Clinical Trials on Fetal Hydrops in United States

Total 623 results

University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Hyper- and Hypokalemic Periodic Paralysis Study (HYP-HOP)

Hyperkalemic Periodic Paralysis | Hypokalemic Periodic Paralysis

United States, Italy, United Kingdom
Imperial College London
Imperial College Healthcare NHS Trust

Unknown

The FLIP-1 Study: Vaginal Lactobacillus Supplementation in Women at High Risk of Preterm Birth

Preterm Birth | Preterm Labor | Preterm Premature Rupture of Membrane | Cervical Incompetence | Miscarriage in Second Trimester | Miscarriage in Third Trimester

United Kingdom
Yale University
Wilson Disease Association

Recruiting

Natural History of Wilson Disease

Wilson Disease

United States, Germany, United Kingdom
Loma Linda University

Withdrawn

Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities

Intracranial Hemorrhages | Respiratory Distress Syndrome, Newborn | Hypoxic-Ischemic Encephalopathy | Perinatal Death | Neonatal Seizure | Meconium Aspiration Syndrome | Neonatal Hypotension

United States
Yale University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Calcitonin for Treating X-linked Hypophosphatemia

Hypophosphatemic Rickets, X Linked Dominant

United States
Cyprium Therapeutics, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency

Menkes Disease | Occipital Horn Syndrome | Unexplained Copper Deficiency

United States
Children's Mercy Hospital Kansas City

Completed

Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets

Hypophosphatemic Rickets, X-Linked Dominant

United States
King's College Hospital NHS Trust
King's College London

Completed

Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy (RIFSYS)

Liver Cirrhosis | Hepatoencephalopathy, Early Fatal Progressive

United Kingdom
National Institute of Diabetes and Digestive and...

Recruiting

Natural History Study of Parathyroid Disorders

Primary Hyperparathyroidism | Pseudohypoparathyroidism | Parathyroid Cancer | Inheritable Bone Diseases | Multiple Endocrine Neoplasia, Type 1

United States
Yale University

Completed

Examining the Effect of Burosumab on Muscle Function

X-linked Hypophosphatemia

United States
Yale University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets

Hyperparathyroidism | Hypophosphatemia, Familial

United States
Queen Mary University of London

Completed

ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes (ESTEEM)

Obesity | Insulin Resistance | Gestational Diabetes | High Blood Pressure | Pre-eclampsia | Stillbirth | Small for Gestational Age | Raised Lipids

United Kingdom
Indiana University

Recruiting

Indiana University Gastrointestinal Motility Diagnosis Registry

Constipation | Eosinophilic Esophagitis | Gastroparesis | Gastroesophageal Reflux Disease (GERD) | Fecal Incontinence | Small Intestinal Bacterial Overgrowth | Irritable Bowel Syndrome (IBS) | Functional Vomiting | Chronic Intestinal Pseudo-obstruction

United States
Massachusetts General Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Calcitriol Monotherapy for X-Linked Hypophosphatemia

X-linked Hypophosphatemia | Hypophosphatemic Rickets | Hypophosphatemic Rickets, X-Linked Dominant

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study (PPHN)

Persistent Fetal Circulation Syndrome | Infant, Small for Gestational Age | Persistent Pulmonary Hypertension of Newborn | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Alexion Pharmaceuticals

Completed

Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients

Wilson Disease

United States, Germany, Austria, Poland, United Kingdom
Alexion

Completed

The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment

Wilson Disease

United States, Germany, Austria, Poland, United Kingdom
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of KRN23 in X-linked Hypophosphatemia

X-linked Hypophosphatemia

United States
Novartis Pharmaceuticals

Completed

Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia Patients

Anemia | Hemosiderosis

United States, Germany, Belgium, United Kingdom, Italy, Canada, France
Novartis Pharmaceuticals

Completed

Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload (CORDELIA)

Transfusional Hemosiderosis | Transfusional Iron Overload

Taiwan, Turkey, Egypt, United Kingdom, Thailand, Canada, China, Italy, Cyprus, Lebanon, United Arab Emirates
Wake Forest University Health Sciences

Completed

FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP) (GAP)

