Clinical Trials on Early-Onset Alzheimer Disease in Belgium

Total 134 results

Universitaire Ziekenhuizen KU Leuven

Unknown

New Proteins in Body Fluids as Potential Biomarker for Alzheimer's Disease: a Pilot Study

Alzheimer Disease, Late Onset

Belgium
Bristol-Myers Squibb

Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease (TargetTau-1)

Alzheimer Disease, Early Onset

United States, Australia, Belgium, Canada, Denmark, France, Japan, Korea, Republic of, Netherlands, Poland, Singapore, Spain, Sweden, United Kingdom
Universitair Ziekenhuis Brussel

Completed

Engagement 2.0 Forms of Consent for Data (re-)Use (ENGAGE)

Mild Cognitive Impairment | Alzheimer Disease, Early Onset

Belgium
KU Leuven
Odisee University college for applied sciences

Not yet recruiting

Anxiety, Stress and Sleep Problems in People With Early Onset Dementia (Young-D)

Stress | Insomnia | Sleep | Anxiety | Distress, Emotional | Sleep Problem | Early Onset Dementia | Young Onset Dementia

Belgium
Novo Nordisk A/S

Active, not recruiting

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Early Alzheimer´s Disease

Canada, United States, Taiwan, Netherlands, United Kingdom, Spain, Austria, Korea, Republic of, Portugal, Italy, Australia, Argentina, Hungary, Germany, Brazil, China, Poland, Denmark, Czechia, Ireland, Japan, South Africa, Romania, S... and more
Novo Nordisk A/S

Active, not recruiting

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)

Early Alzheimer's Disease

Canada, United States, Spain, Netherlands, United Kingdom, Austria, Korea, Republic of, Portugal, Italy, Australia, Argentina, Hungary, Germany, Brazil, Poland, Denmark, Czechia, Ireland, Norway, Japan, Romania, South Africa, Sweden, ... and more
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Prevalence of Epilepsy and Sleep Wake Disorders in Alzheimer Disease (PESAD)

Epilepsy | Sleep Wake Disorders | Alzheimer Disease | Alzheimer Dementia

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Optical Coherence Tomography in Cerebral Amyloidosis

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Dementia Alzheimers | Dementia, Lewy Body

Belgium
Murielle Surquin

Completed

Reported Time Between Onset and Diagnosis of Alzheimer's Disease: Correlation With Objective Parameters

Alzheimer Disease

Belgium
University Hospital, Ghent

Active, not recruiting

Hormone Replacement Trial Against ALzheimers' Disease (HARALD)

Alzheimer Disease | Postmenopausal Symptoms

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

The Detection of Early Dementia With the Digital Game Memory

Alzheimer's Disease

Belgium
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

Alzheimer Disease

Belgium
Universitair Ziekenhuis Brussel

Recruiting

Melatonin in Alzheimer's Disease: Effect on Disease Progression and Epileptiform Activity. (MADE)

Alzheimer Disease

Belgium
Novartis Pharmaceuticals
National Institute on Aging (NIA); Amgen; Banner Alzheimer's Institute

Terminated

A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS1)

Alzheimers Disease

United States, Belgium, United Kingdom, Germany, Australia, Canada, Spain, Finland, Switzerland, Netherlands
Janssen Research & Development, LLC

Completed

Characterization of T-Cell Response in Participants Previously Treated With JNJ-54861911 (Atabecestat)

Alzheimer Disease

France, Belgium, Germany, Spain, Sweden
Brugmann University Hospital

Completed

Mirtazapine in Alzheimer-associated Weight Loss

Dementia | Weight Loss | Alzheimer's Disease | Mixed Dementia

Belgium
Novartis Pharmaceuticals
Amgen; Banner Alzheimer's Institute

Terminated

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS2)

Alzheimers Disease

Spain, United States, Belgium, Italy, Germany, Australia, Israel, Taiwan, Japan, Canada, Korea, Republic of, United Kingdom, France, China, Argentina, Finland, Singapore, Portugal, Chile, Mexico, Switzerland, Netherlands, Iceland, Puerto... and more
University Hospital, Ghent

Recruiting

Spatial Navigation for the Early Detection of Alzheimer's Disease. (ALLO-task)

Alzheimer Disease | Healthy Aging | Mild Cognitive Impairment

Belgium
Janssen Research & Development, LLC

Completed

A Study to Measure CSF Proteins in Elderly Healthy Volunteers and Volunteers With Mild Cognitive Impairment or Alzheimer's Disease

Healthy | Alzheimer Disease

Netherlands, Belgium
Janssen Research & Development, LLC

Completed

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease

Alzheimer Disease

Belgium, Spain, Netherlands, Germany
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Belgium, Finland, Netherlands, Serbia, Sweden
Universitair Ziekenhuis Brussel

Recruiting

Epilepsy in Alzheimer's Disease: Effect on Disease Progression (EADP)

Alzheimer Disease | Mild Cognitive Impairment

Belgium
ReST Therapeutics

Withdrawn

First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM)

Brain Diseases | PTSD | Alzheimer Disease | Major Depressive Disorder | Treatment Resistant Depression | Neuro-Degenerative Disease

Belgium
Raman Health Technologies, S.L.

Completed

Multi-parameter Diagnostic Blood Test for the Diagnosis of Alzheimer's Disease (RH-VAL)

Alzheimer Disease

Spain, Belgium, France
University of Liege

Completed

Efficacy of Microcurrent Therapy After Eccentric Exercise

Delayed Onset Muscle Soreness

Belgium
Universitaire Ziekenhuizen KU Leuven

Recruiting

Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease (RetAD)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Alzheimer Dementia

Belgium
Cliniques universitaires Saint-Luc- Université...

Completed

Observational Trial on the Impact of Hypnose Used as a Sedation in Oncology Surgery in Breast Cancer

Early Stage Breast Carcinoma

Belgium
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease

Alzheimer Disease

Spain, Netherlands, Belgium, Sweden
Janssen Research & Development, LLC

Terminated

An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum

Alzheimer Disease

France, Spain, Netherlands, Belgium, Germany, Sweden
Baxalta now part of Shire

Terminated

Phase 3 IGIV, 10% in Alzheimer´s Disease

Alzheimer´s Disease

United States, Poland, United Kingdom, Belgium, Spain, Japan, Canada, Australia
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Apollo Therapeutics Ltd

Terminated

A Study to Evaluate Camoteskimab in Participants With Still's Disease

Adult Onset Still's Disease

United States, Belgium, Poland, Ukraine
Janssen Research & Development, LLC

Completed

A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease

Alzheimer's Disease

France, Spain, Netherlands, Belgium, Germany, Sweden
University Hospital, Ghent
GC Europe

Completed

A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 1

Early Caries Lesions

Belgium
University Hospital, Ghent
GC Europe

Completed

A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2

Early Caries Lesions

Belgium
Vivoryon Therapeutics N.V.
Amsterdam UMC, location VUmc; Julius Clinical

Completed

Safety and Tolerability of PQ912 in Subjects With Early Alzheimer's Disease (SAPHIR)

Alzheimer's Disease

Spain, Finland, Germany, Netherlands, Belgium, France, Sweden
Noscira SA
ICON Clinical Research

Completed

Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients (ARGO)

Alzheimer's Disease

Belgium, Finland, France, Germany, Spain, United Kingdom
Universitair Ziekenhuis Brussel
eTheRNA immunotherapies

Recruiting

Intratumoral TriMix Injections in Early Breast Cancer Patients (TMBA)

Breast Cancer Female | Early-stage Breast Cancer

Belgium
Novartis Pharmaceuticals

Completed

Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age

Alzheimer's Disease

Netherlands, United States, Belgium, Germany, United Kingdom
Universitaire Ziekenhuizen KU Leuven

Recruiting

In Vivo PET of Synaptic Density in Cognitive Disorders

Alzheimer Disease | Frontotemporal Degeneration | Psychiatric Disorder | Dementia With Lewy Bodies

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Randomized Trial Comparing Laparoscopic-assisted Rectosigmoid Resection Versus Laparoscopic Rectosigmoid Resection With Transrectal Specimen Retrieval (LATA)

Symptomatic Recurrent Diverticular Disease | Benign Adenomatous Sigmoidal Polyp, Requiring Surgery | Early Non-transmural Sigmoidtumor

Belgium
University Hospital, Antwerp
Universiteit Antwerpen

Unknown

Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects (GECkO)

Alzheimer Disease | Mild Cognitive Impairment | Hearing Loss, Sensorineural | Bilateral Vestibulopathy

Belgium
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
University of Edinburgh
Innovative Medicines Initiative

Terminated

European Prevention of Alzheimer's Dementia (EPAD) Longitudinal Cohort Study (LCS) (EPAD-LCS)

Alzheimer's Dementia

United Kingdom, Belgium, France, Greece, Italy, Netherlands, Spain, Sweden, Switzerland
Hoffmann-La Roche

Terminated

A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

Alzheimer Disease

Belgium, United States, Poland, Spain, Germany, Italy, France, United Kingdom
Novartis Pharmaceuticals

Completed

Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients

Alzheimer's Disease

Belgium, Switzerland, Spain, United States, Italy, Sweden, Canada, Germany, Norway, Netherlands
Jules Bordet Institute
KU Leuven; University of Milan

Not yet recruiting

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt) (KePreSt)

Early-stage Breast Cancer | Estrogen-receptor-positive Breast Cancer

Belgium
Jules Bordet Institute

Completed

PET Evaluation of Response After 1 Course of Chemotherapy as Predictor of Treatment Outcome. (earlyPETmCRC)

Colorectal Cancer Metastatic | Early Response Evaluation | Fdg-PET

Belgium
AstraZeneca
Eli Lilly and Company

Terminated

An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease (AMARANTH)

Alzheimer´s Disease

United States, Spain, Belgium, Australia, Hungary, Korea, Republic of, Canada, Germany, Japan, Romania, France, Poland, United Kingdom, Puerto Rico, Italy
University Hospital, Ghent

Completed

A Protocol Based Treatment for Early and Severe Systemic Sclerosis With (Anti-CD20), Rituximab

Early and Severe Systemic Sclerosis

Belgium

Clinical Trials on Early-Onset Alzheimer Disease in Belgium

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