Clinical Trials on Developmental Defects of Enamel

Total 1675 results

University of Texas Southwestern Medical Center

Recruiting

Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex

Laparoscopic Cholecystectomy | Neuromuscular Blockade | Physiological Effects of Drugs | Urinary Retention Postoperative | Sugammadex | Neostigmine | Neuromuscular Blocking Agents

United States
Peking University People's Hospital
Peking University Shougang Hospital

Suspended

Apatinib Plus IE Chemotherapy (Ifosfamide and Etoposide) for Relapsed or Refractory Osteosarcoma (AIEO)

Effect of Drug | Toxicity, Drug

China
University Hospital, Caen

Unknown

VIGIP-SEP2: Evaluation of the Impact of the Training of Patients by a Nurse on the Adverse Drug Reaction Reporting by RRMS Patient Via a Mobile Application: Randomized Real-life Study (VIGIP-SEP2)

Multiple Sclerosis
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Michael C Willey

Not yet recruiting

Psychosocial Interventions for Young Adults With Hip Pain

Hip Pain Chronic | Hip Dysplasia | Hip Osteoarthritis | Hip Arthritis | Psychosocial Problem

United States
University of Aarhus

Completed

Health-related Quality of Life in Patients Undergoing Surgery for Pectus Carinatum (HRQoL)

Quality of Life | Pain, Postoperative | Somatosensory Disorders | Pectus Carinatum

Denmark
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Children's Memorial Health Institute, Poland

Completed

An Innovative Probiotic Product With Antiallergic Properties

Atopic Dermatitis | Food Allergy | Effects of Probiotics

Poland
Biogen

Completed

Pregnancy Exposure Registry for Avonex (Interferon Beta-1a)

Multiple Sclerosis | Pregnancy | Prenatal Exposure Delayed Effects

United States
Jules Bordet Institute

Unknown

Safety and Immunogenicity of Recombinant WT1 Antigen-Specific Cancer Immunotherapeutic Combined With Infusion of Treg Depleted T Cells for Adult WT1 Acute Myeloid Leukemia (ASCI)

Effects of Immunotherapy | Acute Myelogenous Leukemia | Myeloid Leukemia in Remission

Belgium
Beijing Tongren Hospital

Completed

Distinct Response of CD4+CD25+Foxp3+ and IL-10-secreting Type I T Regulatory Cells to Cluster Specific Immunotherapy in Allergic Rhinitis Children

Allergic Rhinitis | Effects of Immunotherapy

China
Biogen
AMS Advanced Medical Services GmbH

Completed

A Post-Authorization Safety Study of Interferon Beta Therapy in Participants With Multiple Sclerosis (PERFECT)

Multiple Sclerosis, Relapsing-Remitting

Germany
Bandim Health Project
University of Southern Denmark

Completed

Using BCG Vaccine to Protect Health Care Workers in the COVID-19 Pandemic

COVID-19 | Morbidity | Non-specific Effects of Vaccines | Absenteeism | Heterologous Immunity

Denmark
Crinetics Pharmaceuticals Inc.

Active, not recruiting

Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome

Carcinoid Tumor | Carcinoid Syndrome | Carcinoid | Carcinoid Tumor of Ileum | Carcinoid Tumor of Cecum | Carcinoid Syndrome Diarrhea | Carcinoid Intestine Tumor | Carcinoid Tumor of Liver | Carcinoid Tumor of Pancreas

United States, Brazil, Argentina, Canada, Mexico, Peru, Poland
Fundació Sant Joan de Déu

Completed

Safety Study of Dinutuximab Combined With Immunotherapy to Treat Neuroblastoma

Effects of Immunotherapy | Neuroblastoma | Neoplasm, Residual

Spain
Massachusetts General Hospital
Dana-Farber Cancer Institute; McKesson Foundation

Completed

Improving Outcomes in Cancer Patients on Oral Anti-Cancer Medications Using a Multi-modal Mobile Health Intervention (CORA)

Prostate Cancer | Renal Cell Cancer | Effects of Chemotherapy

United States
University Hospital, Strasbourg, France

Unknown

Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia (SPREAD)

Focal Epilepsy | Refractory Epilepsy | Focal Cortical Dysplasia

France
Hospices Civils de Lyon

Not yet recruiting

Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study (COGRare5)

