Clinical Trials on Coinfection in South Africa

Total 738 results

Melinta Therapeutics, Inc.

Completed

A Study to Assess Objective Endpoint Measurements of Response in Bacterial Skin Infections

Skin and Subcutaneous Tissue Bacterial Infections

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus Rilpivirine

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Canada
AlloVir

Completed

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

BK Virus Infection | BK Virus Nephropathy

United States
Gen-Probe, Incorporated

Terminated

Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays

Gonorrhea | Chlamydia Infections | Trichomonas Infections

United States
Boehringer Ingelheim

Approved for marketing

Tipranavir Expanded Access Program (EAP) in PI-experienced Patients With HIV-1 Infection

HIV Infections

United States
AstraZeneca

Completed

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY) (MELODY)

Respiratory Syncytial Virus Infections

United States, Finland, Spain, Belgium, France, Korea, Republic of, Turkey, Austria, New Zealand, South Africa, Australia, Germany, Bulgaria, United Kingdom, Ukraine, Argentina, Czechia, Panama, Estonia, Lithuania, Poland, Japan, Co... and more
Regeneron Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Suptavumab (REGN2222) for the Prevention of Medically Attended RSV (Respiratory Syncytial Virus) Infection in Preterm Infants

Respiratory Syncytial Virus Infections

United States, Australia, Bulgaria, Canada, Chile, Denmark, Finland, Germany, Hungary, Netherlands, New Zealand, Panama, Puerto Rico, South Africa, Spain, Sweden, Turkey, Ukraine, United Kingdom
Shionogi

Recruiting

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection (SCORPIO-PEP)

SARS-CoV-2 Infection

Japan, United States
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group; Acute Infection and Early Disease Research Program

Completed

Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection

HIV Infections

United States, American Samoa, Australia
Research Institute for Genetic and Human Therapy

Completed

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults

HIV Infections

United States
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

Healthy Volunteers (Meningococcal Infection)

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive Medications

HIV Infections

United States, Puerto Rico
GOG Foundation
National Cancer Institute (NCI)

Active, not recruiting

CA-IX, p16, Proliferative Markers, and HPV in Diagnosing Cervical Lesions in Patients With Abnormal Cervical Cells

Atypical Endometrial Hyperplasia | Human Papillomavirus Infection | Stage 0 Cervical Cancer AJCC v7

United States, Korea, Republic of, Japan
Dipexium Pharmaceuticals, Inc.

Completed

Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers (OneStep-2)

Diabetic Foot Infection

United States
PharmaResearch

Unknown

Comparing Side Effects of Two Forms of Videx in HIV-Infected Adults

HIV Infections

United States
ViiV Healthcare

Recruiting

A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories (EBONI)

HIV Infections

United States
Gilead Sciences

Completed

Efficacy And Safety Of Sofosbuvir/Velpatasvir Fixed Dose Combination With Ribavirin in Chronic HCV Infected Adults Who Participated in a Prior Gilead Sponsored HCV Treatment Study

Hepatitis C Virus Infection

United States, New Zealand, Puerto Rico, Australia
Paratek Pharmaceuticals Inc

Completed

Oral Omadacycline vs. Oral Linezolid for the Treatment of ABSSSI

Bacterial Infections | Skin Structures and Soft Tissue Infections

United States
Gilead Sciences

Terminated

GS-5885, GS-9451 With Peginterferon Alfa 2a (PEG) and Ribavirin in Treatment-Naïve Subjects With Chronic Genotype 1 Hep C Virus Infection and IL28B CC Genotype

Chronic Hepatitis C

United States, Australia, Canada, New Zealand
Pfizer

Completed

Clostridium Difficile Vaccine Efficacy Trial (Clover)

Clostridium Difficile Infection

United States, Spain, Belgium, Taiwan, Japan, Portugal, Colombia, Korea, Republic of, Poland, Australia, Germany, Canada, Argentina, Bulgaria, Chile, Czechia, Finland, France, Hungary, Peru, Slovakia, Sweden, United Kingdom
Gilead Sciences

Terminated

A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection

Hepatitis C Virus Infection

France, Spain, United States, Australia, Canada, Germany, United Kingdom, Italy, New Zealand, Puerto Rico
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004)

Respiratory Syncytial Virus Infection

United States, Argentina, Belgium, Canada, Chile, China, Colombia, Denmark, Finland, France, Israel, Italy, Japan, Korea, Republic of, Malaysia, Mexico, Peru, Philippines, Poland, Romania, South Africa, Thailand, Turkey, United Kingdom
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

Clostridium Difficile Infection

United States, Australia, Brazil, Canada, France, Germany, Italy, Netherlands, Peru, Poland, Romania, Spain
Insmed Incorporated

Completed

Safety/Tolerability Study of Arikayce™ in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas Aeruginosa

Cystic Fibrosis

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Diarrhea | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Bacterial Infection | Acute Leukemias of Ambiguous Lineage | Musculoskeletal Complications | Untreated Childhood Acute Myeloid Leukemia...

United States, Canada
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Recruiting

Outpatient Treatment With Anti-Coronavirus Immunoglobulin (OTAC)

Covid19 | COVID | SARS-CoV2 Infection

United States, Spain, Argentina, Denmark, Greece, India, Mexico, Uganda
National Institute of Allergy and Infectious Diseases...
Lederle Laboratories; Hoechst Marion Roussel

Completed

Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection

HIV Infections | Tuberculosis

United States, Puerto Rico
Gilead Sciences

Terminated

Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria (ALPINE 2)

Cystic Fibrosis | Pseudomonas Aeruginosa Respiratory Tract Infection/Colonization

United States, Spain, United Kingdom, Denmark, Belgium, France, Italy, Germany, Israel, Netherlands, Austria, Greece
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Jiangsu ProteLight Pharmaceutical & Biotechnology...
Parexel

Not yet recruiting

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers (PL-5)

Diabetic Foot Ulcers

United States
Novartis
Novartis Vaccines

Completed

Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants

Meningitis | Meningococcal Infection

United States, China, Costa Rica, Guatemala, Panama, Peru
Merck Sharp & Dohme LLC

Recruiting

A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013) (STRIDE-13)

Pneumococcal Infection

France, United States, Japan, Canada, Turkey, Finland, Spain, Poland, Sweden, Chile, Colombia, Israel
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis

Aspergillosis | Invasive Fungal Infection

Korea, Republic of, Belgium, Australia, United States, Germany, Switzerland, Israel, Canada, Argentina, Chile, Malaysia, Thailand, France, Russian Federation, Hungary, Spain, Brazil, China, India, Egypt, Italy, Turkey, Netherlands, Me... and more
Critical Care Pharmacotherapy Trials Network
University of Arkansas

Completed

Drug Resistance Factors In Healthcare-associated Pneumonia (DEFINE)

Pneumonia | Critical Illness

United States, Saudi Arabia
Pfizer

Completed

Skin Structure Infections With Suspected or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA)

Skin/Soft Tissue Infections | Methicillin Resistant Staphylococcus Aureus (MRSA)

United States, Spain, United Kingdom, Colombia, Italy, Chile, Argentina, Mexico, Belgium, Russian Federation, Brazil, Malaysia, Singapore, Portugal, South Africa, Venezuela
Biota Scientific Management Pty Ltd

Completed

A Phase 2 Study of BTA798 in Asthmatic Adults With Symptomatic Human Rhinovirus Infection (RHINO)

Rhinovirus

United States
BioNTech SE
Pfizer

Active, not recruiting

A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals

COVID-19 | SARS-CoV-2 Infection

United States
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)

Nosocomial Pneumonia

United States, Estonia, Greece, Spain, Ukraine, Chile, Russian Federation, Colombia, Mexico
AN2 Therapeutics, Inc

Active, not recruiting

Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease

MAC Lung Disease | Treatment Refractory MAC Lung Disease

United States, Australia, Japan, Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection

HIV Infections | Cytomegalovirus Infections | Pneumonia, Pneumocystis Carinii | Cytomegalovirus Retinitis

United States
Pfizer

Completed

Nosocomial Pneumonia With Suspected Or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA) (ZEPHYR)

Methicillin Resistant Staphylococcus Aureus (MRSA)

United States, Greece, Colombia, Korea, Republic of, Russian Federation, Turkey, Brazil, Chile, Taiwan, Mexico, Belgium, Spain, Hong Kong, Puerto Rico, France, United Kingdom, Malaysia, Germany, South Africa, Portugal, Argentina, ...
Gilead Sciences

Approved for marketing

Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Airway Infection

Cystic Fibrosis | Pseudomonas Aeruginosa Airway Infection

United States, Puerto Rico
AbbVie

Completed

A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-I)

Chronic Hepatitis C Virus (HCV) Infection Genotype 1

Algeria, Australia, Belgium, Bulgaria, Canada, Denmark, Finland, France, Germany, Greece, Israel, Italy, Mexico, Netherlands, Norway, Poland, Portugal, Romania, Russian Federation, Saudi Arabia, Spain, Switzerland, Turkey, Austria, Ireland and more
F2G Biotech GmbH
Iqvia Pty Ltd

Recruiting

Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options (FORMULA-OLS)

Invasive Fungal Infections

United States, Netherlands, Israel, Spain, Korea, Republic of, Belgium, Australia, Germany, France, Brazil, Poland, Egypt, Russian Federation, Thailand, Turkey, United Kingdom, Vietnam
Gilead Sciences

Completed

Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

HCV Infection

United States, France, Australia, Puerto Rico, Spain
GlaxoSmithKline

Completed

A Study to Assess Frailty of Subjects During ZOSTER-006 and ZOSTER-022

Herpes Zoster

United States, Australia, Germany, Spain, Japan, Taiwan, Sweden, Korea, Republic of, Hong Kong, Mexico, Canada, France, Italy, Brazil, Estonia, United Kingdom, Czechia, Finland
University of Calgary
Medical University of South Carolina; University of Colorado, Denver; The Hospital... and other collaborators

Recruiting

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection (HIKO-STEC)

Hemolytic-Uremic Syndrome | Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

United States, Canada
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
AbbVie

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1

HIV Infection | HIV-1 | Human Immunodeficiency Virus (HIV)

United States, Australia, Canada, Puerto Rico
ViiV Healthcare
GlaxoSmithKline

Completed

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir (DTG) Plus Lamivudine (3TC) With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Participants (Gemini 2)

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Argentina, Spain, Germany, Belgium, Australia, Canada, United Kingdom, Italy, Romania, Taiwan, Russian Federation, Mexico, France, Switzerland, Peru, Poland, Portugal

Clinical Trials on Coinfection in South Africa

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