Clinical Trials on Chromosomal Triplication in France

Total 171 results

University Hospital, Montpellier

Unknown

Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations

Balanced Chromosomal Translocation

France
University Hospital, Grenoble

Completed

Diagnosis Accuracy of Noninvasive Screening by PCR Digital for Down Syndrom (DIgiT21)

Trisomy 21

France
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Active, not recruiting

Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells (ISETTRI21)

Trisomy 21

France
University Hospital, Brest

Recruiting

Biocollection in MyeloDysplastic Syndrome (P-MDS) (P-MDS)

Myelodysplastic Syndromes | Chromosome Abnormality | Acute Myeloid Leukemia With Multilineage Dysplasia | Myelodysplastic Syndrome With Ring Sideroblasts | Myelodysplastic Anemia | Myelodysplastic Syndrome With Isolated Del(5Q)

France
University Hospital, Strasbourg, France

Unknown

Trisomy 21 in Adulthood

Down Syndrome

France
Assistance Publique - Hôpitaux de Paris

Recruiting

A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults (GRAAPH2014)

Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia

France
University Hospital, Caen

Terminated

Non-invasive Screening of Fetal Trisomy 21 by Digital PCR (dPNI-T21)

Trisomy 21

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Multicenter Trial Treatment of Philadelphia Chromosome Negative B-cell Acute Lymphoblastic Leukemia of Young Adults (GRAALL-2014/B)

Philadelphia Chromosome Negative Adult B-cell Acute Lymphoblastic Leukemia

France
Assistance Publique - Hôpitaux de Paris

Completed

T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients (DEPOSA)

Trisomy 21, 18 and 13 Screening

France
Assistance Publique - Hôpitaux de Paris

Completed

Trisomy of Chromosome 21 Diagnosis by High Output Sequencing (SEQ21)

Trisomy 21 - Translocation

France
Hospices Civils de Lyon

Completed

Fertility Preservation in Cases of Klinefelter Syndrome. (FERTIPRESERVE)

Klinefelter Syndrome

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples (NT21)

Periodontitis | Trisomy 21

France
Igenomix

Recruiting

RCT Study to Validate niPGT-A Clinical Benefit. (niPGT-A_RCT)

Infertility | Aneuploidy | Chromosome Abnormality

France, Argentina, Spain, United States, Brazil, Italy
Assistance Publique - Hôpitaux de Paris

Completed

Social Cognition and Turner Syndrome (COGNITUR)

Turner Syndrome

France
Centre Hospitalier Universitaire Dijon

Unknown

Clinical and Molecular Characterisation of Orofaciodigital Syndromes and Other Clinical Phenotypes Secondary to Mutations in the OFD1 Gene (OFD1)

Orofaciodigital Syndromes

France
Novartis Pharmaceuticals

Completed

Nilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior Therapy

Philadelphia Chromosome Positive Chronic Myelogenous Leukemia

Germany, Canada, France, Spain, Italy
Ferring Pharmaceuticals

Terminated

Evaluation of the Adherence and the Patient Acceptability of Zomacton® Treatment With the Zomajet® Vision X Device (ZOMAXEPT)

Growth Hormone Deficiency | Turner's Syndrome

France
Merck KGaA, Darmstadt, Germany

Completed

Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years

Turner's Syndrome

France
Assistance Publique - Hôpitaux de Paris
Groupe Hospitalier Pitie-Salpetriere

Active, not recruiting

Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome (CRYO-X0)

Turner Syndrome | Ovarian Insufficiency

France
Central Hospital, Nancy, France

Completed

Is There a Link Between Inflammation and Endocrinopathies in Turner Syndrome?

Turner Syndrome

France
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Enrolling by invitation

Sexuality and Sexual Quality of Life in Adult Patients With Turner Syndrome (TS) Compared With Patients With Primary Ovarian Insufficiency Different From TS (SEXATURN)

Primary Ovarian Insufficiency | Turner Syndrome

France
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
Novartis Pharmaceuticals

Completed

An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis

Philadelphia Chromosome Positive CML

United States, Germany, Italy, France
University Hospital, Strasbourg, France

Recruiting

Identification of Y Chromosome From Free Circulating DNA in Patients With Turner Syndrome (Turner-Ylc)

Turner Syndrome

France
University Hospital, Tours

Completed

Glutaminergic Transmission in Autism : Molecular Imaging Exploration (TANGAU)

Healthy Volunteers | Autism | Fragile-X Syndrome (FXS)

France
Assistance Publique - Hôpitaux de Paris

Completed

Imatinib Mesylate With Vincristine and Dexamethasone in Acute Lymphoblastic Leukemias With BCR-ABL Positive (AFR07)

Blast Crisis | Philadelphia Chromosome | Leukemia, Lymphocytic, Acute | Leukemia, Myeloid, Chronic

France
Novartis

Completed

Efficacy, Safety and Tolerability of AFQ056 in Fragile X Patients

Fragile X Syndrome

France, Italy, Switzerland
University Hospital, Strasbourg, France

Active, not recruiting

AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome) (AVAST)

Lymphedema | Turner Syndrome | Peripheral Angiopathy | Vascular Malformation

France
Ferring Pharmaceuticals

Completed

An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG

Turner's Syndrome

Czech Republic, France, Netherlands
Université de Reims Champagne-Ardenne

Not yet recruiting

Gynaecological Follow-up of Women With Down Syndrom Aged 18 to 30 in France (Gyn-T21)

Down Syndrome

France
CHU de Reims

Unknown

Assessment of Women's Insight and Understanding of Down's Syndrome Screening by Non-invasive Prenatal Testing (NIPT) During Their First Ultrasound (DEPIST21)

Pregnancy

France
Institut Jerome Lejeune

Recruiting

Genetic and Epigenetic Variations in Heterokaryotypic Monozygotic Twins Discordant for Down Syndrome (Colibri)

Down Syndrome

France
Rennes University Hospital

Completed

Retrospective Study Using Next Generation Sequencing (NGS) on Biological Samples to Improve Genetic Counseling for Patients With Previously Explored Craniofacial Midline Defects. (EXOMEDIANE)

Holoprosencephaly

France
Hospices Civils de Lyon

Recruiting

Smith Magenis Syndrome Study (SMS)

Smith-Magenis Syndrome

France
Novo Nordisk A/S

Completed

Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Novo Nordisk A/S

Completed

Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone

Chronic Kidney Disease | Turner Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Delivery Systems | Foetal Growth Problem | Small for Gestational Age

France
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Correlations Phenotype / Genotype in Down Syndrome (INTREPID)

Down Syndrome

France
Institut Jerome Lejeune

Recruiting

Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin (BioJeL)

Intellectual Disability | Down Syndrome

France
Institut Jerome Lejeune
Hôpital Armand Trousseau

Completed

Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome

Down Syndrome

France
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome

Down Syndrome

France
University Hospital, Montpellier
Agence de La Biomédecine

Active, not recruiting

NIPD on cffDNA for Triplet Repeat Diseases

Fragile X Syndrome | Huntington Disease | Myotonic Dystrophy 1

France
Institut Jerome Lejeune
Central Hospital, Nancy, France; Hôpital Cochin

Completed

Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children (ACTHYF)

Down Syndrome

France
Novo Nordisk A/S

Completed

Growth Response in Girls With Turner Syndrome

Turner Syndrome | Genetic Disorder

France
Centre Leon Berard

Active, not recruiting

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase (TIPI)

Philadelphia Chromosome Positive CML | BCR-ABL Positive Chronic Myelogenous Leukemia

France
Takeda

Active, not recruiting

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL) | Ph+ Mixed Phenotype Acute Leukemia (MPAL) | Philadelphia Chromosome-Like ALL (Ph-like ALL)

United States, France, Korea, Republic of, China, Spain, United Kingdom, Czechia, Portugal, Brazil, Argentina, Italy, Australia, Mexico, Netherlands, Poland
Hôpital le Vinatier
Hospices Civils de Lyon

Completed

Melatonin in Adults With SMS (SMS-adults)

Smith Magenis Syndrome

France
University Hospital, Grenoble

Recruiting

Down Syndrome, Physical Activity and Sleep Apnea (TAPAS)

Down Syndrome

France
Rennes University Hospital
Novartis; Ministry of Health, France

Completed

Safety and Efficacy of Imatinib Added to Chemotherapy in Treatment of Ph+ Acute Lymphoblastic Leukemia in Children (ESPHALL)

Acute Lymphoblastic Leukemia | Philadelphia Chromosome

France
Assistance Publique - Hôpitaux de Paris

Completed

Non Invasive Prenatal Testing of Down Syndrome (SAFE 21)

Down Syndrome

France
University Hospital, Toulouse

Completed

Tolerance of Intranasal Administration of OT in Prader-Willi Newborn Babies (OTBB)

Prader-Willi Syndrome

France

Clinical Trials on Chromosomal Triplication in France

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