Clinical Trials on Eosinophilic Chronic Rhinosinusitis

Total 32858 results

Our Lady of the Lake Hospital
Louisiana State University Health Sciences Center in New Orleans

Recruiting

TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality

Rhinosinusitis Chronic | Sinus Cancer | Sinus Polyp | Encephalocele

United States
Weill Medical College of Cornell University

Withdrawn

Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis

Chronic Sinusitis | Rhinosinusitis

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative Disorders

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult... and other conditions

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab in CRSsNP (Liberty CRSsNP)

Chronic Sinusitis | Sinusitis | Chronic Rhinosinusitis Without Nasal Polyps | Sinus Disorder | Respiratory Disorder

Belgium, Spain, Argentina, Ukraine, Portugal, China, United States, Canada, Chile, Hungary, Korea, Republic of, Russian Federation, Sweden
Keymed Biosciences Co.Ltd

Not yet recruiting

A Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyposis （CROWNS-2）

Chronic Rhinosinusitis With Nasal Polyposis
Saffron Pharma

Completed

Efficacy and Safety of New Mometasone Furoate Nasal Spray Formulation in Acute Rhinosinusitis Patients: A Randomized Clinical Trial

Acute Rhinosinusitis

Pakistan
Organon and Co

Completed

Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Study P02683)

Acute Rhinosinusitis
Chiesi Farmaceutici S.p.A.

Completed

beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study (CLEAR)

Acute Rhinosinusitis

Italy
Oregon Health and Science University
Medical University of South Carolina; University of Pennsylvania; Northwestern...

Completed

Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study

Sinusitis | Chronic Rhinosinusitis

United States
University Hospital, Ghent

Completed

A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy

Debilitating Fibrosing Skin Disorders (Localised Scleroderma, Eosinophilic Fasciitis)

Belgium
National Cancer Institute (NCI)

Terminated

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Unspecified Adult Solid Tumor, Protocol Specific | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Mayo Clinic
AstraZeneca

Completed

The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis

Gastroesophageal Reflux Disease | GERD | Eosinophilic Esophagitis | EE

United States
Organon and Co

Completed

Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Phase 3 Study)(Study P02692)

Acute Rhinosinusitis
Edward Via Virginia College of Osteopathic Medicine
American Osteopathic Association

Completed

The Effect of Facial Effleurage on Acute Rhinosinusitis

Rhinosinusitis Acute

United States
Bitop AG

Completed

Non-interventional Study With Ectoin Containing and/or Decongesting Nasal Spray in Patients With Rhinosinusitis

Acute Rhinosinusitis

Germany
Bitop AG

Completed

Non-interventional Study of Ectoin Nasal Douche (END01) in Patients With Acute Viral Rhinosinusitis

Acute Rhinosinusitis

Germany
Bionorica SE

Completed

Efficacy and Safety of a Herbal Medicinal Product (Dry Extract BNO 1016) in Patients With Acute Rhinosinusitis

Acute Rhinosinusitis

Germany
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study (MEPOREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Medical University of South Carolina

Recruiting

Mechanisms of Smell Improvement With Dupilumab.

Chronic Rhinosinusitis With Nasal Polyps

United States
University Hospital, Strasbourg, France

Completed

Self-assessment of Olfactory Disorders for French Speaking Patients (VIF-DOR)

Chronic Rhinosinusitis | Post-viral Anosmia | Post-traumatic Anosmia | Idiopathic Anosmia | Age-related Loss of Smell

France
Fondazione Policlinico Universitario Agostino Gemelli...

Active, not recruiting

Dupilumab in the Treatment of Severe Uncontrolled CRSwNP: a Multicentre Observational Real-life Study (DUPIREAL) (DUPIREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Acclarent

Terminated

Clinical Evaluation of the Ethmoid Sinus Spacer (SPACER)

Sinusitis, Chronic Rhinosinusitis

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Helse Midt-Norge

Completed

Cleaning of the Nose After Sinus Surgery: Necessary or Only Bothersome?

Acute Recurrent Rhinosinusitis

Norway
Novartis Pharmaceuticals

Terminated

A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Zheng Liu

Completed

Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data

Progression | Chronic Sinusitis | Surgery | Radiology | Pathology

China
National Cancer Institute (NCI)

Terminated

Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
University Hospital, Lille

Recruiting

BIOlogics in Severe Nasal POlyposis SurvEy (BIOPOSE)

Chronic Rhinosinusitis With Nasal Polyps

France
Universitaire Ziekenhuizen KU Leuven

Completed

Prevalence of Nasal Hyperreactivity in Chronic Upper Airway Inflammation

Chronic Rhinosinusitis (Diagnosis) | Chronic Rhinitis | Hyperactivity | Upper Respiratory Disease

Belgium
Centre hospitalier de l'Université de Montréal...

