Clinical Trials on Diabetic Polyneuropathy in South Africa

Total 1054 results

Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy

United States
Sangamo Therapeutics
Juvenile Diabetes Research Foundation

Completed

Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Polyneuropathy

United States
University of Pretoria
South African Sugar Association

Completed

Nutrition Education Intervention for Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa
Wits Health Consortium (Pty) Ltd
Discovery Vitality

Active, not recruiting

Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits Amongst Individuals With Risk Factors for Diabetes

Type 2 Diabetes | Pre-diabetes

South Africa
Lannett Company, Inc.
Parexel; FARMOVS (Pty) Ltd

Completed

A Study to Demonstrate Pharmacokinetic and Pharmacodynamic Biosimilarity Between HEC-Glargine and US-Lantus® in Healthy Male Volunteers

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

South Africa
Eli Lilly and Company

Completed

A Study to Compare the Pharmacokinetics and Pharmacodynamics of LY2963016 to Lantus in Healthy Participants

Diabetes Mellitus

South Africa
University of Pretoria

Unknown

The Efficacy of Specialist Collaboration and Mobile Screening for Improving the Management of Diabetes (CCMSD)

Diabetes

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
University of Witwatersrand, South Africa
GlaxoSmithKline; University of Oxford; Medical Research Council, South Africa; University...

Completed

Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women

Diabetes Mellitus, Type 2 | Insulin Resistance | Menopause | Hiv

South Africa
University of Pretoria
Nestlè Nutrition Institute Africa; South African Sugar Association

Completed

Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting

Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
Prosidion Ltd.

Completed

A PK-PD Study of PSN821 in Type 2 Diabetes Patients (T2DM)

Type 2 Diabetes Mellitus

South Africa
Boston University
World Bank (Lead institution); Republic of South Africa National Department...

Completed

Evaluation of South Africa's National Adherence Strategy (ENHANCE)

Hypertension | Diabetes | HIV | Tuberculosis

South Africa
Foundation for Innovative New Diagnostics, Switzerland
University of Cape Town; The Leona M. and Harry B. Helmsley Charitable Trust; University of Pretoria

Recruiting

Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa (ACCEDE)

Type 1 Diabetes

South Africa
Novo Nordisk A/S

Completed

Long Term Safety of Biphasic Insulin Aspart 30 in Juveniles With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

South Africa
University of KwaZulu
Cambridge University Hospitals NHS Foundation Trust; University of Oxford; University...

Completed

Durban Diabetes Study:A Study of the Epidemiology of Diabetes Mellitus in Urban South Africans of African Descent (DDS) (DDS)

Hyperglycemia | Diabetes Mellitus | Glucose Intolerance | Hereditary Diseases

South Africa
TaiGen Biotechnology Co., Ltd.

Completed

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

Diabetic Foot Infections

Taiwan, United States, South Africa, Thailand
Novo Nordisk A/S

Completed

Safety and Efficacy of Biphasic Human Insulin Compared to EX1000 in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

South Africa, United Arab Emirates, India
Yaounde Central Hospital
University of Exeter; University of Yaounde 1; MRC/UVRI & LSHTM Uganda Research...

Recruiting

Characteristics of Young-onset Diabetes in Sub-Saharan Africa (YODA) Study (YODA)

Type 1 Diabetes | Diabetes, Autoimmune

Tanzania, Cameroon, South Africa, Uganda
RedDress Ltd.

Completed

Safety and Efficacy of ActiGraft Compared to Standard of Care in DFUs

Diabetic Foot | Chronic Ulcer

United States, South Africa, Turkey
Carolina Musculoskeletal Institute
Baylor University; Pamlab, L.L.C.

Completed

Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®

Diabetic Peripheral Neuropathy

United States
University of Sydney
Allergan

Completed

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema (SwitchDMO)

Diabetes | Diabetic Retinopathy | Diabetic Macular Edema | Diabetic Macular Oedema

Australia
Medical University of South Carolina

Completed

Impact of Vitamin D on Diabetic Kidney Disease in African Americans

Diabetic Kidney Disease

United States
Abbott Products
Quintiles, Inc.

