Clinical Trials on Degenerative Joint Disease in Spain

Total 17710 results

Zimmer, GmbH

Active, not recruiting

Zimmer POLAR Persona - TKA (EMEA Study)

Osteoarthritis | Rheumatoid Arthritis | Traumatic Arthritis | Polyarthritis | Severe Knee Pain | Severe Knee Disability

France, Spain, United Kingdom, Austria, Germany, Netherlands
Galapagos NV

Terminated

An Open-label, Long-term Extension Study With Filgotinib in Active Psoriatic Arthritis.

Psoriatic Arthritis

Estonia, Belgium, Bulgaria, Czechia, Poland, Spain, Ukraine
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effects of Multiple Rising Subcutaneous Doses of BI 655064 in Healthy Volunteers and in Rheumatoid Arthritis Patients With Prior Inadequate Response to Methotrexate Therapy

Healthy | Arthritis, Rheumatoid

Germany, Netherlands, New Zealand, Poland, Spain, Czechia
Bristol-Myers Squibb

Completed

Assessment of the Effectiveness of IV and SC Abatacept (Orencia) Patient Alert Cards in Patients With Rheumatoid Arthritis in a Sample of EU Countries

Rheumatoid Arthritis

United Kingdom, France, Spain, Germany, Sweden
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion (BALATON)

Macular Edema | Branch Retinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Tremeau Pharmceuticals, Inc.

Terminated

Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy (RESET-HA)

Hemophilic Arthropathy

United States, Italy, Turkey, Spain, Australia, Canada, Ukraine, Poland
Hoffmann-La Roche

Terminated

A Study of Combination Treatment With MabThera (Rituximab) and RoActemra (Tocilizumab) Versus RoActemra in Patients With Rheumatoid Arthritis With an Incomplete Response to Methotrexate

Rheumatoid Arthritis

France, Germany, Switzerland, United Kingdom, Spain, Netherlands, Greece, Poland
Ono Pharmaceutical Co. Ltd

Terminated

A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee (MOTION)

Pain | Osteoarthritis, Knee

Poland, Hungary, Spain, Denmark, United Kingdom
Hospital Universitari Vall d'Hebron Research Institute
UCB Pharma

Unknown

Serum Biomarkers Analysis in Patients With AR Treated With Anti-TMF (AROMA)

Rheumatoid Arthritis

Spain
Janssen Research & Development, LLC

Completed

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003

Pain | Osteoarthritis

United States, Poland, Spain, Canada, Belgium, Netherlands, Czechia, United Kingdom
Chromaderm, Inc.

Completed

Reduction in the Occurrence of Center-Involved Diabetic Macular Edema

Diabetic Retinopathy

United States, Canada, France, Denmark, Australia, Netherlands, Taiwan, Spain, Italy, Germany, Portugal, United Kingdom, Russian Federation, Poland, India, Brazil, Mexico
Galapagos NV

Completed

A Study to Assess Efficacy and Safety of Filgotinib in Ankylosing Spondylitis (TORTUGA)

Ankylosing Spondylitis

Belgium, Bulgaria, Czechia, Estonia, Poland, Spain, Ukraine
Sociedad Española De Medicina Interna
GlaxoSmithKline

Unknown

Compliance With Clinical Guidelines and Effect on Patient Outcome of Treatment of Hospitalised Exacerbations of COPD (ADEG-EPOC)

Pulmonary Disease, Chronic Obstructive

Spain
Pfizer

Completed

Dose-Escalating Multiple Dose Study of PD-0360324 in Combination With Methotrexate in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Czech Republic, Bulgaria, Poland, Slovakia, Spain, Mexico, Argentina
Pfizer

Completed

A Study To Evaluate The Effect Of CP-690,550 On Measures Of Kidney Function In Patients With Active Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Germany, Korea, Republic of, Spain, Czech Republic, Mexico, Poland, Russian Federation
UCB Biopharma SRL

Completed

A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU (C-VIEW)

Axial Spondyloarthritis (axSpA) | Anterior Uveitis (AU)

Czechia, Germany, Netherlands, Poland, Spain
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus (RETAIN)

Diabetic Macular Edema

Belgium, United Kingdom, Netherlands, Ireland, Switzerland, Italy, Hungary, France, Spain, Portugal, Poland, Czech Republic, Greece
TcLand Expression S.A.
Premier Research Group plc; Theradis pharma; Medpharmgene, Inc.

Terminated

Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy (PRINT)

Rheumatoid Arthritis

Canada, France, Hungary, Italy, Lithuania, Romania, Slovakia, Spain
Novartis

Completed

Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, Germany, Belgium, Italy, Netherlands, United States
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) (PROCLAIM)

Frontotemporal Dementia

United States, Australia, Belgium, Spain, United Kingdom, France
Janssen Research & Development, LLC

Completed

A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid Arthritis

Arthritis, Rheumatoid

United Kingdom, United States, Spain, Germany, Poland
Parc de Salut Mar
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation; Hospital...

