Clinical Trials on Elderly Adults

Total 4846 results

CytomX Therapeutics

Completed

PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL

Head and Neck Cancer | Esophageal Cancer | Non Small Cell Lung Cancer | Diffuse Large B Cell Lymphoma | Solid Tumor, Adult

United States, Spain, Korea, Republic of, United Kingdom
St. Luke's Health System, Boise, Idaho
Patient-Centered Outcomes Research Institute; University of Pennsylvania; Columbia... and other collaborators

Active, not recruiting

Suicide Prevention Among Recipients of Care (SPARC)

Adolescent | Depressive Disorder | Depression | Suicidal Ideation | Suicide, Attempted | Suicide | Mental Health | Loneliness | Social Support | Mental Disorder | Outpatients | Ambulatory Care | Continuity of Patient Care | Adult | Secondary Prevention | Emergency Service, Hospital | Mental Health Services | Patient Care Planning and other conditions

United States
University Hospital Tuebingen

Completed

Iloprost in Acute Respiratory Distress Syndrome (ThIlo)

Respiratory Distress Syndrome, Adult

Germany
Hospital Universitari de Bellvitge

Completed

Cost-effectiveness Study of a Lifestyle Change Program for the Treatment of OSA and Obesity: Hospital-Primary Care. (SPP-1)

Obesity | Weight Loss | Obstructive Sleep Apnea of Adult | Lifestyle

Spain
Academisch Medisch Centrum - Universiteit van Amsterdam...
Hospital Israelita Albert Einstein; Mahidol Oxford Tropical Medicine Research...

Completed

Practice of Ventilation in Middle-Income Countries (PRoVENT-iMIC)

Respiratory Distress Syndrome, Adult | Acute Respiratory Failure | Mechanical Ventilation

Thailand, India, Bangladesh, Vietnam, Iran, Islamic Republic of, Malaysia, Pakistan, Maldives, Nepal, Sri Lanka
Milton S. Hershey Medical Center

Terminated

Weaning From Mechanical Ventilation Using Permissive Hypercarbia

Respiratory Distress Syndrome, Adult | Respiration, Artificial

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Anemia in Patients With Solid Tumors

Lymphoma | Leukemia | Anemia | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) (EDEN)

Respiratory Distress Syndrome, Adult

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) (EDEN-Omega)

Respiratory Distress Syndrome, Adult

United States
National Cancer Institute (NCI)

Completed

Weekly Doses of Cilengitide and Paclitaxel in Treating Patients With Advanced Solid Tumors That Cannot Be Removed by Surgery

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

17-AAG in Treating Patients With Relapsed or Refractory Anaplastic Large Cell Lymphoma, Mantle Cell Lymphoma, or Hodgkin's Lymphoma

Recurrent Mantle Cell Lymphoma | Anaplastic Large Cell Lymphoma | Recurrent Adult Hodgkin Lymphoma

United States
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome

Respiratory Distress Syndrome, Adult

United States
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
NMC Specialty Hospital

Completed

Utility of Defining ARDS and Past and Current Definitions of ARDS (Delphi_ARDS)

Respiratory Failure | Respiratory Distress Syndrome, Adult | Hypoxemic Respiratory Failure | Phenotypic Abnormality | Delphi Study

United Arab Emirates
Duke University
National Cancer Institute (NCI)

Active, not recruiting

Symptom Management for YA Cancer Survivors

Melanoma | Pain | Cancer | Breast Cancer | Fatigue | Psychological Distress | Germ Cell Tumor | Young Adult | Hematologic Cancer | Endocrine Cancer

United States
Michael A. Matthay
The University of Texas Health Science Center, Houston; United States Department... and other collaborators

Completed

Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (STAT)

Respiratory Distress Syndrome, Adult

United States
Autolus Limited

Enrolling by invitation

Long-term Follow-up of Patients Treated With Autologous T Cells Genetically Modified

Multiple Myeloma | DLBCL | T Cell Lymphoma | Patients Followed for up to 15 Years Following Their First Dose of AUTO CAR T Cell Therapy | ALL, Adult and Pediatric

United Kingdom
M.D. Anderson Cancer Center
Katz Foundation

Completed

Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies

Adult Respiratory Distress Syndrome | Blood And Marrow Transplantation

United States
Faron Pharmaceuticals Ltd
Seventh Framework Programme

Terminated

Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS) (INTEREST)

Respiratory Distress Syndrome, Adult

Spain, United Kingdom, France, Italy, Finland, Czechia, Belgium, Germany
Hospital El Cruce

Completed

The Role of Morphological Phenotype in ARDS (MPARDS)

Respiratory Distress Syndrome, Adult

Argentina
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases

Pain | Kidney Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Melanoma (Skin)

United States
Technische Universität Dresden
Medical University of Vienna; University Hospital, Montpellier; University of... and other collaborators

Terminated

Variable Pressure Support Trial (ViPS)

Acute Lung Injury | Adult Respiratory Distress Syndrome | at Least 24 h of Controlled Mechanical Ventilation

Germany
University of Washington
National Cancer Institute (NCI)

Completed

Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm

Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Myelomonocytic Leukemia-2

United States
National Cancer Institute (NCI)

Completed

Veliparib and Radiation Therapy in Treating Patients With Advanced Solid Malignancies With Peritoneal Carcinomatosis, Epithelial Ovarian, Fallopian, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Peritoneal Carcinomatosis | Adult Solid Neoplasm

