Clinical Trials on Cocaine Abuse and Dependence

Total 3449 results

Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Active, not recruiting

rTMS for Stimulant Use Disorders (CTN-0108)

Methamphetamine Use Disorder | Cocaine Use Disorder | Cocaine Dependence | Methamphetamine Dependence | Stimulant Use Disorder | Methamphetamine Abuse | Cocaine Abuse | Stimulant Abuse | Stimulant Use

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Rivastigmine and Huperzine A as Treatments for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Modafinil - Escitalopram Study for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Completed

Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals

Opioid-Related Disorders | Heroin Dependence | Cocaine Abuse or Dependence

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Pramipexole as a Treatment for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Exercise as a Behavioral Treatment for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Recruiting

Substance Abuse Pre-Treatment Screening Study

Alcohol Dependence | Substance Abuse | Cocaine Dependence | Opiate Dependence | Cocaine Abuse

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Completed

Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) (ARC)

Opioid-Related Disorders | Heroin Dependence | Cocaine Abuse or Dependence

United States
US Department of Veterans Affairs

Completed

Use of Donepezil for Treatment of Cocaine Dependence

Cocaine Abuse and Dependence

United States
Seattle Institute for Biomedical and Clinical Research
AstraZeneca; VA Puget Sound Health Care System

Completed

Quetiapine for the Reduction of Cocaine Use (AZC)

Substance Abuse | Cocaine Dependence | Drug Abuse | Cocaine Abuse | Cocaine Addiction

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Abstinence-Linked Money Management Multisite

Dual Diagnosis | Cocaine Dependence | Polysubstance Abuse | Cocaine Abuse

United States
Temple University
National Institute on Drug Abuse (NIDA); University of Pennsylvania

Completed

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

Cocaine-Related Disorders | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
University of Southern California
National Institute on Drug Abuse (NIDA); University of Toronto; RTI International

Completed

Change the Cycle: An RCT to Prevent Injection Initiation (CTC)

Substance Abuse, Intravenous | HIV | Heroin Dependence | Opioid Dependence | Cocaine Dependence | Amphetamine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Progesterone for Postpartum Cocaine Relapse

Cocaine Dependence | Cocaine Abuse

United States
ITAB - Institute for Advanced Biomedical Technologies

Not yet recruiting

Effect of rTMS on Neurotrophines Levels in CUD (BDNFcoca)

Cocaine Dependence | Cocaine Use | Cocaine Abuse | Neurotropism

Italy
Treatment Research Institute

Completed

Long Term Maintenance of Drug Abstinence

Cocaine Dependence | Cocaine Abuse

United States
University of Kentucky
National Institute on Drug Abuse (NIDA)

Completed

n-Acetylcysteine and Cocaine

Cocaine Dependence | Cocaine Abuse

United States
University of Pittsburgh
Indiana University of Pennsylvania

Completed

The Effect of Self-Forgiveness on Self-Stigma in Addiction.

Substance Use Disorders | Benzodiazepine Dependence | Alcohol Use Disorder | Substance Abuse | Opioid-use Disorder | Cocaine Use Disorder | Alcohol Abuse | Opiate Dependence | Alcohol Withdrawal | Benzodiazepine Abuse | Cocaine Abuse | Heroin Abuse | Cocaine Withdrawal | Opiate Withdrawal Syndrome | Heroin Overdoses | Heroin...

United States
Johns Hopkins University

Completed

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

Behavior, Addictive | Heroin Dependence | Opioid Dependence | Cocaine Dependence | Cocaine Abuse

United States
University of Virginia

Recruiting

Low-Intensity Focused Ultrasound for Cocaine Use Disorder

Cocaine Use Disorder | Cocaine Dependence | Ultrasound | Cocaine Abuse

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center
VA Mental Illness Research, Education and Clinical Centers

Completed

Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting

Cannabis Dependence | Opioid-use Disorder | Cocaine Use Disorder | Cocaine Dependence | Opiate Dependence

United States
Wayne State University

Completed

Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC) (NAC)

