Clinical Trials on Encephalomyelitis, Autoimmune, Experimental in Czechia

Total 558 results

UCB Pharma

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
Bristol-Myers Squibb

Completed

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, United States, Argentina, Brazil, Canada, Mexico, Peru, Korea, Republic of, Sweden, Australia, Russian Federation, Poland, Puerto Rico, Czech Republic, Denmark, South Africa, Switzerland
Novartis Pharmaceuticals

Terminated

Secukinumab Efficacy and Safety Study in Patients With Rheumatoid Arthritis and Inadequate Response to Anti-TNFα Agents. (REASSURE2)

Rheumatoid Arthritis

United States, Germany, Greece, Argentina, Brazil, Colombia, Czech Republic, Dominican Republic, Guatemala, India, Italy, Japan, Korea, Republic of, Panama, Portugal, South Africa
AbbVie (prior sponsor, Abbott)

Completed

Study to Determine the Effects of Different Doses of Methotrexate (MTX) When Taken With Adalimumab in Subjects With Early Rheumatoid Arthritis (RA) (CONCERTO)

Early Rheumatoid Arthritis

United States, Argentina, Austria, Belgium, Canada, Czech Republic, Germany, Poland, Puerto Rico, Spain
Boehringer Ingelheim
Eli Lilly and Company

Completed

Empagliflozin as Adjunctive to InSulin thErapy Over 52 Weeks in Patients With Type 1 Diabetes Mellitus (EASE-2)

Diabetes Mellitus, Type 1

United States, Spain, Taiwan, Belgium, United Kingdom, Germany, Canada, Australia, Finland, Netherlands, Poland, France, Denmark, Norway, Sweden, Austria, Czechia
Sanofi

Completed

Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus (EDITION JUNIOR)

Type 1 Diabetes Mellitus

France, Czechia, Chile, Israel, Spain, Hungary, Mexico, Serbia, Japan, Canada, Brazil, Sweden, Denmark, Argentina, United States, Bulgaria, Germany, Italy, Latvia, North Macedonia, Poland, Romania, Russian Federation, United Kingdom
AbbVie

Completed

A Study Comparing Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone (SELECT-NEXT)

Rheumatoid Arthritis

United States, Argentina, Australia, Austria, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Estonia, Finland, France, Germany, Greece, Hong Kong, Hungary, Ireland, Italy, Kazakhstan, Korea, Republic of, Latvia, Lithuan... and more
R-Pharm International, LLC
Quintiles, Inc.; OCT Clinical Trials

Completed

Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo and Adalimumab, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease (CREDO 2)

Rheumatoid Arthritis

United States, Germany, Korea, Republic of, Bulgaria, Poland, Taiwan, Mexico, Hungary, Czechia, United Kingdom, Lithuania, Argentina, Brazil, Colombia, Estonia, Latvia, Russian Federation, Romania
AbbVie

Completed

A Study to Compare Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) With an Inadequate Response or Intolerance to Biologic DMARDs (SELECT-BEYOND)

Rheumatoid Arthritis

United States, Australia, Austria, Belgium, Canada, Czechia, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Korea, Republic of, Latvia, New Zealand, Poland, Portugal, Puerto Rico, Russian Federation, Slovakia, ... and more
Eli Lilly and Company

Completed

A Study in Moderate to Severe Rheumatoid Arthritis (RA-BEAM)

Rheumatoid Arthritis

Argentina, Korea, Republic of, United States, Spain, China, Hungary, Romania, Poland, Belgium, Czechia, France, Japan, Mexico, Russian Federation, United Kingdom, Puerto Rico, Portugal, Greece, Taiwan, Latvia, South Africa, Canada, ... and more
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients (RA-MOBILITY)

Rheumatoid Arthritis

Germany, Hungary, Belgium, United States, Argentina, Australia, Austria, Belarus, Brazil, Canada, Chile, Czechia, Estonia, Finland, Greece, Korea, Republic of, Lithuania, Malaysia, Mexico, New Zealand, Philippines, Poland, Romania, Russian... and more
GlaxoSmithKline
Iqvia Pty Ltd

Terminated

Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA) (contRAst X)

Arthritis, Rheumatoid

United States, Germany, Japan, Korea, Republic of, Poland, Ukraine, Bulgaria, Canada, Czechia, Estonia, Hungary, Mexico, Russian Federation, South Africa, Spain, Malaysia, Thailand, China, Argentina, Belgium, India, United Kingdom, ... and more
Hoffmann-La Roche
Genentech, Inc.

