Clinical Trials on Esophageal Adenocarcinoma (EAC) in Brazil

Total 292 results

University of Sao Paulo General Hospital

Unknown

Laparoscopy Heller Myotomy With Fundoplication Associated Versus Peroral Endoscopic Myotomy (POEM)

Dysphagia | Achalasia

Brazil
Federal University of São Paulo
Hospital State Public

Completed

Laparoscopic Nissen Fundoplication Comparing Division Versus Non-Division of Short Gastric Vessels

Gastroesophageal Reflux

Brazil
Fauze Maluf Filho

Terminated

Endoscopic Injection of Mitomycin C for the Treatment of Pharyngoesophageal Stenosis

Head and Neck Neoplasms | Esophageal Neoplasms | Deglutition Disorders | Esophageal Stenosis

Brazil
Universidade de Passo Fundo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients (NORGERD)

Gastroesophageal Reflux Disease

Brazil
Federal University of São Paulo

Unknown

Evaluation of Topical Mitomycin C as Adjuvant Drug to Esophageal Dilation in Children

Esophageal Stricture | Caustic Esophageal Stricture | Peptic Esophageal Stricture | Post-Surgical Esophageal Stricture

Brazil
University of Sao Paulo General Hospital

Completed

Evaluate the Intestinal Microbiome in Patients With Erosive Gastroesophageal Reflux Disease and in Asymptomatic Healthy Controls

Gastroesophageal Reflux Disease With Esophagitis

Brazil
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Esophageal Squamous Cell Carcinoma (ESCC) | Gastroesophageal Junction Carcinoma (GEJC) | Esophageal Adenocarcinoma (EAC)

China, Canada, United States, Argentina, Belgium, Brazil, Chile, Czechia, Denmark, Estonia, France, Germany, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Mexico, Peru, Philippines, Portugal, Romania, Russian Federation and more
Instituto do Cancer do Estado de São Paulo

Recruiting

Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus.

Esophageal Neoplasms | Dysphagia

Brazil
Federal University of São Paulo

Unknown

Swallowing Rehabilitation of Dysphagic Tracheostomized Patients Under Mechanical Ventilation at ICU

Dysphagia

Brazil
Eurofarma Laboratorios S.A.

Completed

A Study of Chemoradiation Associated With Nimotuzumab as the Treatment of Locally Advanced Esophageal Cancer (NICE)

Adenocarcinoma | Esophageal Cancer

Brazil
Federal University of Uberlandia

Completed

Phenotypic Characterization and Biomarkers Investigation for Eosinophilic Esophagitis in Pediatric Patients

Gastroesophageal Reflux | Eosinophilic Esophagitis

Brazil
Clinica Gastrobese

Completed

Clinico-functional Evaluation of GERD: Comparative Study of Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass

Gastroesophageal Reflux Disease | Morbid Obesity

Brazil
Hospital Moinhos de Vento

Recruiting

Deflating the Tracheostomy Tube Cuff and Time for Decannulation

Deglutition Disorders | Tracheostomy Complication

Brazil
Faculdade de Ciências Médicas da Santa Casa de...

Completed

Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis

Gastroesophageal Reflux Disease (GERD) | Chronic Laryngitis

Brazil
Federal University of São Paulo

Completed

A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices

Liver Disease

Brazil
Hospital Infantil Cândido Fontoura

Completed

Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children

Dyspepsia | Abdominal Pain | Gastroesophageal Reflux Disease | Malabsorption Syndrome

Brazil
Faculdade de Ciências Médicas da Santa Casa de...

Completed

Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis (EGFR)

Gastroesophageal Reflux Disease | Chronic Laryngitis

Brazil
Federal University of São Paulo

Completed

PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES?

CIRRHOSIS | ESOPHAGEAL VARICES

Brazil
Takeda

Completed

Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease (PAMES 0109)

GERD

Brazil
Boston Scientific Corporation

Completed

WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture (E7025)

Refractory Anastomotic Esophageal Strictures

Netherlands, Sweden, Brazil
Instituto do Cancer do Estado de São Paulo

Unknown

Intralesional Steroid Injection Versus Oral Prednisolone in Prevention of Esophageal Stricture

Esophageal Stenosis

Brazil
University of Sao Paulo
W.L.Gore & Associates; InCor Heart Institute

Terminated

Endoscopic Closure of Tracheoesophageal Fistulas With Occluder Device (TEFGoreHelex)

Acquired Tracheo-esophageal Fistula

Brazil
Clinica Gastrobese

Completed

Gastroesophageal Reflux Disease (GERD) Before and After Gastric Bypass

Gastroesophageal Reflux Disease | Morbid Obesity

Brazil
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Simvastatin Effect on Portal Hypertension

Liver Cirrhosis | Portal Hypertension | Esophageal Varices

Brazil
AstraZeneca

Completed

Non-interventional Study to Evaluate the Change in Symptoms Scores and Treatment Response After 4 Weeks of Proton-Pump Inhibitors (PPI) Treatment

Gastroesophageal Reflux

Romania
Tiago Biachi

Unknown

Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma (DESC)

Esophageal Squamous Cell Carcinoma

Brazil
Clinica Gastrobese

Terminated

Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP (RING)

Vomiting | Gastroesophageal Reflux Disease | Morbid Obesity

Brazil
Instituto do Cancer do Estado de São Paulo

Recruiting

Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections

Esophageal Neoplasms | Hyaluronic Acid | Endoscopic Mucosal Resection

Brazil
Federal University of Mato Grosso

Completed

Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine

Pulmonary Aspiration of Gastric Contents | Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics | Pulmonary Aspiration During Anaesthetic Induction

Brazil
Instituto do Cancer do Estado de São Paulo

Recruiting

Supercharged TRAM Evaluation in Cervical Esophagogastroplasty After Esophagectomy (Supercharged)

Esophagus Cancer | Carcinoma Esophagus

Brazil
University of Sao Paulo General Hospital

Unknown

Gastric Varices Treatment: Coil + Cyanoacrylate Versus Cyanoacrylate

Gastric Varices

Brazil
Barretos Cancer Hospital

Completed

Swallowing Intervention During Radiochemotherapy on Head and Neck Cancer (Swallowing-1)

Swallowing Disorders | Head Neck Cancer

Brazil
Instituto Nacional de Cancer, Brazil

Unknown

Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer (QUIMERA)

Esophageal Cancer | Induction Chemotherapy

Brazil
Eurofarma Laboratorios S.A.

Withdrawn

Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC

Gastroesophageal Reflux Disease

Brazil
Fortaleza University

Completed

Functional Endoscopic Evaluation of Swallowing

Cerebral Palsy | Dysphagia

Brazil
Jazz Pharmaceuticals
BeiGene, Ltd.

Recruiting

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers (HERIZON-GEA-01)

Gastroesophageal Adenocarcinoma | Esophageal Adenocarcinoma | Gastric Neoplasms

Korea, Republic of, Belgium, Japan, China, Netherlands, Spain, Germany, United Kingdom, Malaysia, Taiwan, Portugal, France, Italy, Australia, Turkey, Thailand, Argentina, Mexico, Ireland, Estonia, Serbia, Romania, Canada, Poland, Brazil, ... and more
Pfizer

Terminated

Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

Brazil, Germany, Korea, Republic of, Belgium, Spain, Slovakia, France
Daiichi Sankyo
AstraZeneca

Recruiting

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Gastroesophageal Junction Adenocarcinoma | Gastric Cancer, Adenocarcinoma

Hong Kong, Korea, Republic of, France, United Kingdom, Spain, China, Ireland, Brazil, Japan, Singapore, Belgium, Israel, Russian Federation, Argentina, Chile, Hungary, Poland, Portugal, Taiwan, Turkey, Ukraine, Germany, Romania, Italy
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Active, not recruiting

Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer (CheckMate649)

Gastric Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Cancer

United States, Argentina, Australia, Brazil, Canada, Chile, China, Colombia, Czechia, France, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Peru, Poland, Portugal, Romania, Russian Federation, Si... and more
Eurofarma Laboratorios S.A.

Withdrawn

Clinical Study, Multicenter, Randomized With 2 Arms of Pantoprazole + Domperidone and Pantoprazole Isolated at the Gastroesophageal Reflux Disease (PANDA)

Gastroesophageal Reflux Disease

Brazil
Centro Universitário de Anapolis
Centro Universitário Fundação Assis Gurgacz

Recruiting

Chewing, Swallowing and Orofacial Motricity in Severe Obese

Swallowing Disorder | Mastication Disorder | Orofacial Dyskinesia

Brazil
Hospital Geral de Fortaleza

Completed

Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke

Stroke, Ischemic | Dysphagia, Oropharyngeal

Brazil
Fauze Maluf Filho

Completed

Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy

Head and Neck Neoplasms | Esophageal Neoplasms | Colorectal Polyps | Barrett Esophagus | Pancreatic Duct Stricture | Gastric Antrectomy Partial | Biliary Duct Stricture

Brazil
Amgen
Zai Lab (China only)

Recruiting

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-101)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Canada, Japan, United States, Korea, Republic of, China, Italy, Australia, Sweden, Spain, Taiwan, France, Belgium, Denmark, Thailand, Turkey, Czechia, Bulgaria, Brazil, Norway, Mexico, Poland, Estonia, Israel, Greece, Romania, Chile, Peru, Po... and more
Amgen

Recruiting

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer (FORTITUDE-102)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of, United States, Israel, Italy, Spain, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Japan, Taiwan, China, Belgium, Poland, Thailand, Czechia, Singapore, Hungary, Argentina, Brazil, Romania, Portuga... and more
Federal University of Bahia

Completed

Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease

Parkinson Disease | Dysphagia

Brazil
University of Sao Paulo General Hospital
Circa Scientific

Completed

Randomized Study on the Effect of Oesophageal Temperature on the Incidence of Esophageal Lesions After AF Ablation

Atrial Fibrillation | Cardiac Arrhythmias | Esophageal Ulcer

Brazil
Janssen Research & Development, LLC
Eisai Inc.

Completed

A Study of Single and Multiple Doses of Rabeprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Months Old, Inclusive

Gastroesophageal Reflux Disease (GERD)

United States, Poland, United Kingdom, Belgium, Brazil
Instituto do Cancer do Estado de São Paulo

Unknown

A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment.

Rectal Cancer

Brazil
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

Gastric Neoplasms | Gastroesophageal Junction Adenocarcinoma

United States, Australia, Brazil, Chile, China, France, Germany, Guatemala, Ireland, Israel, Italy, Japan, Korea, Republic of, New Zealand, Poland, Russian Federation, Spain, Turkey, Ukraine, United Kingdom

Clinical Trials on Esophageal Adenocarcinoma (EAC) in Brazil

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