Clinical Trials on Endotoxemia

Total 78 results

Herlev Hospital

Completed

Antiinflammatoric and Antioxidative Effect of Melatonin in Human Endotoxaemia

Human Endotoxaemia

Denmark
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Petrovsky National Research Centre of Surgery

Recruiting

Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) (РМХ vs SS)

Multiple Organ Dysfunction With Severe Endotoxemia

Russian Federation
Alteco Medical AB

Withdrawn

Remove LPS Registry

Suspected or Diagnosed Endotoxemia Casued by Gram-negative Bacteria
Danisco

Completed

Probiotics and Endotoxemia (PROMS-01)

Metabolic Syndrome | Metabolic Endotoxemia

France
Ohio State University

Completed

Alleviation Of Metabolic Endotoxemia In Adults With Metabolic Syndrome With Milk Fat Globule Membrane

Metabolic Syndrome | Metabolic Endotoxemia

United States
Iowa State University

Completed

The Role of Dietary Fat on Postprandial Endotoxemia in Healthy Adults

Endotoxemia

United States
Radboud University Medical Center
Maastricht University Medical Center

Completed

Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental Endotoxemia (VIHE)

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

Effects of Vasopressors on Immune Response

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

Ticagrelor in Human Endotoxemia Response to Human Endotoxemia

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

A Possible Therapeutic Role for Adenosine During Inflammation

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

Effect of Selective iNOS Inhibition During Human Endotoxemia

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human Endotoxemia (SALYCENDO)

Endotoxemia

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

The Role of the Gut Microbiota in the Systemic Immune Response During Human Endotoxemia (MISSION-2)

Endotoxemia

Netherlands
Rutgers, The State University of New Jersey

Completed

The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers

Infections

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Blockade of Vascular Potassium Channels During Human Endotoxemia

Endotoxemia
Medical University of Vienna

Completed

Anti-Inflammatory Effect of Statins in the Human Endotoxin Model

Endotoxemia

Austria
Medical University of Vienna

Completed

Ethnic Differences in the Inflammatory Response in Systemic Inflammation

Endotoxemia

Austria
University of Vienna

Completed

Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function

Endotoxemia | Dietary Habits

Austria
University of Vienna

Completed

Cereals and Intestinal Function

Endotoxemia | Diet, Healthy

Austria
Bernd Jilma

Completed

Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of Defibrotide (LPS_DF)

Endotoxemia | Healthy Volunteers

Austria
Prof. Dr. Ina Bergheim

Completed

Effect of Monosaccharides on Intestinal Barrier Function (ENDO-META)

Endotoxemia | Dietary Habits
Rutgers, The State University of New Jersey

Completed

The Effects of Epinephrine in Endotoxemia in Normal Volunteers (Epi)

Immune System

United States
University of Vienna

Recruiting

Different Dietary Patterns

Endotoxemia | Diet, Healthy

Austria
Medical University of Vienna

Completed

Vorapaxar in the Human Endotoxemia Model

Healthy Volunteers

Austria
Radboud University Medical Center
CoMentis

Completed

Anti-inflammatory Effects of GTS-21 After LPS

Sepsis | Endotoxemia | Vagal Activity

Netherlands
Radboud University Medical Center

Completed

Pathophysiology and Clinical Relevance of Endotoxin Tolerance in Humans

Endotoxemia

Netherlands
University of Pennsylvania

Completed

The Genetics of Evoked Responses to Niacin and Endotoxemia: The GENE Study (GENE)

Healthy Volunteers

United States
Green Beat

Completed

Probiotic Sport Study

Inflammation | Endotoxemia | Oxidative Stress

Austria
Herlev Hospital

Unknown

Low-Dose Endotoxemia and the Acute Phase Response

Sepsis | Endotoxemia

Denmark
University of Glasgow

Completed

ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight Adults (ENDOCUR)

Overweight
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); GlaxoSmithKline

Completed

Fenofibrate and Omega-3 Fatty Acid Modulation of Endotoxemia (FFAME)

Cardiovascular Disease

United States
Radboud University Medical Center

Completed

The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Radboud University Medical Center
UMC Utrecht; Prothya Biosolutions

Completed

In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II (VECTORII)

Sepsis | Inflammation | Endotoxemia | Innate Immune Response

Netherlands
Penn State University
United States Department of Agriculture (USDA)

Completed

Safety and Feasibility of an Endotoxemia Model

Inflammation | Cardiovascular Disease

United States
University of Aarhus
Aarhus University Hospital; Arla Food Ingrediens

Completed

Gastro-intestinal and Hormonal Responses to Systemic Inflammatory Disease

Endotoxemia | Motility Disorder | Catabolic State

Denmark
Ohio State University

Active, not recruiting

Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults

Inflammation | Obesity | Endotoxemia

United States
Spectral Diagnostics (US) Inc.

Temporarily not available

Open-label Evaluation of Polymyxin B Hemoperfusion for Septic Shock (EUPHORIA)

Septic Shock | Endotoxemia
University of Aarhus
Aarhus University Hospital Skejby; Arla Food Ingredients, Arla Viby.

Completed

Echocardiographic Changes After 3-hydroxy Butyrate+Whey Intake

Endotoxemia | Cardiac Output | Echocardiography | Catabolic State

Denmark
Spectral Diagnostics (US) Inc.

Completed

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock (EUPHRATES)

Septic Shock | Endotoxemia

United States, Canada
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Sevelamer for Reducing Endotoxemia and Immune Activation

HIV-1 Infection

United States
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
Spectral Diagnostics (US) Inc.

Recruiting

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Septic Shock | Endotoxemia

United States
Radboud University Medical Center

Completed

The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
University of Aarhus
Aarhus University Hospital; Arla Foods Ingredients

Completed

Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease Model

Endotoxemia | Muscle Loss | Nutrition Therapy | Protein; Disease | Catabolic State

Denmark
Medical University of Gdansk
Pomeranian Medical University Szczecin

Recruiting

The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery

Dysbiosis | Bariatric Surgery Candidate

Poland
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human Endotoxemia

Anemia | Systemic Inflammatory Process

Clinical Trials on Endotoxemia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mexico

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations