Clinical Trials on Colon Carcinoma in United Kingdom

Total 11422 results

University College, London

Not yet recruiting

Early diAgnosis Real-Time Healthcare System for CANcer Trial (EARTHSCAN)

Polyps | Colon Polyp | Adenoma Colon | Colorectal Polyp | Polyps of Colon

United Kingdom
University Hospital Plymouth NHS Trust

Active, not recruiting

I-FIGS Feasibility Study (I-FIGS)

Hepatocellular Carcinoma | Liver Cancer | Liver Metastasis Colon Cancer

United Kingdom
London North West Healthcare NHS Trust

Completed

Water-only Versus Water-CO2 (Hybrid) Colonoscopy Insertion Technique (WAVE)

Colon Polyp

United Kingdom
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Completed

Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen (WISE)

Sigmoid, Sigmoid Colon, Neoplasm, Cancer

United Kingdom
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

Recurrent Colon Carcinoma | Metastatic Colorectal Carcinoma | Stage IV Colon Cancer AJCC v7 | Stage IVA Colon Cancer AJCC v7 | Stage IVB Colon Cancer AJCC v7 | Refractory Colorectal Carcinoma

United States
University College, London

Active, not recruiting

CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy (CADDIE)

Polyps | Colon Polyp | Adenoma Colon | Colorectal Polyp

United Kingdom
Toray Industries, Inc

Completed

A Study of TRK-950 in Patients With Advanced Solid Tumors

Cholangiocarcinoma | Colon Cancer | Locally Advanced or Metastatic Solid Carcinomas

France, United States
National Cancer Institute (NCI)

Active, not recruiting

Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial)

Colon Carcinoma | Rectal Carcinoma

United States
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany; University of Oxford; University of Surrey

Terminated

Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer (POLEM)

Microsatellite Instability | Stage III Colon Cancer | POLE Exonuclease Mutant Colon Cancer

United Kingdom
London North West Healthcare NHS Trust

Completed

Detection in Tandem Endocuff Cap Trial (DETECT)

Colonic Neoplasms | Colo-rectal Cancer | Colon Adenoma | Adenomas Serrated

United Kingdom
National Cancer Institute (NCI)

Completed

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal... and other conditions

United States
University College, London
University College London Hospitals; Merck Sharp & Dohme LLC; University of Leeds and other collaborators

Recruiting

NEOadjuvant PembRolizumab In Stratified Medicine - ColoRectal Cancer (NEOPRISM-CRC)

Adenocarcinoma of the Colon

United Kingdom
Roswell Park Cancer Institute
National Cancer Institute (NCI); Boehringer Ingelheim; National Comprehensive...

Completed

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Stanford University

Completed

Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm

Polyp of Colon | Colo-rectal Cancer | Adenomatous Polyp of Colon

United States
University of Washington
National Cancer Institute (NCI)

Terminated

A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer (ADAPT)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Rectal Mucinous Adenocarcinoma | Rectal Signet Ring Cell Adenocarcinoma

United States
Howard S. Hochster, MD

Recruiting

Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery

Stage IV Colon Cancer AJCC v8 | Stage IVA Colon Cancer AJCC v8 | Stage IVB Colon Cancer AJCC v8 | Stage IVC Colon Cancer AJCC v8 | Metastatic Colon Carcinoma

United States
London North West Healthcare NHS Trust

Completed

Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection? (INWARD)

Adenoma Colon | Serrated Adenoma

United Kingdom
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; Syntrix Biosystems, Inc.

Recruiting

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Stage III Colon Cancer AJCC v8 | Colon Adenocarcinoma | Microsatellite Stable Colon Carcinoma | Stage IIB Colon Cancer AJCC v8 | Stage IIC Colon Cancer AJCC v8

United States
Ethicon Endo-Surgery

Completed

A Prospective, Multi-Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left-Sided Colorectal Anastomoses (EPMCS-CA)

Left-sided Colon Resection

United States, United Kingdom, Belgium, Germany, Spain
Lancashire Teaching Hospitals NHS Foundation Trust
Lancaster University

Recruiting

Enteral Feeding of Fibre to Improve Microbiota

Colon Disease | Bowel Dysfunction | Ileum--Diseases

United Kingdom
Northumbria University
Newcastle University; York St John University

Unknown

Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth (AEROBIC)

Colon Cancer | Colon Adenocarcinoma

United Kingdom
University of Nottingham

Completed

The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery (POETold)

