Clinical Trials on Eye Disease, Hereditary in Canada

Total 25104 results

Sunnybrook Health Sciences Centre
Allergan; Unity Health Toronto

Unknown

A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes

Macular Edema | Epiretinal Membrane

Canada
Yves Sauve
Canadian Institutes of Health Research (CIHR)

Terminated

Omega 6:Omega 3 Ratio and Progression of Age-related Macular Degeneration (AMD).

Age-related Macular Degeneration

Canada
Allergan

Completed

A Study of LUMIGAN® RC in the Clinical Setting

Ocular Hypertension | Glaucoma, Primary Open Angle

Canada
CSL Behring

Completed

Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks

Hereditary Angioedema

Bulgaria, United States, Poland, Spain, Hungary, United Kingdom, Russian Federation, Macedonia, The Former Yugoslav Republic of, Argentina, Australia, Canada, Czech Republic, Israel, Romania, Sweden
McMaster University

Active, not recruiting

Mean Visual Acuity Changes Following Five Injections of Aflibercept

Diabetic Macular Edema

Canada
Iantech, Inc

Unknown

A Study to Assess the Clinical Outcomes of Surgical Phaco Segmentation Techniques in Patients Undergoing Cataract Surgery

Cataract

Panama
McMaster Children's Hospital

Unknown

Introduction of Microsystems in a Level 3 Neonatal Intensive Care Unit

Lung Diseases | Stress, Psychological | Inflammatory Bowel Diseases | Neurodevelopmental Disorders | Eye Manifestations | Infant Nutrition Disorders

Canada
Shire

Completed

Long-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE

Hereditary Angioedema (HAE)

United States, United Kingdom, Germany, Canada, Italy, Jordan, Puerto Rico
Allergan

Completed

A Retrospective Chart Review of OZURDEX® in Patients With Macular Edema

Macular Edema

Canada
Alcon Research

Completed

Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Intervention

Sjogren's Syndrome

Canada
CHU de Quebec-Universite Laval

Terminated

Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Canada
Bausch & Lomb Incorporated

Completed

Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction

Cataract

Canada
Bayer
Regeneron Pharmaceuticals

Completed

To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada. (PEGASUS)

Wet Macular Degeneration

Canada
Michel Giunta
Bayer

Active, not recruiting

Treat and Extend Analysis Trial With Aflibercept in Wet-AMD

Wet Age-related Macular Degeneration

Canada
Maisonneuve-Rosemont Hospital
Novartis; Foundation Fighting Blindness; Fonds de recherche en ophtalmologie... and other collaborators

Completed

Omega-3 Supplementation and Vitreal VEGF Levels in Wet-AMD

Exudative Age Related Macular Degeneration

Canada
CIBA VISION
University of Waterloo

Completed

Fitting Children With Contact Lenses (COPPER)

Refractive Error

Canada
Lawson Health Research Institute

Completed

Intravitreal Injection Anesthesia - Comparison of Different Topical Agents

Age-Related Macular Degeneration (AMD)

Canada
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A)

Usher Syndrome, Type 2A | Retinitis Pigmentosa 39

United States, Canada, France, Germany, Netherlands, United Kingdom
CSL Behring

Completed

A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

Hereditary Angioedema Types I and II

United States, Spain, Australia, Canada, Czechia, Hungary, Israel, Italy, Romania, United Kingdom
Queen's University

Completed

Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery (PNK)

Macular Edema

Canada
Mount Sinai Hospital, Canada

Completed

Monovision for the Treatment of Diplopia

Strabismic Deviation

Canada
Astria Therapeutics, Inc.

Recruiting

A Study of STAR-0215 in Participants With Hereditary Angioedema

Hereditary Angioedema

United States, United Kingdom, Canada, Germany, Bulgaria, Czechia
Coopervision, Inc.
CORE

Completed

Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses

Presbyopia

United States, Canada
AHS Cancer Control Alberta

Completed

Study of AntiCTLA4 in Patients With Unresectable or Metastatic Uveal Melanoma

Uveal Melanoma

Canada
Coopervision, Inc.
CORE

Completed

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

Astigmatism

United States, Canada
Coopervision, Inc.
CORE

Completed

Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses.