Cocaine Abuse or Dependence | Cocaine Related Disorders

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Completed

Non-Treatment Study of Factors Affecting Cocaine Drug Choice (CTA)

Cocaine Abuse or Dependence | Cocaine Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Effect of Clonidine on Responses to Imagery Scripts

Cocaine Abuse | Heroin Abuse

United States
National Institute on Drug Abuse (NIDA)
University of Maryland

Completed

Risk Perception in Drug-Dependent Adults With and Without Schizophrenia

Schizophrenia | Cannabis Dependence | Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)
Yale University

Completed

The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1

Substance-Related Disorders | Contingency Management | Heroin Dependence | Opioid Dependence | Behavior Therapy | Alcohol & Drug Use | Cocaine | LAAM

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence

Substance Abuse | Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)

Completed

Reward Processing in Cocaine Addiction

Cocaine Dependence | Drug Abuse

United States
National Institute on Drug Abuse (NIDA)

Terminated

Brain Glutamate Receptors and Cocaine Dependence

Cocaine Dependence | Drug Abuse

United States
Sharon Walsh
National Institute on Drug Abuse (NIDA); Eli Lilly and Company

Completed

Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial

Substance Abuse

United States
National Institute on Drug Abuse (NIDA)

Completed

PET Assays of Striatal Dopamine Marker in Cocaine Craving

Cocaine Dependence | Drug Abuse | Neural Systems

United States
Treatment Research Institute
National Institute on Drug Abuse (NIDA)

Completed

Contingency Management for Cocaine Dependence: Cash Versus Vouchers

Substance Abuse | Substance Related Disorders | Drug Addiction

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Disulfiram for Cocaine Abuse in Buprenorphine Treatment

Opioid Dependency | Cocaine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients (Keppra-DB)

Opioid Dependency | Cocaine Dependence

United States
Temple University
National Institute on Drug Abuse (NIDA)

Completed

Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid (CLAVMRPilot)

Cocaine-Related Disorders | Cocaine Dependence, in Remission | Cocaine Abuse, in Remission

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA); University of Texas

Terminated

Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

Opiate Dependence | Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)

Completed

Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse

Opioid Dependence | Cocaine Abuse
University of Texas Southwestern Medical Center

Completed

Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence

Mania | Cocaine Dependence | Cocaine Abuse | Hypomania

United States
W. Michael Hooten
National Institute on Drug Abuse (NIDA)

Recruiting

AAV8-hCocH for Cocaine Use Disorder

Cocaine Dependence, in Remission

United States
Catalyst Pharmaceuticals, Inc.

Completed

A Safety, Tolerability and Pharmacokinetic Study of CPP-115

Cocaine Dependency

United States
Duke University

Completed

An Opioid Prescribing Nudge (OHS)

Health Behavior | Opioid Use, Unspecified | Benzodiazepine Abuse | Prescription Drug Abuse (Not Dependent) | Benzodiazepine Dependent | Prescription Drug Abuse and Dependency

United States
University of Arkansas
National Institute on Drug Abuse (NIDA); Baylor College of Medicine

Completed

Doxazosin for Psychostimulant Dependence

Methamphetamine or Cocaine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of Extended Treatments for Drug Dependence (ETDD)

Cocaine Dependence

United States
Tong Lee
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin®)(OND003IND)

Cocaine Dependence | Methamphetamine Dependence

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Smoking-Cessation and Stimulant Treatment (S-CAST) (S-CAST)

Nicotine Dependence | Cocaine Dependence | Methamphetamine Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Therapeutic Substance Abuse Treatment in Pregnancy - 1 (PRIDE-P)

Marijuana Abuse | Alcohol Abuse | Cocaine Abuse

United States
University of Pennsylvania

Completed

Effectiveness of Extended Treatment for Drug Dependence (ETDD) in the City Study

Cocaine Dependence

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Employment-based Reinforcement of Naltrexone Ingestion and Abstinence

Substance Abuse, Intravenous | Opioid-Related Disorders | Heroin Dependence | Cocaine-Related Disorders

United States

Clinical Trials on Cocaine Abuse and Dependence

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CROs in Malta

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