Clinical Trials on Chromosome 15q Duplication

Total 1326 results

Cindy Cisneros

Completed

Non-Invasive Chromosomal Evaluation of 22q11.2 (22Q)

22q.11.2 Deletion/Duplication

Belgium
Hospital Clínico Universitario de Valladolid

Completed

Genomic Instability in Vascular Surgeons (IRADIENT)

Radiation Exposure | Cytogenetic Abnormality

Spain
National Human Genome Research Institute (NHGRI)

Completed

Adaptation Among Adolescents and Adults With Klinefelter Syndrome

Klinefelter Syndrome

United States
University of Wisconsin, Madison
Solvay Pharmaceuticals

Withdrawn

Adaptive Behavior Assessment of Men With 49, XXXXY, Klinefelter Syndrome

Klinefelter Syndrome

United States
University of Aarhus
Aarhus University Hospital

Completed

Neuropsychologic, Neuroradiologic, Endocrinologic, and Genetic Aspects of Klinefelter Syndrome

Klinefelter Syndrome

Denmark
Boston Children's Hospital

Completed

Klinefelter Fertility Preservation

Klinefelter Syndrome

United States
University of Aarhus
Lundbeck Foundation; AP Moeller Foundation; The Korning Foundation Denmark

Completed

X-chromosome Inactivation, Epigenetics and the Transcriptome

Aortic Aneurysm | Turner Syndrome | Klinefelter Syndrome | Triple X Syndrome | 47 XYY Syndrome

Denmark
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY (TESTO)

Klinefelter Syndrome

United States
Renato Melaragno

Unknown

Phase II Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Chronic Myeloid Leukemia (CML) Philadelphia Chromosome-positive (Ph+)

Chronic Myeloid Leukemia (CML) With Philadelphia Chromosome-positive (Ph+)

Brazil
Bristol-Myers Squibb

Completed

A Study of Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia

Myeloid Leukemia, Chronic

Japan
Applied Spectral Imaging Ltd.

Completed

Detection of Chromosomal Aberrations in Non-small Cell Lung Cancer (NSCLC) Using Fluorescent in Situ Hybridization (FISH) (ALK Test)

Non-small Cell Lung Cancer (NSCLC)

United States
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States, Canada, Israel, Puerto Rico
Takeda

Active, not recruiting

A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

United States, China, Spain, Australia, Canada, Argentina, Korea, Republic of, Brazil, Japan, Italy, Mexico, France, Greece, Poland, Russian Federation, Austria, Taiwan, Bulgaria, Finland, Turkey
Hikma Pharmaceuticals LLC

Completed

Effectiveness and Safety Study of Generic Imatinib in Chronic Myeloid Leukemia Patients in Egypt

Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Chronic Phase

Egypt
Center for Reproductive an Genetic Health

Unknown

The Effectiveness of Blastocentesis Versus Trophectoderm Biopsy

Abnormal Karyotype

United Kingdom
Instituto Valenciano de Infertilidad, IVI VALENCIA

Terminated

Embryo Aneuploidies and Morphokinetics in Ovarian Stimulated and Non Stimulated IVF Cycles (AMOS)

Euploid Embryos

Spain
Cindy Cisneros

Completed

Development of a Prenatal Test for Fetal Aneuploidy Detection

Fetal Complications

United States
Reproductive Endocrinology Associates of Charlotte

Completed

Aneuploidy Rates in Advanced Maternal Age Patients Supplemented With Coenzyme Q10 (CoQ10) Versus Those That Are Not: a Pilot Study

Aneuploidy | Mitochondrial DNA

United States
IVI Madrid

Terminated

Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

Aneuploidy Rate

Spain
National Eye Institute (NEI)

Completed

Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure

Menopause | Turner Syndrome | Ovarian Failure, Premature | Sex Chromosome Aberrations | Perimenopause

United States
University of Washington
Incyte Corporation

Recruiting

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

ALL, Adult | Philadelphia-Positive ALL | Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)

Italy
Boston Children's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Intellectual Disability | Autism Spectrum Disorder | Phelan-McDermid Syndrome

United States
Novartis Pharmaceuticals

Active, not recruiting

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

United States, China, Hungary, Japan, Belgium, Germany, Canada, Singapore, Australia, Israel, Netherlands, Spain, Italy, Korea, Republic of, Bulgaria, France, United Kingdom, Czechia, Sweden, India, Malaysia, Denmark, Taiwan, Norway, Fi... and more
Icahn School of Medicine at Mount Sinai
National Institute of Neurological Disorders and Stroke (NINDS)

Enrolling by invitation

A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

Autism Spectrum Disorder (ASD) | Phelan-McDermid Syndrome

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Active, not recruiting

Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia (LAL2317)

Acute Lymphoid Leukemia | Philadelphia Chromosome-Negative B-Cell Precursor

Italy
Thomas Jefferson University
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Androgen Effect on Klinefelter Syndrome Motor Outcome

Klinefelter Syndrome

United States
University of Colorado, Denver

Completed

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

Klinefelter Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Multicenter Trial Treatment of Philadelphia Chromosome Negative B-cell Acute Lymphoblastic Leukemia of Young Adults (GRAALL-2014/B)

Philadelphia Chromosome Negative Adult B-cell Acute Lymphoblastic Leukemia

France
Boston Children's Hospital
Phelan-McDermid Syndrome Foundation

Completed

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Intellectual Disability | Autism Spectrum Disorder | Phelan-McDermid Syndrome

United States
Antonio Persico
University of Bari; Associazione Italiana Sindrome di Phelan-McDermid (AISPHEM)

Enrolling by invitation

Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome. (Q10ASD)

Autism Spectrum Disorder | Phelan-McDermid Syndrome

Italy
Hospices Civils de Lyon

Completed

Fertility Preservation in Cases of Klinefelter Syndrome. (FERTIPRESERVE)

Klinefelter Syndrome

France
University of Pittsburgh

Terminated

Fertility Assessment in Patients With Klinefelter Syndrome

Klinefelter Syndrome

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen

Completed

Subcapsular Orchiectomy in Men With Klinefelter Syndrome

Klinefelter Syndrome

Denmark
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Singapore, France, Germany, United Arab Emirates, Greece, Italy, Czechia, Hungary, United States, India, Oman, Malaysia, Korea, Republic of, Turkey, Bulgaria, Canada, Slovakia, United Kingdom, Argentina, Jordan, Romania, South Africa and more
Crystal Mackall, MD
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Minimal Residual Disease | CD19 Positive

United States
University of Colorado, Denver
National Institute of Neurological Disorders and Stroke (NINDS); Children's... and other collaborators

Completed

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome (TestoXXY/KS)

Klinefelter Syndrome | XXY Syndrome

United States
University of Colorado, Denver
Children's Hospital Colorado

Recruiting

Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY) (GALAXY)

Sex Chromosome Aneuploidy

United States
Clinique Ovo

Active, not recruiting

DFI and Aneuploidies

Embryo Disorder

Canada
Premaitha Health

Completed

A Safer Pre-Natal Diagnosis Using Free DNA in Maternal Blood (IONA)

Aneuploidy, NIPT

United Kingdom
Wayne State University

Unknown

Prenatal Computer-Aided Genetics Education Module (CAGEM)

Aneuploidy | Autosomal Recessive Disorder

United States
Nordic MDS Group

Completed

Lenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5

AML | MDS

Denmark, Norway, Sweden
RIVAGES

Not yet recruiting

Usefulness of the Medissimo Nurse Application for Supporting Medication Compliance in Elderly People With Chronic Polypathologies

Chronic Disease | Medication Compliance | Polypathology | Elderly Person | Digital Application
Eyup Hakan Duran

Recruiting

Preimplantation Genetic Testing for Aneuploidy Counseling (PGT-A)

Patient Education

United States
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; Juno Therapeutics, Inc.

Not yet recruiting

Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications

Embryo Disorder
The University of Hong Kong

Recruiting

RCT of niPGT for Aneuploidy and Morphology Compared With Morphology Alone in IVF

Preimplantation Diagnosis

China
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Embryo Aneuploidies and Ovarian Stimulation

Embryo Aneuploidies

Spain
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Peking University People's Hospital and other collaborators

Unknown

Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML

MRD | Risk-directed Therapy | Cytogenetic Abnormality | Molecular Abnormality

China
Trakya University

Completed

The Effect of Using Interactive Mobile Application for the Management of Chemotherapy- Induced Nausea and Vomiting in Children

Pediatric Cancer | Oncology | Mobile Application | Nausea and Vomiting Chemotherapy-Induced

Turkey
Duzce University

Not yet recruiting

The Effect of Cold Application on the Hemostasis, Extremity Pain And Terumo Band Usage After Transradial Angiography

Pain | Hemostasis | Radial Artery | Angiography | Local Application / Packing Too Cold

Clinical Trials on Chromosome 15q Duplication

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