Arteriovenous Malformations | Marfan Syndrome | Osler Rendu Disease | Vascular Anomaly | Lymphedema Primary | Cerebrospinal; Disorder

France
Thomas Jefferson University
Jawaharlal Nehru Medical College

Active, not recruiting

Neuroimaging Ancillary Study

Iron Deficiency Anemia | Child Development | Iron Deficiency Anemia of Pregnancy | Iron Deficiency Anemia Treatment | Neurodevelopmental Disorder of Foetus | Fetal Neurodevelopmental Disorder

India
University of North Carolina, Charlotte
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Herbal Therapy for Subcutaneous Injection Site Reactions in Multiple Sclerosis (MSSkin)

Multiple Sclerosis

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) (EXIST-2)

Lymphangioleiomyomatosis (LAM) | Tuberous Sclerosis Complex (TSC)

United States, United Kingdom, Germany, Italy, Russian Federation, Netherlands, Japan, Canada, Poland, France, Spain
Marmara University
National Institute of Allergy and Infectious Diseases (NIAID)

Unknown

Transcriptome and Metabolic Analyses of CHAPLE Disease (CHAPLEOMIC)

Protein-Losing Enteropathies | CD55 - Cluster of Differentiation Antigen 55 Deficiency | Primary Intestinal Lymphangiectasis | Complement Regulatory Factor Defect

Turkey
Murdoch Childrens Research Institute
National Health and Medical Research Council, Australia; Royal Children's Hospital and other collaborators

Recruiting

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents (GenV)

Communicable Diseases | Quality of Life | Inflammation | Obesity | Congenital Abnormalities | Genetics | Healthy Aging | Child Development | Diet | Mental Health | Disability | Injuries | Cognition | Child Health | Environmental Exposure | Noncommunicable Diseases | Physical Fitness | Intergenerational Relations | Social Determinants... and other conditions

Australia
Hirabai Cowasji Jehangir Medical Research Institute

Enrolling by invitation

YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition (Adol Cohort)

Anemia | Gestational Diabetes | Malnutrition, Child | Arrest of Bone Development or Growth | Constitutional Delay of Growth and Puberty | Muscle Tone Abnormalities

India
Grupo de Estudos Multicentricos em Onco-Hematologia

Completed

Superiority of VCD Versus CTD in Patients With Newly Diagnose Multiple Myeloma Eligible for Transplantation (GBRAM003r)

Multiple Myeloma | Effects of Chemotherapy
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia

Depression | Leukemia | Fatigue | Psychosocial Effects of Cancer and Its Treatment | Musculoskeletal Complications

United States
Avita Medical

Completed

RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

Cellulitis | Surgical Wound | Skin Cancer | Infection | Crush Injuries | Degloving Injuries | Gun Shot Wound | Necrotizing Fasciitis | Laceration of Skin | Full-thickness Skin Defects

United States
University of California, Los Angeles
Northwestern University

Recruiting

Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

Pain, Postoperative | Cerebral Palsy | Hip Dysplasia

United States
Boston University Charles River Campus
Massachusetts General Hospital; University of Michigan; National Institute on...

Recruiting

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

Aphasia, Primary Progressive | Stuttering, Developmental

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Quality of Life in Younger Leukemia and Lymphoma Survivors

Pain | Lymphoma | Leukemia | Fatigue | Small Intestine Cancer | Cancer Survivor | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment | Lymphoproliferative Disorder | Long-term Effects Secondary to Cancer Therapy in Adults

United States
The University of Texas at Dallas
University of Texas Southwestern Medical Center

Recruiting

Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation (MS-HDtDCS)

Multiple Sclerosis, Relapsing-Remitting

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Perioperative FOLFIRI VS Adjuvant FOLFIRI in Resectable Advanced CRC Failed to Oxaliplatin

Colorectal Neoplasms | Surgery | Metastasis | Effects of Chemotherapy | Local Neoplasm Recurrence

China
Cancer Hospital of Guangxi Medical University

Unknown

The Role of Adding Concurrent Chemotherapy to IMRT in the Treatment of Stage II Nasopharyngeal Carcinoma

Effects of Chemotherapy

China
Peking Union Medical College Hospital

Unknown

Vinorelbine-ifosfamide Versus Gefitinib for EGFR Gene Mutation Negative Non-small Cell Lung Cancer Patients

Non-small Cell Lung Cancer | Effects of Chemotherapy

China
Jazz Pharmaceuticals

Recruiting

Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Seizure in Participants With Tuberous Sclerosis Complex | Seizure in Participants With Dravet Syndrome | Seizure in Participants With Lennox-Gastaut Syndrome

United States
Centre Hospitalier Universitaire Vaudois
Swiss National Science Foundation

Recruiting

Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate

Kallmann Syndrome | Hypogonadotropic Hypogonadism | Hypothalamic Amenorrhea | Polycystic Ovarian Syndrome | Precocious Puberty | Cleft Lip and Palate | Cleft Palate | Cleft Lip

Switzerland
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
Chitwan Medical College

Completed

Cyclophosphamide Versus Mycophenolate Mofetil in Lupus Nephritis

To Compare the Effects of Mycophenolate Mofetil With Cyclophosphamide in Neplaese Lupus Nephritis Patients
Catholic University of the Sacred Heart
Fanfani, Francesco, M.D.; Fagotti, Anna, M.D.; Salvatore Gueli Alletti

Completed

Minimally Invasive Interval Debulking Surgery in Ovarian Neoplasm: a Feasibility Study (MISSION)

Peritoneal Cavity Cancer | Effects of Chemotherapy | Stage IV Ovarian Carcinoma

Italy
Assistance Publique - Hôpitaux de Paris

Completed

Transgender, Silicone and Blood Smear (TSBS)

Injection; Complications, Sepsis | Injection Site Disorder | Injection Site Extravasation | Intentional Poisoning by Silicone

France
University of Arizona
National Cancer Institute (NCI)

Completed

Moderate Physical Activity in Helping Patients Recover Physically and Emotionally From Stage II Or Stage III Colorectal Cancer

Depression | Colorectal Cancer | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy

Depression | Breast Cancer | Fatigue | Psychosocial Effects of Cancer and Its Treatment | Weight Changes

United States
University of California, Los Angeles
Northwestern University

Completed

Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy

Pain, Postoperative | Cerebral Palsy | Hip Dysplasia

United States
Odense University Hospital
Odense Patient Data Explorative Network

Completed

The Effect of Perioperative Dexamethasone Administration on Postoperative Pain in Patients Undergoing Periacetabular Osteotomy. (PAODEX)

Postoperative Pain | Hip Dysplasia | Postoperative Nausea and Vomiting | Dexamethasone

Denmark
Yale University

Withdrawn

Characterization of Diabetes Mellitus in Fibrous Dysplasia/McCune-Albright Syndrome

Diabetes Mellitus | Fibrous Dysplasia | McCune-Albright Syndrome | Intraductal Papillary Mucinous Neoplasm

United States
Cairo University

Recruiting

Relation Between Bone Mineral Density, Gross Motor Function and Quality of Life In Children With Cerebral Palsy

Cerebral Palsy | Gross Motor Development Delay | Bone Density, Low

Egypt
Washington University School of Medicine

Completed

A Wheelchair Propulsion Training Program (HS)

Multiple Sclerosis | Amputation | Spinal Cord Injuries | Spina Bifida

United States
National Institutes of Health Clinical Center (CC)

Terminated

Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Depression | Quality of Life | Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Nutrition | Psychosocial Effects/Treatment

United States
Diamyd Medical AB

Completed

Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease | Vitamin D | Autoimmune Diabetes | Physiological Effects of Drugs | Juvenile Diabetes | Insulin Dependent Diabetes

Czechia, Netherlands, Spain, Sweden
I.R.C.C.S. Fondazione Santa Lucia
IRCCS San Raffaele; Istituto Auxologico Italiano; University of Genova; IRCCS National... and other collaborators

Completed

Efficacy of Proprioceptive Focal Stimulation (EQUISTASI) on Gait Parameters in Parkinson. Italian Multicentric Study (PAGE)

Parkinson Disease | Gait, Shuffling | Effects of Vibration

Italy

Clinical Trials on Developmental Defects of Enamel

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CROs in Poland

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