Clinical Trials on Colorectal Neoplasm in United Kingdom

Total 49558 results

Novartis Pharmaceuticals

Completed

LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE) (SIGNATURE)

Tumors With CDK4/6 Pathway Activation

United States
Prana Biotechnology Limited

Completed

Effect of PBT2 in Patients With Early to Mid Stage Huntington Disease (Reach2HD)

Huntington Disease

United States, Australia
Pfizer

Terminated

Open Label Sumanirole Study of Safety, Tolerability, and Therapeutic Response In Patients With Parkinson's Disease

Parkinson Disease

Colombia, United States, Argentina, Puerto Rico
Elan Pharmaceuticals

Completed

Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.

Stroke | Multiple Sclerosis | Muscle Spasticity | Spinal Cord Injury

United States
Newron Pharmaceuticals SPA

Completed

MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist (MOTION)

Idiopathic Parkinson's Disease

United States, Spain, Brazil, Peru, Colombia, Germany, Argentina, India, Croatia, Czech Republic, Italy, South Africa, Finland, Portugal, Canada, Slovakia, Bulgaria, Chile, Mexico, Poland
AbbVie

Completed

Study Comparing Continuous Subcutaneous Infusion Of ABBV-951 With Oral Carbidopa/Levodopa Tablets For Treatment Of Motor Fluctuations In Adult Participants With Advanced Parkinson's Disease

Parkinson's Disease (PD)

United States, Australia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States, Italy
National Cancer Institute (NCI)

Suspended

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Down Syndrome | Recurrent B Acute Lymphoblastic Leukemia

United States, Canada, Puerto Rico, Australia
Pfizer

Completed

Study Evaluating Sumanirole for the Treatment of the Signs and Symptoms of Early Parkinson's Disease

Parkinson Disease

United States, Australia, Spain, Italy, Belgium, Germany, Austria, Peru, Greece, France, Argentina, Puerto Rico, Colombia, Mexico
Adamas Pharmaceuticals, Inc.

Completed

ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study) (EASE LID)

Parkinson's Disease | Dyskinesia | Levodopa Induced Dyskinesia (LID)

United States, Canada
Jazz Pharmaceuticals

Completed

A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

Parkinson Disease | Excessive Sleepiness

United States
GlaxoSmithKline

Completed

Investigational Parkinson's Disease In Patients Not Well Controlled On L-dopa

Parkinson Disease

United States, France, Spain, Poland, Belgium, Hungary, Germany, Italy, Czech Republic
Enterin Inc.

Completed

Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET) (KARMET)

Parkinson Disease | Constipation

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder (TD)

Tourette's Disorder

Germany, United States, Bulgaria, Romania, Ukraine
Sun Pharma Advanced Research Company Limited

Active, not recruiting

PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

Early Parkinson Disease

United States, Spain, India, Hungary, Slovakia, Poland
Duke University

Active, not recruiting

Reducing Disparities in the Quality of Advance Care Planning for Older Adults (EQUALACP)

End Stage Liver Disease | Diabetes Complications | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Amyotrophic Lateral Sclerosis | End Stage Renal Disease | Metastatic Cancer | Interstitial Lung Disease | Congestive Heart Failure

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

Juvenile Myelomonocytic Leukemia | Childhood Acute Myeloid Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Childhood Chronic Myelogenous Leukemia | Childhood Myelodysplastic Syndromes | Chronic Phase Chronic Myelogenous Leukemia | Previously Treated Myelodysplastic... and other conditions

United States
Children's Hospital of Philadelphia
Illumina, Inc.

Active, not recruiting

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Mucopolysaccharidoses | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2 Gangliosidosis | Zellweger... and other conditions

United States
Medtronic Cardiac Rhythm and Heart Failure

Completed

Improve Sudden Cardiac Arrest Study

Ventricular Arrythmia | Sudden Cardiac Arrest

China, Korea, Republic of, Taiwan, Argentina, Colombia, Singapore, Russian Federation, India, South Africa, Malaysia, United Arab Emirates, Belarus, Brazil, Egypt, Mexico, Tunisia
Azevan Pharmaceuticals
National Institute of Neurological Disorders and Stroke (NINDS); NeuroNEXT...

Completed

Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease

Huntington's Disease | Irritable Mood

United States
Adamas Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID. (ALLAY-LID-I)

Parkinson's Disease | Levodopa Induced Dyskinesias (LID)

France, Spain, Germany, Canada, United States
Avita Medical

Completed

RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

Cellulitis | Surgical Wound | Skin Cancer | Infection | Crush Injuries | Degloving Injuries | Gun Shot Wound | Necrotizing Fasciitis | Laceration of Skin | Full-thickness Skin Defects

United States
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Recruiting

North American Prodromal Synucleinopathy Consortium Stage 2 (NAPS2)

Parkinson Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias | Lewy Body Dementia

United States, Canada
BioSante Pharmaceuticals

Completed

Safety and Efficacy of LibiGel® for Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women (BLOOM)

Hypoactive Sexual Desire Disorder

United States, Canada
The Radiosurgery Society
VisionTree

Recruiting

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Neoplasms | Trigeminal Neuralgia | Arteriovenous Malformation of Central Nervous System

United States, Australia
National Institute on Aging (NIA)

Completed

Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)

Parkinson Disease | Dementia

United States
Novartis Pharmaceuticals

Completed

Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Parkinson Disease | Dyskinesia, Drug-Induced | Levodopa

Italy, United States, Australia, France, Germany, Canada
Longboard Pharmaceuticals

Completed

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)

Dravet Syndrome | Lennox Gastaut Syndrome | Developmental and Epileptic Encephalopathy

United States, Australia
Biotie Therapies Inc.

