Clinical Trials on Estrogen Receptor Negative

Total 3810 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer Survivors (PACT)

Sedentary Lifestyle | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC... and other conditions

United States
Syndax Pharmaceuticals

Completed

Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer (ENCORE110)

Breast Cancer | Lung Cancer | Non Small Cell Lung Cancer (NSCLC) | Estrogen Receptor Breast Cancer

United States
University of Colorado, Denver
National Institute on Aging (NIA)

Not yet recruiting

Cardiometabolic Consequences of the Loss of Ovarian Function (LILAC)

Menopause | Aging | Adiposity | Estrogen Deficiency

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
AbbVie

Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Hepatocellular Carcinoma | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Biliary Tract Cancers | Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer | Head and Neck Squamous-Cell Carcinoma

United States, Israel, Japan, Puerto Rico
National Institute of Mental Health (NIMH)

Completed

Evaluation of Two Radioactive Chemicals to Image mGluR5 Receptors in Brain

mGluR5 Receptors

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

Adult Solid Tumor | HER2-positive Breast Cancer | Recurrent Melanoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Stage IV Ovarian Germ Cell Tumor | Recurrent Breast Cancer | Estrogen Receptor-negative Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-negative... and other conditions

United States
Puma Biotechnology, Inc.

Terminated

HER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for Enrollment Into Clinical Research Studies of Neratinib

Metastatic Cervical Cancer | Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer

Spain, Israel, United States, Serbia, France, Ireland, Italy
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Terminated

Dopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine Users

Cognitive Function | Methamphetamine Abuse | Dopamine D2/3 Receptor Availability

United States
Mackay Memorial Hospital

Not yet recruiting

Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause

Menopause | Vaginal Atrophy | Platelet-rich Plasma | Estrogen Replacement Therapy
Assiut University

Not yet recruiting

Safety of Oral Thrombopoietin Receptor Agonist in Pediatric Chronic ITP

Thrombopoietin Receptor Agonist
AstraZeneca

Completed

AZD5069 Neutrophil Function Study

Chemokine Receptor 2 (CXCR2) Antagonist

United Kingdom
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Mobile Health for Adherence in Breast Cancer Patients

Breast Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Daiichi Sankyo Co., Ltd.
AstraZeneca; Daiichi Sankyo, Inc.

Recruiting

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Hormone Receptor Positive Breast Cancer

United States, Japan
Northwestern University
National Cancer Institute (NCI)

Completed

4-Hydroxytamoxifen or Tamoxifen Citrate in Treating Women With Newly Diagnosed Ductal Breast Carcinoma in Situ

Estrogen Receptor-positive Breast Cancer | Ductal Breast Carcinoma in Situ

United States
University of Catanzaro

Completed

Estrogen Receptors and Chronic Venous Disease (ERCVD)

Varicose Veins | Estrogen Excess
Peregrine Pharmaceuticals

Withdrawn

A Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Triple-Negative Breast Cancer | Triple-Negative Breast Neoplasm | ER-Negative PR-Negative HER2-Negative Breast Neoplasms | ER-Negative PR-Negative HER2-Negative Breast Cancer
Instituto Bernabeu

Not yet recruiting

TRAP Study: Testosterone for Androgen Receptor Polymorphism (TRAP)

Fertility Disorders

Spain
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Astellas Pharma US, Inc.

Active, not recruiting

Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers

Salivary Cancer

United States
Pennington Biomedical Research Center
Louisiana Clinical and Translational Science Center

Terminated

The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause (RESUME)

Adiposity | Menopause Surgical | Estrogen Deficiency

United States
University Hospitals Cleveland Medical Center

Withdrawn

Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery

Menopause | Surgery | Pelvic Floor Disorders | Estrogen

United States
University of Eastern Finland

Completed

The Effect of a High-dose Oral Vitamin D3 Bolus on Serum 25(OH)D3 and Vitamin D Receptor Target Gene Expression (VitDbol)

Vitamin D Receptor Target Gene Expression | Serum 25(OH)D Concentration

Finland
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Impact of Gonadotrophin REceptor Polimorphisms on the Relationship Between Serum AMH and Ovarian Response (GREPAMOR)

antimüllerian Hormone and Gonadotrophin Receptor Polymorphism as Predictors of Ovarian Response

Spain
Yale University
VA Office of Research and Development

Completed

The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects (GuaKet)

NMDA Receptor Function

United States
Astellas Pharma Global Development, Inc.

Withdrawn

A Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid Tumors

Solid Tumors | Epidermal Growth Factor Receptor (EGFR) Mutations
Northwestern University
National Cancer Institute (NCI); BHR Pharma, LLC

Recruiting

Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast

Estrogen Receptor Positive | Ductal Breast Carcinoma In Situ

United States
The Netherlands Cancer Institute
Astellas Pharma Inc

Completed

Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation (DARANA)

Prostate Cancer | Androgen Receptor Abnormal | DNA
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Estrogen Receptor Positive | Postmenopausal

United States
University of Southern California

Terminated

The Effect of Mifepristone on the Expression of Cervical Prostaglandin EP3 Receptors (EP3)

Pregnancy | Cervical Prostaglandin EP3 Receptors

United States
M.D. Anderson Cancer Center

Not yet recruiting

Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)

Hormone Receptor-positive Human Epidermal Growth Factor 2-negative | Metastatic Invasive LObular Carcinoma

United States
University of California, San Francisco
Amgen

Active, not recruiting

T-VEC With Chemotherapy or Endocrine Therapy in Treating Participants With HER2- Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
Xiao Wang

Recruiting

Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen

Estrogen | Postmenopausal Depression

China
Medical University of Bialystok
American Medical Holdings Inc., Staten Island, NY 10314 USA; School of Pharmacy...

Completed

Association Between Vitamin D Receptor Polymorphism and Serum Vitamin D Levels in Children With Low-Energy Fractures

Vitamin D Receptor Defect

Poland
Bispebjerg Hospital
Institute of Sports Medicine, Copenhagen

Completed

Supplementary Intake of Vitamin D During 12 Weeks Strength Training in Younger and Older People

Muscle Strength | Tendon Elasticity | Muscle CSA | Tendon CSA | VDR Receptor

Denmark
Dana-Farber Cancer Institute
Genentech, Inc.

Recruiting

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Breast Cancer | Invasive Carcinoma of the Breast | Node Negative Breast Cancer | Micrometastasis Breast Cancer

United States
National Cancer Institute (NCI)

Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Emory University
National Cancer Institute (NCI)

Recruiting

A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Taipei Veterans General Hospital, Taiwan
National Yang Ming University

Unknown

Clinical Study of YQ1 Plus Cisplatin-based Chemotherapy in Advanced NSCLC EGFR Wild Type

Epithelial Growth Factor Receptor Negative Non-small Cell Lung Cancer
Janssen Research & Development, LLC

Completed

A Study to Identify Participants With Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations

Urothelial Cancer | Receptors, Fibroblast Growth Factor

United States, Italy, Belgium, United Kingdom, Japan, Turkey, Brazil, Ukraine, Spain, Russian Federation, Israel, France, Germany, Argentina
Beijing Tongren Hospital
Peking Union Medical College Hospital; Beijing Tiantan Hospital; Xuanwu Hospital... and other collaborators

Unknown

Multicenter and Prospective Clinical Registry Study of Anti-N-methyl-D-aspartate Receptor Encephalitis in China

Anti-NMDA Receptor Enphalitis
National Cancer Institute (NCI)

Withdrawn

Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditions
University of Eastern Finland
DSM Nutritional Products, Inc.

Completed

Efficiency of Vitamin D3 and 25-hydroxyvitamin D3 on Transcriptomic Changes of Low Vitamin D Responders (VitDHiD)

Vitamin D Receptor Target Gene Expression | Serum 25(OH)D Concentration

Finland
University of Sao Paulo General Hospital

Not yet recruiting

Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME) (ESTIME)

Menopause | Testosterone Deficiency | Estrogen Deficiency
Lei Li

Unknown

Immune Repertoire of Ovarian HGSC

Ovarian High Grade Serous Carcinoma | Immune Repertoire | T Lymphocyte Receptor | B Lymphocyte Receptor

China
AstraZeneca

Completed

Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors

Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor

United Kingdom, United States
University of Nicosia

Not yet recruiting

The Effect of Androgen Receptor Polymorphism on Endometrial Cancer (AREC)

Endometrial Disorder | Androgen Receptor Abnormal
Hadassah Medical Organization

Completed

A Study to Examine the Effect of Reconval K1 Cream to Prevent Skin Toxicity From EGFRI (EGFRI)

Rash Due to Epidermal Growth Factor Receptor Inhibitors
Peking Union Medical College Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab and AI in the First-line Treatment of HER2 Positive/ HR Positive MBC (Pyrotinib)

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor
National Cancer Institute (NCI)

Not yet recruiting

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Estrogen Receptor-Positive Breast Carcinoma

United States
Vyne Therapeutics Inc.

Completed

Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients

Rash Due to Epidermal Growth Factor Receptor Inhibitors

Israel

Clinical Trials on Estrogen Receptor Negative

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