Clinical Trials on Chronic Illnesses

Total 34372 results

University of Colorado, Denver

Active, not recruiting

Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy

Gastroparesis | Zenker's Diverticulum | Hirschsprung's Disease | Esophageal Obstruction | Gastrointestinal Neoplasia | Spastic Esophageal Disorders

United States
Sidekick Health
Landspitali University Hospital; Ljósið Cancer Rehabilitation Center

Active, not recruiting

A Digital Therapeutic Solution for Cancer Patients

Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer

Iceland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

EGFR NP_005219.2:p.S492R | KRAS Gene Mutation | MAP2K1 Gene Mutation | Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7

United States
Nitto BioPharma, Inc.

Active, not recruiting

A Study of NBF-006 in Non-Small Cell Lung, Pancreatic, or Colorectal Cancer

Colorectal Cancer | Pancreatic Cancer | Non-Small Cell Lung Cancer

United States
Janssen Scientific Affairs, LLC

Completed

A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL)

Hepatosplenic T-Cell Lymphoma

United States
Janssen Research & Development, LLC

Completed

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

Neoplasms | Colorectal Cancer | Advanced Solid Tumors | Non-small Cell Lung Cancer

France, United States
King's College London

Completed

Management and Outcomes of Congenital Anomalies in Low-, Middle- and High-Income Countries

Congenital Diaphragmatic Hernia | Gastroschisis | Intestinal Atresia | Hirschsprung Disease | Oesophageal Atresia | Anorectal Malformation | Exomphalos

United Kingdom
The Netherlands Cancer Institute
AstraZeneca; Boehringer Ingelheim

Unknown

Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer (M14AFS)

Gastrointestinal Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms

Netherlands
Viatar LLC
Commonwealth Hematology-Oncology, P.C.

Completed

Collection of Blood Specimens for Circulating Tumor Cell Analysis

Breast Cancer | Colorectal Cancer | Prostate Cancer

United States
Vifor Pharma
Parexel; ClinStar, LLC

Completed

FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR (FER-IBD-COR)

Anemia | Crohn's Disease | Ulcerative Colitis | Iron Deficiency | Inflammatory Bowel Disease | Iron-Deficiency Anemia

Austria
Oslo University Hospital

Terminated

Coxib-inhibition of Duodenal Polyp Growth in FAP

Duodenal Polyposis

Norway
The Cleveland Clinic

Recruiting

Vascular Lab Resource (VLR) Biorepository

Cardiovascular Diseases | Lymphedema | Thrombosis | Vasculitis | Peripheral Artery Disease | Metabolic Disease | Lipedema | Thoracic Outlet Syndrome | Vasospasm | Venous Disease | Fibromuscular Dysplasia | May-Thurner Syndrome | Carotid Disease | Aneurysmal Disease | Non-Atherosclerotic Chronic Arterial Occlusive Disease and other conditions

United States
The Immunobiological Technology Institute (Bio-Manguinhos)...
Oswaldo Cruz Foundation

Recruiting

Gene Sequencing as a Strategy for Identifying Genetic Factors Associated With Serious Adverse Events After Covid-19 Vaccines in Use in Brazil

Guillain-Barre Syndrome | Transverse Myelitis | Acute Disseminated Encephalomyelitis | Vaccine-induced Thrombotic Thrombocytopenia Syndrome

Brazil
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Alabama at Birmingham
Lakeshore Foundation; YMCA of Greater Birmingham

Active, not recruiting

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study (M2M LEADERS)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Traumatic Brain Injury | Spinal Cord Injuries | Spina Bifida

United States
Sanko University

Completed

Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns (therapy)

Preterm Birth | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Mechanical Ventilation Complication | Chronic Liver Disease | Hyaline Membrane Disease | Premature | Oxygen Toxicity | Neonatal Respiratory Failure | Atelectasis Neonatal | Mechanical Ventilation Pressure High | Pneumonia Neonatal | Lobar...

Turkey
Gillette Children's Specialty Healthcare

Completed

Effects of Standing on Non-Ambulatory Children With Neuromuscular Conditions

Cerebral Palsy | Muscular Dystrophy | Osteopenia | Rett Syndrome | Spinal Muscular Atrophy | Spina Bifida

United States
NCIC Clinical Trials Group

Completed

Treatment for Chronic Pain in Patients With Advanced Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

Canada
Robert Lowsky
National Cancer Institute (NCI)

Completed

A Phase I/II Study of Intratumoral Injection of SD-101

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic...

