Clinical Trials on Drug-resistant Tuberculosis in Germany

Total 313 results

Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of Centralised TB Assay Solutions

Tuberculosis | Drug-resistant Tuberculosis

Georgia, Germany, India, Moldova, Republic of, South Africa
Research Center Borstel

Completed

Biomarkers for Therapy Response in Drug-resistant Tuberculosis

Tuberculosis, Multidrug-resistant

Germany
University Hospital Marburg

Recruiting

IF-MCT 16:8: Investigating the Influence of Intermittent Fasting With and Without MCTs in Patients With Drug-resistant Epilepsy (IF-MCT16:8)

Epilepsy | Intermittent Fasting

Germany
Research Center Borstel
Ludwig-Maximilians - University of Munich

Terminated

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Bacterial Infections | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Mycobacterial Infection

Germany, Moldova, Republic of, Romania, Ukraine
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Technical University of Munich

Recruiting

Helicobacter Pylori Local Prevalence and Antibiotic Resistance (HelicoPTER)

Gastric Cancer | Microbial Colonization | Helicobacter Pylori Infection | Antibiotic Resistant Infection | Helicobacter Pylori Gastritis | Drug Resistant Bacterial Infection

Germany
Zogenix, Inc.
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.

Terminated

European Non-interventional Study on Refractory Epilepsy With Developmental Delay

Refractory Epilepsy | Development Delay

Germany, Spain, France, Italy
Swedish Orphan Biovitrum
Parexel

Completed

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Drug Drug Interaction

Germany
Cyberonics, Inc.

Completed

PuLsE 2-Observational Long-Term Effectiveness Follow-Up Study of PuLsE 1 (PuLsE 2)

Epilepsy

France, Belgium, Italy, United Kingdom, Germany, Canada, Netherlands
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
University Heart Center Freiburg - Bad Krozingen

Unknown

Effect of Clopidogrel Loading and Risk of PCI (EXCELSIOR)

Coronary Artery Disease | Drug Resistance

Germany
University Heart Center Freiburg - Bad Krozingen

Completed

Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition

Coronary Artery Disease | Drug Resistance

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
UCB Biopharma SRL

Terminated

An Open-label Extension Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy

Highly Drug-resistant Focal Epilepsy

Belgium, Bulgaria, Germany, Hungary, Netherlands, Spain
Marinus Pharmaceuticals

Completed

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Drug Resistant Partial Onset Seizure

United States, Australia, Russian Federation, Bulgaria, Germany, Poland
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
Duke University
Christian Doppler University Hospital

Enrolling by invitation

5-SENSE Score Validation Study

Epilepsy Intractable

United States, Spain, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Switzerland
UCB Biopharma S.P.R.L.
PRA Health Sciences

Completed

A Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy

Highly Drug-resistant Focal Epilepsy

Belgium, Bulgaria, Germany, Hungary, Netherlands, Spain
Gerd Mikus

Completed

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Drug Interactions

Germany
Bayer

Completed

Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin

Drug Interactions

Germany
Charite University, Berlin, Germany

Completed

Questionnaire of the Section Perioperative Intensive Care of the European Society of Intensive Care Medicine (ESICM) on Standardized Drug Labelling

Drug Labelling

Germany
Maastricht University
European Commission

Completed

Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers (REPO-STROKE1)

Safety Issues | Drug Drug Interaction

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
University Medical Center Goettingen

Completed

Open Label Pharmacokinetic-Pharmacogenetic Study on Polymorphisms in the Organic Cation Transporter OCT1 (PG-OCT)

Drug Metabolism | Membrane Transport

Germany
LEO Pharma

Completed

Open-label, Single Center, Non-randomized, Fixed Sequence Phase 1 Drug-drug Interaction Study With LEO 32731 and Midazolam

Drug Interaction Potentiation

Germany
Technical University of Munich

Completed

Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers

Anesthesia | Drug Effects

Germany
Bayer

Completed

Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women

Drug Interactions

Germany
Institut fuer anwendungsorientierte Forschung und...

Completed

Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

Membrane Transport | Drug Biotransformation

Germany
Max Zeller Soehne AG

Unknown

Drug Cocktail Interaction Study of St. John's Wort Dry Extract Ze 117

Drug Interaction Study

Germany
Central Institute of Mental Health, Mannheim
Charite University, Berlin, Germany; German Federal Ministry of Education and... and other collaborators

Active, not recruiting

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression (EPIsoDE)

Treatment-resistant Depression

Germany
RWTH Aachen University
Ärztliche Zentrum für Qualität in der Medizin; Universitätsklinikum Bonn -...

Completed

Medication Reconciliation in Comparison to an Extensive Medication Safety Check

Elderly | Adverse Drug Event

Germany
Dr. Frank Behrens
Bionorica SE

Active, not recruiting

Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo (SILVER)

Drug-induced Liver Injury

Germany
Ludwig-Maximilians - University of Munich

Completed

Transcranial Direct Current Stimulation (tDCS) in Treatment-resistant Depression

Therapy Resistant Major Depression

Germany
Matthias Schwab

Completed

Open Label Study for the Functional Characterization of Drug Metabolism and Transport (IKP243)

Genotype-related Drug Metabolism

Germany
Technical University of Munich

Completed

Detection of Consciousness by EEG and Auditory Evoked Potentials

Anesthesia | Electroencephalography/ Drug Effect

Germany
Aesculap AG

Completed

DS Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy) (DOSTILCU)

Kidney Cancer | Nephrolithiasis | Prostate Cancer | Nephritis | Kidney Injury | Hydronephrosis | Congenital Abnormality of Kidney | Kidney Tuberculosis

Germany
Bayer

Completed

Pharmacy Based Pharmacoepidemiological Observational Study With Aspirin Protect 100 mg

Aspirin | Drug Safety | Effects, Longterm

Germany
Klemens Budde
Novartis Pharmaceuticals

Completed

Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS

Immunosuppression | Transplantation | Drug Interaction

Germany
University Hospital Freiburg
Boston Scientific Corporation

Recruiting

Efficacy Study of Deep Brain Stimulation in Patients With Treatment Resistant Major Depression (FORESEE III)

Treatment-resistant Depression

Germany, France
Heinrich-Heine University, Duesseldorf

Terminated

The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients (BRIMOCAN)

Hand-foot Syndrome

Germany
University Hospital Freiburg

Withdrawn

Aripiprazole Augmentation Therapy in Treatment-resistant Depression

Therapy-resistant Depression

Germany
University Hospital Freiburg

Withdrawn

Olanzapine Augmentation Therapy in Treatment-resistant Depression: a Double-blind Placebo-controlled Trial

Therapy-resistant Depression

Germany
Charite University, Berlin, Germany
Hannover Medical School; Ludwig-Maximilians - University of Munich; University...

Completed

Berlin Deep Brain Stimulation Depression Study (BDDS)

Treatment Resistant Depression

Germany

Clinical Trials on Drug-resistant Tuberculosis in Germany

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