Completed

Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal Intervention ((PENSA))

Alzheimer Disease | Cognitive Decline

Spain
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Biotest

Completed

Dose-finding of Multiple Dose of BT061 in Patients With Active Rheumatoid Arthritis Incompletely Controlled on Stable Methotrexate (MTX)

Rheumatoid Arthritis

Poland, Czech Republic, Germany, Hungary, Italy, Latvia, Spain
Hoffmann-La Roche

Completed

A Study Comparing Infusion Rates of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Pfizer

Completed

Extension Study Evaluating Etanercept in 3 Subtypes of Childhood Arthritis (CLIPPER2)

Juvenile Idiopahtic Arthritis

Belgium, France, Serbia, Spain, Germany, Slovakia, Colombia, Hungary, Czechia, Poland, Australia, Italy, Latvia, Lithuania, Mexico, Netherlands, Norway, Russian Federation, Slovenia
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

United States, Canada, Israel, United Kingdom, Denmark, France, Belgium, Italy, Netherlands, Switzerland, Spain
Novartis Pharmaceuticals

Completed

Double Blind, Placebo-controlled, Study of the Safety, Tolerability and Pharmacokinetics of AIN457 in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Netherlands, Germany, Belgium, Singapore, Spain, United States
University of Oxford
Amgen

Recruiting

AsseSSing Impact in pSoriatic Treatment (ASSIST)

Psoriatic Arthritis

Spain, France, United Kingdom, Germany, Italy
Corporacion Parc Tauli

Completed

Efficacy of HBVaxpro40© and Fendrix© in Patients With Chronic Liver Disease.

Liver Disease Chronic | Hepatitis B Virus

Spain
Janssen Research & Development, LLC

Completed

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002

Pain | Osteoarthritis

United States, Spain, Poland, United Kingdom
Dr. FRANCISCO J. BLANCO-GARCIA

Completed

A 24 Week Open Label Study of the Utility of Adalimumab in Active Axial Forms of Psoriatic Arthritis

Psoriatic Arthritis

Spain
Fundació Eurecat
Centre de Diagnosi per la Imatge; Instituto de Investigación Biomédica de Girona... and other collaborators

Not yet recruiting

Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity (FATHIS+)

Visceral Obesity | Non-alcoholic Fatty Liver | Postmenopausal

Spain
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

Belgium, Canada, United States, Israel, United Kingdom, Denmark, France, Italy, Netherlands, Switzerland, Spain
Swedish Orphan Biovitrum

Recruiting

Assessment of Macrophage Activation syndromE in STill's Disease (AMETHYST)

Still's Disease, Adult-Onset | Macrophage Activation Syndrome | Stills Disease, Juvenile-Onset

United States, Canada, France, Germany, Italy, Netherlands, Spain
Pfizer

Completed

Study of CE-224,535 A Twice Daily Pill To Control Rheumatoid Arthritis In Patients Who Have Not Totally Improved With Methotrexate

Arthritis, Rheumatoid

United States, Spain, Czechia, Korea, Republic of, Poland, Chile, Mexico
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Mabthera Alone and in Combination With Either Cyclophosphamide or Methotrexate in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Italy, Poland, Spain, Germany, United Kingdom, Canada, Israel, Australia, Netherlands, Czech Republic
Novartis Pharmaceuticals

Terminated

A Study to Evaluate the Safety, Tolerability and Efficacy of MHV370 in Participants With Sjogren's Syndrome (SjS) or Mixed Connective Tissue Disease (MCTD)

Sjogren Syndrome | Mixed Connective Tissue Disease

Spain, Hungary, Germany, China, Poland, Taiwan
Mundipharma Research GmbH & Co KG

Completed

OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects

Chronic Osteoarthritis

Spain, Belgium, Finland, Czechia, Germany, Hungary
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion (COMINO)

Central Retinal Vein Occlusion | Macular Edema | Hemiretinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Germany, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Pfizer
Eli Lilly and Company

Completed

Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder Replacement

Osteoarthritis

United States, Spain, Australia, Serbia, Germany, Canada, Japan, New Zealand, Hungary, Italy, Sweden, Lithuania, Portugal, Russian Federation, Slovakia
Zimmer Biomet

Recruiting

A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee

Osteoarthritis | Rheumatoid Arthritis | Complications; Arthroplasty | Traumatic Arthritis | Deformity of Limb | Post Traumatic Deformity

Italy, United States, Belgium, Denmark, France, Germany, Spain, United Kingdom
ACELYRIN Inc.

Completed

A Study to Investigate Efficacy, Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis

Psoriatic Arthritis

Poland, Hungary, Germany, Belgium, Czechia, Austria, Spain
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRYSTAL)

Central Retinal Vein Occlusion | Macular Edema

Greece, Hungary, Turkey, Australia, Austria, Netherlands, United Kingdom, Italy, Spain, Ireland, Portugal, Slovakia, Canada, Switzerland, Czech Republic, Poland, Denmark, Sweden
Abbott

Completed

Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis (DALI)

Rheumatoid Arthritis

Spain
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Spain, Hungary, Serbia, Bulgaria, Poland, Russian Federation, Latvia
University Hospital Virgen de las Nieves

Completed

Effects of Treatment of Chronic Stress in Patients With Lupus

Systemic Lupus Erythematosus

Spain
UCB Celltech
PRA Health Sciences

Terminated

UCB Proof of Concept Study in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

France, Italy, Spain, Sweden, United Kingdom
Amgen

Recruiting

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Behçet's Disease

Spain, Turkey, Israel, Greece
Groupe Hospitalier Pitie-Salpetriere

Completed

Remission and Flare in Psoriatic Arthritis: a Prospective 6-month Study With a Double Perspective. (ReFlaP)

Psoriatic Arthritis

United States, Austria, Brazil, Canada, Estonia, France, Germany, Italy, Romania, Russian Federation, Singapore, Spain, Turkey, United Kingdom

Clinical Trials on Degenerative Joint Disease in Spain

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