Clinical Trials on Epigenetics

Total 44 results

Elysium Health
Duke Clinical Research Institute

Suspended

Biomarker Study to Evaluate Correlations Between Epigenetic Aging and NAD+ Levels in Healthy Volunteers

Epigenetics

United States
Huazhong University of Science and Technology

Unknown

The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil

Epigenetics

China
Northwestern University

Completed

Examining the Effects of Juice Fasting

Epigenetics | Microbiome

United States
Radboud University Medical Center

Active, not recruiting

BCG-induced Epigenetic Modifications in the NEXT Generation (NEXT)

Epigenetics | Trained Immunity | BCG Vaccine

Netherlands
IRCCS Eugenio Medea

Recruiting

Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience

Emotional Regulation | Epigenetics | Neurodevelopmental Disabilities | Parental Factors

Italy
Intervene Immune, Inc.

Recruiting

Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X)

Immunosenescence | Epigenetic Aging

United States
Unity Health Toronto

Completed

Effects of Maternal Folate and Folic Acid Supplementation on DNA Methylation in the Newborn Infant

Pregnancy | Epigenetics | Maternal Nutrition | Fetal Health | Maternal B Vitamins

Canada
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Completed

Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock (Topical-RAPA)

Aging | Epigenetics | Inflammatory Mediators

United States
University of Sao Paulo

Completed

DNA Methylation Profile of the SOCS-1 Gene Promoter in Smokers Patients With Chronic Periodontitis.

Periodontal Diseases | Epigenetics

Brazil
Origin Sciences

Completed

Exploratory Study of Rectal Mucus for Diagnosing Disease (ORI-EGI-02)

Bowel Cancer | Bowel Disease | Epigenetic Disorder | Genomic

United Kingdom
Istanbul University - Cerrahpasa (IUC)
Scientific Research Project Coordination Unit of Istanbul University-Cerrahpasa

Active, not recruiting

LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes

Cardiovascular Diseases | Hot Flashes | Sleep | Menopause | Epigenetics | DNA Methylation

Turkey
University of Tennessee

Completed

Opioid Physiology Project (OPP)

Addiction | Tolerance | Epigenetic Changes | Withdrawal

United States
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University of Aberdeen

Not yet recruiting

Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children (MINUTES)

Stunting | Nutrition | Epigenetics | DNA Methylation | Development, Child
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Milan; Italian Air Force; A-Tono; Ministry of Defense, Italy

Recruiting

TORNADO-Omics Techniques and Neural Networks for the Development of Predictive Risk Models

Cardiovascular Risk Factor | Discogenic Pain | Neuroplasticity | Epigenetic Changes | Stress Physiological | Space Maintenance | Oxidative Injury | LONGEVITY 1 | NGS

Italy
IVI Barcelona

Unknown

Epigenetic and Genetic Effects in Cancer Patients: Analysis Pre and After Treatment

Cancer | Male Infertility | Epigenetic Disorder

Spain
University of British Columbia
Johnson & Johnson Consumer Inc. (J&JCI); Genome British Columbia

Active, not recruiting

Epigenetic Health Benefits of Budesonide (Project Ace)

Environmental Exposure | Epigenetic Effects of Intranasal Steroids

Canada
University of Copenhagen
Lund University; Aarhus University Hospital; National Institute for Medical Research... and other collaborators

Completed

Foetal Exposure and Epidemiological Transition: Role of Anaemia in Early Life for Non-communicable Diseases Later (FOETALforNCD)

Epigenetics | Anemia and Pregnancy | Metabolism and Foetal Growth

Tanzania
IRCCS Eugenio Medea

Recruiting

Epigenetics and Protective Factors in the Preterm Infant (EPIC)

Preterm Birth | Parent-Child Relations | Epigenetics

Italy
University of Copenhagen
Deakin University; Monash Health

Completed

Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins (FEASST)

Overnutrition | Fertility Issues | Nutrition, Healthy | Epigenetic Disorder

Denmark
University Hospital, Basel, Switzerland
Friedrich Miescher Institute for Biomedical Research (FMI)

Completed

Human Sperm Epigenetics in Embryonic Development. (EPI)

Male Infertility | Epigenetic Disorder

Switzerland
Carlos Wambier
Brown University; Sun Pharmaceutical Industries Limited; Lifespan; Ocean State...

Active, not recruiting

Effects of Tildrakizumab on Epigenetic Age

Psoriasis | Aging | Inflammation; Skin | Epigenetic Disorder

United States
IRCCS Eugenio Medea

Recruiting

Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls

Preterm Birth | Parent-Child Relations | Epigenetics

Italy
Jeadran N. Malagón-Rojas

Not yet recruiting

Effects of "Vitamin N" Nature Immersion Therapy on Stress Levels in Health Care Workers in the City of Bogotá

Stress, Psychological | Anxiety | Environmental Exposure | Cortisol Excess | Epigenetic Disorder | Natural Killer Cell Cytokine Production

Colombia
Medical University of Vienna

Unknown

Epigenetics Based Diagnosis of Diabetes in Saliva and Blood Samples

Diabetes Mellitus, Type 2 | Prediabetic State | Ectopic Lipids | Epigenetics Based Modifications

Austria
Montefiore Medical Center
Albert Einstein College of Medicine

Terminated

Biomarkers, Neurodevelopment and Preterm Infants

Neurodevelopmental Disorder | Preterm | Epigenetic Changes

United States
Saglik Bilimleri Universitesi

Completed

Exercise on microRNA in Osteoarthritis

Depression | Quality of Life | Pain | Osteoarthritis, Knee | Epigenetic Disorder

Turkey
IRCCS Eugenio Medea
Università degli Studi di Brescia; Fondazione Istituto Neurologico Casimiro...

Completed

Early Parenting Intervention: Bio-behavioral Outcomes in Infants With Neurodevelopmental Disabilities (EPI-BOND)

Parent-Child Relations | Developmental Disability | Early Intervention | Epigenomics

Italy
University of Gaziantep

Completed

miRNA Biomarkers in Multiple Sclerosis

Multiple Sclerosis | Biomarker | miRNA | Epigenetic
University of Arkansas, Fayetteville

Unknown

Using Polar Unite Fitness Watch to Improve Cognition for T2DM Patients

Diabetes Mellitus, Type 2, Cognitive Dysfunction, Epigenetics, Exercise
University of Ljubljana, Faculty of Medicine
University Medical Centre Ljubljana; University Maribor; University Psychiatric...

Recruiting

Self-harm Behaviour Among the Most At-risk Adolescents (SH-MARA)

Non-Suicidal Self Injury | Self-harm | Personality Disorder, Borderline | Difference, Individual | Epigenetic Disorder | Change; Mental

Slovenia
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; Celgene; Stand Up To Cancer; Syndax Pharmaceuticals; Rhone-Poulenc... and other collaborators

Completed

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC. (NA_00084192)

Non-Small Cell Lung Cancer | Epigenetic Therapy

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity (EPSACO)

Biomarkers | Epigenetics | Oral Squamous Cell Carcinoma | DNA Methylation | Saliva | Maxillo-facial Surgery

France
Institute of Hematology & Blood Diseases Hospital

Recruiting

Chidamide Plus Azacitidine for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma

Peripheral T Cell Lymphoma | Epigenetic Repression

China
University of Lorraine

Recruiting

Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.

Quality of Life | Chronic Pain | Resilience, Psychological | Adverse Childhood Experiences | Chronic Stress | Attachment Styles | Epigenesis, Genetic

France
Hospital Clinico Universitario de Santiago
Hospital Arquitecto Marcide

Not yet recruiting

Nutritional Intervention-induced Weight Loss During the Oncological Treatment of Obesity-related Breast Cancer (NUTOBREST)

Obesity | Breast Cancer | Weight Change, Body | Epigenetic Disorder
Montefiore Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Early Childhood Obesity Programming by Intrauterine Growth Restriction

Childhood Obesity | Epigenetics

United States
University of Lorraine
Ligue contre le cancer, France

Recruiting

Adverse Childhood Experiences, Adaptation and Breast Cancer (CAPONE)

Quality of Life | Cancer, Breast | Resilience, Psychological | Adverse Childhood Experiences | Attachment Styles | Epigenesis, Genetic

France
University of Guadalajara
Hospital Central Militar

Recruiting

Prolonged Release Pirfenidone for Advanced Residual Liver Fibrosis (MINERVA).

Liver Cirrhosis | Hepatitis C, Chronic | Epigenetic Disorder

Mexico
Hadassah Medical Organization

Unknown

Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes

Gestational Diabetes | Epigenetic Changes | Pregestational Diabetes | Neurodevelopmental Outcome | IDM (Infant of Diabetic Mothers)

Israel
Hunan Cancer Hospital

Recruiting

Anti-PD-1 Antibody Combined With Peg-Asparaginase and Chidamide for the Early Stage of NK/T Cell Lymphoma

Chemotherapy Effect | NK/T-cell Lymphoma of Nasal Cavity | Immune Checkpoint Inhibitor | Epigenetic Disorder

China
Linkoeping University

Recruiting

Physiological Studies in Post-COVID-19 Syndrome, and the Association With DNA Methylation

Covid19 | Dyspnea | Lung Function Decreased | Cardiopulmonary Disease | Epigenetic Disorder

Sweden
Aragon Institute of Health Sciences

Completed

Epigenetics Modifications in Morbid Obesity and Obstructive Sleep Apnea Patients: The EPIMOOSA Study (EPIMOOSA)

Obstructive Sleep Apnea | Morbid Obesity | Epigenetic Disorder
University of Copenhagen
Rigshospitalet, Denmark

Recruiting

Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms (PANACEA)

Neoplasms | Quality of Life | Insulin Resistance | Exercise | Body Composition | Sarcopenia | Cachexia | Physical Functional Performance | Muscle, Skeletal | Patient Reported Outcome Measures | Gastrointestinal Microbiome | Metabolism | Caregivers | Adipose Tissue | Proteomics | Mitochondria | Lipidomics | Epigenomics

Denmark
Guangzhou Women and Children's Medical Center
University of Birmingham

Recruiting

Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study (PCOS-BIG)

Hyperandrogenism | Insulin Resistance | PCOS | Metabolic Disturbance | Epigenetics | Offspring, Adult | Endocrine Disorder

China

Clinical Trials on Epigenetics

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