Clinical Trials on Cocaine-Related Disorders

Total 161478 results

Nantes University Hospital
National Research Agency, France

Completed

Pathological Findings of Fatal COVID-19 (HISTOCOVID)

Covid19 | Respiratory Distress Syndrome | SARS-CoV-2 | Intensive Care Units | Pathology

France
University of Michigan
Charite University, Berlin, Germany; Heinrich-Heine University, Duesseldorf; University... and other collaborators

Completed

International Study of Inflammation in COVID-19 (ISIC)

Inflammation | Covid19 | Respiratory Failure | Acute Kidney Injury | Outcome, Fatal

United States
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
Inmunova S.A.
Linical Co., Ltd.; KLIXAR; PHV LATAM

Completed

A Study to Assess Safety, Efficacy, and Pharmacokinetics of INM004 in Pediatric Patients With STEC-HUS

Hemolytic-Uremic Syndrome | Pediatric Kidney Disease | Diarrhea-Associated Hemolytic Uremic Syndrome

Argentina
Vanderbilt University Medical Center
Aminu Kano Teaching Hospital

Active, not recruiting

Stroke Prevention in Young Adults With Sickle Cell Anemia (SPIYA)

Stroke | Sickle Cell Disease | Sickle Cell Anemia | Stroke, Ischemic | Silent Cerebral Infarct | Silent Stroke

Nigeria, United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
Guangdong Provincial People's Hospital

Withdrawn

Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor (CoVac-Lung)

Vaccine Adverse Reaction | Lung Cancer | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

China
APR Applied Pharma Research s.a.

Withdrawn

Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 (AVICOVID-3)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI
University Hospital, Ghent

Completed

Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System

ARDS (Acute Respiratory Distress Syndrome) | Respiratory Acidosis

Belgium
University Hospital, Ghent

Completed

Veno-venous Extracorporeal CO2 Removal in ARDS-patients to Treat Respiratory Acidosis

ACUTE RESPIRATORY DISTRESS SYNDROME

Belgium
University of Pennsylvania

Completed

Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor (NNOM)

Ischemic Stroke | Traumatic Brain Injury | Subarachnoid Hemorrhage | Intracerebral Hemorrhage | Acute Anoxic Encephalopathy

United States
International Centre for Diarrhoeal Disease Research...
University of Edinburgh; Dhaka Medical College

Completed

Treatment of COVID-19 Positive/Negative Bangladeshi Adults With Severe Respiratory Complaints by a Locally Made bCPAP: Feasibility Study (Adult-bCPAP)

Covid19 | Acute Respiratory Distress Syndrome | Severe Pneumonia

Bangladesh
Goethe University

Completed

Prospective Electroencephalography Evaluation of Sedation in COVID-19

Pathologic Processes | Acute Respiratory Distress Syndrome | Corona Virus Infection | Electroencephalogram | Conscious Sedation

Germany
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Kinevant Sciences GmbH
Roivant Sciences, Inc.

Completed

A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)

COVID-19

United States
Roswell Park Cancer Institute

Completed

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

United States
University of Alabama at Birmingham
Medtronic; The Children's Tumor Foundation

Terminated

A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1) (NF107-BMP2)

NF1 | Congenital Pseudarthrosis of Tibia

United States, Australia
Centro de Educación Medica e Investigaciones Clínicas...

Terminated

Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial

Covid-19 | Respiratory Distress Syndrome, Adult

Argentina
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury

Shock | Head Injuries, Closed | Respiratory Distress Syndrome, Adult | Shock, Traumatic

United States
Manchester University NHS Foundation Trust
Manchester Metropolitan University

Completed

Whole-body Vibration in Children With Neurofibromatosis Type 1

Muscle Weakness | Neurofibromatosis Type 1

United Kingdom
University Hospital, Lille

Completed

Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome (PrediLynch)

Lynch Syndrome

France
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction

Acute Respiratory Distress Syndrome (ARDS) | Acute Lung Injury (ALI)

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19 (COVID-19)

Covid 19

Mexico
Joanne Jeter
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Lynch Syndrome | Colon Adenoma | Colon Carcinoma | MLH1 Gene Mutation | MSH2 Gene Mutation

United States
AstraZeneca

Approved for marketing

An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1

NF type1 With Inoperable Plexiform Neurofibromas

United States
Royan Institute
Tehran University of Medical Sciences; Shahid Beheshti University of Medical...