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

American Ginseng in Treating Patients With Fatigue Caused by Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Fatigue | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Cancer Institute (NCI)

Terminated

Obatoclax and Bortezomib in Treating Patients With Aggressive Relapsed or Recurrent Non-Hodgkin Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma | Adult Non-Hodgkin Lymphoma

United States
National Cancer Institute (NCI)

Completed

Rituximab and Interleukin-12 in Treating Patients With B-Cell Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Small Lymphocytic Lymphoma

United States
Motric Bio

Recruiting

Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals

Stroke | Multiple Sclerosis | Cerebral Palsy | Spinal Cord Injuries | Dystonia | Muscle Spasticity | Hereditary Spastic Paraplegia | Hypertonia, Muscle

United States
Karolinska Institutet
Karolinska University Hospital; Pfizer

Recruiting

imPROving Quality of LIFe In the Long COVID Patient (PROLIFIC)

COVID-19 | Post-COVID-19 Syndrome | Long COVID | Long Covid19 | Post COVID-19 Condition | Post-COVID Syndrome | Post COVID-19 Condition, Unspecified | POTS - Postural Orthostatic Tachycardia Syndrome | Postinfectious Inflammation | Postinfectious Disorder

Sweden
Perspectum

Recruiting

Repeatability and Reproducibility of Multiparametric MRI

Liver Diseases | Cirrhosis | Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Hemochromatosis | Non-Alcoholic Fatty Liver Disease | Non-Alcoholic Steatohepatitis | Primary Biliary Cirrhosis | Viral Hepatitis

Netherlands, United Kingdom
Stanford University
The Marfan Foundation

Active, not recruiting

Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions

Chronic Pain | Marfan Syndrome | Vascular Ehlers-Danlos Syndrome | Loeys-Dietz Syndrome

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Psychosocial Effects of Cancer and Its Treatment | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Indiana University School of Medicine
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Locally Advanced or Metastatic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
Amir Mortazavi
National Cancer Institute (NCI); Arno Therapeutics

Completed

AR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lymphoma

Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; Syntrix Biosystems, Inc.

Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment

Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Stage IIA Rectal Cancer AJCC... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer

Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage... and other conditions

United States
University of California, San Francisco
Bristol-Myers Squibb; Pfizer

Terminated

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Terminated

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC... and other conditions

United States
Sichuan University

Not yet recruiting

Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors

Melanoma | Carcinoma | Colorectal Cancer | Bladder Cancer

China
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab

Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Gastroesophageal Adenocarcinoma

United States, Japan, Puerto Rico, Taiwan, Spain, Australia, France, Israel, Korea, Republic of, Poland
Karyopharm Therapeutics Inc

Recruiting

Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment (SPRINT)

Other Solid Tumors | Colorectal Cancer (CRC) | Non-Small Cell Lung Carcinoma (NSCLC)

Israel
Seoul National University Hospital
Ministry of Health, Republic of Korea

Completed

Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients

Insomnia | Low Anterior Resection Syndrome | Rectal Cancer

Korea, Republic of
Eli Lilly and Company

Completed

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

Colorectal Cancer | Metastatic Melanoma | Advanced Cancer | Metastatic Non-small Cell Lung Cancer

United States, Japan, Australia, France
Massachusetts General Hospital

Completed

Improving Care After Chemotherapy (IMPACT)

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer

United States
KU Leuven

Unknown

Collaborative Network to Take Responsibility for Oral Anticancer Therapy (CONTACT)

Melanoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | ALL

Belgium
W.L.Gore & Associates

Terminated

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

Rectal Cancer | Ulcerative Colitis | Familial Adenomatous Polyposis | Diverticulitis

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis (EHEC-PEG)

Hemolytic Uremic Syndrome | Hemorrhagic Colitis | Intestinal Infectious Disease | Intestinal Infection Due to E. Coli

Germany
Wuhan University
NPO Organization to Support Peritoneal Dissemination Treatment; Kishiwada Tokushukai... and other collaborators

Unknown

Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis (IPHC)

Stomach Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms | Mesothelioma

China
Oncology Institute of Vojvodina
University of Bern

Not yet recruiting

Iron-deficiency Anaemia and Its Impact on Recovery After Colorectal Cancer Surgery (ID-COLO)

Postoperative Complications | Colorectal Cancer | Iron Deficiency Anaemia | Iron Deficiencies
UNICANCER
Servier

Not yet recruiting

Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer (TRIFLUOX-DP)

Metastatic Colorectal Cancer | Metastatic Gastroesophageal Adenocarcinoma | DPD Deficiency

Clinical Trials on Chronic Illnesses

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations