Clinical Trials on Cold Agglutinin Disease (CAD)

Total 6718 results

Sanofi

Recruiting

Cold Agglutinin Disease Real World Evidence Registry (CADENCE)

Cold Agglutinin Disease (CAD) | Cold Agglutinin Syndrome (CAS)

United States, Austria, France, Italy, Germany, Japan, Spain, United Kingdom
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Short Course of Bortezomib in Anemic Patients With Refractory Cold Agglutinin Disease (CAD0111)

Refractory Cold Agglutinin Disease

Italy
Novartis Pharmaceuticals

Active, not recruiting

Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders

Immune Thrombocytopenia (ITP) | Cold Agglutinin Disease (CAD)

United States, Spain, Germany, Korea, Republic of, United Kingdom, Italy
Bioverativ, a Sanofi company

Completed

A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Who Have a Recent History of Blood Transfusion (Cardinal Study)

Agglutinin Disease, Cold

United States, Israel, Australia, Spain, Austria, Germany, Belgium, France, Canada, Italy, Japan, Norway, Netherlands, United Kingdom
Bioverativ, a Sanofi company
Assign Data Management and Biostatistics GmbH; Quest Diagnostics-Nichols Insitute and other collaborators

Completed

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders (BIVV009-01)

End-stage Renal Disease (ESRD) | Cold Agglutinin Disease (CAD) | Bullous Pemphigoid (BP) | Warm Autoimmune Hemolytic Anemia (WAIHA)

Austria
CardioDx

Completed

Investigation of a Novel Gene Expression Test (ASGES or Corus CAD) for Diagnosis of Obstructive Coronary Artery Disease (REGISTRY-I)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx
Cardiovascular Research Foundation, New York; Piedmont Heart Institute, Inc...

Completed

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES) (COMPASS)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree (PREDICT)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern (IMPACT-CARD)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Understanding the Effect of Metformin on Corus CAD (or ASGES) (MET)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD
CardioDx

Withdrawn

Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making (CU-PCP)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Clinical Utility of an Age, Sex, and Gene Expression Score (ASGES or Corus CAD) in African American Patients. (AACU)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx
Mayo Clinic

Completed

Effect of Exercise Stress Testing on Peripheral Gene Expression Using Corus CAD (or ASGES) Diagnostic Test (EXERCISE)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings (PRESET)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making (UCU-CARD)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis (IMPACT-PCP)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
Cairo University

Unknown

Comparing Nano Hybrid Composite Blocks With Ceramic Blocks in Indirect Restorations 2. Protocol Registration:

the Clinical Performance of Indirect Restoration Fabricated From Nanohybrid Cad Cam Composite Blocks and Ceramic Blocks

Egypt
Swedish Orphan Biovitrum

Suspended

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With Cold Agglutinin Disease (CAD)

Cold Agglutinin Disease

Spain, Belgium, Norway, United States, Japan, United Kingdom, Netherlands, Canada, Hungary, Austria, Finland, Georgia, Germany, Italy
Sanofi

Completed

Sutimlimab (BIVV009) for the Adult Participants With Cold Agglutinin Disease (CAD) Who Have Completed Phase 3 Studies (CARDINAL or CADENZA) in Japan

Cold Agglutinin Disease

Japan
Bioverativ, a Sanofi company

Completed

A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Without A Recent History of Blood Transfusion (Cadenza)

Cold Agglutinin Disease

United States, United Kingdom, Israel, Australia, Spain, Austria, Germany, France, Belgium, Japan, Canada, Netherlands, Italy, Norway
University Hospital, Essen
Alexion Pharmaceuticals

Completed

Therapy of Chronic Cold Agglutinin Disease With Eculizumab (DECADE)

Cold Agglutinin Disease

Germany
University of Bergen

Completed

Therapy for Chronic Cold Agglutinin Disease

Cold Agglutinin Disease

Norway, Russian Federation
Stichting Hemato-Oncologie voor Volwassenen Nederland

Not yet recruiting

Zanubrutinib in Primary Cold Agglutinin Disease (HOVON169CAD)

Lymphoma

Norway, Netherlands, Denmark, Belgium
National Taiwan University Hospital

Recruiting

lncRNAs as a Biomarker to Assess the Therapeutic Impact of Oral Absorbent ± Probiotics in CKD Patients With PAD

CKD | PAD

Taiwan
Gliknik Inc.

Recruiting

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

First in Man Study to Evaluate Initial Safety

United Kingdom
Bioverativ, a Sanofi company

Active, not recruiting

Safety and Tolerability Study in Adults With Cold Agglutinin Disease Previously Treated With SAR445088 or Never Treated With SAR445088

Autoimmune Haemolytic Anaemia

Netherlands, Germany, Italy, Norway, United Kingdom
Bioverativ, a Sanofi company

Completed

A Safety and Tolerability Study of BIVV020 in Adults With Cold Agglutinin Disease

Autoimmune Haemolytic Anaemia

United States, Germany, Italy, Netherlands, Norway, United Kingdom
Brigham and Women's Hospital

Completed

Study of Perfusion and Anatomy's Role in Coronary Artery (CAD) (SPARC)

Known CAD, or Intermediate-high Pretest Likelihood for CAD

United States, Canada
Boston Scientific Corporation

Terminated

Trial for A Novel Facilitated Antegrade Steering Technique in Revascularization of Coronary Chronic Total Occlusions

CAD

China
Helse Fonna

Completed

Bendamustine and Rituximab Combination Therapy for Cold Agglutinin Disease (CAD5)

Autoimmune Hemolytic Anemia | Cold Agglutinin Disease

Finland, Denmark, Norway
Janssen Scientific Affairs, LLC
HCA Research Institute, LLC

Recruiting

A Study to Assess the Engagement and Usefulness of Care4Today Digital Platform for Disease Management in Coronary Artery Disease (CAD) and/or Peripheral Artery Disease (PAD) Population (IPACE-CVD)

Coronary Artery Disease (CAD) | Peripheral Artery Disease (PAD)

United States
Maatschap Cardiologie Zwolle
Diagram B.V.

Completed

Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk

Coronary Artery Disease (CAD) | Peripheral Arterial Disease (PAD)

Netherlands
Apellis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With Warm Type Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)

Cold Agglutinin Disease | Warm Autoimmune Hemolytic Anemia

United States
Mayo Clinic

Completed

Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial (CARE)

Aging | CAD

United States
Meridian Bioscience, Inc.

Completed

Equivalence of New Breath AnalyzerCompared to Currently BreathID System in Assessment of Liver Function

Healthy Volunteers | Chronic Liver Disease (CLD)

Israel
Bayer

Active, not recruiting

Study to Learn More About the Safety and Effectiveness of Rivaroxaban (Xarelto) When Given Together With Acetylsalicylic Acid to Indian People With Narrowing of the Arteries of the Heart (CAD) and/or With Reduced Blood Flow in the Arteries of the Legs and Arms With Symptoms (Symptomatic PAD)

Coronary Artery Disease (CAD) | Prevention of Atherothrombotic Events | Symptomatic Peripheral Artery Disease (Symptomatic PAD)

India
Indiana University
American Heart Association

Completed

Beating the Blues for Your Heart (BtB-Heart)

Depression | Depressive Symptoms | Heart Disease | Coronary Artery Disease (CAD) | Cardiovascular Disease (CVD)

United States
Glostrup University Hospital, Copenhagen
Steno Diabetes Center Copenhagen

Completed

Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease

Type 2 Diabetes | CHD | CVD | AMI | COLD

Denmark
Azura Ophthalmics
The University of New South Wales

Completed

An Evaluation of AZR-MD-001 as Treatment for Meibomian Gland Dysfunction (MGD) or Contact Lens Discomfort (CLD)

Meibomian Gland Dysfunction (MGD) | Contact Lens Discomfort (CLD)

Australia
Parc de Salut Mar

Completed

Improvement of Transient Elastography Applicability and Diagnostic Accuracy to Identify Significant Fibrosis by Experienced Operators Using the M and XL Probe.

Chronic Liver Diseases (CLD)

Spain
National Taiwan University Hospital

Recruiting

Oral Absorbent and Probiotics in CKD Patients With PAD on Gut Microbiota, IncRNA, Metabolome, and Vascular Function

CKD | PAD - Peripheral Arterial Disease

Taiwan
National Taiwan University Hospital

Recruiting

The Application of a Portable Multichannel ECG System for the Patients Suspected to Have Possible CAD or ACS

CAD

Taiwan
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Hypertension and Injury

Arterial Hypertension | CAD

Germany
Indiana University
National Institute of Mental Health (NIMH)

Completed

Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED) (INFLAMED)

Depression | Depressive Symptoms | Heart Disease | Major Depressive Disorder | Coronary Artery Disease (CAD) | Cardiovascular Disease (CVD)

United States
Peking University Third Hospital
First Hospital of China Medical University

Completed

Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

COPD Exacerbation | CAP
National Heart Centre Singapore

Unknown

Targeting Mitochondrial Fusion and Fission to Prevent Atherosclerosis: Getting the Balance Right (MITOFFA)

CAD Patients

Singapore
AstraZeneca

Completed

Prevalence of Peripheral Arterial Disease in Subject With a Moderate Risk of Cardiovascular (CV) Disease (CVD) in Primary Prevention (PANDORA)

Peripheral Arterial Disease (PAD) | Moderate Risk for Cardiovascular Disease (CVD)

France, Netherlands, Switzerland, Greece, Belgium, Italy
Medical University of Graz
Medical University of Vienna

Unknown

Graz Osteoprotegerin as a Risk Factor (GORF) Study

Prevalent OPG and RANKL Excession in Patients With CAD

Austria
University of Alberta
Canadian VIGOUR Centre

Completed

Remote Ischemic Conditioning in STEMI to Decrease Infarct Size (RemCon-STEMI)

STEMI | CAD
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD (CLEAR-CAD)

Chest Pain | CAD

Netherlands

Clinical Trials on Cold Agglutinin Disease (CAD)

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