Clinical Trials on Central Nervous System Bacterial Infections

Total 171782 results

Kasey Phifer

Terminated

PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics (PEMF)

Lyme Disease | Lyme Arthritis | Lyme Neuroborreliosis | Unknown Origin Fever

United Kingdom
Hospices Civils de Lyon

Completed

Staphylococcus Lugdunensis Prosthetic Joint Infection

Staphylococcal Infections | Prosthetic Joint Infection

France
Assistance Publique Hopitaux De Marseille

Unknown

Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care Unit (STP-ATB-REA)

Infection, Bacterial
University of Duhok

Not yet recruiting

Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction

Infection, Bacterial
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

Bacterial Infection

United States, Bulgaria
National Institute of Allergy and Infectious Diseases...

Completed

Gene Expression in HIV and Tuberculosis Co-infection

Tuberculosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Infection and Cardiovascular Disease

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Helicobacter Infections | Cytomegalovirus Infections | Chlamydia Infections | Infection | Cerebrovascular Accident
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Skin Diseases, Bacterial

Hong Kong, Korea, Republic of, United States, Philippines, Singapore, Canada, Thailand, Israel, Taiwan, Lebanon, Malaysia, South Africa
Arpida AG

Completed

Study of Intravenous (I.V.) Iclaprim Versus Linezolid in Complicated Skin and Skin Structure Infections [cSSSI] (ASSIST-2)

Skin Diseases, Bacterial

United States
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections

Skin Diseases, Bacterial
Novartis
Novartis Vaccines

Completed

Immune Response Induced by a Vaccine Against Group B Streptococcus and Safety in Pregnant Women and Their Offsprings

Bacterial Infection | Streptococcal Infection | Gram-positive Bacterial Infection

Belgium, Canada
University Hospital, Brest
Centre de Référence des Infections Ostéo-Articulaires du Grand Ouest

Completed

Retrospective Study of Bone Infection Due to Campylobacter Spp (CAMPYLO)

Bone Diseases, Infectious | Campylobacter Infections

France
Mayo Clinic
Ortho-McNeil, Inc.

Completed

The Utility of Levofloxacin-Rifampin in the Therapy of Prosthetic Joint Infection

Staphylococcal Infection | Staphylococcus Aureus Prosthetic Joint Infection

United States
University of Alabama at Birmingham

Terminated

Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates

Respiratory Tract Infections | Bacteria Infection

United States
Pfizer
Allergan

Terminated

Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

Gram-negative Bacterial Infection

United States, Hungary, Slovakia, Taiwan, India, Estonia, Greece, Italy
Pfizer

Completed

Safety, Pharmacokinetics (PK) and Tolerability Study of a Novel Drug for Treatment of Bacterial Infections

Gram-negative Bacterial Infection

Australia
Southwest Oncology Group
University of Michigan; Hope Foundation

Completed

S1119 Peruvian H. Pylori Water Contamination Study

Helicobacter Pylori Infection

Peru
University Hospital, Clermont-Ferrand

Unknown

Ceftazidime Pharmacokinetic in Cerebrospinal Fluid Between Continuous and Intermittent Administration

Pseudomonas Aeruginosa Meningitis
Jena University Hospital

Terminated

PERFORM = Pentaglobin® Registry For Outcome Report and Monitoring (PERFORM)

Severe Bacterial Infection

Brazil, Colombia, Germany, Turkey
Central Hospital, Nancy, France

Completed

Antistaphylococcal Betalactam and Emergence of Resistance (CePasR)

Bacterial Resistance | Methicillin-Sensitive Staphylococcus Aureus Infection

France
Sanofi Pasteur, a Sanofi Company

Completed

Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age

Pertussis | Tetanus | Diphtheria | Meningitis | Meningococcal Infection | Haemophilus Influenzae Serotype b (Hib)

United States, Puerto Rico
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Completed

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Relative Bioavailability Study in Healthy Subjects (PDF112034)

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Three-part Study to Determine the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Volunteers and Healthy Male Japanese Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Amoxicillin Bioequivalence Study Brazil - Fast

Infections, Bacterial

Brazil
GlaxoSmithKline

Withdrawn

A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Women

Infections, Bacterial
Asan Medical Center

Enrolling by invitation

Development of Automated Molecular Diagnostic Platform for Tuberculosis Diagnosis (New Assay TB) (New Assay TB)

Tuberculosis Infection

Korea, Republic of
Aeras
Statens Serum Institut

Completed

A Phase I Randomized Placebo-Controlled, Double-Blind Study to Evaluate Safety and Immunogenicity of AERAS-404 Administered as Different Amounts of Antigen and Adjuvant Combinations in HIV-Negative BCG-Vaccinated Adults Without Evidence of Tuberculosis Infection

Tuberculosis

Sweden
University of Maryland, Baltimore

Terminated

Targeted Gown and Glove Intervention in Nursing Homes (TAGG)

Staphylococcus Aureus | Carbapenem Resistant Gram Negative Bacteria

United States
Sir Run Run Shaw Hospital
University of Birmingham

Unknown

Gram-negative Bacilli and MRSA Screening in ICU in China

Infections, Bacterial

China
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus

Infections, Bacterial

United States
GlaxoSmithKline

Withdrawn

A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.

Infections, Bacterial
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Effect of GSK1322322 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers

Infections, Bacterial
King Faisal University

Suspended

In Vitro Activity of Tigecycline Among Key Bacterial Pathogens Exhibiting Multidrug Resistance

Infections, Bacterial

Saudi Arabia
University of Vermont

Completed

Evaluation of Safety, Reactogenicity and Immunogenicity of Fractional-dose Inactivated Polio Vaccine (fIPV) Given Intradermally With Double Mutant Enterotoxigenic Escherichia Coli Heat Labile Toxin (dmLT) Adjuvant

Polio

United States
National Institute of Respiratory Diseases, Mexico
Hospital General Dr. Manuel Gea González; National Institute of Medical Sciences... and other collaborators

Not yet recruiting

Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City (PREVALIOCDMX)

Acquired Immunodeficiency Syndrome | Cryptococcal Meningitis | Tuberculosis Infection | Histoplasmosis AIDS

Mexico
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV

Gram-Negative Bacterial Infections | Bacteremia Caused by Gram-Negative Bacteria | Gram Negative Pneumonia
University of Oxford

Completed

An Alternative Booster Vaccine Against Meningitis and Ear Infections

Invasive Streptococcus Pneumoniae Disease

United Kingdom
GlaxoSmithKline

Completed

GSK1322322 Versus Linezolid in the Treatment of Acute Bacterial Skin and Skin Structure Infection

Skin Infections, Bacterial

United States
Children's Mercy Hospital Kansas City
University of Kansas Medical Center; Midwest Cancer Alliance

Completed

High and Low Resource Interventions to Promote HPV Vaccines

Communication | Meningitis, Meningococcal | Satisfaction | Human Papilloma Virus | Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination

United States

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