Clinical Trials on Exstrophie-Epispadien-Komplex

Total 1596 results

Istituto Clinico Humanitas

Completed

Regorafenib in Patients With Metastatic Solid Tumors Who Have Progressed After Standard Therapy (RESOUND)

Melanoma | Sarcoma | Ovarian Cancer | Thymic Carcinoma | Pancreas Cancer | Thymoma Type B3 | Thymoma Type B2

Italy
Entasis Therapeutics

Completed

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex (ATTACK)

Bacteremia | Ventilator-associated Bacterial Pneumonia | Acinetobacter Baumannii-calcoaceticus Complex | Hospital-acquired Bacterial Pneumonia | Colistin Resistant ABC

United States, Belarus, Brazil, China, Greece, Hungary, India, Israel, Korea, Republic of, Lithuania, Mexico, Peru, Puerto Rico, Russian Federation, Taiwan, Thailand, Turkey
University of Pennsylvania

Completed

Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)

HIV Dementia

United States
University of Hawaii
Oregon Health and Science University

Completed

Ferumoxytol-enhanced Brain MRI in HIV-associated Neurocognitive Disorders

HIV Dementia

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases

Myelodysplastic Syndromes | Leukemia | Thymic Carcinoma | Graft Versus Host Disease

United States
Fudan University

Recruiting

Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma

Kidney Cancer | Renal Cell Carcinoma | Renal Clear Cell Carcinoma

China
Centre Leon Berard

Recruiting

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS) (BFR-ESS)

Low Grade Endometrial Stromal Sarcoma

France
Marinus Pharmaceuticals

Active, not recruiting

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy (TrustTSC)

Tuberous Sclerosis Complex

United States, Spain, United Kingdom, Israel, Italy, Germany, France, Canada
Vanderbilt-Ingram Cancer Center
Bristol-Myers Squibb; Xcovery Holdings, Inc.

Active, not recruiting

Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors

Thymic Carcinoma | Non-small Cell Lung Cancer | Small-Cell Lung Cancer | Refractory Thoracic Tumors

United States
Translational Genomics Research Institute
United States Department of Defense

Completed

Studies in Patients With Tuberous Sclerosis Complex

Tuberous Sclerosis Complex

United States
Australia New Zealand Gynaecological Oncology Group
BeiGene

Withdrawn

Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy (PRECISE)

Ovarian Cancer | Carcinosarcoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

Genetics of Wilms' Tumor and/or the Associated Conditions of Aniridia, Hemihypertrophy, and Genitourinary Anomalies

Wilms' Tumor | Aniridia

United States
Nicholas M Mohr

Completed

Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation

Emergencies | Fluid Loss | Symptom Complex, Triple

United States
Children's Hospital Medical Center, Cincinnati
Novartis

Completed

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

Epilepsy | Tuberous Sclerosis Complex

United States
Children's Cancer and Leukaemia Group

Unknown

Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Kidney Cancer

United Kingdom, Ireland
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis

Lymphoma | Leukemia | Chronic Myeloproliferative Disorders | Precancerous Condition | Nonneoplastic Condition

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

Brain and Central Nervous System Tumors

United States
University of Rochester

Completed

Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia

HIV Infections | Cognitive Disorders

United States
Katarzyna Kotulska

Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex (RaRE-TS)

Tuberous Sclerosis Complex

Poland
James Cleary, MD, PhD
Lustgarten Foundation; Arcus Biosciences, Inc.

Recruiting

Switch Maintenance in Pancreatic

Pancreatic Cancer | Adenocarcinoma of the Pancreas | Squamous Cell Carcinoma of Pancreas | Adenosquamous Carcinoma of the Pancreas

United States
Darcy Krueger

Recruiting

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study (TSC-STEPS)

Epilepsy | Tuberous Sclerosis Complex

United States
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

A Randomized Multicenter Study for Isolated Skin Vasculitis (ARAMIS)

IgA Vasculitis | Henoch-Schönlein Purpura | Cutaneous Polyarteritis Nodosa | Primary Cutaneous Vasculitis

United States, Canada, Japan
Marinus Pharmaceuticals

Enrolling by invitation

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Tuberous Sclerosis Complex

United States, Spain, United Kingdom, China, Italy, France, Israel, Germany, Canada, Australia
University of Alabama, Tuscaloosa
UAB Resource Centers for Minority Aging Research (RCMAR)

Completed

Exploring Racial Disparities in Sleep Health and Neurocognitive Function

HIV Dementia

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Stand Up To Cancer; Iovance Biotherapeutics, Inc.; Prometheus...

Completed

Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Adenocarcinomas | Squamous Cell Carcinoma | Advanced NSCLC | Metastatic Non-small Cell Lung Cancer | Adenosquamous Carcinoma

United States
Martina Bebin
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex

Tuberous Sclerosis Complex

United States
University Hospital, Basel, Switzerland

Withdrawn

Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC) (EAOC)

Endometriosis | Endometrioid Carcinoma | Clear Cell Carcinoma
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
UBP Greater China (Shanghai) Co., Ltd

Not yet recruiting

UB-621, a New Type of Anti-herpes Simplex Virus (HSV) Monoclonal Antibody for the Use in the Treatment of Adult Recurrent HSV-2 Infections of the Genitals

Recurrent Genital Herpes
Nobelpharma

Completed

NPC-06 to Pain Associated With Acute Herpes Zoster

Acute Pain in Herpes Zoster

Japan
Heidelberg ImmunoTherapeutics GmbH

Completed

Monoclonal Antibody Therapy Against Chronic Herpes Simplex Virus 2 Infection (MATCH-2)

Herpes Genitalis

Germany
Nobelpharma

Terminated

NPC-06 to Acute Pain in Herpes Zoster

Acute Pain in Herpes Zoster

Japan
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011)

Herpes Zoster
GlaxoSmithKline

Completed

Study to Assess the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) When Co-administered With GSK Biologicals' Diphtheria, Tetanus and Pertussis Vaccine (Boostrix®) in Adults Aged 50 Years and Older

Herpes Zoster

United States
University of Pittsburgh

Completed

Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study (MASH)

Bacterial Vaginosis

United States
Topical Remedy
Benu BioPharma, LLC

Completed

Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores

Recurrent Herpes Labialis

United States
French National Agency for Research on AIDS and...

Terminated

Effect of Male Circumcision on HIV Incidence (ANRS 1265)

HIV Infections | Herpes Genitalis | Venereal Diseases

South Africa
Astellas Pharma Europe Ltd.

Completed

Study to Evaluate the Safety and Pharmacokinetics of Single Doses of ASP2151 in Healthy Male Subjects and the Effects of Food

Herpes Zoster | Herpes Genitalis

France
Uppsala University

Unknown

Botulinumtoxin A Treatment in Epidermolysis Bullosa Simplex and Pachyonychia Congenita

Epidermolysis Bullosa Simplex

Sweden
InMed Pharmaceuticals Inc.

Completed

INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa

Epidermolysis Bullosa Dystrophica | Epidermolysis Bullosa Simplex | Epidermolysis Bullosa, Junctional | Kindler Syndrome

France, Germany, Greece, Israel, Italy
Kiniksa Pharmaceuticals, Ltd.

Completed

A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases

Plaque Psoriasis | Chronic Idiopathic Urticaria | Lichen Planus | Lichen Simplex Chronicus | Chronic Idiopathic Pruritus

United States
Northwestern University
Bausch & Lomb Incorporated

Terminated

Comparison of Topical 0.15% Gancyclovir Gel Versus 0.3% Hypromellose Gel for the Treatment of Herpes Zoster Keratitis

Herpes Zoster Keratitis

United States
University of Washington
GlaxoSmithKline

Completed

Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV

HIV Infection | Genital Herpes

United States
University of California, San Francisco
Pfizer

Terminated

Study to Find Out if Therapy With the Drug Pregabalin Relieves Pain During Shingles Compared With Placebo

Herpes Zoster | Postherpetic Neuralgia

United States
French National Agency for Research on AIDS and...

Completed

Anti-Herpetic Treatment of Genital Ulcer : Effect on HIV & Herpes Shedding (ANRS 1212)

Ulcer | Herpes Genitalis

Central African Republic, Ghana
Joyce Teng

Recruiting

Computational Drug Repurposing for All EBS Cases

Healthy | Epidermolysis Bullosa | Genetic Skin Disease | Epidermolysis Bullosa Dystrophica | Epidermolysis Bullosa Simplex | Epidermolysis Bullosa, Junctional

United States
OrienGene Biotechnology Ltd.

Unknown

A Phase I-c Study of Recombinant GM-CSF Herpes Simplex Virus to TreatⅣ M1c

Melanoma

China
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Acyclovir Therapy for Genital Herpes Ulcers in HIV Negative African Women

Ulcers of Female Genital Organs

Zambia
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

GUD Clinical and Virologic Response to Acyclovir in HIV Negative African Women (PK/GUD)

Genital Herpes

South Africa, Zambia
Glaxo Wellcome

Completed

A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients

HIV Infections | Herpes Simplex

United States

Clinical Trials on Exstrophie-Epispadien-Komplex

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Saint Lucia

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Rare Diseases

Drug Interventions

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