Clinical Trials on Diabetes Mellitus

Total 20312 results

University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Diabetes | Cystic Fibrosis | Pancreatic Insufficiency | Abnormal Glucose Tolerance

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

β-cell Function and Insulin Sensitivity in Patients With Cystic Fibrosis

Cystic Fibrosis-related Diabetes
National Institute of Diabetes and Digestive and...

Recruiting

Diagnosis and Treatment of Patients With Cystic Fibrosis

Diabetes | Cystic Fibrosis | Liver Disease or Abnormalities | Pancreatic Insufficiency (Exocrine and Endocrine)

United States
University Hospitals Cleveland Medical Center

Completed

Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis (CFCGM)

Cystic Fibrosis | Hepatic Steatosis | Cystic Fibrosis-related Diabetes | Cystic Fibrosis Liver Disease | Pancreatic Steatosis

United States
Partners in Health
University of Warwick

Completed

Evaluating the Impact of a Community Health Worker Program in Neno, Malawi

Epilepsy | Hypertension | Diabetes | HIV/AIDS | Malnutrition | Asthma | Tuberculosis | Mental Health Disorder | Family Planning | Antenatal Care

Malawi
University of Utah

Recruiting

Effect of Sleep Extension on Ceramides in People With Overweight and Obesity

Sleep | Type 2 Diabetes | Sleep Deprivation | Overweight and Obesity | Insulin Sensitivity | Sleep Hygiene | Eating Habit | Lifestyle Factors | Insufficient Sleep Syndrome

United States
Centre Hospitalier National d'Ophtalmologie des...

Recruiting

Bimodal and Coaxial High Resolution Ophtalmic Imaging (AOSLO-OCT)

Stroke | Glaucoma | Hypertension | Diabetes | Retinal Degeneration | Macular Edema | Retinitis Pigmentosa | Retinal Detachment | Vascular Inflammation | Macular Dystrophy | Maculopathy, Age Related

France
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Japan
Poitiers University Hospital

Completed

Copeptin and the S-100b Protein in Stroke

Vertigo, Peripheral | Vertigo, Brain Stem | Vertigo; Central | Vertigo; Cerebral
Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
Istituto Ortopedico Galeazzi

Recruiting

Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty (GLICO PG)

To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients

Italy
Prim. Prof. Dr. Oliver Findl, MBA

Recruiting

Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug Injections

Age-related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion

Austria
Unity Biotechnology, Inc.

Completed

Safety and Tolerability Study of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Graybug Vision

Completed

A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Diabetic Macular Edema and Retinal Vein Occlusion

Diabetic Macular Edema | Retina Vein Occlusion

United States
California Retina Consultants

Completed

Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF

Age-related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion
Gulhane School of Medicine

Completed

Effect of Calcium Channel Blocker on the Serum Fibrobalst Growth Factor-23 (FGF-23) Levels in Type-2 Diabetic Patients With Proteinuria Purpose

We Searched for the Effects of Calcium Channel Blocker Amlodipine on the Clinical and Laboratory Parameters of Diabetic Patients With Proteinuria.

Turkey
IRCCS SYNLAB SDN
Federico II University

Recruiting

Potential Role of Sirtuins as Epigenetic Biomarkers of the Patient With Atherosclerosis or Calcific Aortic Stenosis

Atherosclerosis and Calcific Aortic Stenosis With and Without Diabetes

Italy
University of Texas Southwestern Medical Center
University of North Carolina, Chapel Hill

Recruiting

DIALYSIS-TIR Study

Type 2 Diabetes | End Stage Renal Disease on Dialysis

United States
BRAC University

Active, not recruiting

Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh

Hypertension | Diabetes | Asthma | Chronic Obstructive Pulmonary Disease (COPD)

Bangladesh
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Completed

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
RenJi Hospital

Recruiting

Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture

Patients With an Abdominal Aortic Aneurysm of 39-49 mm in Diameter

China
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KINGFISHER)

Diabetic Macular Edema

United States, Hungary, Israel, Slovakia, Puerto Rico
Novartis Pharmaceuticals

Completed

A 12-month, Randomized, Efficacy and Safety Study of 0.5 mg Ranibizumab vs Laser in Chinese Diabetic Macular Edema (DME) Patients (REFINE)

Diabetic Macular Edema | Visual Impairment

China
University at Buffalo
Solvay Pharmaceuticals

Terminated

Effect of Androgel on Atherogenesis in Type 2 Diabetic Males With Hypogonadotrophic Hypogonadism

Type 2 Diabetic Male With Hypogonadotrophic Hypogonadism

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Johns Hopkins University
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities (LINKED-HEARTS)