Quality of Life | Delirium | Prostatic Neoplasms | Surgery | Colorectal Carcinoma | Bladder Carcinoma | Colon Carcinoma | Impaired Cognition | Abdominal Hysterectomy (& Wertheim) | Renal Carcinoma

United Kingdom
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
Burzynski Research Institute

Withdrawn

Antineoplaston Therapy in Treating Patients With Colon Cancer

Stage IV Colon Cancer | Recurrent Colon Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

Edrecolomab in Treating Patients With Stage II Colon Cancer

Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIA Colon Cancer | Stage IIB Colon Cancer | Stage IIC Colon Cancer

United States
NEC Corporation
Meditrial Europe Ltd.; Meditrial USA Inc.

Recruiting

Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy (COLOWISE)

Colorectal Cancer | Polyp of Colon | Adenoma Colon

United States, Italy, Germany, United Kingdom
GlaxoSmithKline

Completed

Effects Of GW876008 On The Bowel In Patients With Irritable Bowel Syndrome

Irritable Colon

United Kingdom
GlaxoSmithKline

Completed

Study to Assess the Effect Of Alosetron On Mucosal Blood Flow

Irritable Colon

United Kingdom
Stanford University

Completed

Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy

Polyp of Colon | Colo-rectal Cancer | Adenomatous Polyp of Colon

United States
London North West Healthcare NHS Trust

Active, not recruiting

Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) (BiCyCLE-NMES)

Colorectal Cancer | Rectal Cancer | Sarcopenia | Advanced Cancer | Colon Cancer | Colo-rectal Cancer | Sarcopenic Obesity | Recurrent Rectal Cancer

United Kingdom
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Edward Kim
National Cancer Institute (NCI)

Completed

Oxaliplatin Microdosing Assay in Predicting Exposure and Sensitivity to Oxaliplatin-Based Chemotherapy

Colon Adenocarcinoma

United States
Imperial College London

Completed

Optical Polyp Testing for In Vivo Classification (OPTIC)

Colonic Diseases | Colonic Polyp | Colonic Neoplasms | Colonic Cancer | Colonic Adenocarcinoma | Colonic Adenoma | Colonic Carcinoma | Colonic Dysplasia | Colon Hyperplastic Polyp

United Kingdom
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Janssen Scientific Affairs, LLC

Completed

Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal Cancers

Colorectal Cancer | Colon Cancer | Colorectal Carcinoma | Colon Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
University of Nottingham
Quadram Institute Bioscience

Recruiting

Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI (RUFUS)

Colon, Irritable

United Kingdom
GlaxoSmithKline

Terminated

Sb-705498 Rectal Pain Study

Irritable Colon

United Kingdom
University of California, San Francisco
Bristol-Myers Squibb; Pfizer

Terminated

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal... and other conditions

United States
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | ERBB2 Gene Amplification | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon Cancer AJCC v7 | Stage... and other conditions

United States, Puerto Rico
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Advanced Colon Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer... and other conditions

United States
Norgine

Completed

Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus a Sodium Picosulfate and Magnesium Salt Solution Using Day Before-Only Dosing Regimen in Adults.

Colorectal Cancer | Colorectal Carcinoma | Colon Cleansing

Netherlands, United Kingdom, Spain, Germany, Italy, Poland
University Hospitals Cleveland Medical Center
Apollo Endosurgery, Inc.

Completed

Apollo Overstitch, a Treat and Resect Model (Overstitch)

Colon Malignant Tumor | Colon Benign Tumor

United States
Norgine

Completed

Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus Trisulfate Solution Using 2-Day Split-Dosing Regimen in Adults (NOCT)

Colon Cancer | Colorectal Carcinoma | Colon Cleansing

United States
UNC Lineberger Comprehensive Cancer Center

Withdrawn

Crossover Evaluation of Effect of Atorvastatin on PK of Irinotecan in CRC Patients Receiving FOLFIRI

Advanced Adenocarcinoma of the Colon or Rectum

United States
National Cancer Institute (NCI)

Completed

Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery

Adenocarcinoma of the Rectum | Stage I Colon Cancer | Stage I Rectal Cancer | Stage II Colon Cancer | Stage II Rectal Cancer | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
Perspectum

Active, not recruiting

Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing (Precision1)

Liver Cancer | Liver Metastasis Colon Cancer

United Kingdom

Clinical Trials on Colon Carcinoma in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uruguay

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