Hypophosphatemia | X-linked Hypophosphatemia | Left Ventricular Hypertrophy | Renin-angiotensin System

United States
Vivet Therapeutics SAS

Recruiting

A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease (GATEWAY)

Wilson's Disease

United States, Denmark, Germany, United Kingdom
Ultragenyx Pharmaceutical Inc

Completed

Clinical Evaluation and Assessment of Instruments and Biomarkers in Subjects With Wilson Disease

Wilson Disease

United States, Germany
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

Milrinone in Congenital Diaphragmatic Hernia

Persistent Pulmonary Hypertension of the Newborn | Congenital Diaphragmatic Hernia | Hypoxemic Respiratory Failure | Pulmonary Hypoplasia

United States
Medway NHS Foundation Trust

Recruiting

Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes (ULOOP)

Hypoxic-Ischemic Encephalopathy | Admission to Neonatal Unit | Stillbirth | Small for Gestational Age at Delivery

United Kingdom
Orphalan

Completed

Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease

Wilson Disease

United States, United Kingdom, Belgium, Brazil, Denmark, France, Germany, Italy, Poland
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
Alexion Pharmaceuticals, Inc.

Completed

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Wilson Disease

United States, Spain, United Kingdom, New Zealand, Denmark, Russian Federation, Canada, Singapore
University College, London

Unknown

TTP and aHUS in Complicated Pregnancies

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura | Thrombocytopenia | Pre-Eclampsia | HELLP Syndrome | Stillbirth | Atypical Hemolytic Uremic Syndrome | IUGR

United Kingdom
Kyowa Kirin, Inc.

Completed

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Masonic Cancer Center, University of Minnesota

Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States
Orphalan

Active, not recruiting

Real World Evidence Study in Subjects With Wilson's Disease (REASON)

Wilson Disease

United States
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Stephen G. Kaler, MD

Recruiting

NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome

Menkes Disease | Occipital Horn Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets Type2

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR); Medical Research Council of...

Terminated

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns (NINOS)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States, Canada
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
MedtronicNeuro

Terminated

InterStim Micro Post Market Clinical Follow-up Study (ELITE)

Overactive Bladder | Fecal Incontinence | Non-obstructive Urinary Retention

United States, Netherlands, France, Canada, Switzerland, United Kingdom
Inozyme Pharma

Recruiting

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency

United States, United Kingdom, Canada
Orphalan

Completed

Study Comparing Once Daily Dose of 900mg of TETA 4HCL Against Cuprior® (450mg Trientine Base, Twice Daily).

Wilson's Disease

United Kingdom
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Alexion Pharmaceuticals, Inc.

Completed

Pharmacokinetic Study of Oral ALXN1840 in Japanese and Non-Japanese Adult Healthy Participants

Wilson Disease

United Kingdom
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

Netherlands, United States, United Kingdom, France
Ultragenyx Pharmaceutical Inc

Active, not recruiting

Study of UX701 Gene Transfer for the Treatment of Wilson Disease

Wilson Disease

United States, Canada, Spain, Portugal, United Kingdom
Homerton University Hospital NHS Foundation Trust
Barts & The London NHS Trust

Recruiting

Function Following Laser for Anal Intraepithelial Neoplasia (FLAN) (FLAN)

Post Operative Pain | Fecal Incontinence | Anal Intraepithelial Neoplasia | Anus Cancer

United Kingdom
Ultragenyx Pharmaceutical Inc

Terminated

Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson Disease

Wilson Disease | Ornithine Transcarbamylase Deficiency | Glycogen Storage Disease Type IA

Spain, United Kingdom, Canada, United States, Brazil
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

United States, Korea, Republic of, Japan, Ireland, United Kingdom, France, Italy
Univar BV

Unknown

Study to Assess Long-Term Outcomes of Trientine in Wilson Disease Patients Withdrawn From Therapy With d-Penicillamine

Wilson Disease

United Kingdom, Germany, Greece, Italy
Inozyme Pharma

Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency (ENERGY)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency

United States, United Kingdom
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

Korea, Republic of, Canada, United States, Australia, Japan, United Kingdom, Sweden

Clinical Trials on Fetal Hydrops in United States

Sponsors and Collaborators

Medical Conditions

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CROs in Russia

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