Hypertension | Diabetes | Chronic Kidney Diseases | High Blood Pressure

United States
National Human Genome Research Institute (NHGRI)

Recruiting

Caregiving Networks Across Disease Context and the Life Course

Diabetes | Undiagnosed Diseases | Inherited Metabolic Disorders | Batten's Disease | Tay Sachs

United States
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH

Antidiuretic Hormone, Inappropriate Secretion

Japan
Changhai Hospital

Recruiting

Artificial Intelligence-based Early Screening of Pancreatic Cancer and High Risk Tracing (ESPRIT-AI) (ESPRIT-AI)

Diabetes | Pancreatic Cancer | Chronic Pancreatitis | Familial Pancreatic Cancer | Pancreatic Cystic Neoplasm | Hereditary Pancreatitis

China
Harvard School of Public Health (HSPH)
National Heart, Lung, and Blood Institute (NHLBI); National Institute on Minority... and other collaborators

Recruiting

Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico (PROSPECT)

Heart Diseases | Cardiovascular Diseases | Inflammation | Hypertension | Obesity | Metabolic Syndrome | Dyslipidemias | Chronic Disease | Depressive Symptoms | Type2 Diabetes | Coping Behavior | Diet Habit | Psychological Stress | Lifestyle | Physiological Stress

Puerto Rico
University of Illinois at Chicago
National Institute on Aging (NIA)

Completed

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease) | Uncontrolled Diabetes (HBA1c ≥ 10)

United States
Eurasian Association of Therapists

Completed

Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection (ACTIV-2)

Diabetes | Covid19 | Death | Atrial Fibrillation | Risk Factor, Cardiovascular | CKD | COPD | Comorbidities and Coexisting Conditions | DVT

Russian Federation
University of Pennsylvania

Completed

Developing Enhanced Prediction Models (PREDICT)

Pneumonia | Diabetes | Chronic Obstructive Pulmonary Disease (COPD) | Congestive Heart Failure (CHF) | Acute Myocardial Infraction or Chest Pain

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Diabetes | Mortality | Body Weight | Metabolic Syndrome | Dyslipidemias | PreDiabetes | Hyperlipidemias | Coronary Heart Disease | Overweight and Obesity | Obesity, Abdominal | Dysglycemia | Insulin Tolerance

Canada
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Study to Determine the Efficacy of Real-time CGM in Preventing Hypoglycemia Among Insulin-treated Patients With DM2 on Hemodialysis, Compared to Standard of Care (POC BG)

Type 2 Diabetes | End-Stage Renal Disease

United States
Weill Medical College of Cornell University
Patient-Centered Outcomes Research Institute

Completed

Comparative Effectiveness of Telemedicine in Primary Care

Hypertension | Diabetes | Asthma | Congestive Heart Failure | Chronic Obstructive Pulmonary Disease (COPD

United States
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-analyses of Fructose and Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Non-alcoholic Fatty Liver Disease | Prediabetes | Gout | Dysglycemia

Canada
University Hospital, Basel, Switzerland
Kantonsspital Aarau

Completed

Copeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water Homeostasis

Pituitary Adenoma

Switzerland
Unity Health Toronto

Recruiting

Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept (COVARIANT)

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

Canada
Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

United States, Puerto Rico
Centre Hospitalier Universitaire Dijon

Completed

Impact of COVID-19 Infection and Confinement on Diabetic Ulcer Management and Amputation Risk (COROPIEDIAB)

Diabetic Subjects With Hospital Stays

France
Justis Ehlers
Regeneron Pharmaceuticals

Completed

Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO (PERMEATE)

Central Retinal Vein Occlusion | Diabetic Macular Edema | Retinal Vein Occlusion | Branch Retinal Vein Occlusion

United States
Bausch & Lomb Incorporated

Completed

Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium

Age-Related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion

United States
Bulent Ecevit University

Completed

Effect of Dexamethasone Implant on Optic Disc

Diabetic Macular Edema | Intravenous Drug Usage | Glaucoma and Ocular Hypertension | Optic Disk Disorders

Turkey
Wills Eye
Mid Atlantic Retina

Completed

30g vs 33g Needle for Intravitreal Injections

Diabetic Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

United States
Unity Health Toronto

Recruiting

Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab (COVERT)

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

Canada
Wills Eye
Mid Atlantic Retina; J. Arch McNamara Research Fund

Completed

Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.

Age-related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion | Wet Macular Degeneration

United States
Retina Vitreous Associates of Florida

Completed

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

Age-related Macular Degeneration | Central Retinal Vein Occlusion | Diabetic Macular Edema

United States
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany

Clinical Trials on Diabetes Mellitus

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CROs in Mauritius

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