Recruiting

Identifying Predictors Of Response To Mepolizumab In CRSwNP (ISS-RESMEPO)

Chronic Rhinosinusitis With Nasal Polyps

Canada
Sanofi
Regeneron Pharmaceuticals

Completed

Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps (SINUS-52)

Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)

Belgium, Mexico, Turkey, Israel, Spain, Sweden, Argentina, Canada, Japan, United States, Australia, Chile, Portugal, Russian Federation
Sanofi
Regeneron Pharmaceuticals

Recruiting

Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France (OPALE)

Chronic Rhinosinusitis With Nasal Polyposis

France, Réunion
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) (AROMA)

Chronic Rhinosinusitis With Nasal Polyposis

United States, Italy, Canada, Japan, Germany, Netherlands
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Mediators in Nasal Hyperreactivity in Allergic Rhinitis and Chronic Rhinosinusitis

Chronic Rhinosinusitis With Nasal Polyps | Hyperactivity | Allergic Rhinitis Due to House Dust Mite

Belgium
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Correlation Between the Microbiome and Type 2 Inflammatory Diseases of CRSwNP

Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
Radboud University Medical Center

Completed

Treatment With High Dose Methotrexate in Patients With Eosinophilic Fasciitis

Fasciitis

Netherlands
Beijing Tongren Hospital

Not yet recruiting

CST1-Guided Oral Glucocorticoids Management for CRSwNP (COMPASS)

Chronic Rhinosinusitis With Nasal Polyps | Glucocorticoids

China
IHU Strasbourg

Terminated

Evaluation of Patient Satisfaction During Treatment With Dupilumab in Severe and Recurrent Nasosinusal Polyposis Despite Appropriate Medical and Surgical Treatment. (Dupi-PNS)

Chronic Rhinosinusitis With Nasal Polyps

France
NorthShore University HealthSystem

Completed

Study for the Management of Pediatric Chronic Rhinosinusitis With or Without Balloon Sinuplasty

Rhinitis + Sinusitis, Pediatric Chronic Rhinosinusitis

United States
Neutec Ar-Ge San ve Tic A.Ş

Recruiting

Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis.

Sinusitis | Rhinosinusitis | Sinus Infection | Sinusitis, Acute | Rhinosinusitis Acute

Turkey
Nucera Eleonora

Recruiting

Survey About the Relationship Beetween Allergic Rhinitis and Seasonal EOE Exacerbations

Eosinophilic Esophagitis | Respiratory Allergy

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps (SINUS-24)

Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)

Italy, Ukraine, Hungary, United States, Bulgaria, Czechia, France, Germany, Netherlands, Poland, Romania, Russian Federation, United Kingdom
National Cancer Institute (NCI)

Terminated

Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
GlaxoSmithKline

Completed

Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and Eosinophilia Among Primary Care Patients

Pulmonary Disease, Chronic Obstructive

Brazil
William Shomali
Incyte Corporation

Recruiting

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Eosinophilia | Hypereosinophilic Syndrome | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Splenomegaly | Hepatomegaly | Chronic Eosinophilic Leukemia, Not Otherwise Specified | JAK2 Gene Mutation | BCR-JAK2 Fusion Protein Expression | Blasts 20 Percent or Less of Peripheral Blood White... and other conditions

United States
University Medical Center Groningen
GlaxoSmithKline; Maastricht University

Recruiting

Drivers of Eosinophilic COPD Exacerbations (DICE)

Eosinophilia | COPD Exacerbation

Netherlands
Vibeke Backer

Recruiting

Mepolizumab to CRSwNP Through 12 Months - Randomised to FESS and Non-FESS Within the First 2 Weeks

Asthma | Chronic Rhinosinusitis With Nasal Polyps

Denmark
National Cancer Institute (NCI)

Completed

Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
Wen Zhang
Beijing Friendship Hospital; Tongji Hospital

Recruiting

Baricitinib Plus Glucocorticoid for Eosinophilia in IgG4-RD

IgG4-related Disease With Eosinophilia

China
National Cancer Institute (NCI)

Completed

XK469R in Treating Patients With Refractory Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States

Clinical Trials on Eosinophilic Chronic Rhinosinusitis

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