Myopia

United States, Canada
Unity Health Toronto

Completed

Predictors of Treatment Response to Aflibercept and Aqueous Cytokine Levels in Diabetic Macular Edema

Diabetic Macular Edema

Canada
Lawson Health Research Institute

Unknown

Automatic Self Transcending Meditation (ASTM) Versus Usual Care in Patients With Glaucoma

Depression | Quality of Life | Glaucoma | Anxiety

Canada
Maisonneuve-Rosemont Hospital
Bayer

Unknown

Effect of Aflibercept (Eylea®) in the Management of Bevacizumab (Avastin®) Resistant Diabetic Macular Edema (Eylea)

Diabetic Macular Edema

Canada
Unity Health Toronto

Completed

Cytokine Levels in Patients With Persistent Diabetic Macular Edema Treated With Triamcinolone Acetonide

Diabetic Macular Edema

Canada
North Toronto Eye Care Laser and Eye Specialists
Allergan

Terminated

Combination OZURDEX® & LUCENTIS® vs. OZURDEX® Monotherapy in Incomplete-Responders With Diabetic Macular Edema (COLLIDE)

Diabetic Macular Edema

Canada
CHU de Quebec-Universite Laval
Pfizer; Canadian Glaucoma Clinical Research Council

Completed

Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma (SLT)

Glaucoma | Inflammatory Response

Canada
Neuracle Genetics, Inc
ORA, Inc.

Recruiting

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

Age-Related Macular Degeneration

Canada
Coopervision, Inc.

Completed

Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses

Myopia

Canada
Coopervision, Inc.

Completed

Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses

Myopia

Canada
DBYAN Medicine Professional Corporation
Allergan

Completed

A Investigator Masked Parallel Comparison of Tolerability of Combigan and Cosopt (CICOM1010)

Ocular Hypertension | Open Angle Glaucoma

Canada
Novartis Pharmaceuticals

Completed

The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada

Cryopyrin Associated Periodic Syndrome

Canada
Unity Health Toronto

Recruiting

Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria

Rhegmatogenous Retinal Detachment

Canada
Lawson Health Research Institute
Novartis Pharmaceuticals

Completed

Lucentis to Treat Pigment Epithelial Detachment

Pigment Epithelial Detachment

Canada
Shire

Completed

Observational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioedema

Hereditary Angioedema (HAE)

United States
CSL Behring
Chiltern International Inc.

Completed

Patient Registry Study of Berinert® in Normal Clinical Practice

Includes: Hereditary Angioedema

United States, Denmark, Germany, Switzerland
KalVista Pharmaceuticals, Ltd.

Terminated

A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (KVD824-201)

Angioedema, Hereditary, Types I and II

United States, Czechia, Germany, Hungary, Italy, North Macedonia, United Kingdom, Australia, Bulgaria, Canada, France, New Zealand, Puerto Rico
Unity Health Toronto

Completed

Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment

Rhegmatogenous Retinal Detachment

Canada
Mati Therapeutics Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of the QLT Proprietary Olopatadine-PPDS in Subjects With Seasonal Allergic Conjunctivitis to Ragweed in an Environmental Exposure Chamber Model.

Seasonal Allergic Conjunctivitis to Ragweed

Canada
Sunnybrook Health Sciences Centre

Recruiting

Pneumatic Retinopexy for Primary Rhegmatogenous Retinal Detachment: To Steamroll or Not

Rhegmatogenous Retinal Detachment

Canada
Sandoz

Completed

Study of Loteprednol Etabonate in Adults Undergoing Bilateral Cataract Surgery

Inflammation Following Ocular Surgery

Canada
PulseMedica

Recruiting

Imaging of Vitreous Opacities in Human Eyes

Floaters | Vitreous Opacities

Panama
Coopervision, Inc.

Completed

Multicenter Dispensing Study of Biofinity Lenses in Extended Range

Myopia | Hyperopia

United States, Canada
University of Calgary
Muscular Dystrophy Canada

Enrolling by invitation

Expiratory Muscle Strength Training (EMST) in Neuromuscular Disorders

Muscular Dystrophies | Oculopharyngeal Muscular Dystrophy | Myopathy; Hereditary

Canada
University of Calgary

Recruiting

High-Dose Vitamin D Induction in Optic Neuritis (VitaDON2)

Optic Neuritis

Canada

Clinical Trials on Eye Disease, Hereditary in Canada

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