Clinical Trials on Dominant Optic Atrophy

Total 4101 results

Nemours Children's Clinic

Recruiting

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Charcot-Marie-Tooth Disease | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Muscular Atrophy | Neuromuscular Disease | Spinal Muscular Atrophy With Respiratory Distress 1 | Peroneal Muscular Atrophy

United States
Hugh Taylor

Recruiting

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

Asherman Syndrome | Recurrent Implantation Failure | Atrophic Endometrium

United States
I.M. Sechenov First Moscow State Medical University

Recruiting

Increasing the Thickness of Soft Tissues in the Esthetic Zone Around Implants

Soft Tissue Atrophy

Russian Federation
University Hospital, Ioannina

Completed

Fractional Laser Drug Delivery of a Local Anesthetic

Aging | Face; Atrophy

Greece
I.M. Sechenov First Moscow State Medical University

Active, not recruiting

Clinical and Histological Outcomes of Using Collagen Matrix or Soft Tissue Graft Around Implants

Soft Tissue Atrophy

Russian Federation
Duke University

Withdrawn

Modeling the Effects of Vocal Cord Atrophy on Airflow and Voice Quality in Elderly Individuals

Vocal Cord Atrophy

United States
Fidia Farmaceutici s.p.a.

Completed

Efficacy and Safety of HYDEAL-D Vaginal Pessaries Application on the Treatment of Vaginal Atrophy in Post-menopause Women

Vulvovaginal Atrophy

Slovakia
Dr. Lila Nachtigall Rapid Medical Research, New...
Se-cure Pharmaceuticals Ltd.

Completed

A Twelve Week Study to Investigate the Efficacy of Femarelle®, for the Treatment of Post Menopausal Vaginal Atrophy

Vulvo Vaginal Atrophy

United States
PepTonic Medical AB

Completed

Study of Oxytocin to Treat Vaginal Atrophy in Postmenopausal Women

Vaginal Atrophy | Postmenopause

Sweden, United Kingdom
Sohag University

Recruiting

Expression of PARP-1 in Multiple Sclerosis Patients

Multiple Sclerosis

Egypt
Kyorin University

Completed

Vitrectomy for Optic Disc Pit Maculopathy

Optic Disc Pit Maculopathy

Japan
University of Birmingham

Active, not recruiting

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Wolfram Syndrome

France, United Kingdom, Poland, Spain
Connecticut Children's Medical Center
University of Connecticut

Recruiting

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

Anterior Cruciate Ligament Injuries | Knee Injuries | Quadriceps Muscle Atrophy

United States
Amsterdam UMC, location VUmc

Completed

Expiratory Muscle Function in Critically Ill Ventilated Patients (EMFIC)

Critical Illness | Muscle Atrophy or Weakness | Mechanical Ventilation | Diaphragm | Expiratory Muscle

Netherlands
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
Lawson Health Research Institute

Not yet recruiting

The Fat Analysis Trial (FAT) - Assessing the Impact of Lipo-aspirate Processing

Breast Asymmetry | Fat Atrophy
Daré Bioscience, Inc.

Completed

Study of DARE-HRT1 Over 12 Weeks in Healthy PostMenopausal Women (DARE-HRT1)

Vasomotor Symptoms | Vulvovaginal Atrophy

Australia
University Hospital Inselspital, Berne
Medinova AG

Completed

Sustainability of Vaginal Estrogen Therapy in Postmenopausal Women

Postmenopause | Atrophy of Vagina

Switzerland
Viramal Limited

Completed

Exploratory Study on Two Different Doses of VML-0001 on the Effects on Vaginal pH in Healthy Post-Menopausal Women

Vaginal Atrophy

United States
University of Pittsburgh

Completed

Volumetric Analysis in Autologous Fat Grafting to the Foot

Pedal Fat Pad Atrophy

United States
Assistance Publique - Hôpitaux de Paris

Completed

Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor (Es-Alert)

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy

France
AveXis, Inc.
United BioSource, LLC

Recruiting

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA)

Japan, United States, Korea, Republic of, Israel, Greece, Ireland, Portugal, Russian Federation, Taiwan
Chinese University of Hong Kong

Recruiting

The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures

Anterior Cruciate Ligament Injuries | Quadriceps Muscle Atrophy

Hong Kong
Aviceda Therapeutics, Inc.

Recruiting

A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) (SIGLEC)

Macular Degeneration | Geographic Atrophy of the Macula

United States
University of Nottingham
University of Oxford

Recruiting

Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune) (Rapamune)

Muscle Atrophy | Age-Related Sarcopenia

United Kingdom
University of Exeter

Completed

Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.

Muscle Atrophy

United Kingdom
High Point Pharmaceuticals, LLC.

Terminated

Safety Study of HPP593 in Subjects During and After Limb Immobilization

Muscle Atrophy | Hypodynamia

United States
Catalyst Pharmaceuticals, Inc.

Terminated

Long Term Safety of Amifampridine Phosphate in Spinal Muscular Atrophy 3 (SMA3)

Spinal Muscular Atrophy Type 3

Italy
Peking University People's Hospital
Chinese Association of Plastics and Aesthetics

Recruiting

Evaluating the Efficacy of Temperature-controlled Radiofrequency (TRF) in the Treatment of Vulvovaginal Atrophy.

Postmenopausal Vulvovaginal Atrophy

China
Venus Concept

Completed

Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction

Adipose Tissue Atrophy

United States
University of Valencia

Completed

Effects of Suspension Training in Older Adults

Old Age; Atrophy

Spain
I.M. Sechenov First Moscow State Medical University

Active, not recruiting

Comparative Analysis Using the Collagen Matrix and Autogenous Graft: Clinical Course, Aesthetic Results

Soft Tissue Atrophy

Russian Federation
Venus Concept
University of Texas

Enrolling by invitation

Analysis of the Performance of 1060 nm Diode and Radio Frequency Prior to Abdominoplasty

Adipose Tissue Atrophy

United States
Warner Chilcott

Completed

Safety & Efficacy WC3011 (Estradiol Vaginal Cream) in the Treatment of Vulvovaginal Atrophy in Postmenopausal Women (VENUS)

Postmenopausal Vulvovaginal Atrophy

United States
Basque Health Service

Completed

Clinical Applicability of the Device Belk in the Rehabilitation Process

Application Site Atrophy

Spain
Cairo University

Unknown

Cyanoacrylate With Sutures for Fixation of Free Gingival Graft

Soft Tissue Atrophy
The University of Hong Kong

Unknown

Ving Tsun Martial Exercise for Older Adults

Old Age; Atrophy

Hong Kong
Seoul National University Hospital

Completed

Efficacy and Safety Study of EVERA to Augment Small Breast

Atrophy of Breast

Korea, Republic of
Steadman Philippon Research Institute

Withdrawn

BFR Therapy After ACL Reconstruction (BFR)

ACL Injury | Quadriceps Muscle Atrophy

United States
Calcilytix Therapeutics, Inc., a BridgeBio company

Recruiting

ADH1 and ADH2 Disease Monitoring Study (DMS) (CLARIFY)

Autosomal Dominant Hypocalcemia

United States, France, Denmark, Australia, Japan, Belgium, Canada, Italy, Netherlands, United Kingdom, Portugal, Finland, Germany
Kadmon, a Sanofi Company

Completed

A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

United States
Carolina Cannillo

Completed

The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Denmark
Pfizer

Completed

Bosutinib For Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

United States, Canada, Australia, Sweden, Spain, Poland, Korea, Republic of, Switzerland, United Kingdom, Moldova, Republic of, Italy, Czech Republic, Hungary, Lithuania, Romania, Slovakia, Turkey
Radboud University Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease (CURSOR)

Polycystic Kidney, Autosomal Dominant | Polycystic Liver Disease

Netherlands, Spain
Ludwig-Maximilians - University of Munich

Completed

Natural History in CCFDN and IBM Syndromes

Inclusion Body Myositis, Sporadic | Inclusion Body Myopathy, Autosomal-recessive | Inclusion Body Myopathy, Autosomal-dominant | Congenital Cataracts, Facial Dysmorphism, And Neuropathy

Germany
Otsuka Pharmaceutical Co., Ltd.

Completed

Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD

Polycystic Kidney, Autosomal Dominant

Japan
Otsuka Pharmaceutical Development & Commercialization...

Completed

Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Italy, Spain, Sweden, United States, Canada, Australia, Netherlands, Czechia, Poland, Denmark, Israel, Hungary, Russian Federation, South Africa, United Kingdom, Romania, Argentina, Norway
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Canada, Brazil, Taiwan, Singapore, South Africa, United Kingdom
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Faculdade de Ciências Médicas da Santa Casa de...

Recruiting

Efficacy of the Aussie Current in Patients With Knee Osteoarthritis.

Osteoarthritis, Knee | Quadriceps Muscle Atrophy

Brazil

Clinical Trials on Dominant Optic Atrophy

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