Completed

Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Belgium, Germany, Poland, Spain, United States, Canada, Mexico, New Zealand, United Kingdom, Finland, Israel, Italy, Sweden, Australia, Brazil, Czech Republic
Bristol-Myers Squibb

Terminated

An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

Lupus Nephritis

United States, Taiwan, Spain, United Kingdom, Netherlands, Germany, China, Australia, Belgium, Mexico, Korea, Republic of, Czechia, Russian Federation, Israel, Canada, Italy
Takeda

Terminated

VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis (VELVET)

Rheumatoid Arthritis

United States, Argentina, Canada, Czech Republic, Germany, Hungary, Italy, Mexico, Poland, Spain, United Kingdom
Novo Nordisk A/S

Completed

Comparison of Insulin Detemir Plus Insulin Aspart With Insulin NPH Plus Human Soluble Insulin in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Croatia, Italy, Slovakia, Denmark, Macedonia, The Former Yugoslav Republic of, Norway, Russian Federation, Finland, France, Poland, Greece, Romania, Sweden, Czech Republic, Argentina
Bristol-Myers Squibb

Completed

Effects of Abatacept in Patients With Early Rheumatoid Arthritis (AVERT-2)

Rheumatoid Arthritis

Italy, Sweden, Taiwan, United States, Peru, Germany, Mexico, Japan, Israel, Spain, Czechia, Argentina, Brazil, Colombia, Romania, Australia, France, Poland, Singapore, Russian Federation, South Africa, Canada, United Kingdom, Hungary, C... and more
Gilead Sciences
Galapagos NV

Completed

Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate (FINCH 1)

Rheumatoid Arthritis

United States, Italy, Poland, Ukraine, Belgium, Hong Kong, Taiwan, Spain, Israel, Bulgaria, India, Serbia, South Africa, Korea, Republic of, Japan, Russian Federation, Argentina, Germany, New Zealand, Thailand, Hungary, Netherlands, Slovaki... and more
Sanofi
Regeneron Pharmaceuticals

Terminated

An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus Methotrexate (RA-COMPARE)

Rheumatoid Arthritis

United States, Argentina, Australia, Brazil, Chile, Czechia, Finland, Germany, Greece, Hungary, Israel, Italy, Korea, Republic of, Lithuania, Malaysia, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine, F... and more
AstraZeneca

Terminated

Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA) (OSKIRA -4)

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Poland, Russian Federation, South Africa, United Kingdom, Hungary, Ukraine, Germany, Netherlands, Canada, Slovakia
Sanofi
Regeneron Pharmaceuticals

Completed

Long Term Evaluation of Sarilumab in Rheumatoid Arthritis Patients (SARIL-RA-EXTEND)

Rheumatoid Arthritis

United States, Argentina, Australia, Austria, Belarus, Belgium, Brazil, Canada, Chile, Colombia, Czechia, Ecuador, Estonia, Finland, Germany, Greece, Guatemala, Hungary, Israel, Italy, Korea, Republic of, Lithuania, Malaysia, Mexico, Ne... and more
Genentech, Inc.
Roche Pharma AG

Terminated

A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Response to Anti-TNF-α Therapy (SCRIPT) (SCRIPT)

Rheumatoid Arthritis

United States, Belgium, Canada, Hungary, Argentina, Germany, Spain, Brazil, Poland, Israel, Mexico, Japan, France, Peru, Switzerland, Sweden, Italy, Australia, New Zealand, Panama, Czechia, Netherlands, Slovakia, Slovenia, Taiwan
Pfizer

Completed

Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Spain, Korea, Republic of, Taiwan, China, France, Belgium, Denmark, Bulgaria, Czechia, Hungary, India, Slovakia, Croatia, Turkey, Mexico, Canada, Germany, Argentina, Poland, Puerto Rico, Malaysia, Brazil, Australia, Romania, United Kingdom and more
Swedish Orphan Biovitrum

Recruiting

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE (EMERALD)

Systemic Lupus Erythematosus | Macrophage Activation Syndrome | Still Disease | Secondary Hemophagocytic Lymphohistiocytosis | SJIA | AOSD | MAS

United States, Belgium, Italy, Netherlands, United Kingdom, China, France, Spain, Czechia, Canada, Sweden, Japan, Germany, Poland
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, China, United States, France, Sweden, South Africa, Czech Republic, Australia, Germany, Russian Federation, Canada, Thailand, Mexico, Hong Kong, Brazil, Argentina, Panama, Costa Rica, Finland
R-Pharm International, LLC
IQVIA Pvt. Ltd; OCT Clinical Trials

Completed

Efficacy and Safety of Olokizumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis (CREDO 4)

Rheumatoid Arthritis

Korea, Republic of, United States, Germany, Hungary, Bulgaria, Poland, Taiwan, Mexico, Czechia, Argentina, United Kingdom, Belarus, Brazil, Colombia, Estonia, Latvia, Lithuania, Russian Federation
Pfizer

Completed

A Phase 3 Study Comparing 2 Doses Of CP-690,550 And The Active Comparator, Humira (Adalimumab) Vs. Placebo For Treatment Of Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Costa Rica, Czech Republic, Germany, Croatia, Canada, Korea, Republic of, Spain, Bosnia and Herzegovina, Australia, Bulgaria, Mexico, Slovakia, Poland, Philippines, Chile, Denmark, Dominican Republic, Finland, T... and more
AbbVie

Completed

A Phase 3 Study to Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Rheumatoid Arthritis (RA)

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Czechia, Germany, Greece, Hungary, Ireland, Israel, Italy, Korea, Republic of, Latvia, Mexico, Netherlands, New Zealand, Poland, Portugal, Puerto Rico, Romania, Russian... and more
Amgen

Completed

Interventional Study in Adults With Immune Thrombocytopenia Purpura (ITP) Receiving Romiplostim

Idiopathic Thrombocytopenic Purpura

Italy, United States, Germany, Czechia, United Kingdom, Australia, Spain, Poland, France
Calliditas Therapeutics AB

Completed

The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease (NEFIGAN)

Primary IgA Nephropathy

Belgium, United Kingdom, Denmark, Finland, Sweden, Germany, Spain, Italy, Czech Republic, Netherlands
Provention Bio, Inc.

Completed

Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab (PROTECT)

Type 1 Diabetes Mellitus

United States, Belgium, Canada, Czechia, France, Germany, Hungary, Poland, United Kingdom
Galapagos NV
Gilead Sciences

Active, not recruiting

Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Adults With Rheumatoid Arthritis (FINCH 4)

Rheumatoid Arthritis

Spain, United States, Japan, Korea, Republic of, Taiwan, Belgium, India, Malaysia, Argentina, Australia, Poland, Czechia, Serbia, Germany, New Zealand, Bulgaria, Canada, Chile, France, Hong Kong, Hungary, Ireland, Israel, Italy, Mexico, R... and more
Novo Nordisk A/S

Terminated

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Methotrexate

Inflammation | Rheumatoid Arthritis

United States, Mexico, Russian Federation, France, Italy, Spain, Argentina, Belgium, Brazil, Czechia, Germany, Poland, Ukraine, Hungary
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

Juvenile Idiopathic Arthritis

Belgium, Italy, Spain, United States, Greece, Germany, Australia, Brazil, Argentina, Canada, United Kingdom, Poland, Denmark, Norway, Mexico, Slovakia, Sweden, Czech Republic, Netherlands
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis (PREMIER)

Early Rheumatoid Arthritis

United States, Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, Norway, Slovakia, Spain, Sweden, Switzerland, United Kingdom
AbbVie

Completed

A Study to Compare Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have Not Previously Taken Methotrexate (SELECT-EARLY)

Rheumatoid Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Guatemala, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, K... and more
Rigel Pharmaceuticals

Completed

Open Label Study of R788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)

Immune Thrombocytopenic Purpura

Spain, United States, Australia, Poland, United Kingdom, Canada, Czechia, Bulgaria, Romania, Austria, Denmark, Hungary, Italy, Netherlands, Norway
Eli Lilly and Company
Incyte Corporation

Active, not recruiting

A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA-BRIDGE)

Rheumatoid Arthritis

Spain, United States, Hungary, Australia, Turkey, Czechia, Belgium, United Kingdom, Poland, Puerto Rico, Israel, Switzerland, France, South Africa, Romania, Italy, Germany, Netherlands, Austria, Denmark, Lithuania, Russian Federation and more
Boehringer Ingelheim
Eli Lilly and Company

Completed

Empagliflozin as Adjunctive to Insulin Therapy Over 26 Weeks in Patients With T1DM (EASE-3)

Diabetes Mellitus, Type 1

United States, United Kingdom, Canada, Italy, Hungary, Spain, Sweden, Australia, Netherlands, France, Czechia, Finland, Germany, Greece, Ireland, Latvia, Mexico, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, South...
AstraZeneca

Completed

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist (OSKIRA - 3)

Rheumatoid Arthritis

United States, Czech Republic, Mexico, South Africa, Spain, United Kingdom, Germany, Argentina, Belgium, Canada, Hungary, Israel, Portugal, France, Brazil, Italy
Bristol-Myers Squibb

Completed

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

Rheumatoid Arthritis

Belgium, Spain, United States, Germany, Italy, Mexico, United Kingdom, France, Czech Republic, Ireland
Novo Nordisk A/S

Completed

Efficacy and Safety of FIAsp Compared to Insulin Aspart Both in Combination With Insulin Detemir in Adults With Type 1 Diabetes (onset® 1)

Diabetes | Diabetes Mellitus, Type 1

United States, Poland, Finland, Belgium, Hungary, United Kingdom, Germany, Canada, Czechia
MacroGenics
Eli Lilly and Company

Terminated

Protege Encore Study- Clinical Trial of Teplizumab (MGA031) in Children and Adults With Recent-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States, Israel, United Kingdom, Poland, France, Germany, Belgium, Finland, India, Ukraine, Spain, Czechia, Italy, Mexico, Netherlands, Romania
AstraZeneca

Completed

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding. (OSKIRA - 2)

Rheumatoid Arthritis

United States, Czech Republic, Spain, United Kingdom, Latvia, Lithuania, Romania, Ukraine, Canada, Israel, Portugal, Germany, South Africa, Serbia, India, Italy
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Rheumatoid Arthritis

United States, Italy, United Kingdom, Austria, France, Germany, Canada, Argentina, Belgium, Croatia, Bosnia and Herzegovina, Latvia, Spain, Hungary, Czechia, Malaysia, Russian Federation, Serbia, Israel, Poland, Turkey, Netherlands, Greec... and more
Bristol-Myers Squibb

Completed

Remission and Joint Damage Progression in Early Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Spain, Puerto Rico, Belgium, Australia, Canada, Mexico, France, Germany, Netherlands, Russian Federation, South Africa, United Kingdom, Brazil, Czech Republic, Italy, Poland
Eli Lilly and Company

Recruiting

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)

Systemic Juvenile Idiopathic Arthritis

Belgium, Spain, India, Italy, Czechia, Japan, Austria, France, United Kingdom, Brazil, Mexico, Israel, Poland, Argentina, Denmark, Turkey
Sanofi

Completed

6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes (PRESCHOOL)

Type 1 Diabetes Mellitus

United States, Austria, Brazil, Chile, Czech Republic, Germany, Hungary, India, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Turkey
Hoffmann-La Roche

Completed

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Rheumatoid Arthritis

Belgium, Czech Republic, France, Italy, Spain, Sweden, United Kingdom, Canada, Greece, Ireland, Portugal, Turkey, Netherlands, Denmark, Finland, Germany, Luxembourg, Austria, Switzerland, Poland, Australia, Hungary, Saudi Arabia, Romania and more
Eli Lilly and Company

Completed

An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis (RA-BEYOND)

Rheumatoid Arthritis

United States, Canada, Puerto Rico, China, Spain, Australia, Japan, India, Portugal, Germany, Turkey, Switzerland, Mexico, Poland, Belgium, France, Hungary, Korea, Republic of, Russian Federation, Taiwan, Israel, Austria, Italy, Argen... and more

Clinical Trials on Encephalomyelitis, Autoimmune, Experimental in Czechia

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CROs in Rwanda

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