Clinical Trials on Cardiomyopathy, Familial in Spain

Total 185 results

Bristol-Myers Squibb

Terminated

Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities

Primary Familial Dilated Cardiomyopathy

United States, Germany, Spain, United Kingdom
Alnylam Pharmaceuticals

Completed

DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis

Familial Amyloidotic Cardiomyopathy (FAC)

United States, France, Spain, United Kingdom, Belgium, Brazil
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
Hospital General Universitario Gregorio Marañon
Ministerio de Sanidad, Servicios Sociales e Igualdad

Unknown

Mesenchymal Stem Cells for Idiopathic Dilated Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy

Spain
Abbott Medical Devices

Completed

Triple Chamber Pacing in Hypertrophic Obstructive Cardiomyopathy (HOCM) Patients - TRICHAMPION STUDY (TRICHAMPION)

Hypertrophic Cardiomyopathy With Obstruction

Spain
Hospital Clinic of Barcelona

Unknown

CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM (CARDIO-HCM)

Hypertrophic Obstructive Cardiomyopathy (HOCM)

Spain
Fundación Pública Andaluza Progreso y Salud
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intracoronary Infusion of Autologous Bone Marrow Cells for Treatment of Idiopathic Dilated Cardiomyopathy

Dilated Cardiomyopathy

Spain
Cristina Avendaño Solá

Recruiting

Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial) (EARLY-GENE)

Cardiomyopathy, Dilated

Spain
Adolfo Fontenla

Recruiting

Renal Denervation in Hypertrophic Cardiomyopathy (SNYPER-PS)

Hypertrophic Cardiomyopathy

Spain
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Hospital General Universitario Gregorio Marañon

Completed

Intraventricular Stasis in Non Ischemic Dilated Myocardiopathy (ISBIDCM)

Stroke | Thrombosis | Dilated Cardiomyopathy

Spain
Hospital General Universitario Gregorio Marañon
Hospital Clinic of Barcelona; University of Salamanca

Recruiting

Intraventricular Stasis In Cardiovascular Disease (ISBIFLOW)

Stroke | Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Thrombosis Cardiac

Spain
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Terminated

Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.

Idiopathic Dilated Cardiomyopathy

Spain
Pfizer

Completed

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology (TTRACK)

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Italy, Romania, France, Australia, Austria, Portugal, Slovakia, Slovenia, Spain, United Kingdom
Institut Investigacio Sanitaria Pere Virgili

Recruiting

Early Detection of Familial Hypercholesterolemia in Children (DECOPIN)

Familial Hypercholesterolemia | Familial Hypercholesterolemia - Homozygous | Familial Hypercholesterolemia - Heterozygous

Spain
SOM Innovation Biotech SA
Hospital Vall d'Hebron

Completed

Study of SOM0226 in Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy (FAP)

Spain
Fundación Hipercolesterolemia Familiar
Instituto de Salud Carlos III; Fundación Centro Nacional de Investigaciones...

Recruiting

The Spanish Familial Hypercholesterolaemia Cohort Study (SAFEHEART)

Familial Hypercholesterolaemia

Spain
Parc de Salut Mar

Completed

Conduction System Stimulation to Avoid Left Ventricle Dysfunction (STAY)

Heart Failure | Pacemaker-Induced Cardiomyopathy | Atrioventricular Block, Second and Third Degree

Spain
Hospital Universitario La Paz

Unknown

Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO (PreloaDren)

Sepsis | Systemic Inflammatory Response Syndrome | Shock | Dilated Cardiomyopathy | Low Cardiac Output

Spain
Hospital Clinic of Barcelona
Hospital Universitario Ramon y Cajal; Puerta de Hierro University Hospital; Fundación... and other collaborators

Completed

Spanish Atrial Fibrillation And Resynchronization Study (SPAREIII)

Atrial Fibrillation | Chronic Heart Failure | Cardiomyopathy, Dilated

Spain
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

ATTR Amyloidosis | Transthyretin (TTR)-Mediated Amyloidosis | Familial Amyloidotic Polyneuropathy (FAP) | Familial Amyloid Neuropathies

France, Germany, Portugal, United Kingdom, Sweden, Spain
Neurimmune AG

Completed

First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

Amyloid Transthyretin Cardiomyopathy

Germany, France, Netherlands, Spain
Ionis Pharmaceuticals, Inc.
AstraZeneca

Active, not recruiting

The CARDIO-TTRansform Scintigraphy Sub-study

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

United States, Spain
Institut National de la Santé Et de la Recherche...

Terminated

PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE Inhibitors (PRECARDIA)

Dilated Cardiomyopathy

France, Denmark, Germany, Italy, Netherlands, Spain, United Kingdom
BioVentrix
Ohio State University

Completed

Clinical Study of the BioVentrix Revivent TC for the Treatment of Ischemic Cardiomyopathy (ReviventTC1)

Heart Failure

Spain
Ionis Pharmaceuticals, Inc.
AstraZeneca

Active, not recruiting

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

United States, United Kingdom, Italy, Spain
The University of The West Indies

Completed

Effectiveness and Safety of Distal Left Transradial Access in Coronary Procedures.

Cardiovascular Diseases | Cardiomyopathies

Trinidad and Tobago
Consorcio Centro de Investigación Biomédica en...
Instituto de Salud Carlos III

Recruiting

Study of Personalized Allocation of Defibrillators in Non-ischemic Heart Failure (SPANISH-1)

Non-ischemic Dilated Cardiomyopathy

Spain
Fundació Institut de Recerca de l'Hospital de la...
Hospital Clinic of Barcelona

Completed

Familial Hypocalciuric Hypercalcemia: Clinical Aspects and Evolution

Familial Hypocalciuric Hypercalcemia

Spain
Pfizer

Recruiting

A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM)

Cardiomyopathy, Dilated | Bcl-2 Anathogene-3 (BAG3) Dilated Cardiomyopathy (DCM)

United States, Spain, Netherlands, Poland, United Kingdom
Hospital Clinic of Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer; Centro de Investigación...

Recruiting

Physiological Pacing for AV Block to Prevent Pacemaker-induced Cardiomyopathy (PHYSPAVB)

Conduction System Pacing | Conventional Ventricular Pacing

Spain
Hospital Sant Joan de Deu
Marcio Andres Foundation

Unknown

Cardiac Arrhythmias and Sudden Death in Patients Affected With Laminopathies

Cardiomyopathy Associated With Myopathy and Sudden Death

Spain
Cytokinetics

Completed

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM (REDWOOD-HCM)

Hypertrophic Cardiomyopathy (HCM)

United States, Spain, Italy, Netherlands
Mallinckrodt

Completed

Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing

Idiopathic Pulmonary Arterial Hypertension | Cardiomyopathy

United Kingdom, United States, France, Spain, Netherlands
Bristol-Myers Squibb

Active, not recruiting

A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM

Hypertrophic Cardiomyopathy | Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Hypertrophic Cardiomyopathy

Denmark, United States, Belgium, Czechia, France, Germany, Israel, Italy, Netherlands, Poland, Portugal, Spain, United Kingdom
Pfizer

Completed

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045. (TRAMA)

Polyneuropathy | Hereditary Transthyretin Amyloidosis (ATTRv)

Spain
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, Germany, France, China, Israel, Italy, Hungary, Canada
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Portugal, Poland, Hungary, Denmark, Netherlands, Germany, Czechia
Hospital Universitari Vall d'Hebron Research Institute

Completed

Repeatability of OCT and IV-US in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Spain
MyoKardia, Inc.

Completed

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, France, Germany, Czechia, Spain, Belgium, Denmark, Portugal, Netherlands, Israel, Poland, United Kingdom, Italy
Bial - Portela C S.A.

Completed

Pharmacokinetics, Safety and Efficacy of BIA 5-1058 in PAH

Pulmonary Arterial Hypertension

Spain
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Hospital Universitario Virgen de la Arrixaca
Biosense Webster, Inc.

Unknown

SmartTouch Catheter in Ablation of Ventricular Tachycardia

Myocardial Infarction | Arrhythmias, Cardiac | Cardiomyopathies | Tachycardia, Ventricular

Spain
Pfizer

Completed

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy (ATTR-ACT)

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Spain, Czechia, Canada, Belgium, Netherlands, Germany, Japan, France, United Kingdom, Brazil, Italy, Sweden
Amryt Pharma

Active, not recruiting

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Homozygous Familial Hypercholesterolaemia (HoFH)

Germany, Israel, Italy, Saudi Arabia, Spain, Tunisia
Maastricht University
Medtronic; ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

LVSP vs RVP in Patients With AV Conduction Disorders (LEAP)

Atrioventricular Block | Pacing-Induced Cardiomyopathy | Cardiac Pacing | Conduction System Pacing | Left Ventricular Septal Pacing

Spain, Netherlands, Belgium, Czechia, Italy, Switzerland, Poland
Fundación Hipercolesterolemia Familiar

Completed

Alirocumab and Plaque Burden In Familial Hypercholesterolaemia (ARCHITECT)

Familial Hypercholesterolemia

Spain
Sociedad Española de Arteriosclerosis
Universidad de Zaragoza; Hospital Miguel Servet

Unknown

Cardiovascular Disease in FH Heterozygous

Familial Hypercholesterolemia

Spain
Pfizer

Completed

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Transthyretin (TTR) Amyloid Cardiomyopathy

United States, Taiwan, Canada, Belgium, Australia, Czechia, Sweden, Spain, Italy, Hong Kong, Germany, Netherlands, United Kingdom, France, Japan, Argentina, Brazil
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome (FCS)

South Africa, Spain, France, Germany, United Kingdom, United States, Canada, Netherlands

Clinical Trials on Cardiomyopathy, Familial in Spain

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