Clinical Trials on Congenital Anomalies in United Kingdom

Total 3876 results

University Hospital Birmingham NHS Foundation Trust
University of Birmingham; Dystrophic Epidermolysis Bullosa Research Association...

Enrolling by invitation

Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa

Junctional Epidermolysis Bullosa | Laryngo Onycho Cutaneous Syndrome

United Kingdom
Imperial College London

Completed

Diet and Hereditary Haemorrhagic Telangiectasia

Hereditary Haemorrhagic Telangiectasia (HHT)

United Kingdom
Liminal BioSciences Ltd.

Terminated

Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome

Alström Syndrome

United Kingdom
University College, London
University College London Hospitals

Unknown

Origins and Impact of EDS in Connective Tissues and Skin

Ehlers-Danlos Syndrome

United Kingdom
University College London Hospitals
Johns Hopkins University; Children's Hospital of Philadelphia; University of... and other collaborators

Completed

Survey of Current Management of Orthopaedic Complications in CMT Patients

Charcot-Marie-Tooth Disease

United Kingdom
King's College London

Completed

Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalities

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Solvay Dental 360

Completed

REFRAME RPD Post-Market Clinical Study

Missing Teeth | Dental Wear

United States, United Kingdom
National Cancer Institute (NCI)

Completed

Needs Assessment for Individuals and Families Affected by Dyskeratosis Congenita (DC) and Related Telomere Biology Disorders (TBD)

Dyskeratosis Congenita | Telomere Biology Disorders

United States
Novo Nordisk A/S

Completed

Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Birmingham Women's and Children's NHS Foundation...

Not yet recruiting

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula (iTOF)

Tracheo-Esophageal Fistula With Atresia of Esophagus

United Kingdom
Novo Nordisk A/S

Completed

Investigation of the Pharmacokinetics of NNC172-2021, at Two Different Dose Levels, in Healthy Japanese Subjects

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Novo Nordisk A/S

Completed

A Single Dose Trial Investigating Safety and Local Tolerability of Ascending Doses of Long Acting Activated Recombinant Human Factor VII in Healthy Male Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Emma Aitken
NHS Greater Glasgow and Clyde

Unknown

Local Anaesthesia vs Regional Block for Arteriovenous Fistulae

End Stage Renal Disease

United Kingdom
Medical College of Wisconsin

Terminated

Customized Orthosis for Children With Clubfoot

Congenital Talipes Equinovarus

United States
Haukeland University Hospital
Karolinska Institutet; University Hospitals Bristol and Weston NHS Foundation... and other collaborators

Completed

Dynamic Hormone Diagnostics in Endocrine Disease (ultradian)

Congenital Adrenal Hyperplasia | Acromegaly | Growth Hormone Deficiency | Cushing Syndrome | Primary Hyperaldosteronism | Adrenal Insufficiency

Norway, Sweden, Greece, United Kingdom
Marco Corridore

Completed

A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass

Congenital Heart Disease | Congenital Heart Defect

United States
Dynacure

Terminated

Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies (Unite-CNM)

Centronuclear Myopathy

France, Netherlands, United Kingdom, Belgium, Denmark, Germany
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia

Thalassemia

United States, Canada, United Kingdom
Oregon Health and Science University
University of Central Florida; Limbitless Solutions

Enrolling by invitation

Prosthetic Device in Children With Upper Congenital Limb Deficiency

Upper Limb Deformities, Congenital

United States
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
University Hospitals Bristol and Weston NHS Foundation...
University College, London; The Tuberous Sclerosis Association

Active, not recruiting

Acceptance and Commitment Therapy in Tuberous Sclerosis Complex (ACT in TSC)

Tuberous Sclerosis Complex

United Kingdom
Manchester University NHS Foundation Trust
University of Oxford; University of Liverpool

Completed

Timing of Stoma Closure in Neonates (ToSCiN)

Premature Birth | Enterocolitis, Necrotizing | Gastroschisis | Meconium Ileus | Bowel Obstruction | Atresia; Bowel | Perforation Bowel

United Kingdom
University College London Hospitals
Kingston University; Charcot Marie Tooth United Kingdom

Completed

BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease (BALTiC)

Charcot-Marie-Tooth Disease, Type IA

United Kingdom
Novo Nordisk A/S

Completed

Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
Centre Chirurgical Marie Lannelongue

Completed

Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves (Endopulm)

Congenital Heart Disease | Infective Endocarditis | Percutaneous Pulmonary Valve Implantation

France, Germany, Italy, Portugal, Saudi Arabia, Spain, United Kingdom
University of Southampton
Assistance Publique - Hôpitaux de Paris; Hacettepe University; Universitaire... and other collaborators

Unknown

PRospective Observational Multicentre Study on VAriability of Lung Function in Stable PCD Patients (PROVALF-PCD)

Primary Ciliary Dyskinesia

United Kingdom
Emory University

Withdrawn

Tranexamic Acid Effect on Platelet Aggregation Following Infant Cardiopulmonary Bypass

Heart Defect, Congenital

United States
Institut National de la Santé Et de la Recherche...

Unknown

Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB) (RDEB)

Recessive Dystrophic Epidermolysis Bullosa

France, United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

SMILES: Study of Montelukast in Sickle Cell Disease (SMILES)

Anemia, Sickle Cell | Sleep-Disordered Breathing

United Kingdom
Sokratis Stoumpos
NHS Greater Glasgow and Clyde

Completed

Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease (FeMRA in CKD)

Kidney Transplantation | Arteriovenous Fistula | Magnetic Resonance Angiography | Ferric Compounds | Vascular Grafting

United Kingdom
Sanofi
Bristol-Myers Squibb

Completed

Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation (CLARINET)

Heart Defects, Congenital

France, Canada, Brazil, Poland, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Sweden, India, Malaysia, Singapore, Taiwan, Belgium, Mexico, Argentina, Denmark, Egypt, Finland, Hungary, Israel, Norway, Korea, Republic of, Hong Kong and more
Maximilian Nussbaumer
Cambridge University Hospitals NHS Foundation Trust

Terminated

Mapping Sound Propagation Through the Human Lung for Better Diagnosis

Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Asthma | Lung Diseases, Interstitial | Bronchomalacia

United Kingdom
Medical College of Wisconsin
National Center for Research Resources (NCRR); Children's Hospital and Health...

Terminated

Erythropoietin and Pediatric Cardiac Surgery (EPO)

Congenital Heart Defect

United States
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Myotubular and Centronuclear Myopathy Patient Registry

X-linked Myotubular Myopathy | Centronuclear Myopathy | Myotubular Myopathy | Myotubular Myopathy 1 | Myotubular (Centronuclear) Myopathy | Centronuclear Myopathy, X-Linked

United Kingdom
Zimmer Biomet

Active, not recruiting

PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty

Avascular Necrosis | Inflammatory Arthritis | Osteoarthritis, Hip | Congenital Hip Dysplasia | Post-traumatic; Arthrosis | Rheumatoid Arthritis With Adequate Bone Quality

Netherlands, Finland, Belgium, France, Spain, Australia, Canada, United Kingdom
University of Rochester
National Center for Research Resources (NCRR); Rare Diseases Clinical Research... and other collaborators

Completed

Characteristics of Andersen-Tawil Syndrome

Andersen-Tawil Syndrome | Andersen Syndrome

United States, Canada, Italy, United Kingdom
Emory University

Completed

Adult Congenital Heart Disease Surgery

Congenital Disorders

United States
AEterna Zentaris

Completed

Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency

Growth Hormone Deficiency With Pituitary Anomalies

United Kingdom, United States, France, Poland, Spain, Austria, Germany, Italy, Serbia
Ohio State University
Nationwide Children's Hospital; American Heart Association

Completed

Neurodevelopment in Infants With Complex Congenital Heart Defects

Complex Congenital Heart Defect

United States
Children's Healthcare of Atlanta

Completed

Computer Modeling of Congenital Heart Disease

Congenital Disorders

United States
Children's Healthcare of Atlanta

Terminated

Pulse Oximetry Readings and Hourly Variation in Oximetry Readings With CHD

Congenital Disorders

United States
Children's Healthcare of Atlanta

Terminated

Percutaneous Interventions in Adults With CHD

Congenital Disorders

United States
Mayo Clinic

Completed

Genetic Variants in Nicotinamide Adenine Dinucleotide (NAD) Synthesis Pathway

Congenital Malformation | Vacterl Association

United States
Joanne Turner

Recruiting

Utility of the Cardiac Electrical BiomarkerDisease (VECTRA)

Acute Chest Syndrome

United Kingdom
Papworth Hospital NHS Foundation Trust

Recruiting

Portable Continuous Positive Airways Pressure (CPAP) in Excessive Central Airway Collapse (ECAC) Study

Respiratory Disease | Excessive Dynamic Airway Collapse | Tracheobronchomalacia | Excessive Central Airways Collapse

United Kingdom
NHS Greater Glasgow and Clyde

Unknown

Qutenza (Topical Capsaicin 8%) for Painful Arteriovenous Fistulae

Neuropathic Pain | Arteriovenous Fistulae

United Kingdom
Bangor University
Betsi Cadwaladr University Health Board

Completed

Handgrip Exercise for Arteriovenous Fistula Maturation

Chronic Kidney Disease

United Kingdom
Weill Medical College of Cornell University

Completed

Use of ROTEM® in Pediatric Cardiac Surgical Patients (PedsROTEM)

Congenital Heart Defect

United States
Russell Sage College
Albany Medical College

Enrolling by invitation

The Prevalence of the Linburg-Comstock Variation (LCV)

Anomaly; Hand

United States

Clinical Trials on Congenital Anomalies in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Brazil

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations