Clinical Trials on Drug Safety ; Drug Specificity

Total 3107 results

Daiichi Sankyo, Inc.

Completed

Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subjects

Drug Interaction

United Kingdom
Natalia Valadares de Moraes
Hospital das Clínicas de Ribeirão Preto

Unknown

Genetic Polymorphisms of ABCG2/BCRP on the Transport of Nifedipine to Breast Milk.

Drug Transporter
Biogen

Completed

A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen

Drug Interactions

United States
Biogen

Completed

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

Drug Interaction

United States
GlaxoSmithKline

Completed

Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation

Drug Interactions

Korea, Republic of
Gerd Mikus

Completed

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Drug Interactions

Germany
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
Lexicon Pharmaceuticals

Completed

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions

United States
University of Michigan
National Institute on Drug Abuse (NIDA)

Completed

F.Y.I.: Flint Youth Injury Study (FYI)

Drug Usage

United States
Ajou University School of Medicine

Completed

Dosing Study of Remifentanil for Smooth Removal of the Laryngeal Mask Airway (LMA)

Drug Usage

Korea, Republic of
Ajou University School of Medicine

Completed

Dexmedetomidine for Laryngeal Mask Airway Insertion

Drug Usage

Korea, Republic of
Gebro Pharma GmbH

Completed

S(+)-Ibuprofen Effects on Asprin Treated Volunteers

Drug Interactions

Austria
AstraZeneca

Completed

A Drug-Drug Interaction Study Between AZD1981 and Pravastatin to Study the Effect of AZD1981 on the Kinetics of Pravastatin

Drug Interaction

Sweden
Universidad Nacional de Córdoba

Unknown

Study for Early Detection of Drug Interactions in Older Hospitalized Patients Using on Line Software (SEDDI)

Drug Interactions

Argentina
University of Sao Paulo
AstraZeneca

Unknown

Evaluation of Bacterial and Fungal Contamination During Propofol Continuous Infusion

Drug Contamination

Brazil
University of Aarhus
Danish Research Agency

Completed

Danish Aspirin Resistance Trial - Pilot Study

Drug Resistance

Denmark
University Hospital Inselspital, Berne

Completed

Effect of Fluvastatin on Top of Clopidogrel and Aspirin in Patients After DES Implantation on Platelet Aggregation (EFA-1)

Drug-Interactions

Switzerland
University of Cape Town
Medical Research Council, South Africa

Completed

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis (NAC in TB DIH)

Drug-Induced Liver Injury

South Africa
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
University Hospital, Antwerp
Universiteit Antwerpen; AZ Jan Palfijn Gent

Not yet recruiting

Diagnosing Drug Allergy: the T is the Key (TAT)

Amoxicillin Allergy
Renaissance RX
Syntactx

Unknown

Diagnosing Adverse Drug Reactions Registry (DART)

Genetics of Drug Metabolism

United States
Karolinska Institutet
Region Stockholm

Completed

Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients

Polypharmacy | Adverse Drug Reaction

Sweden
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Drug-drug Interaction,SHR3680

China
London School of Hygiene and Tropical Medicine
Université de Thies, UFR Santé, Senegal

Active, not recruiting

Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children (MALHELMIN)

Malaria | Schistosomiasis | Soil Transmitted Helminths | Integrated Control | Seasonal Malaria Chemoprevention | Mass Drug Administration With Anthelminthic Drugs

Senegal
University of Rochester
Agency for Healthcare Research and Quality (AHRQ)

Completed

Emergency Pharmacist Safety Study

Adverse Drug Event, Potential Adverse Drug Event, and Quality Measures

United States
Direction Centrale du Service de Santé des Armées

Recruiting

Alleged Drug Allergies in Military General Medicine: Patients' Experiences and Beliefs (ALLMED)

Allergy Penicillin

France
Assiut University

Unknown

Effect Of DAAs For Treatment Of HCV On Normal Kidney

Antiviral Drug Adverse Reaction
Chulalongkorn University

Completed

Skin Testing and ELISPOT Assay in Patients With a History of Non-Immediate Reactions to Cephalosporins

Cephalosporin Allergy | Non-immediate Drug Reactions

Thailand
Zhejiang Cancer Hospital

Unknown

Exploratory Study on the S-1 + Paclitaxel Chemotherapy for Unresectable Gastric Cancer

Drug Safety | Surgically-Created Resection Cavity

China
Institute of Liver and Biliary Sciences, India

Terminated

Efficacy of N-acetylcysteine With or Without Steroids in Drug Induced Liver Injury

Drug Induced Liver Injury

India
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Yangxue Shengfa Capsule.

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Granule

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Pill.

Drug-Induced Liver Injury

China
Assiut University

Recruiting

Evaluation of Drug Overdose Poisoning Cases and Indications for ICU Admission

Drug Toxicity

Egypt
Xiangya Hospital of Central South University

Completed

Pharmacogenetics Study on the Effects of Anesthetic Drugs on Circulatory Function

Drug Reaction | Hemodynamic Rebound | Gene | Anesthetic

China
Chulalongkorn University
Mahidol University; Chiang Mai University; Phramongkutklao College of Medicine... and other collaborators

Unknown

Severe Cutaneous Adverse Reactions in Thailand (ThaiSCAR)

Drug Reaction With Eosinophilia and Systemic Symptoms | Toxic Epidermal Necrolysis | Acute Generalized Exanthematous Pustulosis | Steven-Johnson Syndrome | Generalized Bullous Fixed Drug Eruption

Thailand
Duke University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Drug-Induced Liver Injury (DILI) Network Retrospective (ILIAD)

Drug Induced Liver Injury

United States
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Runzao Zhiyang Capsule.

Drug-Induced Liver Injury

China
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Xianlin Gubao Capsule.

Drug-Induced Liver Injury

China
Drug Induced Liver Disease Study Group
Unimed Scientific Inc.

Completed

A Retrospective Study on Drug Induced Liver Injury in China (DILI-R)

Drug-Induced Liver Injury

China
University of North Carolina, Chapel Hill

Completed

Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury

Drug Induced Liver Injury

United States
Beijing 302 Hospital

Unknown

Surveillance for Early Liver Injuries Caused by Zhuanggu Guanjie Pill

Drug-Induced Liver Injury

China
China National Center for Cardiovascular Diseases

Recruiting

STrategies of Scheduled Drug-coated Balloons (DCB) Versus Conventional DES for the interveNTional Therapy of de Novo Lesions in Large Coronary vESSels (STENTLESS) Trial (STENTLESS)

De Novo Stenosis | Drug-coated Balloon | Drug-eluting Stent

China
Central Hospital, Nancy, France

Recruiting

Retrospective Study of Immediate Hypersensitivity (IHS) Reactions to Platinum Salts in the University Hospital of Nancy

Drug Allergy

France
Alexandria University

Completed

Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars

Local Anaesthetic Drug Adverse Reaction

Egypt
University of Edinburgh
NHS Lothian

Completed

Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients (ALISTER)

Tuberculosis | Drug-Induced Liver Injury | Anti-Tuberculous Drug Reaction

United Kingdom
MicroDose Therapeutx, Inc

Completed

A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of MDT-637 in Healthy Volunteers

Respiratory Syncytial Virus Infections | Drug Safety

United States
University Hospital, Geneva

Terminated

Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol (PUPICYP)

Drug Effect | Drug Intolerance | Cytochrome P450 CYP2D6 Enzyme Deficiency

Switzerland
University of Southern California

Enrolling by invitation

Cyclosporine vs Steroids in DRESS

DRESS Syndrome | Drug-Induced Hypersensitivity Syndrome

United States

Clinical Trials on Drug Safety ; Drug Specificity

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