- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03408041
Reported Time Between Onset and Diagnosis of Alzheimer's Disease: Correlation With Objective Parameters
The early diagnosis of Alzheimer's disease is essential to enable patients to have access to the available treatments. However, there is a delay between the diagnosis and the onset of symptoms, which can range from 1 year to more than 5 years. In clinical practice, the hippocampal volume, measured by the Scheltens index, is currently used as a marker of the progression of the disease.
The purpose of this study is to determine whether the patient's sex, age and ethnicity can influence the delay in the expression of cognitive troubles reported by the family at the first medical consultation, as well as to determine if there is a correlation between the delay reported by the family and the Scheltens index.
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
-
Brussels, Belgium
- CHU Brugmann
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- ADULT
- OLDER_ADULT
- CHILD
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013. Diagnose according to the Dubois criteria
Exclusion Criteria:
None
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Alzheimer Disease
Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013.
Diagnose according to the Dubois criteria
|
Medical file data extraction
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Age
Time Frame: Between 01-01-2010 and 31-01-2013
|
Age
|
Between 01-01-2010 and 31-01-2013
|
Sex
Time Frame: Between 01-01-2010 and 31-01-2013
|
Sex
|
Between 01-01-2010 and 31-01-2013
|
Ethnic origin
Time Frame: Between 01-01-2010 and 31-01-2013
|
Ethnic origin
|
Between 01-01-2010 and 31-01-2013
|
Symptoms-diagnose time interval
Time Frame: Between 01-01-2010 and 31-01-2013
|
Interval of time between the apparition of the first symptoms, as reported by the family, and the diagnose.
|
Between 01-01-2010 and 31-01-2013
|
Scheltens scale
Time Frame: Between 01-01-2010 and 31-01-2013
|
Evaluation of the hippocampal atrophy by means of magnetic resonance imaging.
Scale from 0 (normal) to 4.
|
Between 01-01-2010 and 31-01-2013
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Florence Benoit, MD, CHU Brugmann
Study record dates
Study Major Dates
Study Start (ACTUAL)
Primary Completion (ACTUAL)
Study Completion (ACTUAL)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ACTUAL)
Study Record Updates
Last Update Posted (ACTUAL)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- CHUB-parameters Alzheimer
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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