Clinical Trials on Central Nervous System Bacterial Infections in Belgium

Total 4868 results

Gilead Sciences

Terminated

Safety and Efficacy of Andecaliximab (GS-5745) in Adults With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Australia, France, Poland, Ukraine, Switzerland, Romania, Canada, Netherlands, Korea, Republic of, Belgium, Russian Federation, Taiwan, New Zealand, Hungary, United Kingdom, Bulgaria, Latvia, Czechia, Slovakia, Italy and more
BioNTech SE

Recruiting

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (AHEAD-MERIT)

Recurrent Head and Neck Cancer | Unresectable Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Cancer

Germany, United States, France, United Kingdom, Korea, Republic of, Spain, Poland, Belgium, Brazil, Taiwan, Italy, Canada, Czechia, Australia, Turkey, Mexico, Chile, Argentina, Austria, Hungary, Portugal, Sweden
European Inter-group Cooperation on Childhood and...

Unknown

Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma

Lymphoma

France, United Kingdom, Germany, Italy, Belgium, Switzerland, Austria, Czech Republic, Ireland, Netherlands, Poland, Sweden
UCB Pharma

Completed

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

United States, Belgium, United Kingdom
Ablynx, a Sanofi company

Completed

Study to Assess Efficacy and Safety of Anti-von Willebrand Factor (vWF) Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP) (TITAN)

Acquired Thrombotic Thrombocytopenic Purpura

United States, Austria, Belgium, France, Germany, Israel, Italy, Spain, Switzerland, United Kingdom, Bulgaria, Romania, Australia
AstraZeneca

Completed

Nexium Dyspepsia/AST

Signs and Symptoms, Digestive | Dyspepsia | Gastrointestinal Disease

Mexico, South Africa, United Kingdom, Hungary, Finland, Norway, Canada, Austria, France, Sweden, Germany, Belgium, Switzerland
Medtronic

Recruiting

Enlighten Study: The EV-ICD Post Approval Registry

Tachycardia | Ventricular Arrhythmia

United States, Switzerland, Spain, Netherlands, Finland, France, Germany, Denmark, Sweden, Czechia, Canada, United Kingdom, Belgium, Poland, Austria, New Zealand, Norway, Portugal, Kuwait, Greece, Hungary
Eli Lilly and Company

Completed

A Study of Prexasertib (LY2606368) in Platinum-Resistant or Refractory Recurrent Ovarian Cancer

Ovarian Cancer

United States, Israel, Spain, Korea, Republic of, Australia, Belgium, United Kingdom, Italy
EBMT Solid Tumors Working Party
Lymphoma Trials Office

Completed

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma

Lymphoma

France, Spain, United Kingdom, Australia, Israel, Poland, Belgium, Switzerland, Canada, Germany, Denmark, New Zealand, Austria, Portugal, Turkey, Czech Republic, Sweden
Bristol-Myers Squibb

Completed

Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

Korea, Republic of, United States, Australia, Hungary, Germany, Italy, United Kingdom, Czechia, Japan, Russian Federation, France, Belgium, Poland
Hoffmann-La Roche

Completed

A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors (GARDENIA)

Ulcerative Colitis

Spain, United Kingdom, Belgium, Korea, Republic of, Austria, Czechia, France, Hungary, Italy, Netherlands, Singapore, Portugal, Canada, Germany, South Africa, Switzerland, Romania, Norway, Sweden, Israel
PTC Therapeutics

Terminated

Extension Study of Ataluren in Participants With Nonsense Mutation Cystic Fibrosis

Cystic Fibrosis

United States, Spain, France, Belgium, United Kingdom, Australia, Brazil, Bulgaria, Canada, Germany, Israel, Italy, Netherlands, Poland, Argentina, Greece
Tobira Therapeutics, Inc.

Completed

Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis (CENTAUR)

Nonalcoholic Steatohepatitis

Belgium, Spain, Hong Kong, United States, France, Germany, Australia, United Kingdom, Poland, Italy
Ionis Pharmaceuticals, Inc.

Completed

OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE)

Hereditary Angioedema

United States, France, Netherlands, Spain, United Kingdom, Belgium, Bulgaria, Canada, Denmark, Germany, Israel, Italy, Poland, Turkey
Merck Sharp & Dohme LLC

Active, not recruiting

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

Colorectal Cancer

United States, Poland, Belgium, Canada, Colombia, Costa Rica, Denmark, Estonia, France, Germany, Greece, Guatemala, Hungary, Italy, Korea, Republic of, Lithuania, Netherlands, Romania, Russian Federation, Spain, Turkey, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of Long-term Treatment With TEZ/IVA in CF Participants With an F508del CFTR Mutation

Cystic Fibrosis

United States, Germany, United Kingdom, Canada, Australia, Switzerland, France, Ireland, Belgium, Denmark, Poland
Bayer

Completed

Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM) (STORM)

Carcinoma, Hepatocellular

Belgium, France, Spain, China, Hong Kong, United States, Canada, Switzerland, Germany, Portugal, Taiwan, Japan, Russian Federation, Singapore, Austria, United Kingdom, Korea, Republic of, Australia, New Zealand, Mexico, Brazil, Italy and more
Sanofi
Regeneron Pharmaceuticals

Completed

Safety and Quality of Life Study of Aflibercept in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

Colorectal Cancer Metastatic

Italy, Spain, United Kingdom, Czechia, Russian Federation, Norway, Thailand, Chile, Israel, Brazil, United States, Belgium, Canada, Denmark, Finland, Germany, Ireland, Lebanon, Mexico, Netherlands, Puerto Rico, Sweden, Turkey
Intergroupe Francophone du Myelome

Active, not recruiting

Evaluation of the Impact of the Update SMM Criteria on the Natural History of SMM to Establish New Recommendations. (CARRISMM)

Smoldering Multiple Myeloma

France, Belgium, Monaco
Amgen

Terminated

Pediatric Chronic Kidney Disease Safety and Efficacy

Hyperparathyroidism | Chronic Kidney Disease | Secondary Hyperparathyroidism | Hyperparathyroidism, Secondary | Kidney Disease

United States, Belgium, Hungary, Spain, Australia, Germany, Poland, Mexico, Russian Federation, Slovakia
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of Tezacaftor (VX-661) in Combination With Ivacaftor (VX-770) in Subjects Aged 12 Years and Older With Cystic Fibrosis (CF), Who Have One F508del-CFTR Mutation and a Second Mutation That Has Been Demonstrated to be Clinically Responsive to Ivacaftor

Cystic Fibrosis

United States, Australia, Canada, United Kingdom, Germany, Belgium, Austria, Ireland, Italy, France
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
Shire

Completed

Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis

Ulcerative Colitis

United States, France, Spain, Ireland, Czechia, Poland, Colombia, Canada, Romania, India, United Kingdom, South Africa, Belgium, Germany, Hungary
Merck Sharp & Dohme LLC
Seagen Inc.; Astellas Pharma Global Development, Inc.

Active, not recruiting

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

Urinary Bladder Cancer, Muscle-invasive

Canada, United States, Australia, Belgium, France, Hungary, Italy, Korea, Republic of, Mexico, Poland, Russian Federation, Thailand, Ukraine, Argentina, Colombia, Denmark, Germany, Ireland, Israel, Japan, Malaysia, Philippines, Sing... and more
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents

Gastroesophageal Reflux Disease | Erosive Esophagitis

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescents

Gastroesophageal Reflux Disease

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
ImmunoGen, Inc.

Active, not recruiting

IMGN853 With Carboplatin in Second-line Treatment of FRα Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | High Grade Ovarian Cancer

United States, United Kingdom, Belgium, Spain, Canada, Georgia
Boston Scientific Corporation

Completed

Safety and Performance Study of the INGEVITY Lead

Bradycardia | Sinus Node Dysfunction

United States, Belgium, Germany, Canada, Spain, Sweden, Italy, Malaysia, Denmark, Australia, Austria, United Kingdom, Hong Kong, France, Portugal, Thailand
Janssen Research & Development, LLC
Janssen Biologics BV

Completed

A Long Term Safety Study of Infliximab (Remicade) in in Ulcerative Colitis Patients

Ulcerative Colitis

United States, France, United Kingdom, Belgium, Switzerland, Israel, Canada, Australia, Netherlands, New Zealand, Austria, Germany, Denmark, Czechia, Argentina
Abbott

Completed

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Argentina, Australia, Austria, Belgium, Canada, Czech Republic, Denmark, France, Germany, Hungary, Israel, New Zealand, Norway, Poland, Portugal, Spain, Switzerland
Takeda
Takeda Development Center Americas, Inc.

Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency

United States, Belgium, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Spain, Portugal, Italy, Poland, Brazil
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

Unresectable, Recurrent, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma | Gastric Cancer Third Line

Spain, Italy, Australia, Korea, Republic of, Belgium, France, Poland, United States, Czechia, Germany
Proteostasis Therapeutics, Inc.

Completed

Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis

Healthy Volunteer - Complete | Cystic Fibrosis - Complete

United States, Belgium, United Kingdom, France, Germany, Canada, Denmark, New Zealand, Australia
AstraZeneca

Recruiting

Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents

Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer

Spain, United States, Belgium, United Kingdom, France, Hungary, Canada, Korea, Republic of, Australia
Actelion

Terminated

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients (DUAL-2)

Digital Ulcers

Spain, United States, Argentina, China, Ireland, Colombia, Israel, New Zealand, Germany, Belgium, Portugal, Netherlands, South Africa, Greece, Mexico, Poland, Puerto Rico, Russian Federation, Turkey, Ukraine, United Kingdom
Sirtex Medical

Completed

FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer (SIRFLOX)

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma

United States, Israel, Australia, Belgium, New Zealand, Spain, Germany, Switzerland, Italy, France, Poland
Boehringer Ingelheim
Eli Lilly and Company

Completed

Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus

Obesity | Diabetes Mellitus, Type 2

United States, Belgium, Bulgaria, Colombia, Czech Republic, Finland, France, Germany, Guatemala, Mexico, Peru, Russian Federation, Spain, Ukraine
AstraZeneca

Completed

Nexium Dyspepsia/AST

Signs and Symptoms, Digestive | Dyspepsia | Gastrointestinal Disease

Sweden, Brazil, France, Italy, South Africa, Spain, Germany, Romania, Denmark, Norway, Canada, Argentina, Belgium, Greece, Iceland, Switzerland, Singapore
AbbVie

Completed

Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease

Crohn's Disease

United States, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Puerto Rico, Romania, Slovakia, Spain, Switzerland, Ukraine, United Kingdom
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Hereditary Angioedema

United States, Puerto Rico, Belgium, Bulgaria, Canada, France, Germany, Israel, Italy, Netherlands, Poland, Spain, Turkey, United Kingdom
Quark Pharmaceuticals

Completed

PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME) (MATISSE)

Diabetic Retinopathy | Diabetic Macular Edema | Choroidal Neovascularization

United States, Israel, United Kingdom, Belgium, Germany, Poland, Czech Republic
Sanofi

Recruiting

Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (MAYARI)

Thrombotic Thrombocytopenic Purpura

Italy, Belgium, France, Greece, United States, Austria, Canada, Czechia, Germany, Japan, Netherlands, Spain, United Kingdom
AbbVie

Terminated

Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis

Cystic Fibrosis (CF)

United States, Australia, Belgium, Hungary, Netherlands, New Zealand, Slovakia, United Kingdom
Sanofi

Completed

Obese Patients With Type 2 Diabetes (RIO-Diabetes)

Obesity | Diabetes Mellitus, Non-Insulin-Dependent | Obesity in Diabetes

United States, France, Canada, Poland, Germany, Netherlands, Belgium, Czech Republic, Argentina, Finland, United Kingdom
Takeda

Recruiting

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis

Belgium, Australia, Israel, United States, Hungary, Korea, Republic of, China, Canada, Croatia, Italy, Poland, Slovakia, United Kingdom, Japan, Greece
Sanofi
Regeneron Pharmaceuticals; NSABP Foundation Inc

Completed

Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen (VELOUR)

Neoplasm Metastasis | Colorectal Neoplasms

Italy, Austria, Estonia, Spain, South Africa, Belgium, Puerto Rico, United Kingdom, Sweden, United States, Argentina, Australia, Brazil, Chile, Czech Republic, Denmark, France, Germany, Greece, Korea, Republic of, Netherlands, New... and more
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer.

Colorectal Cancer

Belgium, France, Germany, Spain, Sweden, Estonia, Portugal, Austria, Switzerland, Denmark, Czech Republic, Finland, Saudi Arabia, Netherlands, Norway
Shire

Completed

Long-Term Safety Of PF-00547659 In Ulcerative Colitis (TURANDOT II)

Ulcerative Colitis

Korea, Republic of, United States, Spain, Australia, Canada, Israel, Serbia, Netherlands, Belgium, Italy, New Zealand, Austria, Bulgaria, Czechia, France, Germany, Hungary, Poland, Russian Federation, Slovakia, South Africa
Pfizer

Completed

Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors

Arthritis, Rheumatoid

Australia, United States, Austria, Germany, Ireland, Brazil, Spain, Taiwan, Belgium, Canada, France, Italy, Korea, Republic of, Puerto Rico
AbbVie

Completed

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

Cystic Fibrosis

United States, Belgium, Canada, Czechia, France, Hungary, Netherlands, New Zealand, Poland, Slovakia, United Kingdom, Serbia

Clinical Trials on Central Nervous System Bacterial Infections in Belgium

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