United States, Canada
Karolinska University Hospital
Karolinska Institutet

Unknown

Treatment of Severe Acute Respiratory Distress Syndrome With Allogeneic Bone Marrow-derived Mesenchymal Stromal Cells

Acute Respiratory Distress Syndrome, Adult

Sweden
St. Bartholomew's Hospital

Unknown

Epoetin Alfa or Epoetin Beta With or Without Iron Infusion in Treating Anemia in Patients With Cancer

Lymphoma | Leukemia | Anemia | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Completed

Flavopiridol Plus Cisplatin or Carboplatin in Treating Patients With Advanced Solid Tumors

Breast Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

United States
Extremity Medical

Recruiting

The KinematX Midcarpal Total Wrist Arthroplasty Registry

Osteoarthritis | Inflammatory Arthritis | Carpal Tunnel Syndrome (CTS) | Post Traumatic Arthritis | Scapholunate Advanced Collapse (SLAC) | Scapholunate Crystalline Advanced Collapse (SCAC) | Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC) | Kienbock's Disease of Adults | Radial Malunion | Ulnar Translocation and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Agatolimod Sodium, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent or Refractory Non-Hodgkin Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Recurrent... and other conditions

United States
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
University of California, San Diego

Not yet recruiting

Obstructive Sleep Apnea Treatment in Serious Mental Illness

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Obstructive Sleep Apnea of Adult

United States
Hospices Civils de Lyon

Recruiting

NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients. (NIRAPK)

Adult Patients With Platinum-sensitive, Relapsed, High Grade Serous Epithelial Ovarian Cancer

France
Beijing Anzhen Hospital

Recruiting

Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea (VISION)

Coronary Artery Disease | Obstructive Sleep Apnea of Adult

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (Magnetic Resonance Elastography) in Detecting Treatment Response in Patients With Advanced Liver Cancer

Advanced Adult Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma...

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Refractory B-Cell Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma | Relapsed Adult ALL | Relapsed CLL | Refractory B-Cell Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Non-Small Cell Lung Cancer | Leukemia-Lymphoma, Adult T-Cell

United States
Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of AZD3965 in Patients With Advanced Cancer

Adult Solid Tumor | Burkitt Lymphoma | Diffuse Large B Cell Lymphoma

United Kingdom
Bekasi City Public Hospital
University of Groningen

Completed

Usability Study of IeHS in Indonesia

Tuberculosis | Mobile Phone Use | Human Immunodeficiency Virus | Adult | Interpersonal Relations

Indonesia
National Cancer Institute (NCI)

Completed

Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage III Colon Cancer | Stage III Rectal Cancer

United States
European Organisation for Research and Treatment...

Completed

NGR-TNF in Treating Patients With Advanced Solid Tumors

Kidney Cancer | Head and Neck Cancer | Colorectal Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Germany, Netherlands
Yale University
Rheumatology Research Foundation

Recruiting

Rheumatology Patient Registry and Biorepository

Rheumatic Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Dermatomyositis | Polymyositis | Giant Cell Arteritis | Polymyalgia Rheumatica | Psoriatic Arthritis | Sjogren's Syndrome | Antiphospholipid Syndrome | Sarcoidosis | Lyme Disease | Ankylosing Spondylitis | Scleroderma | Reactive... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia in Remission | Refractory Anemia With Excess Blasts | Refractory... and other conditions

United States
University Hospital Southampton NHS Foundation...
University of Southampton

Active, not recruiting

HORIZONS: Understanding the Impact of Cancer Diagnosis and Treatment on Everyday Life

Cervical Cancer | Fallopian Tube Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Breast Neoplasm | Endometrial Neoplasms | Vulvar Cancer | Vulvar Neoplasms | Endometrial Cancer | Diffuse Large B Cell Lymphoma | Ovarian Neoplasm | Breast Cancer Female | Primary Peritoneal Carcinoma | NonHodgkin Lymphoma | Cervical... and other conditions

United Kingdom
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Small Lymphocytic... and other conditions

United States
Acerand Therapeutics (Shanghai) Limited

Recruiting

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Solid Tumor, Adult

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Retrospective Observational Study on Infective Complications and Outcome of Patients With ALL Treated With INO (INO-FIRST)

Infections | Bacterial Infections | Fungal Infection | Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia, in Relapse | Viral Infection | Acute Lymphoblastic Leukemia, Adult

Italy
Oliver Cornely, MD
German Federal Ministry of Education and Research; ZKS Köln

Recruiting

Immunogenicity of COVID-19 Vaccination in Autologous HSCT or CAR-T Cells Recipients (A-COV-V)

COVID-19 | Non Hodgkin Lymphoma | Hodgkin Lymphoma, Adult

Germany
Ana Broseta Lleó
Hospital General Universitario de Valencia

Recruiting

LUS to Assess Lung Injury After Lung Resection (THORUS)

Postoperative Complications | Lung Cancer | Lung Injury | Lung Injury, Ventilator Induced | Lung Neoplasm | Thoracic | Adult ALL | Lung Inflammation | Lung Ischemia/Hypoxia | Postoperative Respiratory Complication

Spain
National Cancer Institute (NCI)

Recruiting

Tissue Collection for Studies of Lymph Cancer

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Leukemia-Lymphoma, Adult T-Cell | Lymphomatoid Granulomatosis

United States, Jamaica

Clinical Trials on Elderly Adults

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