Clinical Trials on Drug-Induced Hypersensitivity Syndrome in United Kingdom

Total 1335 results

Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
West Virginia University

Terminated

Eniluracil Hand Foot Syndrome

Breast Cancer | Colon Cancer

United States
University of North Carolina, Chapel Hill

Completed

Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury

Drug Induced Liver Injury

United States
Duke University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Drug-Induced Liver Injury (DILI) Network Retrospective (ILIAD)

Drug Induced Liver Injury

United States
Brigham and Women's Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease (MARINER)

Nasal Polyps | Aspirin-Sensitive Asthma With Nasal Polyps | Asthma, Aspirin-Induced | Aspirin-Exacerbated Respiratory Disease

United States
Brigham and Women's Hospital

Completed

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

Nasal Polyps | Aspirin-exacerbated Respiratory Disease | Aspirin-Sensitive Asthma With Nasal Polyps | Asthma, Aspirin-Induced

United States
NHS Greater Glasgow and Clyde

Recruiting

Biomarkers for Chemotherapy Associated Neurotoxicity (BioCAN)

Chemotherapy-Related Cognitive Impairment

United Kingdom
Egetis Therapeutics
University of Edinburgh; NHS Lothian

Completed

PP100-01 (Calmangafodipir) for Overdose of Paracetamol (POP)

Paracetamol Overdose

United Kingdom
Queen's University, Belfast

Active, not recruiting

Late Anthracycline Induced Cardiotoxicity- Childhood Cancer Survivors

Anthracycline Induced Cardiotoxicity

United Kingdom
NHS Greater Glasgow and Clyde
Pneumowave Ltd

Recruiting

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED)

Respiratory Insufficiency | Overdose of Opiate | Sedative Overdose | Sedative Toxicity

United Kingdom
University of Edinburgh

Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction (FCDMI)

Aortic Stenosis | Carcinoid Syndrome | Chemotherapy Induced Systolic Dysfunction

United Kingdom
Tabula Rasa HealthCare

Withdrawn

Implementation of a Pharmacist-led Pharmacogenomic Clinical Service

Elderly | Adverse Drug Event | Pharmacogenomics | Drug Drug Interaction

United States
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome

Carcinoid Syndrome

Germany, United Kingdom
Royal Sussex County Hospital

Unknown

Can we Help People With the Oral Allergy Syndrome Eat Fresh Fruit?

Oral Allergy Syndrome

United Kingdom
Columbia University

Withdrawn

Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

Liver Failure | Liver Failure, Acute | Fever | Prevention & Control | Drug Induced Liver Injury

United States
University of Aberdeen
NHS Grampian

Recruiting

Chemotherapy Induced Cognitive Impairment (CONCERT)

Breast Cancer

United Kingdom
Texas A&M University
InnovativeGx; Texas A&M Health Family Care Clinic; iC42 Clinical Research and... and other collaborators

Recruiting

The Texas Interprofessional Pharmacogenomics (IPGx)

Adverse Drug Reaction

United States
University of Pittsburgh
RAND

Completed

Enhancing the Detection and Management of Adverse Drug Events in Nursing Homes

Adverse Drug Events

United States
Indiana University
National Human Genome Research Institute (NHGRI)

Completed

A Prospective Trial to Assess Cost and Clinical Outcomes of a Clinical Pharmacogenomic Program (INGenious)

Adverse Drug Reaction

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
US Department of Veterans Affairs

Completed

Patient Profiling and Provider Feedback to Reduce Adverse Drug Events

Adverse Drug Events

United States
University of California, San Diego
National Institute of Mental Health (NIMH)

Completed

Movement Disorders Caused by Antipsychotic Drugs in Older Patients

Dyskinesia, Drug-Induced

United States
Richard Dart, MD, PhD
Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division

Recruiting

Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose

Liver Failure | Drug Overdose | Acetaminophen Overdose | Acetaminophen | Drug-induced Liver Injury | Acetaminophen Poisoning | Liver Toxicity

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
Intermountain Health Care, Inc.

Completed

Response to Medication Registry

Adverse Drug Events

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer

Breast Cancer | Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer | Endometrial Cancer | Drug/Agent Toxicity by Tissue/Organ

United States
University of California, Los Angeles

Recruiting

FAPI PET for Lung Fibrosis (FAPI ILD)

Pulmonary Fibrosis | Pneumoconiosis | Interstitial Lung Disease | Idiopathic Interstitial Pneumonias | Radiation Pneumonitis | Hypersensitivity Pneumonitis | Drug-Induced Pneumonitis

United States
Population Council

Completed

An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women

Antifungal Drug Adverse Reaction

United States
Queen Mary University of London
Royal Free Hospital NHS Foundation Trust

Active, not recruiting

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease (TRICAR)

Carcinoid Syndrome | Carcinoid Heart Disease | Tricuspid Regurgitation | Tricuspid Valve Disease

United Kingdom
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Active, not recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study (MOMs-CMA)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Drug Abuse in Pregnancy | Neonatal Opioid Withdrawal Syndrome

United States
Indiana University
Brigham and Women's Hospital

Completed

Improving Safety by Basic Computerizing Outpatient Prescribing

Adverse Drug Events

United States
VA Office of Research and Development

Completed

Implementation of Real-time ADE Surveillance and Decision Support (VA ADE)

Adverse Drug Events

United States
University of Massachusetts, Worcester
Agency for Healthcare Research and Quality (AHRQ); Qualidigm

Completed

Enhancing the Safety of Warfarin in Nursing Homes

Adverse Drug Events (ADEs)

United States
Eagle Pharmaceuticals, Inc.

Terminated

Efficacy and Safety Study of Ryanodex as Adjuvant Treatment in Subjects With Psychostimulant Drug-Induced Toxicity (PDIT)

Drug Toxicity Psychotropic Agents Psychostimulants

United States
Walter Reed National Military Medical Center
United States Department of Defense; General Services Administration (GSA)

Active, not recruiting

Reducing Concurrent Opioid-Benzodiazepine Prescriptions

Adverse Drug Effect of Opioids | Adverse Drug Effect of Benzodiazepines

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100

Drug Toxicity

United States
Oregon Health and Science University
Oregon State University; Oregon Department of Corrections; CODA Inc.; Bridgeway... and other collaborators

Completed

Reducing Overdose After Release From Incarceration (ROAR)

Overdose, Drug

United States
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
University of South Alabama
University of Alabama at Birmingham; University of Nevada, Las Vegas; Rutgers... and other collaborators

Recruiting

Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity

Drug Toxicity

United States
Joseph B. Ciolino, MD

Completed

Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis

Autoimmune Diseases | Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Ocular Cicatricial Pemphigoid | Stevens Johnson Syndrome | Chemical Injuries | Unspecified Complication of Corneal Transplant | Other Autoimmune Diseases

United States
Pharmaceutical Project Solutions, Inc.

Completed

Topical Anesthetic for Procedures Through the Nose

Drug Reaction to Analgesic Nos

United States
VA Office of Research and Development
Icahn School of Medicine at Mount Sinai; Weill Medical College of Cornell University and other collaborators

Completed

Regional Data Exchange to Improve Medication Safety

Drug Toxicity

United States
Massachusetts General Hospital

Terminated

Ultrasound Method to Measure Fibrosis of the Liver in Children

HBV | Chronic Liver Disease | HCV Coinfection | Non-Alcoholic Fatty Liver Disease | Drug-Induced Liver Injury

United States
The University of Texas Health Science Center,...
Blue Cross Blue Shield

Completed

Reducing Costs by Deprescribing Medications

Deprescribing | Polypharmacy | Adverse Drug Reaction

United States
Boston Medical Center
Boston University; National Institute on Drug Abuse (NIDA); RTI International

Completed

Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use (ASPIRE)

Drug Abuse | Drug Usage | Drug Dependence

United States
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Blue Cross Blue Shield; Agency for Healthcare...

Completed

Preventing Adverse Drug Events With PatientSite

Adverse Drug Event

United States
Michigan State University
University of Wisconsin, Madison

Completed

Over-the-counter (OTC) Labels for Older Adults

Adverse Drug Event

United States
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Aminotransferase Trends During Prolonged Acetaminophen Dosing

Healthy | Drug Toxicity

United States
Johns Hopkins Bloomberg School of Public Health
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Social Network Overdose Prevention and Education Intervention

Drug Overdose

United States

Clinical Trials on Drug-Induced Hypersensitivity Syndrome in United Kingdom

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