Clinical Trials on Epilepsy, Tonic-Clonic

Total 34126 results

University Hospital, Basel, Switzerland

Completed

Bad News- Diagnosis: Epilepsy in Childhood (Badnews)

Epilepsy in Children

Switzerland
Hospices Civils de Lyon

Completed

Circulating microRNAs as Biomarkers of RESPIratory Dysfunction in Patients With Refractory epilePSY (MIRESPILEPSY)

Drug Resistant Epilepsy

France
Assiut University

Unknown

Nucleotide Protein -3 in Epileptic Children

Epilepsy in Children
All India Institute of Medical Sciences, New Delhi

Unknown

Comparison Between Efficacy of Daily and Intermittent Low Glycemic Index Therapy Diet

Drug Resistant Epilepsy

India
All India Institute of Medical Sciences, New Delhi

Unknown

Dietary Therapy In Epilepsy Treatment (DIET-Trial): A Randomised Non Inferiority Trial Comparing KD, MAD & LGIT for Drug Resistant Epilepsy (DIET)

Drug Resistant Epilepsy

India
Eisai Inc.

Completed

A Study to Investigate the Potential Pharmacokinetic Interaction of Perampanel With Oral Contraceptives in Healthy Female Subjects

Partial Onset Epilepsy

United Kingdom
Eisai Inc.

Completed

A Study to Demonstrate Bioequivalence Between 6 x 2 mg Tablets of Perampanel and a Single 12 mg Tablet of Perampanel in Healthy Subjects

Partial Onset Epilepsy

United Kingdom
Oslo University Hospital

Completed

Modified Atkins Diet in Children and Adolescents With Drug-resistant Epilepsy

Epilepsy

Norway
University Hospital, Geneva
University of Geneva, Switzerland

Not yet recruiting

Investigating Surprise Signals in the Anterior Insula

Healthy | Drug Resistant Epilepsy

Switzerland
Mayo Clinic

Recruiting

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Focal Epilepsy

United States
Aristotle University Of Thessaloniki

Recruiting

TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response (BIOEPI)

Focal Epilepsy

Greece
Eindhoven University of Technology
Clinical Trial Center Maastricht B.V.

Recruiting

Priming the Epileptic Brain: tVNS to Improve Efficacy of add-on AED in Patients With Focal Epilepsy (PREP)

Focal Epilepsy

Netherlands
University Hospital, Tours

Recruiting

Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy (ORACLE)

Focal Epilepsy

France
Mid-Atlantic Epilepsy and Sleep Center, LLC

Recruiting

Prospective Open-label Evaluation of Cenobamate Adjunctive Treatment of Adults With Refractory Focal Epilepsy

Focal Epilepsy

United States
Xenon Pharmaceuticals Inc.
Novotech Health Holdings Pte. Ltd.

Active, not recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy (X-TOLE)

Focal Epilepsy

Spain, United States, Ukraine, Canada, United Kingdom, Germany, Georgia, Italy, Moldova, Republic of
Dhaka Medical College

Enrolling by invitation

The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy

Focal Epilepsy

Bangladesh
Yang Xinwei

Active, not recruiting

Clinical Efficacy and Safety of Perampanel Monotherapy in the Treatment of Children With Focal Epilepsy

Focal Epilepsy

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice

Focal Epilepsy
Rennes University Hospital

Completed

Effects of Transcranial Direct Current Stimulation (TDCS) in Drug-resistant Partial Epilepsy (BRAINSTIM)

Epilepsy

France
GlaxoSmithKline

Withdrawn

Pharmacokinetic Study of Retigabine Extended Release (XR) Formulation in Healthy Adult Japanese and Caucasian Subjects

Epilepsy, Partial

Japan
Supernus Pharmaceuticals, Inc.

Completed

Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy

Partial Epilepsy

United States, Poland, Bulgaria, Romania, Canada, Russian Federation, Mexico, Croatia
Pavel Klein
H. Lundbeck A/S

Unknown

Clobazam Adjunctive Treatment of Adults With Refractory Focal Epilepsy

Epilepsy

United States
Central Hospital, Nancy, France
Institut National de la Santé Et de la Recherche Médicale, France; CHU de Reims and other collaborators

Completed

Localizing the Epileptogenic Zone With High Resolution Electroencephalography (EEG-HR)

Partial Epilepsy

France
Eisai Inc.

