Clinical Trials on Elderly Subjects

Total 2218 results

Abbott
AbbVie; Parexel; Datamap; LKF Laboratorium für Klinische Forschung GmbH; Analytical... and other collaborators

Completed

Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Exocrine Pancreatic Insufficiency in Subjects With Cystic Fibrosis

Spain, Czech Republic, Hungary, Poland
Case Western Reserve University
University of Southern California

Active, not recruiting

Knowledge and Interpersonal Skills to Develop Exemplary Relationships (KINDER): Pilot Study (KINDER)

Dementia | Caregiver Burden | Elder Abuse | Relation, Family

United States
Buddhist Tzu Chi General Hospital

Recruiting

Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Healthy Subjects | Laryngopharyngeal Reflux

Taiwan
Oulu University Hospital

Unknown

Effect of the Nasal Provocation on the Breathing Style

Birch Pollen Allergy | Healthy Control Subjects

Finland
Ruhr University of Bochum

Completed

Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)

Healthy Subjects | Complex Regional Pain Syndrome Type I of the Upper Limb | Unilateral Limb Pain of Other Origin

Germany
Amgen

Completed

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

Bone Metastases in Men With Hormone-Refractory Prostate Cancer | Bone Metastases in Subjects With Advanced Breast Cancer | Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma

United Kingdom, Czech Republic
Centre integre universitaire de sante et de services...
Université de Montréal

Completed

COVID-19 Infections and Mortality in Long-term Care Facilities During the First Wave

Covid19 | Death | Elderly Infection | Infection Viral | Infections, Respiratory | Infection, Coronavirus | Old Age; Dementia | Epidemic Disease

Canada
University Medical Centre Ljubljana

Completed

Erythema Migrans in Elderly

Lyme Disease | Elderly Infection | Erythema Migrans
Amgen

Completed

Romiplostim (AMG 531) Versus Medical Standard of Care for Immune (Idiopathic) Thrombocytopenic Purpura

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura
GlaxoSmithKline

Completed

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline

Completed

DDI Study of Etravirine and GSK1265744

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Protease Inhibitors

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Oregon Health and Science University
University of Colorado, Denver; University of Iowa; University of Wisconsin,... and other collaborators

Active, not recruiting

Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks

Cardiovascular Diseases | Cancer | Chronic Obstructive Pulmonary Disease | Frail Elderly Syndrome | Cerebrovascular Accident | Congestive Heart Failure

United States, Canada
Peking University
National Natural Science Foundation of China

Recruiting

Long COVID and Its Associations With Health Outcomes in Older Adults

Reinfection | Vaccine Reaction | Long COVID | COVID-19 Pandemic | Elderly Infection | Lifestyle Factors

China
Oregon Health and Science University

Unknown

Acute Care for Elders (ACE) Program at OHSU Hospital

Delirium | Drug-Related Side Effects and Adverse Reactions | Frail Elderly | Age-Related Cognitive Decline | Hospital Acquired Pressure Ulcer

United States
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Completed

Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults

Depression | Anxiety | Depression in Old Age | Elder Abuse

United States
Medical University of Warsaw

Active, not recruiting

Effectiveness and Tolerability of Influenza Vaccine in Patients at Risk for Severe and Complicated Influenza

Obesity | Vaccine Adverse Reaction | Vaccine Reaction | Influenza | Tolerance | Pregnancy; Infection | Elderly Infection

Poland
Pontificia Universidad Catolica de Chile

Completed

Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM). (APOPM)

Urologic Diseases | Frail Elderly Syndrome | Surgery | Anesthesia | Nurse-Patient Relations | Perioperative Care | Older Adults | Old Age; Debility | Post-Operative Confusion | Digestive Disease

Chile
Chandan K Sen
Carotech Inc.

Completed

Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol

End Stage Liver Disease | Healthy Subjects | Morbid Obesity | Pulmonary Failure | End Stage Cardiac Failure | Recalcitrant Epilepsy Requiring Surgery

United States
Centre hospitalier de l'Université de Montréal...

Completed

Comparison of the QT/QTc Interval Between an Outpatient HIV-Infected Population on Antiretroviral Therapy and Two Large HIV-Negative Cohorts (QTVIE)

QT and Corrected QT Intervals Prolongation in HIV Positive Subjects Treated With an Antiretroviral Regimen

Canada
Amgen

Completed

Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | Thrombocytopenic Purpura
Axcella Health, Inc

Completed

To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | To Assess the Safety and Tolerabiltiy of an Amino Acid Composition in Subjects With Sickle Cell Disease | Sickle Cell Disorders

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

Subjects With p16 Positive/HPV Positive Squamous Cell Carcinomas of the Oropharynx

United States
Amgen

Completed

A Study Evaluating the Safety and Efficacy of Long-term Dosing of Romiplostim in Thrombocytopenic Pediatric Patients With Immune (Idiopathic) Thrombocytopenia Purpura

Thrombocytopenia in Pediatric Subjects With Immune Idiopathic Thrombocytopenic Purpura ITP

United States, Canada, Australia, Spain
University Hospital, Limoges

Terminated

Pilot Study of the Impact of Giant Cell Arteritis and Its Treatment on the Autonomy of the Elderly in the First Year of Care (EPACAPA)

Giant Cell Arteritis in Dependency of Elderly

France
Rijnstate Hospital

Unknown

Immunological Profiles in Inflammatory Bowel Disease (ImmunoIBD)

Crohn Disease | Ulcerative Colitis | Immunology | IBD | T Cell Subsets | Immunological Profiles

Netherlands
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Healthy Subject

United States
Hebrew Home at Riverdale
Weill Medical College of Cornell University; Cornell University

Completed

Resident-to-Resident Elder Mistreatment Intervention for Dementia Care in Assisted Living

Assisted Living, Resident to Resident Elder Mistreatment

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects

Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation

China
Shriners Hospitals for Children
The University of Texas Health Science Center, Houston; Oregon Health and Science... and other collaborators

Unknown

Development of a Blood Test for Marfan Syndrome

Marfan Syndrome | Marfan Related Disorders | Control Subjects

United States
Turku University Hospital

Active, not recruiting

Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis (SIGLEC)

Rheumatoid Arthritis | Vasculitis | Healthy Subjects | Pulmonary Sarcoidosis

Finland
Amgen

Completed

Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia

Subjects With Hyperlipidemia, Dyslipidemia and HIV Infection

Canada, France, United States, Belgium, Italy, Spain, Switzerland, United Kingdom, South Africa, Portugal, Australia, Greece, Brazil, Romania, Poland
Chulalongkorn University

Recruiting

Association Between Renal Reserve Function and Progression of Renal Function to Predict CKD Risk in Thai Elderly

Renal Function Abnormal | Elder

Thailand
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers

Sarcoma | Breast Carcinoma | Skin Carcinoma | Healthy Subject | Malignant Soft Tissue Neoplasm

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Predictive Tracking of Patient Flow in the Emergency Services During the Virus Winter Epidemics (PREDAFLU)

Child | Acute Renal Failure | Elderly | Bronchiolitis | Disease Outbreaks

France
Amsterdam UMC, location VUmc
GGZ inGeest; Parnassia Bavo Groep

Terminated

Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy

Multiple Sclerosis | Idiopathic Parkinson's Disease | Elderly Post Electric Convulsive Therapy

Netherlands
Chang Bing Show Chwan Memorial Hospital

Unknown

Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities

Wheel-chair Dependent Elders

Taiwan
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

GSK1349572 Hepatic Impairment Study

HIV Infections | Healthy Subjects | Hepatic Impairment | Infection, Human Immunodeficiency Virus

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

Head and Neck Cancer | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Healthy Subject

United States
Hospices Civils de Lyon

Completed

Sleep and Memory in Children (EnSOM)

Sleep Apnea | Narcolepsy | Healthy Subject | Temporo-central Epilepsy | High Intellectual Potential

France
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of ASP8232 in Subjects With Renal Impairment and in Type 2 Diabetes Mellitus Subjects With Chronic Kidney Disease

Healthy Subjects | Type 2 Diabetes Mellitus (T2DM) | Chronic Kidney Disease (CKD) | Pharmacokinetics of ASP8232 | Pharmacodynamics of ASP8232

Bulgaria, Moldova, Republic of, Romania
University Hospital, Strasbourg, France

Recruiting

Metabolomic Analysis of Systemic Sclerosis (SCLEROMICS)

Vascular Disease | Raynaud Disease | Healthy Control Subjects | Undifferentiated Connective Tissue Disease | Scleroderma (Limited and Diffuse)

France
Lotus Pharmaceutical

Unknown

A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus

The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg | Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in | Subjects With Type 2 Diabetes Mellitus.

Taiwan
The Cleveland Clinic

Active, not recruiting

A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery

Malnutrition | Esophageal Cancer | Lung Cancer | Frail Elderly Syndrome | Sarcopenia | Surgery | Surgery--Complications | Thoracic Neoplasm | Thoracic

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Bedside Bone Biopsy in Diabetic Foot Osteomyelitis (BOLBOC)

Subjects With Diabetes and DFU With a Suspicion of DFO

France
Guido A. Davidzon, MD, SM

Completed

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

Glioblastoma | Healthy Subject | Intracranial Neoplasm

United States
Karen Brorup Heje Pedersen

Completed

High Intensity Training in Patients With Spinal and Bulbar Muscular Atrophy (HIT in Kennedy)

Healthy Subjects | Spinal and Bulbar Muscular Atrophy

Denmark
Yonsei University

Completed

Predictors of Postoperative Delirium in Elder Patients After Spine Surgery: Regional Cerebral Oxygen Saturation

Postoperative Delirium in Elder Patients After Spine Surgery

Korea, Republic of
Danone Research

Completed

Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers

Respiratory Tract Infections | Pneumonia | Gastroenteritis | Sinusitis | Influenza | Healthy Subjects | Otitis | Infectious Diseases | Bronchitis | Sore Throat

Germany

Clinical Trials on Elderly Subjects

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Serbia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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