia, Finland, Israel, Japan, Poland, Russian Federation, Spain
Eisai Co., Ltd.

Completed

Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease

Alzheimer's Type Dementia

Japan
Kindai University

Unknown

Prediction of Incidence of Liver Cancer by Use of Real-time Tissue Elastography (PICTURE)

Chronic Hepatitis B | Chronic Hepatitis C

Japan
Janssen Research & Development, LLC

Completed

A Safety and Efficacy Study of JNS024 Extended Release (ER) in Japanese and Korean Patients With Chronic Malignant Tumor-Related Cancer Pain

Pain

Japan, Korea, Republic of
Sanofi

Recruiting

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis

Israel, Korea, Republic of, United States, China, Canada, Puerto Rico, United Kingdom, Chile, Turkey, Japan
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine (HALO)

Migraine

United States, Canada, Czechia, Finland, Israel, Japan, Poland, Russian Federation, Spain
Novartis Pharmaceuticals
Mitsubishi Tanabe Pharma Corporation

Completed

Evaluate Efficacy and Safety of Fingolimod 0.5 mg Orally Once Daily Versus Placebo in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients.

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Spain, United States, Belgium, Germany, Italy, Israel, Australia, France, United Kingdom, Netherlands, Czechia, Japan, Canada, Greece, Poland
City of Hope Medical Center

Recruiting

Pancreatic Cancer Detection Consortium (PCDC)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Resectable | Pancreatic Carcinoma | Pancreatic Cancer Non-resectable | Pancreatic Cancer Stage III | Pancreatic Cancer Stage | Pancreatic Cancer Stage II | Pancreatic Cancer, Adult | Pancreatic... and other conditions

Korea, Republic of, United States, Japan
Bayer
Population Health Research Institute

Completed

Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain. (PACIFIC-STROKE)

Acute Non-cardioembolic Ischemic Stroke

Spain, Japan, Australia, Czechia, Sweden, United Kingdom, Netherlands, Belgium, Russian Federation, Hungary, Slovakia, China, Germany, Switzerland, France, Poland, Denmark, United States, Austria, Bulgaria, Finland, Italy, Portugal
AbbVie

Recruiting

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine (ECLIPSE)

Migraine

United Kingdom, Belgium, China, Czechia, Germany, Italy, Japan, Korea, Republic of, Poland, Portugal, Slovakia, Spain, Sweden, Taiwan
Tokyo Medical University

Completed

Perampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS)

ALS

Japan
Hoffmann-La Roche

Terminated

A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD)

Alzheimer Disease

United States, Korea, Republic of, Canada, Poland, Argentina, Australia, Italy, Japan, Netherlands, Spain, Switzerland, Turkey, Chile, Mexico, United Kingdom, Denmark, Russian Federation
Astellas Pharma Inc

Completed

A Study of FK199B to Compare Efficacy With Zolpidem by Polysomnography in Patients With Insomnia

Sleep Initiation and Maintenance Disorders

Japan
Zogenix International Limited, Inc., a subsidiary...

Completed

An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, United Kingdom, Spain, Belgium, Italy, Australia, Denmark, Germany, Canada, Japan, Netherlands, France
Genzyme, a Sanofi Company

Recruiting

Pompe Disease Registry Protocol

Glycogen Storage Disease Type II | Pompe Disease

Hungary, Croatia, Serbia, United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Denmark, France, Germany, Greece, Hong Kong, India, Indonesia, Israel, Italy, Japan, Jordan, Korea, Republic of, Kuwait and more
Pfizer

Terminated

A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients

Alzheimer Disease

Australia, France, Finland, Portugal, Spain, United Kingdom, Poland, Japan, Italy, Belgium, Switzerland, Netherlands, Chile, Slovakia, Sweden, New Zealand, South Africa
Eisai Limited

Completed

A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020

Alzheimer Disease

Japan
Astellas Pharma Inc

Completed

Specified Drug Use-Results Survey of Regnite

Restless Legs Syndrome

Japan
CSL Behring
ICON Clinical Research

Completed

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Treatment With Subcutaneous Immunoglobulin (IgPro20)

Polyradiculoneuropathy | Chronic Inflammatory Demyelinating Polyneuropathy

United States, Australia, Belgium, Canada, Czechia, Estonia, Finland, France, Germany, Israel, Italy, Japan, Netherlands, Poland, Spain, United Kingdom

Clinical Trials on Cancer of Brain and Nervous System in Japan

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