Clinical Trials on Complement 3 Glomerulopathy

Total 754 results

University of South Florida
Pfizer; National Ataxia Foundation; Bob Allison Ataxia Research Center (BAARC)

Completed

Study to Determine the Safety and Tolerability of Varenicline (Chantix®) in Treating Spinocerebellar Ataxia Type 3

Spinocerebellar Ataxia Type 3

United States
Northwestern University
National Cancer Institute (NCI); BrainUp Inc

Not yet recruiting

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma | Recurrent WHO Grade 4 Glioma

United States
Chulalongkorn University

Not yet recruiting

Venous Excess and Lung Ultrasound During Continuous Kidney Replacement Therapy in Critically Ill Patients (VExLUS-KRT)

Acute Kidney Failure Stage 3

Thailand
Bleeding and Clotting Disorders Institute Peoria...
Genentech, Inc.

Recruiting

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A (BCDI-XII)

Von Willebrand Disease, Type 3 | Concomitant VWD and Hemophilia

United States
Centre Hospitalier Universitaire de Nīmes

Recruiting

Study of Gut Microbiota Diversity in Children Aged 1-3 Years on Prolonged Antibiotic Prophylaxis for Grade 3 or Higher Vesicoureteral Reflux Compared With 2 Age-matched Control Groups (PROPHYBIOTA)

Vesicoureteral Reflux 3

France
Miriam Elfström
Karolinska University Hospital

Recruiting

Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden

Cervical Cancer | HPV Infection | CIN 2/3

Sweden
Hospital de Clinicas de Porto Alegre

Unknown

Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD (BIGPRO)

Spinocerebellar Ataxia Type 3 | Machado-Joseph Disease

Brazil
National University of Malaysia

Completed

Clinical Effects of Oral Trehalose In Patients With Spinocerebellar Ataxia 3

Spinocerebellar Ataxia 3

Malaysia
Ruijin Hospital

Unknown

R-CEOP-90/R-CEOP-70 Versus R-CHOP-50 in the Treatment of Diffuse Large B-cell Lymphoma and Follicular Lymphoma Grade 3B

Diffuse Large B-cell Lymphoma | Follicular Lymphoma Grade 3B

China
CENTOGENE GmbH Rostock

Completed

Epidemiological Analysis for Hereditary Angioedema Disease (EHA)

Abdominal Pain | Functional Abdominal Pain

United Kingdom, Germany, Turkey, Poland, Italy, Japan
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
University Hospital, Montpellier

Terminated

The Role of the Coagulation Pathways in Recurrent Angioedema (Angiocoag)

Chronic Spotaneous Urticaria, Idiopathic Non Histaminergic Angioderma, Hereditary Angioedema With C1 Inhibitor Deficiency

France
Ari Zimran
Pfizer

Active, not recruiting

A Multicenter, Safety and Efficacy Study of Taliglucerase Alfa in Subjects With Type 3 Gaucher Disease

Gaucher Disease, Type 3

Israel, Turkey, India
The Methodist Hospital Research Institute
Johns Hopkins University; University of Colorado, Denver; University of Pennsylvania and other collaborators

Active, not recruiting

Clinical Trial Readiness for SCA1 and SCA3 (READISCA)

Spinocerebellar Ataxia 3 | Spinocerebellar Ataxia Type 1

United States
Lexicon Pharmaceuticals
Sanofi

Completed

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control (SOTA-CKD3)

Type 2 Diabetes Mellitus | Chronic Kidney Disease Stage 3

United States, Argentina, Brazil, Canada, Colombia, Germany, Hungary, Israel, Italy, Mexico, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine
Hospital de Clinicas de Porto Alegre

Unknown

Astrocytic Markers and the Pre-ataxic Period of SCA3/MJD - BIGPRO Study Astrocytes

Spinocerebellar Ataxia Type 3 | Machado-Joseph Disease | SCA3 | MJD

Brazil
Sheffield Teaching Hospitals NHS Foundation Trust

Terminated

Creon Use in Coeliac Patients With Low Faecal Pancreatic Elastase

Patients With Coeliac Disease and Chronic Diarrhoea (>3 Loose/ Liquid Motions a Day for More Than 4 Weeks) | Patients With Pancreatic Exocrine Insufficiency

United Kingdom
Chinese PLA General Hospital

Completed

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
The Second Affiliated Hospital of Henan University...
Xuzhou Medical University; Xinqiao Hospital of Chongqing

Unknown

Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma (MatchCART)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 (CART19)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
University of Rochester
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Recruiting

Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease

Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Multi-cohort Study of Surufatinib Plus Sintilimab in Metastatic NEN and Pancreatic Carcinoma Who Failed Standard Chemotherapy

Pancreatic Carcinoma | Neuroendocrine Carcinoma | Neuroendocrine Tumor Grade 3

China
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Glioblastoma | WHO Grade 3 Glioma | Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Glioma | Recurrent Cholangiocarcinoma | WHO Grade 2 Glioma

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Terminated

Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)

Follicular Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma

United States
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Oxidative Capacity and Exercise Tolerance in Ambulatory SMA

Spinal Muscular Atrophy Type 3 | Mitochondrial Myopathy

United States
Shire

Completed

Efficacy and Safety Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease

Gaucher Disease, Type 3

Egypt, India, Tunisia
Astellas Pharma Global Development, Inc.

Approved for marketing

Expanded Access Study of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | FMS-like Tyrosine Kinase-3 (FLT3) Mutations

United States, Canada, Japan
Universidad de Antioquia
Barts and the London School of Medicine and Dentistry; Instituto Colombiano... and other collaborators

Completed

Optimal Strategy for the Management of ASCUS Cytology in Health Care Services of Medellin, Colombia (ASCUS-COL)

Cervical Cancer | Cervical Abnormalities | Cervical Intraepithelial Neoplasia Grade 2/3

Colombia
Hospital de Clinicas de Porto Alegre

Completed

Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3

Spinocerebellar Ataxia Type 3 | Machado Joseph Disease

Brazil
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | Prolymphocytic Leukemia and other conditions

China
University of Minnesota

Recruiting

MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

Gaucher Disease, Type 3

United States
National Cancer Institute (NCI)

Active, not recruiting

Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Refractory Follicular Lymphoma | Grade 3a Follicular Lymphoma

United States, Canada, Singapore
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy and Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma and other conditions

United States
University of Pennsylvania

Completed

CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

United States
Chinese PLA General Hospital

Unknown

Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
T. van der Poll
ZonMw: The Netherlands Organisation for Health Research and Development; Prothya...

Terminated

C1-inhibitor in Allergic ASThma Patients (CAST)

Asthma

Netherlands
Virginia Commonwealth University
University of Colorado, Denver; Washington University School of Medicine; University... and other collaborators

Recruiting

Trial Readiness and Endpoint Assessment in LGMD R1 (GRASP-01-003)

Limb Girdle Muscular Dystrophy | Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A | Limb Girdle Muscular Dystrophy Type R1 | LGMD2A

United States, Netherlands, United Kingdom
Changhua Christian Hospital

Recruiting

Chinese Medicine WT for Spinocerebellar Ataxia Type 3

Ataxia, Spinocerebellar | Insulin-Like Growth Factor I | Medicine, Chinese Traditional

Taiwan
Oslo University Hospital
The Research Council of Norway; St. Olavs Hospital

Active, not recruiting

Energy Balance and Breast Cancer Aspects-II (EBBA-II)

Stage I Breast Cancer | Stage II Breast Cancer | DCIS Grade 3 | LCIS, Lobular Carcinoma in Situ

Norway
Children's Hospital of Philadelphia
Patient-Centered Outcomes Research Institute; Johns Hopkins University; University... and other collaborators

Enrolling by invitation

Preserving Kidney Function in Children With Chronic Kidney Disease (PRESERVE)

Chronic Kidney Disease Stage 3 | Pediatric Kidney Disease | Chronic Kidney Disease Stage 2

United States
OPKO Health, Inc.

Completed

Repeated-dose Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of CTAP101, Immediate-release Calcifediol, High-dose Cholecalciferol, and Paricalcitol Plus Low-dose Cholecalciferol in Patients With Secondary Hyperparathyroidism, Chronic Kidney Disease 3-4 and Vitamin D Insufficiency

Vitamin D Insufficiency | CKD Stage 4 | CKD Stage 3 | Secondary Hyperparathyroidism Due to Renal Causes

United States
George Washington University
National Cancer Institute (NCI)

Recruiting

The Selfie Study- Assessing Novel Markers for Cervical Cancer Screening From Self-collected Samples (SELFIE)

Cervical Cancer | Human Papilloma Virus | CIN 2/3

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
University of California, San Francisco
National Institutes of Health (NIH); Fogarty International Center of the National...

Completed

Thermocoagulation for Treatment of Precancerous Cervical Lesions

HPV Infection | Human Immunodeficiency Virus | CIN 2/3

Kenya
University Hospital, Montpellier
Université Montpellier

Terminated

Transient Thermal Behavior and Diabetic Foot (PICOTE)

Diabetic Patients Type 1 and 2 | Podologic Grade From 0 to 3

France
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Lymphoproliferative Disorders

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma

United States
CANbridge (Suzhou) Bio-pharma Co., Ltd.

Recruiting

Phase 1/2 Study of CAN103 in Subjects With Gaucher Disease

Gaucher Disease, Type 1 | Gaucher Disease, Type 3

China
Hospices Civils de Lyon

Recruiting

Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients? (MS-CRRT)

Myocardial Stunning | Acute Kidney Injury KDIGO 3 | Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency

France
ProgenaBiome

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Parkinson's Disease

Parkinson Disease | Parkinsons Disease With Dementia | Parkinson-Dementia Syndrome | Parkinson Disease 2 | Parkinson Disease 3 | Parkinson Disease 4

United States
Maastricht University Medical Center
Netherlands Heart Foundation

Recruiting

Worm Study: Modifier Genes in Sudden Cardiac Death

Brugada Syndrome | Long QT Syndrome 3

Netherlands

Clinical Trials on Complement 3 Glomerulopathy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Togo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations