Clinical Trials on Functional Impairment

Total 6883 results

Dr. Jose Antonio SERRA-REXACH
Instituto de Salud Carlos III

Completed

Physical Training in Hospitalized Elderly (AGECAR)

Functional Impairment

Spain
VA Office of Research and Development
VHA Geriatrics and Extended Care; US Department of Health and Human Services... and other collaborators

Completed

Evaluation of Veteran-Directed Home and Community Based Services (VD-HCBS Eval)

Caregiving | Functional Impairment

United States
Providence VA Medical Center
US Department of Veterans Affairs

Unknown

Disseminating a Dashboard for VA Purchased Community Nursing Homes (CNHDashboard)

Veterans | Nursing Home | Quality of Care | Functional Impairment
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
Centro Hospitalar do Porto

Unknown

Independence in Self Care - A Program Focused on Nursing Care

Activities of Daily Living | Hospitalization | Nursing Care | Functional Impairment

Portugal
Centre for Probe Development and Commercialization
St. Joseph's Healthcare Hamilton; McMaster University

Completed

A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function

Renal Function Impairment

Canada
VA Office of Research and Development

Active, not recruiting

Optimizing Function and Independence Through iHI-FIVES

Cognitive Impairment | Functional Impairment

United States
VA Office of Research and Development

Not yet recruiting

A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings

Frailty | Functional Impairment

United States
Fundacion Miguel Servet

Unknown

Functional and Cognitive Impairment Prevention for Elderly Hospitalized Patients

Cognitive Impairment | Elderly | Functional Impairment

Spain
Xuzhou Central Hospital
The Affiliated Hospital of Xuzhou Medical University

Not yet recruiting

rTMS in the Prevention and Treatment of Postoperative Executive Dysfunction

Functional Magnetic Resonance Imaging | Executive Function Disorder
Vasopharm GmbH
Winicker Norimed GmbH

Completed

Effects of the NO-synthase Inhibitor VAS203 on Renal Function in Healthy Volunteers

Renal Function Impairment in Healthy Volunteers

Germany
University of Nimes

Not yet recruiting

Evaluation of Three School-based Mental Health Preventive Interventions in France

Wellbeing | Emotional Distress | Psychosocial Problem | Functional Impairment | User Experience

France
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
National Yang Ming University

Unknown

Interactive Stepping Exercise on Memory

Cognitive Function | Executive Function | Amnestic Mild Cognitive Impairment | Memory | Interactive Stepping Exercise
University of Rochester
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Hormones and Cognition in the Menopausal Transition

Alteration of Cognitive Function | Age-associated Memory Impairment

United States
Federal University of Vicosa

Completed

Eccentrically Reinforced Resistance Training vs. Traditional Resistance Training in Sedentary Older Women

Depression | Executive Function | Physical Functional Performance

Brazil
Eisai Inc.

Completed

A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg)

Hepatic Impairment | Hepatic Function

United States
VA Office of Research and Development

Recruiting

BEAST: A Pilot Trial (BEAST)

Anxiety Sensitivity | Functional Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Daiichi Sankyo, Inc.

Completed

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Hepatic Impairment | Moderate Impaired Hepatic Function

United States
Toronto Metropolitan University
Mitacs

Recruiting

Adaptive Music Therapy for Psychosocial and Cognitive Functions of Older Adults (AMT)

Stress, Psychological | Loneliness | Emotion Regulation | Well Being | Executive Functions | Functional Abilities

Canada
University of Salamanca

Not yet recruiting

Effects of a Daily Cognition Training in Older Adults Without Cognitive Impairment

Cognitive Impairment | Functional Status | Occupational Therapy

Spain
National Central University

Completed

Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.

Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function

Taiwan
Universidad Europea de Madrid

Completed

Effectiveness of a Program Based on Observation-action Training (AOT) in Patients With Cognitive Impairment.

Cognitive Impairments

Spain
VA Office of Research and Development

Completed

Video-Enhanced Care Management for Medically Complex Veterans

Multimorbidity | Cognitive Impairments

United States
University of Novi Sad, Faculty of Sport and Physical...

Completed

Molecular Hydrogen for Cognitive Function and Performance in Elderly

Aging | Cognitive Impairments

Serbia
School of Health Sciences Geneva
University of Lausanne Hospitals; University of Geneva, Switzerland

Recruiting

Orchestra in Class, a Novel Booster for Executive Functions and Brain Development in Young Primary School Children (ORBIT)

Magnetic Resonance Imaging | Behavior | Functional Magnetic Resonance Imaging | Music | Development, Child | Brain Imaging | Executive Functions | Brain Plasticity | Interventions | Arts | Structural Brain Connectivity

Switzerland
Chinese University of Hong Kong

Completed

Air Purifier to Improve Endothelial Function and Carotid Intima Thickness

Cognitive Impairment | Endothelial Function

Hong Kong
UCB Pharma
Parexel

Completed

Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients

Healthy Subjects | Renal Impairments

Japan
Yuhan Corporation

Completed

A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects

Healthy Volunteer | Renal Impairments

Korea, Republic of
VA Office of Research and Development

Recruiting

Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events (CAC)

Moral Injury | Functional Impairment

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics Study of Asciminib in Subjects With Impaired Renal Function Compared to Matched Healthy Volunteers

Renal Impairment

Germany, Bulgaria
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Marmara University

Completed

The Effectiveness of Transcutaneous Electrical Nerve Stimulation After Thoracic Surgery

Pain | Surgery | Pulmonary Function | Functional Capacity | Thoracic
Cairo University

Recruiting

Effect Of Smart Phone Addiction On Pulmonary Function, And Functional Capacity In Children

Pulmonary Function | Functional Capacity | Smartphone Addiction | School Age Children

Egypt
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Zhejiang University

Recruiting

MIND Diet and Cognitive Function in Adults With MCI

Mild Cognitive Impairment | Cognitive Function | Cognitive Decline

China
University of Seville

Unknown

Effect of Strength Training on Executive Functions in Elderly People With Mild Cognitive Impairment (Executive-19)

Executive Function | Strength Training

Spain
Centre for Addiction and Mental Health

Completed

Cognitive Remediation Therapy for Participants With Late-Life Schizophrenia

Schizophrenia | Cognitive Deficit | Cognitive Remediation | Functional Impairment | Late Life Schizophrenia

Canada
Pusan National University Yangsan Hospital

Completed

Effects of Photobiomodulation on Changes in Cognitive Function and rCBF in MCI

Mild Cognitive Impairment | Cognitive Function | Regional Cerebral Blood Flow

Korea, Republic of
Science and Research Centre Koper
Albert Einstein College of Medicine; University of Primorska; Vrije Universiteit...

Completed

Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity (GIBKOP)

Cognitive Impairment | Aging | Cognitive Decline | Motor Coordination or Function

Slovenia
Hamamatsu University

Suspended

Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia

Schizophrenia | Negative Symptoms | Cognitive Impairments

Japan
The Hong Kong Polytechnic University

Completed

Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia

Cognitive Impairment | Executive Function | Efficacy | Schizophrenia; Psychosis | Randomized Controlled Trial

Hong Kong
University of Chile
National Fund for Research and Development in Health, Chile; Fondo Nacional...

Completed

Early Occupational Therapy for Delirium Prevention in Older Patients Admitted to Critical Care Unit

Delirium | Alteration of Cognitive Function | Incompetence, Functional

Chile
Larry J. Siever
New York State Psychiatric Institute

Unknown

Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder (SPD)

Schizotypal Personality Disorder | Cognitive Impairments

United States
Shanghai Mental Health Center

Recruiting

Influence Factors and Cognitive Characteristics in Unipolar and Bipolar Depression:Based on the THINC-it Tool

Cognitive Impairments

China
Chinese PLA General Hospital
Beijing Tiantan Hospital

Recruiting

The Evolution and Prognosis of Moyamoya Disease

Cognitive Impairment | Moyamoya Disease | Functional Impairment | Revascularization

China

Clinical Trials on Functional Impairment

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