Clinical Trials on Functional Mitral Regurgitation

Total 22616 results

Michele De Bonis

Completed

Is Mitral Annuloplasty an Effective Treatment for Severe Atrial Functional MR?

Mitral Regurgitation

Italy
Henry Ford Health System

Completed

Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair

Mitral Regurgitation

United States
Edwards Lifesciences

Completed

MITRAFIT- Cardinal Adjustable Mitral Repair Follow-up International Postmarketing Surveillance (PMS) (MITRAFIT)

Mitral Regurgitation

Germany, Italy
Population Health Research Institute

Completed

A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and Efficacy (PREMISE)

Mitral Regurgitation

Canada
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Manchester Metropolitan University

Completed

Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance (PMVI-PiP)

Mitral Regurgitation | Mitral Valve Insufficiency

United Kingdom
University Hospital, Basel, Switzerland
Schweizerische Herzstiftung

Active, not recruiting

Prognosis in Asymptomatic Mitral Regurgitation (PAMIR) Study

Mitral Regurgitation

Germany, Switzerland
Cardiovalve Ltd.

Withdrawn

Feasibility Study of Patients With Severe MR Treated With the Cardiovalve TMVR System

Mitral Regurgitation

Greece, Poland
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Third Affiliated Hospital... and other collaborators

Not yet recruiting

Enhanced External Counter Pulsation on Afterload Mismatch Rate in Post-TEER (PAMPER)

Mitral Regurgitation

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Recruiting

TEER for Severe DMR of Low to Intermediate Surgery Risk

Mitral Regurgitation

China
ITMO University

Recruiting

Mitral Splay Sign, Its Mechanism and Association With Severity of Regurgitation

Mitral Regurgitation

Russian Federation
Peijia Medical Technology (Suzhou) Co., Ltd.
West China Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China

Mitral Regurgitation

China
Medtronic Cardiovascular

Recruiting

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial (APOLLO-EU)

Mitral Regurgitation

Spain, Denmark, France, United Kingdom, Germany, Netherlands, Switzerland
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry (PRIME-MR)

Mitral Regurgitation

United States, France, Germany
Rabin Medical Center

Recruiting

Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair (MITRA-EF)

Mitral Regurgitation

Israel
Medical University of Vienna
LSI SOLUTIONS, Inc.

Recruiting

Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair

Mitral Regurgitation | Mitral Valve Insufficiency

Austria
HighLife SAS

Recruiting

HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve (HighFLO)

Mitral Regurgitation

Belgium, France, Poland, Germany, Australia, United Kingdom
Montefiore Medical Center

Recruiting

Use of Phenylephrine for Assessment of Mitral Regurgitation Severity

Mitral Regurgitation

United States
Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
University Hospital, Essen

Completed

Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort (OneForAll)

Mitral Regurgitation

Germany
Cardiac Dimensions Pty Ltd

Withdrawn

Carillon Mitral Contour System for Treatment of Exercise Induced Functional Mitral Regurgitation (EXERCISE FMR)

Mitral Regurgitation
Hangzhou Valgen Medtech Co., Ltd

Enrolling by invitation

Dragonfly-M Early Feasibility Study

Mitral Regurgitation

China
Hospices Civils de Lyon

Withdrawn

Acquisition of Objective Data During Transapical Neochordae Implantation (TENSCHORD)

Mitral Regurgitation | Mitral Valve Insufficiency
Hangzhou Valgen Medtech Co., Ltd

Unknown

Safety and Performance Study of the MitralStitch Repair System.

Mitral Regurgitation

China
Valcare Medical Ltd.

Completed

AMENDTM Mitral Valve Repair System, Annuloplasty Ring Applied in a Transcatheter Method

Mitral Regurgitation

Israel, Italy, Czechia, Belgium
Abbott Medical Devices
Abbott

Terminated

MitraClip System in Australia and New Zealand (MitraClipANZ)

Mitral Regurgitation

Australia
Mayo Clinic

Completed

Angiotensin-II Blockade in Mitral Regurgitation

Mitral Regurgitation

United States
Mayo Clinic
AstraZeneca

Completed

A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.

Heart Valve Diseases

United States
Enlight Medical Technologies (Shanghai) Co., Ltd

Active, not recruiting

Clinical Study of NovoClasp for Treating Moderate to Severe and Severe Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Polares Medical SA

Terminated

Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR)

Degenerative Mitral Valve Disease

United States
Michele De Bonis

Completed

Commissural Closure to Treat Severe Mitral Regurgitation: Standing the Test of Time.

Degenerative Mitral Valve Disease

Italy
Hangzhou Valgen Medtech Co., Ltd

Enrolling by invitation

Safety and Effectiveness Study of Dragonfly System for Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease
Abbott Medical Devices

Recruiting

MitraClip REPAIR MR Study

Mitral Valve Regurgitation

Canada, United States, Switzerland, Germany
Shanghai NewMed Medical Co., Ltd.

Completed

Mi-thos® Transcatheter Mitral Valve Replacement(First-in-Man Study)

Mitral Valve Regurgitation

China
Mvrx, Inc.

Active, not recruiting

Treatment of Heart Failure and Associated Functional Mitral Valve Regurgitation (MAVERIC)

Mitral Valve Regurgitation

Latvia, Australia, United Kingdom, France, Italy
Neovasc Inc.

Active, not recruiting

Tiara™ Transcatheter Mitral Valve Replacement Study (TIARA-II)

Mitral Valve Regurgitation

Spain, Italy, Germany, Israel, Netherlands, United Kingdom
MValve Technologies Ltd

Unknown

Mitral Valve Replacement With MValve Dock and Lotus (DOCK 1)

Mitral Valve Regurgitation

France, Brazil, Germany, Poland
Abbott Medical Devices

Recruiting

Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation (RESOLVE-MR)

Mitral Valve Regurgitation

Norway, United Kingdom, Saudi Arabia, France, Germany, Italy, Austria, Belgium, Czechia, Israel, Netherlands, Spain, Switzerland
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
Epygon

Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Mitral Valve Regurgitation

Spain, Austria, Italy, Serbia
Edwards Lifesciences

Active, not recruiting

The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study (CLASP)

Mitral Valve Regurgitation

United States, Greece, Canada, Australia, Germany, Italy, Switzerland
HighLife SAS
MedPass International; ICON plc

Active, not recruiting

HighLife™ Transcatheter Mitral Valve Replacement System Study

Mitral Valve Insufficiency | Mitral Valve Regurgitation

France, Germany
Michele De Bonis

Completed

Validation of the EuroSCORE II in Open and Trans-catheter Mitral Valve Repair.

Mitral Valve Regurgitation

Italy
Mitralix

Completed

MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM Study (MERIT)

Mitral Valve Regurgitation

Belgium
University of Ulm

Completed

Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR)

Mitral Valve Regurgitation

Germany
Odense University Hospital
University of Southern Denmark; Danish Heart Foundation

Unknown

Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI) (HEMI)

Mitral Valve Regurgitation

Denmark
MiCardia Corporation

Unknown

Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation (DYANA)

Mitral Valve Regurgitation

Germany, Netherlands, Canada
Fondazione GISE Onlus
University of Padova; Abbott

Recruiting

GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4

Mitral Valve Regurgitation

Italy
Shanghai NewMed Medical Co., Ltd.

Recruiting

Mi-thos® Transcatheter Mitral Valve Replacement Study

Mitral Valve Regurgitation

China

Clinical Trials on Functional Mitral Regurgitation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Jamaica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations