Clinical Trials on Child Development

Total 5610 results

Hospital de Clinicas de Porto Alegre
The Isaac Foundation

Active, not recruiting

Evaluation of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI

Mucopolysaccharidoses | Mucopolysaccharidosis VI | Morquio A Syndrome | Mucopolysaccharidosis IV A | MPS IV A | MPS VI | MPS - Mucopolysaccharidosis | Morquio Syndrome A | Morquio Syndrome

Brazil
UCSF Benioff Children's Hospital Oakland
Genentech, Inc.

Completed

Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas (Vismodegib)

Basal Cell Nevus Syndrome | Gorlin's Syndrome

United States
Anne Chang
Novartis Pharmaceuticals

Terminated

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Carcinoma, Basal Cell | Skin Neoplasms | Basal Cell Nevus Syndrome | Recurrent Skin Cancer

United States
Premier Specialists, Australia

Unknown

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex Kobner | Weber-Cockayne Syndrome

Australia
Yale University
National Cancer Institute (NCI)

Completed

Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants

Non-melanomatous Skin Cancer | Neoplastic Syndrome
University of British Columbia

Recruiting

Global Hip Dysplasia Registry (GHDR)

Hip Dislocation, Congenital | Congenital Hip Dysplasia | Congenital Dysplasia of the Hip | Congenital Hip Dislocation | Hip Dysplasia, Congenital, Nonsyndromic | Congenital Hip Displacement | Dislocation Of Hip, Congenital | Dislocation, Congenital Hip | Displacement, Congenital Hip | Dysplasia, Congenital... and other conditions

Canada
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Surgical Treatment of Marfan Syndrome With Subluxation Lens

Marfan Syndrome | Lens Subluxation or Dislocation

China
Stanford University

Completed

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex Kobner | Weber-Cockayne Syndrome

United States
PellePharm, Inc.

Completed

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

Basal Cell Nevus Syndrome

United States, Spain, Germany, United Kingdom, Italy, France, Belgium, Canada, Denmark, Netherlands
University of Maryland, Baltimore

Completed

Trial of Lithium Carbonate for Treatment of Osteoporosis-pseudoglioma Syndrome

Osteoporosis Pseudoglioma

United States
Novo Nordisk A/S

Completed

Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers

Healthy | Prader-Willi Syndrome | Genetic Disorder | Growth Disorder | Idiopathic Short Stature

United States
Federico II University

Completed

Growth Hormone Deficiency in Chronic Heart Failure: A Preliminary Trial

Heart Failure | Ischemic Heart Disease | Growth Hormone Deficiency
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Scleral Buckling for Retinal Detachment Prevention in Genetically Confirmed Stickler Syndrome (STL-DR-PREV)

Stickler Syndrome

France
Seattle Children's Hospital
Children's Hospital of Philadelphia; University of North Carolina, Chapel Hill and other collaborators

Completed

Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology (CAUSE)

Craniofacial Microsomia | Goldenhar Syndrome | Microtia | Microtia-Anotia | OAVS | OAV Syndrome | Hemifacial Microsomia

United States, Colombia, Peru, Spain
Seattle Children's Hospital
Children's Hospital of Philadelphia; Northwestern University; New York University and other collaborators

Completed

Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK) (CLOCK)

Craniofacial Microsomia | Goldenhar Syndrome | Microtia | Hemifacial Microsomia | Oculo-Auriculo-Vertebral-Syndrome

United States
HedgePath Pharmaceuticals, Inc.

Completed

Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS)

Basal Cell Carcinoma in Basal Cell Nevus Syndrome

United States
Novartis Pharmaceuticals

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Basal Cell Carcinoma

Greece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
Nova Scotia Health Authority
University Health Network, Toronto

Terminated

Metal on Metal Versus Metal on Highly Crossed Linked Polyethylene Sytem (MOM)

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Ankylosing Spondylitis | Post-traumatic; Arthrosis | Congenital Dysplasia of the Hip | Injury of Hip and Thigh
QLT Inc.
Novartis

Terminated

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Nevoid Basal Cell Carcinoma Syndrome | Basal Cell Carcinoma | Gorlin Syndrome
University of Basel
Kantonsspital Aarau

Completed

Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions

Pheochromocytoma | Adrenal Tumor | Adrenal Mass | Adrenal Hyperplasia | Adrenal Metastases | Conn Adenoma

Switzerland
University of Calgary
Pfizer

Not yet recruiting

Growth Hormone Deficiency in Mild Traumatic Brain Injury

Growth Hormone Deficiency | Growth Hormone Treatment | Concussion Post Syndrome | Concussion, Mild
VA Office of Research and Development

Not yet recruiting

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD) (GRIT)

Mild Traumatic Brain Injury | Adult Growth Hormone Deficiency

United States
Zimmer Biomet

Active, not recruiting

Avenir® Cemented Hip Stem - PMCF

Femoral Neck Fractures | Congenital Hip Dysplasia | Primary Osteoarthritis | Femoral Head Necrosis | Sequelae From Previous Hip Surgery | Osteotomies | Post-Traumatic Osteoarthritis of Hip

Belgium, France
Istituto Ortopedico Rizzoli

Completed

Resilience and Coping in a Rare Skeletal Disease Population to Face Coronavirus (COVID-19) Outbreak Distress: a Longitudinal Study (RELOAD)

Osteogenesis Imperfecta | Multiple Osteochondroma | Ollier Disease | Maffucci Syndrome

Italy
University of Maryland, Baltimore
Children's Hospital of Philadelphia

Withdrawn

Growth Hormone for Osteoporosis Pseudoglioma Syndrome (GHOPPG)

Osteoporosis Pseudoglioma Syndrome

United States
Anglia Ruskin University
Mid and South Essex NHS Foundation Trust

Unknown

The Oscillation of Crystalline and Intraocular Lenses

Cataract | Pseudoexfoliation Syndrome | Ectopia Lentis | Marfan's Syndrome With Ocular Manifestations | Phakodonesis

United Kingdom
National Human Genome Research Institute (NHGRI)

Completed

Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants

Coronary Artery Disease | Proteus Syndrome | Familial Isolated Hyperparathyroidism | Coffin - Sins Syndrome | Dubouitz Syndrome

United States
M.M.A Tech Ltd.

Unknown

AL-2 MP-1 (Polyimide) Acetabular Liner

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Ankylosing Spondylitis | Post-traumatic; Arthrosis | Congenital Dysplasia of the Hip | Injury of Hip

Israel
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Nevoid Basal Cell Carcinoma Syndrome | Basal Cell Carcinoma | Gorlin Syndrome

Belgium, Austria, Germany, Canada
Children's Hospital Los Angeles
Genentech, Inc.

Completed

Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia

Growth Hormone Deficiency | Hypopituitarism | Septo-Optic Dysplasia

United States
Federico II University

Completed

Growth Hormone Deficiency in Chronic Heart Failure: an Observational Study

Heart Failure | Ischemic Heart Disease | Growth Hormone Deficiency | Cardiomyopathy

Italy
Children's Hospital Medical Center, Cincinnati
Lymphangiomatosis and Gorham's Disease Alliance (LGDA); Klippel Trenaunay (KT)... and other collaborators

Recruiting

Identification of Biomarkers for Patients With Vascular Anomalies

Kaposiform Hemangioendothelioma | Kaposiform Lymphangiomatosis | Vascular Anomaly | Klippel Trenaunay Syndrome | Generalized Lymphatic Anomaly | Gorham-Stout Disease | Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi

United States
Aesculap AG

Active, not recruiting

Cemented TrendHip® - Multicenter PMCF Study on Total Indications (TRESTI)

Rheumatoid Arthritis | Hip Dysplasia | Fractures, Hip | Necrosis, Femur Head | Coxarthrosis; Primary | Coxarthrosis; Post-Traumatic

Germany
National MPS Society
MediResource Inc.

Terminated

Study to Detect Unrecognized Mucopolysaccharidosis in Children Visiting Rheumatology, Hand or Skeletal Dysplasia Clinics

Mucopolysaccharidosis I | Mucopolysaccharidosis II | Mucopolysaccharidoses | Mucopolysaccharidosis VI | Mucopolysaccharidosis IV

United States
National Institute of Dental and Craniofacial Research...

Completed

A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome

McCune Albright Syndrome | Polyostotic Fibrous Dysplasia

United States
Rolfs Consulting und Verwaltungs-GmbH (RCV)
Rhythm Pharmaceuticals, Inc.

Recruiting

Early Genetic Identification of Obesity (WEGIO)

Cognitive Impairment | Hyperphagia | Obesity, Childhood | Bardet-Biedl Syndrome | Polydactyly | Retinopathy | Syndactyly | POMC Deficiency

Germany
IRCCS Policlinico S. Donato
University of Milan

Recruiting

Analysis of Muscular Properties in Patients With MFS and EDS (MUSCLE)

Marfan Syndrome | Rare Diseases | Ehlers-Danlos Syndrome

Italy
University of Minnesota

Recruiting

Natural History Study for DNA Repair Disorders

DNA Repair Disorder | Xeroderma Pigmentosum | Cockayne Syndrome | Trichothiodystrophy

United States
Center for Neurological Studies
Novo Nordisk A/S

Recruiting

Growth Hormone Replacement Therapy for Retried Professional Football Players

TBI (Traumatic Brain Injury) | Growth Hormone Deficiency | Hypopituitarism | Sport Injury | Concussion, Brain | Anterior Pituitary Hyposecretion Syndrome

United States
National Institute on Aging (NIA)

Completed

Studies of Heritable Disorders of Connective Tissue

Marfan Syndrome | Ehlers-Danlos Syndrome | Stickler Syndrome

United States
Freeman-Sheldon Research Group, Inc.

Terminated

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (STOP-FSS)

Craniofacial Abnormalities | Arthrogryposis | Freeman-Sheldon Syndrome | Arthrogryposis Distal Type 2A | Whistling Face Syndrome | Craniocarpotarsal Dysplasia | Craniocarpotarsal Dystrophy | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Arthrogryposis Distal Type 2B | Gordon Syndrome | Arthrogryposis... and other conditions

United States
Ascend Biopharmaceuticals Ltd

Completed

A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma (ASN-002-001)

Basal Cell Nevus Syndrome | Skin Neoplasm | Nodular Basal Cell Carcinoma of Skin

Australia
Novartis Pharmaceuticals

Completed

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients

Austria, Switzerland
Columbia University

Unknown

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Severe Combined Immunodeficiency | Fanconi Anemia | Bone Marrow Failure | Osteopetrosis

United States
Barts & The London NHS Trust

Recruiting

Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA

Acromegaly | Gigantism | Familial Isolated Pituitary Adenoma | FIPA | Pituitary Adenoma Predisposition | PAP

United Kingdom
Ascend Biopharmaceuticals Ltd

Suspended

Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)

Basal Cell Carcinoma in Basal Cell Nevus Syndrome

United States
King Edward Medical University

Unknown

Role of Mesenchymal Stem Cells in Fat Grafting

Lipodystrophy | Craniofacial Microsomia | Mixed Connective Tissue Disease | Romberg's Disease
Haukeland University Hospital
Karolinska Institutet; University Hospitals Bristol and Weston NHS Foundation... and other collaborators

Completed

Dynamic Hormone Diagnostics in Endocrine Disease (ultradian)

Congenital Adrenal Hyperplasia | Acromegaly | Growth Hormone Deficiency | Cushing Syndrome | Primary Hyperaldosteronism | Adrenal Insufficiency

Norway, Sweden, Greece, United Kingdom
Shanghai Jiao Tong University School of Medicine

Recruiting

China Adrenal Disease Registry (CASE)

Congenital Adrenal Hyperplasia | Cushing Syndrome | Pheochromocytoma | Adrenal Incidentaloma | Adrenal Adenoma | Adrenal Carcinoma | Aldosteronism | Hypoadrenalism

China
Hospices Civils de Lyon

Not yet recruiting

Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study (COGRare5)

Arteriovenous Malformations | Marfan Syndrome | Osler Rendu Disease | Vascular Anomaly | Lymphedema Primary | Cerebrospinal; Disorder

France

Clinical Trials on Child Development

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations