Clinical Trials on Digestive Tract Cancer in United States

Total 63175 results

Nadine McCleary, MD, MPH
Bristol-Myers Squibb

Recruiting

SURGE: Supporting UnderRepresented Minorities in Genomics-based Cancer Trial Enrollment (Intervention)

Thoracic Cancer | Gastrointestinal Cancer | Hematologic Cancer

United States
TransThera Sciences (Nanjing), Inc.

Completed

Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

Sarcoma | Gastric Cancer | Prostate Cancer | Cholangiocarcinoma | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Small-cell Lung Cancer | Thyroid Cancer | Gallbladder Cancer | HER2-negative Breast Cancer

United States
Tulane University School of Medicine
Robert Wood Johnson Foundation

Completed

Using Effective Provider-Patient Communication to Improve Cancer Screening Among Low Literacy Patients

Cervical Cancer | Breast Cancer | Colorectal Cancer

United States
Inova Health Care Services
University of Houston; University of Louisville; Howard University; Tigerlily Foundation and other collaborators

Active, not recruiting

Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention (MOM)

Melanoma | Cancer | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Esophageal Cancer | Lung Cancer | Brain Cancer | Gastrointestinal Cancer | Central Nervous System Cancer | Acceptance and Commitment Therapy | Blood Cancer | Genitourinary Cancer | Psychosocial Intervention | Mind-Body Therapies

United States
MedImmune LLC

Completed

A Phase 1/2 Study of MEDI4276 in Adults Subjects With Select HER2-expressing Advanced Solid Tumors. (MEDI4276)

HER2 Expressing Breast or Gastric/Stomach Cancers

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer

Metastatic Colorectal Cancer | Colorectal Cancer | Colon Cancer

United States
University of Nebraska
National Cancer Institute (NCI); Adherex Technologies, Inc.

Completed

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Pancreatic Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage IIIA Gallbladder Cancer | Stage IIIB Gallbladder Cancer | Stage IVA Gallbladder Cancer | Stage IVB Gallbladder Cancer | Gallbladder Adenocarcinoma and other conditions

United States
Memorial Sloan Kettering Cancer Center

Completed

Person-Centered Oncology Care and Choices (P-COCC): Piloting and Initial Randomized Testing of a Combined Values Narrative Interview and Video Education Advance Care Planning Program in Gastrointestinal Oncology Patients

Advanced Gastrointestinal Cancer

United States
University of California, San Francisco
Centers for Disease Control and Prevention; San Francisco Department of Public...

Completed

The FLU-FOBT Program in Primary Care Settings Where Disparities Persist

Colorectal Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

A Study of Patients Receiving High-Dose Rate Brachytherapy

Cervical Cancer | Esophageal Cancer | Prostate Cancer | Endometrial Cancer | Biliary Cancer

United States
NYU Langone Health
Food and Drug Administration (FDA)

Completed

Adjuvant Intraperitoneal Floxuridine Added to Chemoradiation for Fully Resected Advanced Stomach Cancer

Stomach Cancer | Gastric Cancer

United States
NYU Langone Health
Bristol-Myers Squibb; Eli Lilly and Company

Completed

Pre-operation Chemo and Antibody Therapy Followed by Surgical Resection and Adjuvant Chemoradiation for Gastric Cancer

Stomach Cancer | Gastric Cancer

United States
NYU Langone Health

Withdrawn

KD019 and Trastuzumab in Patients With Esophagus, Gastroesophageal Junction and Stomach Cancer

Stomach Cancer | Esophageal Cancer

United States
NYU Langone Health

Completed

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Gastric Cancer | GastroEsophageal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Heat Therapy in Treating Patients With Unresectable Primary or Metastatic Liver Cancer

Metastatic Cancer | Liver Cancer

United States
National Cancer Institute (NCI)

Terminated

BMS-247550 in Treating Patients With Liver or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Extrahepatic Bile Duct Cancer | Localized Gallbladder Cancer | Localized Resectable Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent... and other conditions

United States
Inovio Pharmaceuticals
Mayo Clinic; University of Pennsylvania; University of Pittsburgh; Thomas Jefferson... and other collaborators

Completed

hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse (TRT-001)

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | ColoRectal Cancer | HepatoCellular Carcinoma

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); University of Massachusetts, Boston

Recruiting

Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study

Breast Cancer | Colorectal Cancer | Prostate Cancer

United States
Siemens Molecular Imaging

Completed

Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic Drug (K5-101)

Non-squamous Non-small Cell Lung Cancer | Metastatic Breast Cancer | Metastatic Colon/Rectum Cancer

United States
Pennington Biomedical Research Center
National Cancer Institute (NCI)

Active, not recruiting

The Exercise And Colorectal Cancer Treatment Trial (EXACT)

Rectal Cancer | Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Bryostatin 1 and Cisplatin in Treating Patients With Metastatic or Unresectable Stomach Cancer

Stage IV Gastric Cancer | Stage III Gastric Cancer

United States
The Miriam Hospital

Completed

Promoting Physical Activity After Colorectal Cancer

Rectal Cancer | Colon Cancer

United States
Duke University

Recruiting

Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers

Esophageal Cancer | Vulvar Cancer | Anal Canal Cancer | Cancer of the Cervix

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

M1231 in Participants With Solid Tumors

Esophageal Cancer | Non-Small Cell Lung Cancer | Metastatic Solid Tumors

United States, Canada
University of Southern California
National Cancer Institute (NCI); Sanofi

Terminated

Cabazitaxel Plus Prednisone With Octreotide For Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel

Diarrhea | Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IV Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
AstraZeneca

Active, not recruiting

Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) (TOPAZ-1)

Biliary Tract Neoplasms

France, Italy, United States, Thailand, Korea, Republic of, United Kingdom, India, Japan, Poland, Russian Federation, Turkey, China, Taiwan, Hong Kong, Chile, Bulgaria, Argentina
Dana-Farber Cancer Institute
Sanofi

Completed

Prospective Analysis of Hypersensitivity Reactions to Oxaliplatin

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Baylor College of Medicine
Genentech, Inc.

Not yet recruiting

Neoadjuvant Chemoimmunotherapy for Resectable Non-Metastatic Proficient Mismatch Repair (PMMR) Colon Cancer

Stage I Colon Cancer | Stage II Colon Cancer | Stage III Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Pancreas Cancer | Cancer of Pancreas | Cancer of the Pancreas

United States
Abramson Cancer Center at Penn Medicine

Recruiting

CTNNA1 Familial Expansion Study (CAFÉ)

Breast Cancer | Gastric Cancer | Cancer Gene Mutation

United States
Johns Hopkins University
Krames Staywell Corporation

Completed

Johns Hopkins Interactive eGuide to Colonoscopy and Ipad Office Education to Improve Colonoscopy

Colon Cancer Screening | Colon Cancer Surveillance

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Dartmouth-Hitchcock Medical Center; West Virginia... and other collaborators

Active, not recruiting

Symptom Management Implementation of Patient Reported Outcomes in Oncology (SIMPRO)

Gynecologic Cancer | Thoracic Cancer | Gastrointestinal Cancer | Other Cancer

United States
Ajeet Gajra
Merck Sharp & Dohme LLC

Unknown

Study Assessing Fosaprepitant in Advanced NSCLC Patients Treated With Carboplatin Based Chemotherapy

Nausea | Vomiting | Non-small Cell Lung Cancer | Emesis

United States
Georgetown University
National Cancer Institute (NCI)

Completed

Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors

Breast Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
M.D. Anderson Cancer Center

Active, not recruiting

Glutamine PET Imaging Colorectal Cancer

Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | RAS Wild Type

United States
Ludwig Institute for Cancer Research
Cancer Research Institute, New York City; MedImmune LLC; Targovax ASA

Completed

A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies

Colorectal Cancer | Ovarian Cancer | Appendiceal Cancer

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Genentech, Inc.; SCRI Development Innovations... and other collaborators

Completed

Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

Stomach Cancer | Gastric Cancer | Esophageal Cancer

United States
Legacy Health System

Completed

Effectiveness of High Dose Vitamin D Supplementation in Stage III Colorectal Cancer

Rectal Cancer | Colon Cancer

United States
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Glioblastoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Advanced Solid Tumors | Triple Negative Breast Cancer | Biliary Tract Cancers

United States, Argentina, Australia, Canada, Chile, Colombia, France, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, Switzerland, Taiwan, Thailand, United Kingdom
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Stent Placement With or Without Photodynamic Therapy Using Porfimer Sodium as Palliative Treatment in Treating Patients With Stage III or Stage IV Cholangiocarcinoma That Cannot Be Removed By Surgery

Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder

United States, Canada
National Cancer Institute (NCI)

Completed

Topotecan and Radiation Therapy in Treating Patients With Solid Tumors or Lymphoma

Lymphoma | Esophageal Cancer | Lung Cancer

United States
AstraZeneca

Completed

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors

Spain, United States, Canada
Alaunos Therapeutics
M.D. Anderson Cancer Center

Suspended

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Ovarian Cancer | Cholangiocarcinoma | Endometrial Cancer | Non-small Cell Lung Cancer | Pancreas Cancer | Colo-rectal Cancer

United States
NuCana plc

Terminated

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

Canada, United States, Spain, Hungary, Korea, Republic of, United Kingdom, Czechia, Germany, Russian Federation, Australia, France, Taiwan, Ukraine, Italy, Turkey
Washington University School of Medicine

Recruiting

Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer

Esophageal Cancer | Cancer of the Esophagus | Esophagus Cancer

United States
Memorial Sloan Kettering Cancer Center
Sirtex Medical

Completed

Selective Internal Radiation Therapy (SIRT) in Patients With Unresectable Colorectal Cancer Liver Metastases Who Failed Prior Intraarterial Pump Chemotherapy

Rectal Cancer | Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer

Stage II Colon Cancer | Stage III Colon Cancer

United States
University of Wisconsin, Madison

Terminated

Pilot Study of 18F-FLT PET

Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Prostate Cancer | CNS Brain Metastasis

United States
University of Maryland, Baltimore
National Cancer Institute (NCI)

Completed

LMB-9 Immunotoxin in Treating Patients With Advanced Colon, Breast, Non-small Cell Lung, Bladder, Pancreatic, or Ovarian Cancer

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Bladder Cancer

United States

Clinical Trials on Digestive Tract Cancer in United States

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