Terminated

Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients (TOZ-PD)

Idiopathic Parkinson's Disease

Germany, Spain, Canada, United States, Italy, Austria, Czechia
Theranexus

Completed

Safety and Efficacy of THN102 in Patients With Parkinson's Disease and Excessive Daytime Sleepiness

Parkinson Disease

United States, France, Czechia, Germany, Hungary
Boehringer Ingelheim

Completed

Efficacy, Safety, Tolerability of Pramipexol ER Versus Pramipexol IR Versus Placebo in Early PD Patients

Early Parkinson Disease (Early PD)

United States, Argentina, Austria, Czech Republic, Finland, Germany, Hungary, India, Japan, Malaysia, Russian Federation, Slovakia, Taiwan, Ukraine
GlaxoSmithKline

Completed

Onset Motor Complications Using REQUIP CR (Ropinirole Controlled-release) As Add-on Therapy To L-dopa In Parkinson's

Parkinson's Disease | Parkinson Disease | Dyskinesias

United States
Adamas Pharmaceuticals, Inc.

Completed

Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia (EASE LID 3)

Parkinson's Disease (PD) | Dyskinesia | Levodopa-Induced Dyskinesia (LID)

France, Spain, United States, Germany, Austria
Adamas Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Amantadine Hydrogen Chloride (HCl) ER Tablets in Parkinson's Disease Subjects With LID (ALLAY-LID-II)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

France, Germany, Canada, United States, Spain
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia | Adult T Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Adult L1 Acute Lymphoblastic Leukemia | Adult L2 Acute Lymphoblastic...

United States
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

Efficacy and Safety Study of Satralizumab (SA237) as Monotherapy to Treat Participants With Neuromyelitis Optica (NMO) and Neuromyelitis Optica Spectrum Disorder (NMOSD)

Neuromyelitis Optica (NMO) | NMO Spectrum Disorder (NMOSD)

United States, Korea, Republic of, Malaysia, Turkey, Bulgaria, Canada, Poland, Puerto Rico, Romania, Croatia, Georgia, Italy, Philippines, Taiwan, Ukraine
National Cancer Institute (NCI)

Completed

Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
National Cancer Institute (NCI)

Completed

Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States, Israel
National Cancer Institute (NCI)

Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Down Syndrome | B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States, Canada, Puerto Rico, Australia, New Zealand
Kodiak Sciences Inc

Completed

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO) (BEACON)

Macular Edema | Retinal Vein Occlusion

Spain, United States, Latvia, Israel, France, Italy, Hungary, Germany, Poland, Slovakia, Puerto Rico, Czechia
Boston Scientific Corporation

Completed

S-ICD® System Post Approval Study

Primary Prevention of Sudden Cardiac Arrest | Secondary Prevention of Sudden Cardiac Arrest

United States
Novartis

Completed

A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa

Parkinson's Disease

United States, Canada, Czechia, Israel, Italy, Poland, Portugal, Turkey
Solvay Pharmaceuticals

Completed

SLV308 for Treatment of Patients With Early Parkinson's Disease

Early Stage Parkinson's Disease

United States, Argentina, Belgium, Bulgaria, Canada, Chile, Colombia, Croatia, Finland, India, Israel, Mexico, New Zealand, Peru, Romania, Russian Federation, Serbia, Slovakia, South Africa, Sweden, Ukraine
Neurocrine Biosciences

Completed

Safety and Efficacy Study of NBI-98854 in Adults With Tourette Syndrome

Tourette Syndrome

United States
Beth Israel Deaconess Medical Center
Schering-Plough

Completed

Study of Long-term Peg Intron vs. Colchicine in Non-responders. (COPILOT)

Cirrhosis | Hepatitis C Virus | Advanced Fibrosis

United States
Solvay Pharmaceuticals

Completed

An Open Label SLV308 Safety Extension to Study S308.3.001 in Early PD Patients

Early Stage Parkinson's Disease

United States, Argentina, Belgium, Bulgaria, Canada, Chile, Colombia, Croatia, Finland, India, Israel, Mexico, New Zealand, Peru, Romania, Russian Federation, Serbia, Slovakia, South Africa, Sweden, Ukraine
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Enrolling by invitation

North American Prodromal Synucleinopathy Consortium (NAPS)

Parkinson Disease | Lewy Body Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Secondary Acute Myeloid Leukemia | Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic... and other conditions

United States, Canada, Australia, Puerto Rico
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's Disease (HART)

Huntington Disease

United States, Canada

Clinical Trials on Colorectal Neoplasm in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mongolia

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Rare Diseases

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