Completed

A Safety PK/PD Study of SLV337 in Patients With Type 2 Diabetes

Type 2 Diabetes

Bulgaria, Poland, South Africa
University of Sydney
National Health and Medical Research Council, Australia; Mylan Pharmaceuticals... and other collaborators

Recruiting

The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. (FAME 1 EYE)

Diabetic Retinopathy | Diabetic Nephropathies | Type 1 Diabetes Mellitus

Australia, Hong Kong, New Zealand
Prisma Health-Upstate

Terminated

Diabetic Foot Infection Antibiotic Study

Diabetic Foot Infections

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Diabetes UK

Completed

Study of CBME in the Relief of Painful Diabetic Neuropathy

Diabetic Neuropathy | Painful

United Kingdom
Sanofi

Completed

Evaluation of the Blood Levels of the Drug (Lixisenatide), the Plasma Glucose Levels and Safety in Paediatric and Adult Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Mexico, United Kingdom
Prisma Health-Midlands

Terminated

Immunonutrition for Diabetic Foot Ulcers

Diabetes Mellitus | Diabetic Foot Ulcer | Diabetic Peripheral Neuropathy

United States
Novo Nordisk A/S

Completed

A Survey on Low Blod Sugar Among Insulin-treated Patients With Diabetes

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Turkey, Egypt, Philippines, United Arab Emirates, Bangladesh, Colombia, Singapore, South Africa
University of Sydney
Center for Eye Research Australia

Completed

Laser Therapy Combined With Intravitreal Aflibercept vs Intravitreal Aflibercept Monotherapy (LADAMO) (LADAMO)

Diabetic Retinopathy

Australia
Eli Lilly and Company

Completed

Safety, Tolerability, and Effect of LY2405319 After Multiple Injections in Subjects With Type 2 Diabetes

Type 2 Diabetes

India, Mexico, New Zealand, South Africa
Cynata Therapeutics Limited

Recruiting

Safety, Tolerability and Efficacy of CYP-006TK in Adults With Diabetic Foot Ulcers

Diabetic Foot Ulcer | Cutaneous Ulcer

Australia
BioChemics, Inc.
Harrison Clinical Research

Withdrawn

Safety and Efficacy Study of BC-DN-01 in Painful Diabetic Peripheral Neuropathy

Diabetic Neuropathy, Painful

United Kingdom
University of KwaZulu
King's College London; University of Oxford; University of East Anglia; University... and other collaborators

Recruiting

ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE (ENHANCE)

Depression | Myocardial Infarction | HIV Infections | Stroke | Hypertension | Diabetes Mellitus | Asthma

South Africa
Retina Macula Specialists of Miami, LLC
Allergan

Unknown

Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME (ICOD)

Diabetic Retinopathy | Diabetic Macular Edema | Retinal Ischemia

United States
Eli Lilly and Company

Completed

Lispro Mid Mixture (MM) Intensive Mixture Therapy With Progressive Dose-Titration of Lispro Low Mixture (LM) or Biphasic Insulin Aspart 30/70 (S019) (S019)

Diabetes Mellitus, Type 2

Croatia, Poland, Romania, South Africa, Turkey
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN)

Diabetic Peripheral Neuropathy

United States, Czechia, Sweden, South Africa
Sanofi

Completed

Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin Treatment

Type 2 Diabetes Mellitus

France, Poland, Germany, Italy, Netherlands, Belgium, Denmark, Chile, South Africa, Australia, Argentina
Synvista Therapeutics, Inc
Juvenile Diabetes Research Foundation

Terminated

Study of Alagebrium in Patients With Insulin-Dependent Type 1 Diabetes and Microalbuminuria

Diabetes Mellitus, Type 1 | Diabetic Nephropathy

Australia, Denmark
Novo Nordisk A/S

Completed

Safety of Insulin Detemir Produced by a New Process as Measured by Antibody Formation in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Germany, South Africa, Russian Federation, Former Serbia and Montenegro, North Macedonia
Xequel Bio, Inc.
Medical University of South Carolina; Spartanburg Regional Healthcare System

Completed

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
Rafic Hariri University Hospital
American University of Beirut Medical Center

Unknown

Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study (ADA01)

Uveitis | Diabetic Retinopathy | Choroidal Neovascularization

Lebanon
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Diabetic Retinopathy | Vitreous Hemorrhage

Spain, Australia, United Kingdom, Brazil, Hungary, Italy, Netherlands, Poland, South Africa
The George Institute

Not yet recruiting

Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis (BEST-DKA)

Diabetic Ketoacidosis

Australia
Chonbuk National University Hospital

Completed

Efficacy of γ-linolenic Acid and Thioctic Acid in Patients With Diabetic Neuropathy

Diabetic Neuropathy

Korea, Republic of
Ethicon, Inc.

Completed

Evaluation of the Clinical Effectiveness of a Collagen-ORC Antimicrobial Matrix in Full-Thickness, Neuropathic Diabetic Foot Ulcers

Foot Ulcer

United States
Sanofi

Completed

Evaluation of the Efficacy and Safety of Insulin Glargine 300 U/mL in Patients With Type 2 Diabetes Mellitus Uncontrolled on Other Kinds of Insulin (ARTEMIS-DM)

Type 2 Diabetes Mellitus

Argentina, Colombia, Egypt, Hong Kong, India, Indonesia, Lebanon, Malaysia, Peru, Philippines, Saudi Arabia, South Africa, Thailand, Turkey

Clinical Trials on Diabetic Polyneuropathy in South Africa

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