Completed

A Double-blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in Newly Diagnosed Partial Epilepsy

Epilepsy

Australia, France, Poland, Germany, Spain, India, Serbia, Greece, Korea, Republic of, Russian Federation, Taiwan, Hungary, Italy, Sweden, Denmark, Slovakia, United Kingdom, South Africa
Mayo Clinic

Completed

Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy

Epilepsy

United States
Cyberonics, Inc.

Terminated

Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients

Epilepsy | Partial Epilepsy

Canada, Spain, Belgium, France, Germany, Italy, Netherlands, Norway, Sweden, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy

Partial Epilepsy

United States
University Hospital, Strasbourg, France

Unknown

Genetic Basis of Idiopathic Focal Epilepsies With Cognitif Deficits

Epilepsy

France
State Budgetary Healthcare Institution, National...

Enrolling by invitation

Thermocoagulation in Drug Resistant Focal Epilepsy

Epilepsy | Epilepsies, Partial | Epilepsy Intractable | Seizures, Focal

Russian Federation
University of Alabama at Birmingham

Withdrawn

Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus

Refractory Epilepsy

United States
Eisai Inc.

Available

Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies

Epilepsies, Myoclonic | Drug Resistant Epilepsy
National Institute of Neurological Disorders and...

Recruiting

Investigating Epilepsy: Screening and Evaluation

Epilepsy | Seizures | Epilepsy, Temporal Lobe | Partial Epilepsy

United States
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Johns Hopkins University
Vitaflo International, Ltd

Completed

Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy

Epilepsy | Seizure | Catamenial Epilepsy | Medically Resistant Epilepsy | Medically Resistant Seizures

United States
National Institute of Neurological Disorders and...

Completed

Language and Emotional Function in Patients With Temporal Lobe Epilepsy

Epilepsy | Temporal Lobe

United States
Pfizer

Completed

Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.

Epilepsy | Epilepsy, Generalized | Seizures | Epilepsies, Partial | Epilepsy, Complex Partial

United States
National Taiwan University Hospital

Not yet recruiting

Electrical Neuromodulation for Focal Epilepsy

Epilepsy
Wayne State University
National Institutes of Health (NIH)

Recruiting

Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery

Focal Epilepsy

United States
University Hospital, Toulouse

Recruiting

Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy (StiMiC)

Epilepsy

France
National Institute of Neurological Disorders and...

Recruiting

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

Epilepsy

United States
UCB Pharma

Completed

A Study Of The Safety And Efficacy Of Levetiracetam (Keppra®) (Ucb L059) In Children With Epilepsy

Epilepsy, Partial
University Hospital, Toulouse
CerCo, CNRS Cerco UMR5549 CHU Purpan Toulouse France; DIXI Medical, Besançon...

Completed

Recording "Fast Ripples" Using Microelectrodes During Stereo-encephalography in Patients With Drug-resistant Partial Epilepsy (Epi-FaR)

Epilepsy

France
H. Lundbeck A/S

Terminated

A Study of Lu AG06466 in Participants With Treatment Resistant Focal Epilepsy

Focal Epilepsy

United States
Eisai Korea Inc.

Completed

Open-label, Multi-center Trial of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy

Epilepsy

Korea, Republic of
NYU Langone Health
The Epilepsy Study Consortium

Completed

The Human Epilepsy Project (HEP)

Focal Epilepsy

United States, Canada, Australia
Korea UCB Co., Ltd.

Completed

Levetiracetam Versus Oxcarbazepine as Monotherapy to Evaluate Efficacy and Safety in Subjects With Newly or Recently Diagnosed Partial Epilepsy (OPTIMAL)

Epilepsy

Korea, Republic of
Bial - Portela C S.A.

Completed

Study to Evaluate Pharmacokinetics and Tolerability of Multiple Doses of Eslicarbazepine Acetate and Oxcarbazepine

Partial Epilepsy

Belgium
UCB Pharma

Completed

Determine Effects of Adjunctive Levetiracetam on Sleep Architecture in Adults With Partial Onset Epilepsy.

Epilepsy, Partial
UCB Pharma

Completed

Trial to Evaluate the Safety and Efficacy of Keppra After Conversion to Mono-therapy in Subjects With Partial Epilepsy

Epilepsy

Clinical Trials on Epilepsy, Tonic-Clonic

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