Unknown

Mesenchymal Stem Cell Therapy for SARS-CoV-2-related Acute Respiratory Distress Syndrome

Covid-19

Iran, Islamic Republic of
National Institute of Neurological Disorders and...

Completed

Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy

Motor Neuron Disease

United States
Tufts Medical Center
Brigham and Women's Hospital; Poznan University of Medical Sciences; Baystate... and other collaborators

Completed

Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome in Premature Infant

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Withdrawn

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure (IPGE1)

Streptococcal Infections | Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
Mahidol University

Completed

The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium

Paralysis | Critical Illness | Respiratory Failure | Respiratory Distress Syndrome, Adult | Neuromuscular Blockade | ARDS, Human

Thailand
Amazon University
Santa Casa de Misericórdia do Pará

Completed

Correlation of Survival in Puerperae by Electrical Impedance Tomography (COSIPBEIT)

Sepsis | HELLP Syndrome | Postpartum Period | Respiratory Distress Syndrome,Adult
Johns Hopkins University
University of North Carolina, Chapel Hill; Children's Hospital Medical Center... and other collaborators

Terminated

CPAP Improving Mortality for Pneumonia in African Children Trial (IMPACT)

Pneumonia | Malnutrition | Hypoxemia | Human Immunodeficiency Virus (HIV)

Malawi
University Hospital, Bordeaux

Completed

Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers (STBETA)

Tuberous Sclerosis | Renal Angiomyolipomas

France
Instituto Aragones de Ciencias de la Salud

Unknown

Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins

Arteriosclerosis | Aortic Stenosis | Familial Hypercholesterolemia | Conventional Transthoracic Echocardiogram

Spain
NICHD Neonatal Research Network
National Center for Research Resources (NCRR); Medical Research Council of...

Terminated

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns (NINOS)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States, Canada
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Hoffmann-La Roche
Association Française contre les Myopathies (AFM), Paris

Completed

Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type III Non Ambulant

Germany, Italy, France, Belgium, Poland, Netherlands, United Kingdom
Odense University Hospital

Completed

Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke

Ischemic Stroke | Paroxysmal Atrial Fibrillation | Premature Atrial Complexes

Denmark
VA Office of Research and Development

Completed

Outlook Quality of Life Intervention Study

Cancer | Chronic Obstructive Pulmonary Disease (COPD) | End Stage Renal Disease (ESRD) | Congestive Heart Failure (CHF)

United States
Washington University School of Medicine

Completed

Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome

HIV Infections | Metabolic Syndrome | HIV (Human Immunodeficiency Virus)

United States
Cooperative International Neuromuscular Research...
Carolinas Medical Center lead study site

Completed

Evaluation of Limb-Girdle Muscular Dystrophy

Becker Muscular Dystrophy | Limb-Girdle Muscular Dystrophy, Type 2A (Calpain-3 Deficiency) | Limb-Girdle Muscular Dystrophy, Type 2B (Miyoshi Myopathy, Dysferlin Deficiency) | Limb-Girdle Muscular Dystrophy, Type 2I (FKRP-deficiency)

United States
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research...

Completed

Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)

Hematologic Diseases | Iron Overload | Hypertension, Pulmonary | Osteoporosis | Thalassemia | Beta-Thalassemia | Anemia, Cooley's

United States, Canada
Genzyme, a Sanofi Company

Approved for marketing

Alglucosidase Alfa Temporary Access Program (ATAP)

Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease (Late-Onset)

United States
Xiangya Hospital of Central South University

Completed

Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS

Bronchopulmonary Dysplasia | Nasal Continuous Positive Airway Pressure, | Preterm Infants, | Surfactant Treatment, | Respiratory Distress Syndrome,
Novartis

Completed

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Pain | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Hypercalcemia of Malignancy

United States
The University of Texas Health Science Center at...
Sanchez Cancer Center

Terminated

Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia

Neoplasm Metastasis | Lung Cancer | Bone Cancer | Prostate Cancer

United States
Johann Wolfgang Goethe University Hospital

Unknown

Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) (GHAT)

Growth Failure | Ataxia Telangiectasia

Germany
VM Oncology, LLC

Recruiting

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Sarcoma | Cervical Cancer | Breast Cancer | Adenoid Cystic Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Thymic Carcinoma | Lung Cancer | Mesothelioma | Bladder Cancer | Head and Neck Carcinoma | Uterine Cancer | Any Solid Tumors Progressed After a Prior Immunotherapy

United States, Puerto Rico
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia

Clinical Trials on Cocaine-Related Disorders

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