Clinical Trials on ERBB2 Gene Mutation

Total 1898 results

Boninger, Michael, MD
National Institute of Neurological Disorders and Stroke (NINDS); Ripple Therapeutics...

Recruiting

Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation (MIRA)

Amputation | Amputation; Traumatic, Hand

United States
Shirley Ryan AbilityLab

Recruiting

Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait

Amputation | Amputation, Traumatic | Amputation; Traumatic, Limb | Amputation of Knee

United States
Fondazione Don Carlo Gnocchi Onlus

Completed

Multicentre Interventional Pilot Study on the Evaluation of the Functionality, Safety and Reliability of a New Robotic Prosthesis for the Lower Limb at the Transfemoral Level (MOTU-ATP)

Amputation | Amputation; Traumatic, Leg, Lower

Italy
Fondazione Don Carlo Gnocchi Onlus

Completed

Interventional Study on the Evaluation of Functionality, Safety of a Robotic Prosthesis for Transtibial Amputations

Amputation | Amputation; Traumatic, Leg, Lower

Italy
Brigham and Women's Hospital

Recruiting

Vascularized Composite Allotransplantation for Multiple Extremity Amputations

Limb Amputation | Extremity Amputation

United States
Henry M. Jackson Foundation for the Advancement...
University of Miami; Walter Reed National Military Medical Center; Uniformed... and other collaborators

Unknown

Mobile Device Outcomes-based Rehabilitation Program (MDORP)

Transtibial Amputation | Transfemoral Amputation

United States
Columbia University
American Cancer Society, Inc.

Completed

Decision Support for BRCA Testing in Ethnically Diverse Women

Breast Cancer | Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation

United States
The University of Hong Kong

Completed

Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITD

AML | FLT3-ITD Mutation

Hong Kong
Pfizer

Completed

Transthyretin Amyloidosis Outcome Survey (THAOS) (THAOS)

Transthyretin Amyloidosis | Transthyretin Gene Mutations

United States, France, Spain, Taiwan, Israel, Korea, Republic of, Denmark, Canada, Netherlands, Japan, Sweden, Brazil, Mexico, Argentina, Portugal, Belgium, Bulgaria, Cyprus, Germany, Italy, Malaysia, Romania, Saudi Arabia, Turkey, United...
Liberating Technologies, Inc.
Össur Ehf

Completed

Dexterous Partial Hand Prosthesis Outcomes

Amputation | Prosthesis User | Amputation; Traumatic, Hand | Upper Limb Amputation at the Hand | Limb; Absence, Congenital, Upper

United States
University of Michigan

Active, not recruiting

A Comparative Assessment of Transfemoral Prosthetic Sockets

Amputation | Amputation; Traumatic, Leg, Lower

United States
Shirley Ryan AbilityLab
United States Department of Defense

Completed

Comparison of Pattern Recognition Control and Direct Control in TMR

Amputation | Amputation; Traumatic, Arm, Upper

United States
BeBetter Med Inc
Xiangya Hospital of Central South University

Recruiting

Study of BEBT-607 Tablets in The Treatment of Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

Advanced or Metastatic Solid Tumor | KRAS G12C Mutation

China
Boehringer Ingelheim

Completed

A Study to Find a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in Patients With Advanced Cancer and a Certain Mutation (Kirsten Rat Sarcoma Viral Oncogene Homologue [KRAS])

Solid Tumors, KRAS Mutation

Japan
University Health Network, Toronto

Active, not recruiting

Integrative Sequencing In Germline and Hereditary Tumours (INSIGHT)

Mutation | Hereditary Cancer Syndrome | High-Risk | Germline Mutation

Canada
Chang Gung Memorial Hospital
Intuitive Surgical

Active, not recruiting

Pilot Study of Single-port Robot-assisted Nipple-sparing Mastectomy

Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Nipple-sparing Mastectomy | Prophylactic Mastectomy

Taiwan
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

An Open Label, Multi-center, Phase I Clinical Study to Evaluate the Safety, Effectiveness and Pharmacokinetic Characteristics of SIM1803-1A in Patients With Locally Advanced/Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion Mutations.

Advanced or Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion

China
St Vincent's Hospital, Sydney

Terminated

Activity of Seviteronel in Patients With Androgen Receptor (AR)-Positive Glioblastoma (START)

Solid Tumor | Androgen Receptor Gene Overexpression

Australia
University of Michigan

Completed

No Power Bionic Lower Extremity Prosthesis

Amputation | Amputation, Traumatic | Amputation; Traumatic, Leg, Lower

United States
Point Designs
University of Colorado, Denver

Completed

Validation of Point Partial User Needs With Partial Finger Amputees

Amputation; Traumatic, Hand

United States
Centre Hospitalier Universitaire de Nīmes

Completed

The Injury and Its Consequences in the Sports Lower Limb Amputee (PREV'AMP SPORT)

Traumatic Amputation | Leg Lower Amputation

France
Martin Berli
Bern University of Applied Sciences

Completed

Sensor Glove and Non-Invasive Vibrotactile Feedback Insole to Improve Hand Prostheses Functions and Embodiment (FeetBack)

Amputation; Traumatic, Hand

Switzerland
University of Nevada, Las Vegas

Not yet recruiting

Prosthetic Performance Enhancement Trial (PROSPER)

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury) | Amputation | Lower Limb Amputation Knee | Lower Limb Amputation at Ankle (Injury) | Lower Limb Amputation at Hip (Injury)

United States
Marmara University

Completed

Turkish Validation of Prosthesis Donning and Doffing Questionnaire

Amputation; Traumatic, Leg, Lower

Turkey
VA Office of Research and Development

Completed

Home Study of an Advanced Upper Limb Prosthesis

Traumatic Amputation of Arm

United States
US Department of Veterans Affairs
Brown University; Lifespan

Completed

Interface Kinematics of Transhumeral Prosthetic Sockets Using XROMM

Traumatic Amputation of Arm

United States
Helse Møre og Romsdal HF

Not yet recruiting

ATTR Cardiac Amyloidosis in a Selected Population

Carpal Tunnel Syndrome | Cardiac Amyloidosis | ATTR Amyloidosis Wild Type | ATTR Gene Mutation
Ascentage Pharma Group Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of APG-115 in Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Melanoma | P53 Mutation | Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | Unresectable or Metastatic Melanoma or Advanced Solid Tumors | MDM2 Gene Mutation

United States, Australia
Southern Illinois University
Memorial Medical Center; Memorial Medical Center Foundation

Completed

Vascularized Composite Allotransplantation of the Hand and Upper Extremity (Hand Transplant)

Traumatic Amputation of Arm | Traumatic Amputation of Hand

United States
The University of Texas Health Science Center at...

Withdrawn

Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients

Ovarian Cancer | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation
Orthopus
Handicap International

Recruiting

Study of the Social and Professional Reintegration Improvements Using a Set of Solutions for Upper Limb Amputation

Wounds and Injuries | Amputation; Traumatic, Arm, Upper | Amputation; Traumatic, Hand, at Wrist Level | Amputation; Traumatic, Arm: Forearm

Nepal
Coapt, LLC
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pattern Recognition Prosthetic Control (Simultaneous)

Prosthesis User | Congenital Amputation of Upper Limb | Amputation; Traumatic, Limb

United States
Novartis Pharmaceuticals

Completed

Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms

NALP3 Mutation

United Kingdom, France, Germany, India, Spain
Sint Maartenskliniek

Completed

Effect of Sports-oriented Rehabilitation on Mobility and Daily Activity in People With a Lower-limb Amputation

Amputation | Lower Limb Amputation

Netherlands
Liberating Technologies, Inc.

Withdrawn

Evaluation of Dexterous Terminal Device

Amputation | Prosthesis User | Amputation; Traumatic, Hand | Amputation, Traumatic | Upper Limb Amputation at the Hand | Upper Limb Amputation Below Elbow (Injury) | Limb; Absence, Congenital, Upper
Black Diamond Therapeutics, Inc.

Recruiting

A Study of BDTX-4933 in Patients With KRAS, BRAF and Select RAS/MAPK Mutation-Positive Cancers

Melanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditions

United States
HaoxuanZhang

Recruiting

Correlation Between Microbial Infection and Lumbar Degenerative Disease Based on High-throughput Gene Sequencing

Gene Product Sequence Variation | Lumbar Degenerative Diseases

China
Arog Pharmaceuticals, Inc.
Centre Leon Berard; Fox Chase Cancer Center

Unknown

Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST

GIST With D842V Mutated PDGFRA Gene

United States, France, Spain, Italy, Germany, Norway, Poland
Betta Pharmaceuticals Co., Ltd.

Unknown

X-396 Capsule in Advanced NSCLC Patients With ROS1 Gene Rearrangement

Lung Cancer | ROS1 Gene Rearrangement

China
VA Eastern Colorado Health Care System

Completed

Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development

Traumatic Amputation of Lower Extremity

United States
Alicia Koontz

Completed

Functional Electrical Stimulation Use in Trans-tibial Amputations

Traumatic Amputation of Lower Extremity

United States
Miami VA Healthcare System

Completed

A Comparison of External Mechanical Work Between Different Prosthetic Feet (SEW)

Traumatic Amputation of Lower Extremity

United States
VA Office of Research and Development

Recruiting

Improving Socket Fit in Female and Male Veterans With Transtibial and Transfemoral Amputation (SocketFit)

Transtibial Amputation | Transfemoral Amputation

United States
University of Colorado, Denver
United States Department of Defense

Recruiting

Transfemoral Osseointegrated Prosthesis Limb-Load Symmetry Training (TOPLOAD)

Amputation | Transfemoral Amputation | Osseointegration

United States
Shirley Ryan AbilityLab

Recruiting

Low Cost Socket for Lower Limb Amputees

Amputation | Amputation, Traumatic | Amputation; Traumatic, Limb

United States
VA Office of Research and Development

Completed

Longitudinal Study of Weight Change Following Lower Limb Amputation

Amputation Wound | Traumatic Amputation of Toe | Dysvascular Amputation of Lower Limb

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Functional Outcomes of Single Digit Replantation Versus Revision Amputation

Amputation; Traumatic, Hand

Canada
Centre hospitalier de l'Université de Montréal...

Recruiting

Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization

Amputation; Traumatic, Hand

Canada
Point Designs
University of Colorado, Denver; Arm Dynamics

Completed

To Assess the Utility of the Point Digit in a Clinical Take-home Study

Amputation; Traumatic, Hand

United States
Point Designs
University of Colorado, Denver; Arm Dynamics

Completed

To Assess the Utility of the Point Partial in a Clinical Take-home Study of Partial Hand Amputees

Amputation; Traumatic, Hand

United States

Clinical Trials on ERBB2 Gene Mutation

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